{"status":"ok","message-type":"work-list","message-version":"1.0.0","message":{"facets":{},"total-results":39,"items":[{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:13:22Z","timestamp":1753884802805,"version":"3.41.2"},"reference-count":24,"publisher":"Open Access Pub","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>In this research work Mg0.45Mn0.55-xNixFe2O4 ferrite particles of varying compositions (x=0.05, x=0.15, x=0.25, x=0.45 and x=0.55) were synthesized using cost effectual co-precipitation route. The synthesized ferrite particles were characterized by collection of techniques. XRD analysis confirmed the formation of cubic spinel structure of the ferrite particles. SEM and AFM analyses illustrated the morphology and size distribution of obtained ferrite particles. FT-IR study exposed that the absence of any additional peak related to second phase. VSM results indicated magnetic analyses such as saturation magnetization (MS), Coercivity (HC) and Remanence (Mr) of ferrite particles. The major objective of the present investigation is to synthesize MgMnNiFe2O4 ferrite particles on cotton fabrics in order to obtain finished fabrics; it is very significant in biological applications. The antibacterial activities of the ferrite particles coated cotton fabrics were tested against selected Gram positive and Gram negative bacteria which showed tremendous results via formation of inhibition zones. The fabricated ferrite particles on cotton fabrics showed great durability evidenced by their antibacterial activities even after 20 washing cycles. Hence, the functionalized cotton fabrics could be used as potential antibacterial agent.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-22-4179","type":"journal-article","created":{"date-parts":[[2022,12,24]],"date-time":"2022-12-24T04:08:45Z","timestamp":1671854925000},"page":"30-43","source":"Crossref","is-referenced-by-count":0,"title":["Antibacterial Activities of Ni Substituted Ferrite Particles for Biological Applications"],"prefix":"10.14302","volume":"2","author":[{"given":"Subbiah Rammohan","family":"Chitra","sequence":"first","affiliation":[{"name":"Head of Physics Department, P.K.N Arts and Science College, Tirumangalam in Madurai District, Tamilnadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suruliappan Subramanian","family":"Anjanapriya","sequence":"additional","affiliation":[{"name":"Assistant Professor in Microbiology Department, P.K.N Arts and Science College, Tirumangalam in Madurai District, Tamilnadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"key":"ref0","unstructured":"1.Shahzeidi Z S, Amiri Gh. (2015) Antibacterial activity of Fe3O4nanoparticles. , Int. J. Bio-Inorg. Hybr. Nanomater 4(3), 135-140."},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2.Katerina. (2009) Superparamagnetic maghemite nanoparticles from solid-state synthesis \u2013 Their functionalization towards peroral MRI contrast agent and magnetic carrier for tryps in immobilization. , Biomaterials 30(15), 2855-2863.","DOI":"10.1016\/j.biomaterials.2009.02.023"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3.Vishal. (2016) Synthesis and characterization of nickel cobalt ferrite nanoparticles via heat treatment method. Advance Materials Proceedings 1(1), 76-80.","DOI":"10.5185\/amp.2016\/114"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4.Wu Wei. (2008) Quanguo He and Changzhong Jiang, Magnetic Iron Oxide Nanoparticles: Synthesis and Surface Functionalization Strategies, Nanoscale Res. , Lett 3, 397-415.","DOI":"10.1007\/s11671-008-9174-9"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5.Szostak-Kotowa J. (2004) Biodeterioration of textiles. , Int. Biodeterior. Biodegrad 53, 165-170.","DOI":"10.1016\/s0964-8305(03)00090-8"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6.Subbiah Rammohan Chitra, Sendhilnathan Sechasalom. (2015) Structural and Electrical Properties of Ni-Substituted Mg-Mn Nanoferrite by Coprecipitation Route\u2019. , Int. J. Appl. Ceram. Technol 12(3), 643-651.","DOI":"10.1111\/ijac.12242"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"7.El-Rafie. (2010) Antimicrobial effect of silver nanoparticles produced by fungal process on cotton fabrics. , Carbohydr. Polym 80, 779-782.","DOI":"10.1016\/j.carbpol.2009.12.028"},{"key":"ref7","unstructured":"8.Rajendran. (2011) Dyeing and antimicrobial properties of cotton fabrics finished with Punica granatum extracts. , J. Text. Appar. Technol. Manag 7, 1-12."},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"9.Deraz N M, Omar H, Elkader Abd. (2013) Preparation and characterization of nano-magnetic Ni0.5Mg0.5Fe2O4system for Biological applications. , J. pure Appl. Microbiol 7, 339.","DOI":"10.1016\/j.jiec.2013.12.006"},{"key":"ref9","unstructured":"10.Das A R, Ananthan V S, Khan D C. (1985) Wall permeability studies on Ti4+doped Ni-Zn ferrite. , J. Appl. Phys 57, 4189."},{"key":"ref10","unstructured":"11.Vinuthna C, Ravinder D, Madhusudan R. (2013) Characterization of Co1-XZnxFe2O4nano spinal ferrites prepared by citrate precursor method. , Int. Journal of Engineering Research and Applications 3(6), 654-660."},{"key":"ref11","unstructured":"12.Pathan A T, Shaikh A M. (2012) Synthesis and characterization of cobalt substituted Li-Ni-Zn nano ferrites by chemical route. , European Journal of Applied Engineering and Scientific Research 1(4), 173-178."},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"13.Duque. (2007) Magnetic properties of NiFe2O4nanoparticles produced by a new chemical method. , Physica B 398, 287-290.","DOI":"10.1016\/j.physb.2007.04.030"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14.Kneller E F, Hawig R. (1991) The Exchange-Spring Magnet: A New Material Principle for Permanent Magnets. , J. Magn. Magn. Mater 27, 3588-3560.","DOI":"10.1109\/20.102931"},{"key":"ref14","unstructured":"15.Neel L, Annls. (1948) . , Phys 3, 137."},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16.Jacobo S E, Uhalde S D, Bertorello H R. (2004) Rare Earth influence on the structural and magnetic properties of NiZn ferrites. , J. Magn. Magn. Mater 272, 2253-2254.","DOI":"10.1016\/j.jmmm.2003.12.564"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17.Balakumaran. (2016) In vitro biological properties and characterization of nanosilver coated cotton fabrics: An application for antimicrobial textile finishing. , Int. Biodeter. Biodegrad 107, 48-55.","DOI":"10.1016\/j.ibiod.2015.11.011"},{"key":"ref17","unstructured":"18.Sathianarayanan. (2010) Antibacterial finish for cotton fabric from herbal products. , Indian J. Fibre Textile Res 35, 50-58."},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"19.Perelshtein. (2009) Sonochemical coating of silver nanoparticles on textile fabrics (nylon, polyester and cotton) and their antibacterial activity. , Nanotechnol 19, 245705.","DOI":"10.1088\/0957-4484\/19\/24\/245705"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20.Raghupati K R, Koodali R T, Manna A C. (2011) Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles. , Langmuir 27, 4020-4028.","DOI":"10.1021\/la104825u"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"21.Mahapatra. (2008) Ultrafine dispersed CuO nanoparticles and their antibacterial activity. , J. Exp Nanosci 3, 185-193.","DOI":"10.1080\/17458080802395460"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"22.Tran. (2010) Bactericidal effects of iron oxide nanoparticles on Staphylococcus aureus. , Int J. Nanomedicine 5, 277-283.","DOI":"10.2147\/IJN.S9220"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"23.El-Rafie. (2014) Characterization of nanosilver coated cotton fabrics and evaluation of its antibacterial efficacy. , Carbohydr. Polym 107, 174-181.","DOI":"10.1016\/j.carbpol.2014.02.024"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"24.El-Rafie. 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Concentration constants are S0.5 for Hill equation and Km for Michaelis-Menton equation. The graphical approach was proposed in order to go from concentration constant of Hill equation to Michaelis concentration of the process that could be characterized by the same catalytic activity (the same values of minimum and maximum rates) similar to that observed in the process described by Hill equation.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-18-2280","type":"journal-article","created":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T08:22:17Z","timestamp":1537950137000},"page":"94-99","source":"Crossref","is-referenced-by-count":8,"title":["Graphical Approach to Compare Concentration Constants of Hill and Michaelis-Menten Equations"],"prefix":"10.14302","volume":"1","author":[{"given":"Elena","family":"V. Emelyanova","sequence":"first","affiliation":[{"name":"FSBIS G.K. 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Approximately 2 million women are diagnosed with breast cancer in 2018. In Asia, unfortunately Pakistan leads the highest number of breast cancer patients. Various treatment strategies are present but they are not well developed. There is a great need to develop effective methods for early detection and treatment of the disease. For cancer treatment chemotherapeutic interventions have always been a method of choice. One of the mechanisms involved in cancerous cell proliferation is Mevalonate (MVA) pathway. It is hypothesized that arresting MVA pathway leads to cell death hence cancer cell growth is suppressed. Various inhibitors of MVA pathway have been studied that can suppress cell proliferation. Nitrogen containing bisphosphonates are MVA pathway inhibitor and clinically used for treatment of bone diseases. Their anticancer efficacy is also reported. Current study focuses on alendronate, a nitrogen containing bisphosphonate to examine their anticancer effect on breast cancer cell line. Results of this study may help in addition of new anticancer drug for breast cancer.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-19-2953","type":"journal-article","created":{"date-parts":[[2019,9,21]],"date-time":"2019-09-21T10:14:02Z","timestamp":1569060842000},"page":"1-7","source":"Crossref","is-referenced-by-count":4,"title":["Assessment of Anticancer Effect of Alendronate in Breast Cancer: An In vitro Study"],"prefix":"10.14302","volume":"2","author":[{"given":"Nida Syed Amber","family":"Ilyas","sequence":"first","affiliation":[{"name":"National Center for Proteomics, University of Karachi, Karachi 75270, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamshad","family":"Zarina","sequence":"additional","affiliation":[{"name":"National Center for Proteomics, University of Karachi, Karachi 75270, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zehra","family":"Hashim","sequence":"additional","affiliation":[{"name":"National Center for Proteomics, University of Karachi, Karachi 75270, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2019,8,3]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"1.Hanahan D, R A Weinberg. 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PMCID: PMC4377696 ."}],"container-title":["Journal of Biotechnology and Biomedical Science"],"language":"en","link":[{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,21]],"date-time":"2019-09-21T10:14:09Z","timestamp":1569060849000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1136"}},"editor":[{"given":"Aiping","family":"Zheng","sequence":"additional","affiliation":[{"name":"China"}],"role":[{"role":"editor","vocabulary":"crossref"}]}],"issued":{"date-parts":[[2019,8,3]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,8,3]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2576-6694.jbbs-19-2953","ISSN":["2576-6694"],"issn-type":[{"type":"electronic","value":"2576-6694"}],"published":{"date-parts":[[2019,8,3]]},"article-number":"1136"},{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:12:56Z","timestamp":1753884776028,"version":"3.41.2"},"reference-count":36,"publisher":"Open Access Pub","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>The present study aimed to evaluate the effect of the Trivedi Effect\u00ae- Biofield Energy Treated\/Blessed Test formulation\/item (TI) composed of minerals (magnesium, zinc, copper, calcium, selenium, and iron), vitamins (ascorbic acid, pyridoxine HCl, alpha tocopherol, cyanocobalamin, and cholecalciferol), Panax ginseng extract, CBD isolates, and \u03b2-carotene on elasticity of skin, heart, muscle, and neuronal cells in the H9C2 (rat cardiomyocytes), C2C12 (mouse myoblast cells), HaCaT (human keratinocytes), and SH-SY5Y (human neuroblastoma cells) cell line in DMEM medium. The test formulation constituents were divided into two parts; one section was defined as untreated test formulation (UT), while the other portion of test formulation received Biofield Energy Healing\/Blessing Treatment (BT) by a renowned Biofield Energy Healer, Mr. Mahendra Kumar Trivedi. The test items were treated with Biofield Energy Healing\/Blessing Treatment and divided as Biofield Energy Treated\/Blessed (BT) and untreated (UT) test items. MTT data showed that the test formulation in various concentrations was found as safe and nontoxic in the tested concentrations with viability range from 73% to 307%. Young\u2019s modulus (YM) is a measure of cell stiffness, a decrease in YM value indicates increase elasticity of the cells and vice-versa. YM in H9C2 cells were decreased by 9.6% and 66.1% in the BT-DMEM + UT-TI group at 0.1 and 1 \u00b5g\/mL respectively, as compared with untreated test group. However, C2C21 cells showed increased YM by 443.9% at 1 \u00b5g\/mL in the UT-DMEM + BT-TI group, while 869.6% increased YM in the BT-DMEM + UT-TI group at 1 \u00b5g\/mL as compared with untreated test group. However, 314% increased YM was reported in the BT-DMEM + BT-TI group at 1 \u00b5g\/mL as compared with the untreated test group. However, the value of YM was significantly decreased in the HaCaT cell line by 247.7% (at 1 \u00b5g\/mL), 225.8% (at 0.1 \u00b5g\/mL), and 97.9% (at 1 \u00b5g\/mL) in the UT-DMEM + BT-TI, BT-DMEM + UT-TI, and BT-DMEM + BT-TI group respectively, as compared with the untreated group. In addition, YM was significantly decreased in the SH-SY5Y cell line by 92.6%, 18.1%, and 26.6% at 1 \u00b5g\/mL in the UT-DMEM + BT-TI, BT-DMEM + UT-TI, and BT-DMEM + BT-TI group respectively, as compared with the untreated group. Overall, the results showed the significant decreased YM among the SH-SY5Y, HaCaT, and H9C2 cells, while it was increased in the C2C21 cell line. Thus, the mechanical properties of cells such as cellular function, including shape, motility, differentiation, division, and adhesion to its surrounding extracellular matrix were improved. Overall, it can be useful in many disease progressions with improved cellular elasticity and its associated complications\/symptoms.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-21-3819","type":"journal-article","created":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T10:19:00Z","timestamp":1627726740000},"page":"19-29","source":"Crossref","is-referenced-by-count":0,"title":["Elasticity Profile of Skin, Neuronal, Cardiac, and Skeletal Muscle Cells after Treatment with the Biofield Energy Healing-Based Proprietary Test Formulation"],"prefix":"10.14302","volume":"2","author":[{"given":"Mahendra Kumar","family":"Trivedi","sequence":"first","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Branton","sequence":"additional","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dahryn","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Snehasis","family":"Jana","sequence":"additional","affiliation":[{"name":"Trivedi Science Research Laboratory Pvt. Ltd., Thane (W), Maharashtra, India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2021,7,13]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Kuznetsova T G, Starodubtseva M N, Yegorenkov N I, Chizhik S A, Zhdanov R I. (2007) Atomic force microscopy probing of cell elasticity. , Micron 38, 824-833.","DOI":"10.1016\/j.micron.2007.06.011"},{"key":"ref1","unstructured":"2.Pasikowska M, Kobiela T, Duli\u0144ska M I, Eris I. (2015) The impact of anti-aging peptides on mechanical properties of fibroblasts. Proceedings\u201323. IFSCC Conference (http:\/\/tst.pg2.at\/abstracts\/data\/full_papers\/full_paper_134.pdf) , Zurich ."},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3.Kobiela T, Lelen-Kaminska K, Stepulak M, Lekka M, Malejczyk M et al. 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(2012) Elasticity maps of living neurons measured by combined fluorescence and atomic force microscopy. , Biophys J 103(5), 868-877.","DOI":"10.1016\/j.bpj.2012.08.005"}],"container-title":["Journal of Biotechnology and Biomedical Science"],"language":"en","link":[{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T10:19:34Z","timestamp":1627726774000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1662"}},"editor":[{"given":"Fuwen","family":"Yuan","sequence":"additional","affiliation":[{"name":"Duke University, USA"}],"role":[{"role":"editor","vocabulary":"crossref"}]}],"issued":{"date-parts":[[2021,7,13]]},"references-count":36,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,10,29]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2576-6694.jbbs-21-3819","ISSN":["2576-6694"],"issn-type":[{"type":"electronic","value":"2576-6694"}],"published":{"date-parts":[[2021,7,13]]},"article-number":"1662"},{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:11:39Z","timestamp":1753884699768,"version":"3.41.2"},"reference-count":25,"publisher":"Open Access Pub","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>Background\nThe genetic material of the genetically modified crop has been altered to develop the necessary insect resistance features by introducing genes from the Bt (Bacillus thuringiensis) bacterium. The objective of this study was to find smuggled GM Bt crops in the Metema farming area and examine its environmental effects.\n\nMethod\nAn experimental; Completely Randomized Design (CRD) was used to collect crop samples in the study area. The CTAB (Cetyltrimethyl ammonium bromide) technique was used to isolate DNA from all transported samples, and the purity was determined using a Nano Drop spectrophotometer. Conventional PCR with particular primers for different Bt gene events was used to detect the presence of genes. Furthermore, utilizing Bt cotton specific primer sets, the prevalence of GM cotton was measured, and amplified fragments were confirmed using agarose gel electrophoresis.\n\nResult\nThe PCR results revealed that 15 (33.3 percent) of the samples were Bt cotton smuggled from Sudan. The PCR assay also revealed the presence of GM maize. Moreover, the effects of GM genes on the environment were studied in diseased samples, and no transgenes were found. Furthermore, domestic and indigenous crops were used to determine horizontal gene transfers of GM genes to other crops, and the transgene was not found in any of the samples analyzed. Conclusion: In the current study, 28 (13.4%) of the 209 (100%) total analyzed samples were GM crops which indicated the presence of unauthorized GM seeds in the study area. Environmental impact studies and horizontal gene transfer data similarly revealed that the Bt gene was not transferred to other crops and had no harmful environmental effects. For a better understanding of the Impact of imported unauthorized GM seeds, more additional detection of GM events should be done by expanding the sampling site and sample types.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-22-4390","type":"journal-article","created":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T08:54:13Z","timestamp":1705136053000},"page":"16-27","source":"Crossref","is-referenced-by-count":0,"title":["Detection of Smuggled Genetically Modified Crops and Assessment of its Environmental Impact in the Ethio -Sudan Trans Boundary Area, North West Ethiopia"],"prefix":"10.14302","volume":"3","member":"5410","published-online":{"date-parts":[[2023,4,11]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.N A Abdallah. (2014) The story behind Bt cotton: Where does Sudan stand?. 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(2009) Selection and characterization of the Bacillus thuringiensis strains toxic to Spodoptera eridania (Cramer), Spodoptera cosmioides (Walker) and Spodoptera frugiperda (Smith)(Lepidoptera: Noctuidae). , Biological Control 50(2), 157-163.","DOI":"10.1016\/j.biocontrol.2009.03.014"},{"key":"ref22","unstructured":"23.S D. (2007) . Bt cotton. www.utcrops.com\/cotton_insects\/pubs\/Wi29- Btcotton. Accessed on 14-06."},{"key":"ref23","unstructured":"24.Vidhya P, Shree S, Ramanjini H, K N Gowda, Yogendra T et al. (2012) Detection of Gm cotton seeds. , Indian Journal of Biotechnology.11: 176-181."},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"25.Wu H-S, Shi X, Li J, Liu Y-D, Xu Y et al. (2016) Soil ecological safety evaluation for bivalent transgenic cotton plants: root exudates versus soil enzyme activities and soil microbial diversity. Applied ecology and environmental research. 14(2), 319-336.","DOI":"10.15666\/aeer\/1402_319336"}],"container-title":["Journal of Biotechnology and Biomedical Science"],"language":"en","link":[{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1944","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T08:54:27Z","timestamp":1705136067000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1944"}},"issued":{"date-parts":[[2023,4,11]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,2,20]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2576-6694.jbbs-22-4390","ISSN":["2576-6694"],"issn-type":[{"type":"electronic","value":"2576-6694"}],"published":{"date-parts":[[2023,4,11]]},"article-number":"1944"},{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:11:41Z","timestamp":1753884701438,"version":"3.41.2"},"reference-count":41,"publisher":"Open Access Pub","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>L-tryptophan is an essential \u03b1-amino acid, necessary for the normal growth in newborns, nitrogen balance in adults, protein synthesis, precursor of serotonin, melatonin, niacin, and albeit inefficiently in human, also the precursor of indole alkaloids and auxins in plants. This current study was designed to investigate the impact of the Trivedi Effect\u00ae-Biofield Energy Healing Treatment (Blessing) on the structural properties and the isotopic abundance ratio of L-tryptophan using LC-MS analytical technique. L-tryptophan sample was divided into two parts, one part of L-tryptophan was considered as the control sample (no Biofield Energy Treatment was provided), while the second part was treated with the Trivedi Effect\u00ae-Consciousness Energy Healing Treatment\/Blessing remotely by a renowned Biofield Energy Healer, Dahryn Trivedi and termed as the treated sample. The mass spectra of both the control and treated samples with respect to the chromatographic peak at retention time (Rt) 2.1 minutes exhibited the mass of the molecular ion peak adduct with hydrogen ion at m\/z 205.08 (calcd for C11H13N2O2+, 205.1), along with low molecular fragmented mass peaks at m\/z 188, 159, and 102 for C11H12N2O2+, C10H11N2+, and C8H6+, respectively were also observed. The isotopic abundance ratio of PM+1\/PM (2H\/1H or 13C\/12C or 15N\/14Nor17O\/16O) in the treated L-tryptophan was significantly increased by 35.93% compared with the control sample. Hence,the 13C, 2H, 15N, and 17O contributions from C11H13N2O2+ to m\/z 206.08 in the treated L-tryptophan was significantly increased compared to the control sample. It could be hypothesized that the changes in the isotopic abundance and mass peak intensities due to the modification in nuclei possibly through the interference of neutrino particles using the Trivedi Effect\u00ae-Consciousness Energy Healing Treatment. The Biofield Energy Treated\/Blessed L-tryptophan with increased stable isotopic abundance ratio might have changed the physicochemical properties with higher force constant in the molecule. The new form of treated L-tryptophan would be a better and more stable in the supplements, nutraceutical, and pharmaceutical formulations, which would be advantageous for the prevention and treatment of pellagra, depression, kynurenine. It could also maintain the normal label of tryptophan and avoid increase of its metabolite, lower the neurotoxin and a metabotoxin behavior, glutaric aciduria type I (glutaric acidemia type I) disorder, eosinophilia-myalgia syndrome (EMS), incurable and sometimes fatal flu-like neurological condition, etc. As tryptophan is the precursor for the plant hormones like indole alkaloids and auxins, hence, this treated L-tryptophan would be advantageous for the improvement of yield, productivity, and quality of crops and other plants.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-21-3773","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T14:19:45Z","timestamp":1620051585000},"page":"10-18","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of the Isotopic Abundance Ratio of Consciousness Energy Healing Treated L-Tryptophan Using LC-MS Spectrometry"],"prefix":"10.14302","volume":"2","author":[{"given":"Dahryn","family":"Trivedi","sequence":"first","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahendra Kumar","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Branton","sequence":"additional","affiliation":[{"name":"Trivedi Global, Inc., Henderson, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Snehasis","family":"Jana","sequence":"additional","affiliation":[{"name":"Jana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"unstructured":"1. 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(2015) Antimicrobial sensitivity pattern ofPseudomonas fluorescensafter biofield treatment. , J Infect Dis Ther 3, 222.","key":"ref25","DOI":"10.4172\/2332-0877.1000222"},{"doi-asserted-by":"publisher","unstructured":"27.Trivedi M K, Branton A, Trivedi D, Nayak G, Gangwar M et al. (2015) Agronomic characteristics, growth analysis, and yield response of biofield treated mustard, cowpea, horse gram, and groundnuts. , International Journal of Genetics and Genomics 3, 74-80.","key":"ref26","DOI":"10.11648\/j.ijgg.20150306.13"},{"doi-asserted-by":"publisher","unstructured":"28.Kinney J P, Trivedi M K, Branton A, Trivedi D, Nayak G et al. (2017) Overall skin health potential of the biofield energy healing based herbomineral formulation using various skin parameters. , American Journal of Life Sciences 5, 65-74.","key":"ref27","DOI":"10.11648\/j.ajls.20170502.15"},{"unstructured":"29.Singh J, Trivedi M K, Branton A, Trivedi D, Nayak G et al. 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Seeds By Neutron Activation Analysis"],"prefix":"10.14302","volume":"1","author":[{"given":"Al-Bachir","family":"M.","sequence":"first","affiliation":[{"name":"1 Radiation Technology Dep. Atomic Energy Commission of Syria."},{"name":"* corresponding author"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarhil","family":"A.","sequence":"additional","affiliation":[{"name":"2 Nuclear Engineering Dep. Atomic Energy Commission of Syria."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al-Haddad","family":"Th.","sequence":"additional","affiliation":[{"name":"3 Faculty of Science, Damascus University, Damascus, Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2018]]},"reference":[{"key":"ref001","doi-asserted-by":"crossref","unstructured":"1. 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Under the influence of such detrimental stresses, a drastic alteration in a plant's osmotic requirements, hormonal production, shedding of leaves, and closure of stomata, along with a lessening in the diffusion and transportation of CO2 and H2O are commonly seen. This review unfolds with a description of the basic methodology involved in the proteomic analysis of various proteins involved in stress response along with a brief idea on identifying and obtaining a genomic sequence for proteomic studies. It then dives deep into understanding the impact of abiotic stresses such as salinity, drought and high temperatures on cereal crops such as rice and sorghum as well as the internal dynamics of tolerance mechanism unfolding during stresses have also been described. Extensive literature describing the proteomic and physiological responses to primary and secondary effects of salt stress in cereal crops emphasizing on ROS production and apoptosis, the role of osmolytes as ROS scavengers during osmotic stress and vacuolar antiporters in ionic stress along with the responses during drought stress such as the accumulation of LEA proteins and ABA-based signaling has been reviewed and critically discussed. The study also sheds light on some experimental proteomic studies conducted on the seedlings, root tissues, and shoots of rice cultivars.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-20-3525","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T09:38:35Z","timestamp":1600076315000},"page":"43-59","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Drought and Salt Stress on Cereal Crop Plants and their Proteomic and Physiological Studies"],"prefix":"10.14302","volume":"2","author":[{"given":"Kaligotla Venkata Subrahmanya","family":"Anirudh","sequence":"first","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, GITAM Deemed to be University, Gandhi Nagar Campus, Rushikonda, Visakhapatnam - 530045 (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanushree","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, GITAM Deemed to be University, Gandhi Nagar Campus, Rushikonda, Visakhapatnam - 530045 (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh K.","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, GITAM Deemed to be University, Gandhi Nagar Campus, Rushikonda, Visakhapatnam - 530045 (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasim","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, GITAM Deemed to be University, Gandhi Nagar Campus, Rushikonda, Visakhapatnam - 530045 (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2020,9,8]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Ashraf M, Harris P J C. 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Zarkani A A Antimicrobial activity of Hibiscus sabdariffa and Sesbania grandiflora extracts against some G\u2013ve and G+ve strains 2016 Banat\u2019s Journal of Biotechnology 7 13 17 23","DOI":"10.7904\/2068-4738-VII(13)-17"}],"container-title":["Journal of Biotechnology and Biomedical Science"],"language":"en","link":[{"URL":"https:\/\/openaccesspub.org\/article\/940\/pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openaccesspub.org\/article\/940\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/940","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:55:49Z","timestamp":1760705749000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/biotechnology-and-biomedical-science\/article\/940"}},"issued":{"date-parts":[[2018]]},"references-count":45,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2576-6694.jbbs-18-2489","ISSN":["2576-6694"],"issn-type":[{"value":"2576-6694","type":"electronic"}],"published":{"date-parts":[[2018]]}},{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:11:23Z","timestamp":1753884683531,"version":"3.41.2"},"reference-count":20,"publisher":"Open Access Pub","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>Chalkley counting has been regarded as a relatively reliable method of quantifying tumor angiogenesis. In this study we investigated the reliability of Chalkley counting in quantifying tumor angiogenesis in oral tongue squamous cell carcinoma (OTSCC) using CD34; and tumor vasculogenesis using angiotensin converting enzyme, angiotensin II receptor 1 and angiotensin II receptor 2, in 32 OTSCC samples. Chalkley counting was performed by two independent observers. The averages of three \u2018hot spot\u2019 counts were compared with known prognostic factors. All four markers showed no correlation with any of the prognostic factors. When comparing the results from the two independent observers, the only marker shown to have a significant moderate correlation was CD34. The other three markers showed no significant correlation. The lack of statistical significance between the independent observers, and known prognostic factors with the four markers used, shows that Chalkley counting is not a reliable prognostic tool in OTSCC.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-19-2625","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T13:03:23Z","timestamp":1551704603000},"page":"44-54","source":"Crossref","is-referenced-by-count":0,"title":["Chalkley Counting in Oral Tongue Squamous Cell Carcinoma:Does It have A Prognostic Value?"],"prefix":"10.14302","volume":"1","author":[{"given":"Paul","family":"Campbell","sequence":"first","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reuben","family":"Bennet","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louisa Joyce","family":"Lim","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen D","family":"Brasch","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reginald","family":"Marsh","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reginald","family":"Marsh","sequence":"additional","affiliation":[{"name":"University of Auckland, Auckland, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tinte","family":"Itinteang","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swee T","family":"Tan","sequence":"additional","affiliation":[{"name":"Gillies McIndoe Research Institute, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swee T","family":"Tan","sequence":"additional","affiliation":[{"name":"Wellington Regional Plastic, Maxillofacial and Burns Unit, Hutt Hospital, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2019,3,4]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. 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The quantification of angiogenesis in relation to metastasis in oral cancer: A review. Int J Oral Maxillofac Surg 33: 2-7.","DOI":"10.1054\/ijom.2003.0433"}],"container-title":["Journal of Biotechnology and Biomedical Science"],"language":"en","link":[{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T23:38:31Z","timestamp":1663025911000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/openaccesspub.org\/jbbs\/article\/1014"}},"editor":[{"given":"Hammad","family":"Afzal","sequence":"additional","affiliation":[{"name":"SZABIST, Karachi, Pakistan."}],"role":[{"role":"editor","vocabulary":"crossref"}]}],"issued":{"date-parts":[[2019,3,4]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,9,30]]}},"URL":"https:\/\/doi.org\/10.14302\/issn.2576-6694.jbbs-19-2625","ISSN":["2576-6694"],"issn-type":[{"type":"electronic","value":"2576-6694"}],"published":{"date-parts":[[2019,3,4]]},"article-number":"1014"},{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:02:28Z","timestamp":1778695348864,"version":"3.51.4"},"reference-count":65,"publisher":"Open Access Pub","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JBBS"],"abstract":"<jats:p>Callus and biomass culture of Catharanthus roseus L. were established to check for the presence of total alkaloid and its subsequent yield. Various treatments like strength of nutrient salts, sucrose concentrations and combinations of plant growth regulators (PGR\u2019s) were applied to both MS and B5 in agar as well as suspension medium to test their effects on enhanced alkaloid content and its yield. There was no significant difference in any of the observable parameters of fresh wt, dry wt, alkaloid content, production, productivity and yield if the culture were treated similarly in both types of media formulations (MS or B5 salts). Physical state (agar solidified or the liquid suspension) of the medium had significant effect on all the parameters particular on fresh wt, alkaloid content and yields. Although, the fresh wt. and dry wt. of biomass in suspension culture was 2-3 times less than that of callus obtained from agar medium. However, the alkaloid content and yield was 2-3 times higher in suspension culture compared to agar medium in similar treatments. The highest alkaloid content observed was 5.67mg\/g dwt in B5 suspension medium containing 3% sucrose and modified with 0.5mg\/l 2,4-Dichlorophenoxy acetic acid (2,4-D) + 1 mg\/l Kinetin (KIN) + 2mg\/l \u03b1- naphthalene acetic acid (NAA). The combined effects of these factors on the enhanced production of total alkaloids were expected to contain higher yield of anticancer vinblastine and vincristine in the cell suspension culture system.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-18-2475","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T11:15:56Z","timestamp":1545131756000},"page":"14-34","source":"Crossref","is-referenced-by-count":21,"title":["Enhanced Alkaloid Production from Cell Culture System of Catharanthus roseus in Combined Effect of Nutrient Salts, Sucrose and Plant Growth Regulators"],"prefix":"10.14302","volume":"1","author":[{"given":"Malay Ranjan","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, Gandhi Institute of Technology and Management, (GITAM) (Deemed to be University), Rushikonda, Visakhapatnam (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh Kumar","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, Gandhi Institute of Technology and Management, (GITAM) (Deemed to be University), Rushikonda, Visakhapatnam (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasim","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, GITAM Institute of Technology, Gandhi Institute of Technology and Management, (GITAM) (Deemed to be University), Rushikonda, Visakhapatnam (A.P.), India."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2018,12,8]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Pan Q, Mustafa N R, Tang K, Choi Y H, Verpoorte R. 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In the interface between the body and the environment, the respiratory pathway is particularly stressed from an allergological perspective. Under the relationship between energy and matter signed by Einstein, it is possible to approach patients suffering from allergies with an Electraceutical 1 administration in a quantum modality.<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-24-5001","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T12:01:48Z","timestamp":1715342508000},"page":"1-16","source":"Crossref","is-referenced-by-count":0,"title":["Quantum Approach to Allergic Pathology"],"prefix":"10.14302","volume":"3","author":[{"given":"Piergiorgio","family":"Spaggiari","sequence":"first","affiliation":[{"name":"Scientific medical association, between biochemistry and biophysics, accredited to the Italian Ministry of Health"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Tribbia","sequence":"additional","affiliation":[{"name":"Regional manager of AMBB, responsible for the Lombardy region, Milan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pisano","family":"Gianpaolo","sequence":"additional","affiliation":[{"name":"Scientific medical association, between biochemistry and biophysics, accredited to the Italian Ministry of Health"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5410","published-online":{"date-parts":[[2024,4,27]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Famm K. 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This research shows the presence of potent secondary metabolites present in the leaves of senna occidentalis (leaves).<\/jats:p>","DOI":"10.14302\/issn.2576-6694.jbbs-19-2791","type":"journal-article","created":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T12:06:50Z","timestamp":1559218010000},"page":"12-21","source":"Crossref","is-referenced-by-count":22,"title":["Phytochemical Analysis and Thin Layer Chromatography Profiling of Crude Extracts from Senna Occidentalis(Leaves)"],"prefix":"10.14302","volume":"2","author":[{"given":"Lawal","family":"A.M","sequence":"first","affiliation":[{"name":"Department of Chemistry, Federal University Dutse, Jigawa State, P.M.B 7156"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullahi","family":"R","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Federal University Dutse, Jigawa State, P.M.B 7156"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"M.S","sequence":"additional","affiliation":[{"name":"Department of Polymer and Textile Engineering, Ahmadu Bello University, Zaria, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurfi","family":"M.Y","sequence":"additional","affiliation":[{"name":"Department of Pure and Industrial Chemistry, Bayero University Kano"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalid","family":"A","sequence":"additional","affiliation":[{"name":"Science Department, Great Icon International School, Zaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuhu","family":"M","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Federal University Dutse, Jigawa State, P.M.B 7156"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5410","published-online":{"date-parts":[[2019,5,29]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.Ahn K. 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