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Trans. R. Soc. Lond. B"],"published-print":{"date-parts":[[1999,5,29]]},"abstract":"<jats:p>The M. pectoralis (pars thoracicus) of pigeons (<jats:italic>Columba livia<\/jats:italic>) is comprised of short muscle fibres that do not extend from muscle origin to insertion but overlap \u2018in-series\u2019. Individual pectoralis motor units are limited in territory to a portion of muscle length and are comprised of either fast twitch, oxidative and glycolytic fibres (FOG) or fast twitch and glycolytic fibres (FG). FOG fibres make up 88 to 90% of the total muscle population and have a mean diameter one-half of that of the relatively large FG fibres. Here we report on the organization of individual fibres identified in six muscle units depleted of glycogen, three comprised of FOG fibres and three comprised of FG fibres. For each motor unit, fibre counts revealed unequal numbers of depleted fibres in different unit cross-sections. We traced individual fibres in one unit comprised of FOG fibres and a second comprised of FG fibres. Six fibres from a FOG unit (total length 15.45 mm) ranged from 10.11 to 11.82 mm in length and averaged (\u00b1s.d.) 10.74\u00b10.79 mm. All originated bluntly (en mass) from a fascicle near the proximal end of the muscle unit and all terminated intramuscularly. Five of these ended in a taper and one ended bluntly. Fibres coursed on average for 70% of the muscle unit length. Six fibres from a FG unit (total length 34.76 mm) ranged from 8.97 to 18.38 mm in length and averaged 15.32 \u00b13.75 mm. All originated bluntly and terminated intramuscularly; one of these ended in a taper and five ended bluntly. Fibres coursed on average for 44% of the muscle unit length. Because fibres of individual muscle units do not extend the whole muscle unit territory, the effective cross-sectional area changes along the motor unit length. These non-uniformities in the distribution of fibres within a muscle unit emphasize that the functional interactions within and between motor units are complex.<\/jats:p>","DOI":"10.1098\/rstb.1999.0443","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T23:55:21Z","timestamp":1027727721000},"page":"917-925","source":"Crossref","is-referenced-by-count":8,"title":["Neuromuscular organization of avian flight muscle: architecture of single muscle fibres in muscle units of the pectoralis (pars thoracicus) of pigeon (Columba livia)"],"prefix":"10.1098","volume":"354","author":[{"given":"A. J.","family":"Sokoloff","sequence":"first","affiliation":[{"name":"Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA"}]},{"suffix":"Jr","given":"G. 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Jr 1987 Structure and neural control of the pectoralis in pigeons: implications for \u00a3ight mechanics. Anat. Rec. 218 284^287.","DOI":"10.1002\/ar.1092180309"},{"key":"p_5","first-page":"16","article-title":"A functional analysis of the primary upstroke and downstroke muscles in the domestic pigeon (Columba livia) during \u00a3ight","volume":"134","author":"Dial K. P.","year":"1988","journal-title":"J. Exp. Biol."},{"key":"p_6","doi-asserted-by":"crossref","unstructured":"Eldred E. Ounjian M. Roy R. R. & Edgerton V. R. l993 Tapering of the intrafascicular endings of muscle \u00a2bers and its implications to relay of force. Anat. Rec. 263 390^398.","DOI":"10.1002\/ar.1092360213"},{"key":"p_7","doi-asserted-by":"crossref","unstructured":"English A. W. & Weeks O. I. 1984 Compartmentalization of single muscle units in cat lateral gastrocnemius. Exp. 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R. l987 Distribution and innervation of short interdigitated muscle \u00a2bers in parallel-\u00a2bered muscles of cat hindlimb. J. Morphol. 191 1^15.","DOI":"10.1002\/jmor.1051910102"},{"key":"p_14","unstructured":"Mayeda R. 1890 U ber die Kaliberverha ltnisse der quergestreiften Muskelfasern. Z. Biol. 27 119^152."},{"key":"p_15","doi-asserted-by":"crossref","unstructured":"Olson C. B. Carpenter D. O. & Henneman E. 1968 Orderly recruitment of muscle action potentials. Arch. Neurol. 19 591^597.","DOI":"10.1001\/archneur.1968.00480060061008"},{"key":"p_16","doi-asserted-by":"publisher","DOI":"10.1002\/neu.480220510"},{"key":"p_17","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.200.23.2987","article-title":"The contractile properties of the m. supracoracoideus in the pigeon and starling: a case for long-axis rotation of the humerus","volume":"200","author":"Poore S. O.","year":"1997","journal-title":"J. Exp. 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Mems Fell. R. Soc."],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>\n            <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"rsbm20210034f08.tif\" \/>\n          <\/jats:p>\n          <jats:p>John Conway was without doubt one of the most celebrated British mathematicians of the last half century. He first gained international recognition in 1968 when he constructed the automorphism group of the then recently-discovered Leech lattice, and in so doing discovered three new sporadic simple groups. At around the same time he invented The Game of Life, which brought him to the attention of a much wider audience and led to a cult following of Lifers. He also combined the methods of Cantor and Dedekind for extending number systems to construct what Donald Knuth (ForMemRS 2003) called \u2018surreal numbers\u2019, the achievement of which Conway was probably most proud. Throughout his life he continued to make significant contributions to many branches of mathematics, including number theory, logic, algebra, combinatorics and geometry, and in his later years he teamed up with Simon Kochen to produce the Free Will theorem, which asserts that if humans have free will then, in a certain sense, so do elementary particles. In this biographical memoir I attempt to give some idea of the depth and breadth of Conway's contribution to mathematics.<\/jats:p>","DOI":"10.1098\/rsbm.2021.0034","type":"journal-article","created":{"date-parts":[[2021,12,22]],"date-time":"2021-12-22T08:10:57Z","timestamp":1640160657000},"page":"117-138","update-policy":"http:\/\/dx.doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["John Horton Conway. 26 December 1937\u201411 April 2020"],"prefix":"10.1098","volume":"72","author":[{"given":"Robert Turner","family":"Curtis","sequence":"first","affiliation":[{"name":"School of Mathematics, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK"}]}],"member":"175","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"e_1_3_4_2_1","unstructured":"Benson D. 1980 The simple group J4 PhD thesis University of Cambridge."},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1090\/conm\/272\/04395"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.4007\/annals.2017.185.3.8"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0305004100052075"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01404633"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican1070-120"},{"key":"e_1_3_4_8_1","volume-title":"Polyominoes","author":"Golomb S. 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Soc. open sci."],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p>\n            This paper considers two models of ceramide-transfer protein (CERT)-mediated ceramide transfer at the\n            <jats:italic>trans<\/jats:italic>\n            -Golgi network proposed in the literature,\n            <jats:italic>short distance shuttle<\/jats:italic>\n            and\n            <jats:italic>neck swinging<\/jats:italic>\n            , and seeks\n            <jats:italic>structural<\/jats:italic>\n            (parameter-free) features of the two models, which rely exclusively on the peculiar interaction network and not on specific parameter values. In particular, it is shown that both models can be seen as flow-inducing systems, where the flows between pairs of species are tuned by the concentrations of other species, and suitable external inputs can\n            <jats:italic>structurally<\/jats:italic>\n            regulate ceramide transfer. In the short distance shuttle model, the amount of transferred ceramide is\n            <jats:italic>structurally<\/jats:italic>\n            tuned by active protein kinase D (PKD), both directly and indirectly, in a coherent feed-forward loop motif. In the neck-swinging model, the amount of transferred ceramide is\n            <jats:italic>structurally<\/jats:italic>\n            tuned by active PI4KIII\u03b2, while active PKD has an ambivalent effect, due to the presence of an incoherent feed-forward loop motif that directly inhibits ceramide transfer and indirectly promotes it; the\n            <jats:italic>structural<\/jats:italic>\n            role of active PKD is to favour CERT mobility in the cytosol. It is also shown that the influences among key variables often have\n            <jats:italic>structurally<\/jats:italic>\n            determined steady-state signs, which can help falsify the models against experimental traces.\n          <\/jats:p>","DOI":"10.1098\/rsos.180494","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T13:30:18Z","timestamp":1530106218000},"page":"180494","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Ceramide-transfer protein-mediated ceramide transfer is a structurally tunable flow-inducing mechanism with structural feed-forward loops"],"prefix":"10.1098","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8600-1738","authenticated-orcid":false,"given":"Giulia","family":"Giordano","sequence":"first","affiliation":[{"name":"Delft Center for Systems and Control, Delft University of Technology (TU Delft), 2628 CD Delft, The Netherlands"}]}],"member":"175","published-online":{"date-parts":[[2018,6,27]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004180050245"},{"key":"e_1_3_5_3_2","first-page":"3","article-title":"Intorno alla struttura delle cellule nervose","volume":"13","author":"Golgi C","year":"1898","journal-title":"Bollettino della Societ\u00e0 Medico-Chirurgica di Pavia"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature02188"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-211-76310-0"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9219.2004.00186.x"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.24.110707.175421"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.673582"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12423"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200105033"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2011.12.005"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2971"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2007.01.009"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2009.01.006"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M605032200"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2015.04.001"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600034"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2005.04.001"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R600021200"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M702423200"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2013.08.022"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1289"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-005-9044-z"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200709055"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.86.426"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M702291200"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.528380"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12918-015-0147-1"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2009.02.014"},{"key":"e_1_3_5_30_2","first-page":"2522","article-title":"Identification of novel CERT ligands as potential ceramide trafficking inhibitors","volume":"15","author":"Santos C","year":"2014","journal-title":"Chem. 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Although there had been political exclusions in 1952 any nation with scientific activities of any significance had been without question an adhering member with the national scientific organizations (in the UK this was the Royal Society) providing the financial support for the work of the international body."},{"key":"e_1_3_1_5_2","unstructured":"\u2018A steerable radio telescope\u2019 a collection of papers describing the proposal written by B. Lovell J. A. Clegg and J. G. Davies (the \u2018Blue Book\u2019) deposited in the University of Manchester John Rylands Library."},{"key":"e_1_3_1_6_2","unstructured":"Dr John P. Hagen the radio-physicist in the Naval Research Laboratory who was appointed director of the Vanguard project subsequently described some of the unbelievable difficulties that the project faced. The most revealing of these was that the Army turned down his request to be allowed to use its rocket testing pads at Cape Canaveral on the grounds that this would interfere with their missile test programme. The Vanguard team therefore had to build its own launch complex and blockhouse for which no funds had been provided. This construction work took one and a half years."},{"key":"e_1_3_1_7_2","unstructured":"James M. Gavin War and peace in the space age (Harper New York 1958)."},{"key":"e_1_3_1_8_2","unstructured":"See note 5."},{"key":"e_1_3_1_9_2","unstructured":"According to the New York Times of 27 August 1957 the text of Khrushchev's announcement was as follows: \u2018A super-long-distance intercontinental multi-stage ballistic missile was launched a few days ago. The tests of the rocket were successful. They fully confirmed the correctness of the calculations and the selected design. The missile flew at a very high unprecedented altitude. Covering a huge distance in a brief time the missile landed in the target area. The results obtained show that it is possible to direct missiles into any part of the world.\u2019."},{"key":"e_1_3_1_10_2","doi-asserted-by":"crossref","unstructured":"M. Ryle \u2018Observations at the Mullard Radio Astronomy Observatory Cambridge\u2019 Proc. R. Soc. A 248 3\u20139 (1958).","DOI":"10.1098\/rspa.1958.0215"},{"key":"e_1_3_1_11_2","doi-asserted-by":"crossref","unstructured":"F. G. Smith \u2018A new navigation system using artificial earth satellites\u2019 J. Inst. Navig. 13 109\u2013111 (1960).","DOI":"10.1017\/S0373463300037322"},{"key":"e_1_3_1_12_2","unstructured":"Lovell op. cit. (note 1) chs 26\u201331."},{"key":"e_1_3_1_13_2","doi-asserted-by":"crossref","unstructured":"Staff of Jodrell Bank \u2018Radio observations of the first Russian earth satellite and its carrier rocket\u2019 Nature 180 941\u2013942 (1957) and Proc. R. Soc. A 248 24\u201333 (1958).","DOI":"10.1038\/180941a0"},{"key":"e_1_3_1_14_2","unstructured":"Lovell op. cit. (note 1) ch. 32."},{"key":"e_1_3_1_15_2","doi-asserted-by":"crossref","unstructured":"J. G. Davies and B. Lovell \u2018Observations of the Russian moon rocket\u2014Lunik 2\u2019 Nature 184 501\u2013502 (1959).","DOI":"10.1038\/184501a0"},{"key":"e_1_3_1_16_2","unstructured":"Deposited in the University of Manchester John Rylands Library; see also Staff of Jodrell Bank op. cit. ( Proc. R. Soc. A note 12)."},{"key":"e_1_3_1_17_2","unstructured":"Air Vice Marshal Douglas Morris was Assistant Chief of Air Staff (Air Defence) from 1957 to 1959."},{"key":"#cr-split#-e_1_3_1_18_2.1","doi-asserted-by":"crossref","unstructured":"D. Barber H. K. Sutcliffe and C. D. Watkins 'Some radar observations of meteors and aurorae at 300 and 500\u200aMc\/s using a large radio telescope - I. Observations of meteors' J. Atmos. Terrest. Phys. 24 585-597 (1962)","DOI":"10.1016\/0021-9169(62)90081-8"},{"key":"#cr-split#-e_1_3_1_18_2.2","doi-asserted-by":"crossref","unstructured":"idem 'Some radar observations of meteors and aurorae at 300 and 500\u200aMc\/s using a large radio telescope - II. Observations of the Aurora Borealis' J. Atmos. Terrest. Phys. 24 599-607 (1962).","DOI":"10.1016\/0021-9169(62)90082-X"},{"key":"e_1_3_1_19_2","unstructured":"Air Marshal John G. Weston; from 1956 to 1959 he was Assistant Chief of the Air Staff (Signals)."},{"key":"e_1_3_1_20_2","doi-asserted-by":"crossref","unstructured":"Zuckerman (FRS 1943; then Sir Solly) was created a Life Peer in 1971. For an account of his distinguished career in zoology and defence see P. L. Krohn \u2018Solly Zuckerman Baron Zuckerman of Burnham Thorpe O.M. K.C.B.\u2019 Biogr. Mems Fell. R. Soc. 41 575\u2013598 (1995).","DOI":"10.1098\/rsbm.1995.0034"},{"key":"e_1_3_1_21_2","unstructured":"Sir Robert Cockburn; see also note 2."},{"key":"e_1_3_1_22_2","unstructured":"Air Chief Marshal Sir Edmund Huddleston was Vice Chief of Air Staff 1957\u201362."},{"key":"e_1_3_1_23_2","unstructured":"Sir Maurice Dean was Permanent Under Secretary of State Air Ministry 1955\u201363."},{"key":"e_1_3_1_24_2","doi-asserted-by":"crossref","unstructured":"L. R. Allen B. Anderson R. G. Conway H. P. Palmer V. C. Reddish and B. Rowson \u2018Observations of 384 radio sources at a frequency of 158\u200aMc\/s with a long baseline interferometer\u2019 Mon. Not. R. Astron. Soc. 124 477\u2013499 (1962) and L. R. Allen R. Hanbury Brown and H. P. Palmer \u2018An analysis of the angular sizes of radio sources\u2019 Mon. Not. R. Astron. 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Soc. open sci."],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Black\u2013Scholes (BS) is a remarkable quotation model for European option pricing in financial markets. Option prices are calculated using an analytical formula whose main inputs are strike (at which price to exercise) and volatility. The BS framework assumes that volatility remains constant across all strikes; however, in practice, it varies. How do traders come to learn these parameters? We introduce natural agent-based models, in which traders update their beliefs about the true implied volatility based on the opinions of other agents. We prove exponentially fast convergence of these opinion dynamics, using techniques from control theory and leader-follower models, thus providing a resolution between theory and market practices. 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Soc. open sci."],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>Being a fatal threat to life, the breakdown of homeostasis in tissues is believed to involve multiscale factors ranging from the accumulation of genetic damages to the deregulation of metabolic processes. Here, we present a prototypical multicellular homeostasis model in the form of a two-dimensional stochastic cellular automaton with three cellular states, cell division, cell death and cell cycle arrest, of which the state-updating rules are based on fundamental cell biology. Despite the simplicity, this model illustrates how multicellular organizations can develop into diverse homeostatic patterns with distinct morphologies, turnover rates and lifespans without considering genetic, metabolic or other exogenous variations. Through mean-field analysis and Monte\u2013Carlo simulations, those homeostatic states are found to be classified into extinctive, proliferative and degenerative phases, whereas healthy multicellular organizations evolve from proliferative to degenerative phases over a long time, undergoing a systematic ageing akin to a transition into an absorbing state in non-equilibrium physical systems. It is suggested that the collapse of homeostasis at the multicellular level may originate from the fundamental nature of cell biology regarding the physics of some non-equilibrium processes instead of subcellular details.<\/jats:p>","DOI":"10.1098\/rsos.190012","type":"journal-article","created":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T07:06:19Z","timestamp":1562742379000},"page":"190012","update-policy":"https:\/\/doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Homeostasis and systematic ageing as non-equilibrium phase transitions in computational multicellular organizations"],"prefix":"10.1098","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1634-1673","authenticated-orcid":true,"given":"Yuting","family":"Lou","sequence":"first","affiliation":[{"name":"SCS Laboratory, Department of Human and Environmental Engineering, Graduate School of Frontier Sciences, The University of Tokyo, 277-8561 Chiba, Japan"}]},{"given":"Ao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Physics, Fudan University, Shanghai, People\u2019s Republic of China"}]},{"given":"Erika","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Systems Innovation, Faculty of Engineering, The University of Tokyo, 111-8564 Tokyo, Japan"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"SCS Laboratory, Department of Human and Environmental Engineering, Graduate School of Frontier Sciences, The University of Tokyo, 277-8561 Chiba, Japan"}]}],"member":"175","published-online":{"date-parts":[[2019,7,10]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.10.004"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1235249"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1104815"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2017.06.005"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.089920"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.01.036"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1109\/MEMB.2009.931790"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7643-8123-3"},{"volume-title":"Numerical methods and advanced simulation in biomechanics and biological processes","year":"2017","author":"Cerrolaza M","key":"e_1_3_7_10_2"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-071811-150104"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1201\/b10407"},{"key":"e_1_3_7_13_2","first-page":"3","article-title":"Constraint based modeling going multicellular","volume":"3","author":"Conde M","year":"2016","journal-title":"Front. 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R. Soc. A."],"published-print":{"date-parts":[[2010,6,8]]},"abstract":"<jats:p>\n            A mathematical model of a unicycle and rider, with a uniquely realistic tyre force and moment representation, is set up with the aid of multibody modelling software. The rider\u2019s upper body is joined to the lower body through a spherical joint, so that wheel, yaw, pitch and roll torques are available for control. The rider\u2019s bandwidth is restricted by low-pass filters. The linear equations describing small perturbations from a straight-running state are shown, which equations derive from a parallel derivation yielding the same eigenvalues as obtained from the first method. A nonlinear simulation model and the linear model for small perturbations from a general trim (or dynamic equilibrium) state are constructed. The linear model is used to reveal the stability properties for the uncontrolled machine and rider near to straight running, and for the derivation of optimal controls. These controls minimize a cost function made up of tracking errors and control efforts. Optimal controls for near-straight-running conditions, with left\/right symmetry, and more complex ones for cornering trims are included. Frequency responses of some closed-loop systems, from the former class, demonstrate excellent path-tracking qualities within bandwidth and amplitude limits. Controls are installed for path-following trials. Lane-change and clothoid manoeuvres are simulated, demonstrating good-quality tracking of longitudinal and lateral demands. Pitch torque control is little used by the rider, while yaw and roll torques are complementary, with the former being more useful in transients, while the latter has value\u00a0also in steady states. Wheel torque is influential on lateral control in turning. Adaptive control by gain switching is used to enable clothoid tracking up to lateral accelerations greater than 1\u2009m\u2009s\n            <jats:sup>\u22122<\/jats:sup>\n            . 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This finding is further borne out by asymptotic analysis, which confirms that the limiting form of the far-field interaction depends solely upon the relative orientation between the microorganisms. Those which swim in the same general direction are seen to experience very large lateral displacements (many times the size of the displacements experienced owing to interactions between less well-aligned swimmers). This clearly has potential implications for very dilute suspensions in which squirmers become broadly aligned in their swimming direction (e.g. during chemotaxis). We show that hydrodynamically enhanced cell spreading, previously reported for denser suspensions, can persist even at extreme dilutions. 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R. Soc. B."],"published-print":{"date-parts":[[2005,10,22]]},"abstract":"<jats:p>How parthenogenetic lineages arise from sexual ancestors may strongly influence their persistence over evolutionary time. Hybrid parthenogens often have elevated heterozygosity and ploidy, thus making it difficult to disentangle the influence of reproductive mode, hybridity and ploidy on their relative fitness. By comparing the relative fitness of both hybrid and non-hybrid parthenogens to their sexual ancestors, further insight may be gained into how these three factors influence the maintenance of sexual and parthenogenetic reproduction. In the present study, hybrid and non-hybrid parthenogenetic and sexual snails (<jats:italic>Campeloma<\/jats:italic>sp.) were compared for the following characteristics: female size-fecundity curves, offspring size, survivorship, and growth. Compared to nearby sexual populations, triploid hybrid parthenogens from the Florida Gulf coast have similar fecundity and offspring size, five-times higher survivorship, and 60% higher growth. Relative to nearby sexual populations, non-hybrid parthenogenetic<jats:italic>C. limum<\/jats:italic>from the Atlantic coast have significantly higher fecundity, smaller offspring size, similar survivorship and slightly lower growth. Given the considerable fitness advantages of parthenogens, especially hybrid parthenogens, it is enigmatic as to why these parthenogens occupy marginal natural habitats.<\/jats:p>","DOI":"10.1098\/rspb.2005.3208","type":"journal-article","created":{"date-parts":[[2005,9,26]],"date-time":"2005-09-26T16:13:48Z","timestamp":1127751228000},"page":"2149-2153","source":"Crossref","is-referenced-by-count":8,"title":["Mode of origin differentially influences the fitness of parthenogenetic freshwater snails"],"prefix":"10.1098","volume":"272","author":[{"given":"Steven G","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, University of New OrleansNew Orleans, LA 70148, USA"}]}],"member":"175","published-online":{"date-parts":[[2005,9]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0014-3820.2003.tb01504.x"},{"key":"e_1_3_2_3_1","first-page":"603","article-title":"Intraspecific hybridization, developmental stability and fitness in Drosophila mercatorum","volume":"4","author":"Anderson D.H","year":"2002","journal-title":"Evol. 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A"],"published-print":{"date-parts":[[2018,1,13]]},"DOI":"10.1098\/rsta\/376\/2110","type":"journal-issue","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T09:12:01Z","timestamp":1511773921000},"source":"Crossref","is-referenced-by-count":0,"prefix":"10.1098","volume":"376","member":"175","published-online":{"date-parts":[[2017,11,27]]},"container-title":["Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences"],"deposited":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T09:12:01Z","timestamp":1511773921000},"score":0.0,"resource":{"primary":{"URL":"http:\/\/rsta.royalsocietypublishing.org\/content\/376\/2110"}},"issued":{"date-parts":[[2017,11,27]]},"references-count":0,"journal-issue":{"issue":"2110","published-online":{"date-parts":[[2017,11,27]]},"published-print":{"date-parts":[[2018,1,13]]}},"URL":"https:\/\/doi.org\/10.1098\/rsta\/376\/2110","ISSN":["1471-2962"],"issn-type":[{"value":"1471-2962","type":"electronic"}],"published":{"date-parts":[[2017,11,27]]}},{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T08:18:31Z","timestamp":1649146711002},"reference-count":9,"publisher":"The Royal Society","license":[{"start":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T00:00:00Z","timestamp":1504051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Biogr. Mems Fell. R. Soc."],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p>\n            <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"rsbm20170020f08.gif\" \/>\n          <\/jats:p>\n          <jats:p>John Cooper's innovative research into the genetics of plant growth and development was established with the aim of identifying characters which would guide plant breeders in their selection programmes. Working with certain forage grasses (mainly ryegrass but also cocksfoot and fescue), he analysed growth and development into components, including flowering time, leaf development, photosynthetic efficiency, canopy structure in the crop and nutritional quality. He and his colleagues were able to show, by a combination of selection experiments and comparisons of variance between and within families, that considerable genetic variation existed within all varieties of these outbreeding crops. All the characters were polygenic, with no evidence of individual genes manifesting distinct Mendelian ratios. Cooper obtained information of great value for the plant breeders with whom he worked closely. His research stimulated others to build on his ideas when new molecular techniques became available.<\/jats:p>\n          <jats:p>After two decades of creative research at the Welsh Plant Breeding Station, John Cooper became its Director in 1975. This coincided with a turbulent period in government-sponsored agricultural research that involved reductions in funding. Cooper disagreed with the underlying policy changes, but he worked hard to minimize the number of redundancies and the damage to the scientific work of the station. Overall, John Cooper had a distinguished scientific career. His personal achievements from his own research activities and that of his colleagues were unique and innovative. He led by example, by stimulation and by inspiration, and developed a wide international influence for his ideas.<\/jats:p>","DOI":"10.1098\/rsbm.2017.0020","type":"journal-article","created":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T09:10:23Z","timestamp":1504084223000},"page":"89-106","update-policy":"http:\/\/dx.doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["John Philip Cooper CBE. 16 December 1923\u201418 November 2011"],"prefix":"10.1098","volume":"64","author":[{"given":"Kenneth","family":"Edwards","sequence":"first","affiliation":[{"name":"10 Sedley Taylor Road, Cambridge CB2 8PW, UK"}]}],"member":"175","published-online":{"date-parts":[[2017,8,30]]},"reference":[{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1959.48"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aob.a083698"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.1963.32"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jxb\/20.1.170"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.1969.tb06467.x"},{"key":"e_1_3_5_8_2","first-page":"295","volume-title":"Potential crop production: a case study","author":"Breese E. L.","year":"1971"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1981.0038"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aob.a087797"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aob.a088117"}],"container-title":["Biographical Memoirs of Fellows of the Royal Society"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.2017.0020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/full-xml\/10.1098\/rsbm.2017.0020","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.2017.0020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T03:05:31Z","timestamp":1613358331000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsbm.2017.0020"}},"issued":{"date-parts":[[2017,8,30]]},"references-count":9,"alternative-id":["10.1098\/rsbm.2017.0020"],"URL":"https:\/\/doi.org\/10.1098\/rsbm.2017.0020","ISSN":["0080-4606","1748-8494"],"issn-type":[{"value":"0080-4606","type":"print"},{"value":"1748-8494","type":"electronic"}],"published":{"date-parts":[[2017,8,30]]},"assertion":[{"value":"2017-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]},{"indexed":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T03:04:49Z","timestamp":1649214289992},"reference-count":0,"publisher":"The Royal Society","issue":"1763","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences"],"published-print":{"date-parts":[[1999,12]]},"DOI":"10.1098\/rsta.1999.0490","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T23:55:21Z","timestamp":1027727721000},"page":"3205-3220","source":"Crossref","is-referenced-by-count":1,"title":["Engineering and the physical sciences: the EPSRC takes an informal look into the future"],"prefix":"10.1098","volume":"357","author":[{"given":"Nina","family":"Morgan","sequence":"first","affiliation":[{"name":"1Rose Cottage, East End, Chadlington, Oxon OX7 3LX, UK"}]},{"given":"J. M. T.","family":"Thompson","sequence":"additional","affiliation":[{"name":"2Centre for Nonlinear Dynamics, Civil Engineering Building, University College London, Gower Street, London WC1E 6BT, UK"}]}],"member":"175","published-online":{"date-parts":[[1999,12]]},"container-title":["Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsta.1999.0490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T10:34:16Z","timestamp":1563532456000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsta.1999.0490"}},"editor":[{"given":"J. M. T.","family":"Thompson","sequence":"additional","affiliation":[]}],"issued":{"date-parts":[[1999,12]]},"references-count":0,"journal-issue":{"issue":"1763","published-online":{"date-parts":[[1999,12]]},"published-print":{"date-parts":[[1999,12]]}},"alternative-id":["10.1098\/rsta.1999.0490"],"URL":"https:\/\/doi.org\/10.1098\/rsta.1999.0490","ISSN":["1364-503X","1471-2962"],"issn-type":[{"value":"1364-503X","type":"print"},{"value":"1471-2962","type":"electronic"}],"published":{"date-parts":[[1999,12]]}},{"indexed":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:22:36Z","timestamp":1720052556436},"reference-count":0,"publisher":"The Royal Society","content-domain":{"domain":[]},"published-print":{"date-parts":[[2024,3,18]]},"DOI":"10.1098\/rsbl.2024.0106\/v1\/review1","type":"peer-review","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:10:21Z","timestamp":1719994221000},"source":"Crossref","is-referenced-by-count":0,"title":["Review for \"Earliest evidence of avian primary feather moult\""],"prefix":"10.1098","author":[{"given":"Stephen","family":"Brusatte","sequence":"first","affiliation":[]}],"member":"175","review":{"type":"referee-report","running-number":"PR1V1","revision-round":"1","stage":"pre-publication"},"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:10:34Z","timestamp":1719994234000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/www.webofscience.com\/api\/gateway\/wos\/peer-review\/10.1098\/RSBL.2024.0106"}},"issued":{"date-parts":[[2024,3,18]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1098\/rsbl.2024.0106\/v1\/review1","relation":{"is-review-of":[{"id-type":"doi","id":"10.1098\/RSBL.2024.0106","asserted-by":"subject"}]},"published":{"date-parts":[[2024,3,18]]}},{"indexed":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:23:14Z","timestamp":1720052594558},"reference-count":0,"publisher":"The Royal Society","content-domain":{"domain":[]},"published-print":{"date-parts":[[2024,4,29]]},"DOI":"10.1098\/rsbl.2024.0171\/v1\/decision1","type":"peer-review","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:08:09Z","timestamp":1719994089000},"source":"Crossref","is-referenced-by-count":0,"title":["Decision letter for \"Decoupled evolution of ventral and dorsal scales in agamid lizards: ventral keels are associated with arboreality\""],"prefix":"10.1098","member":"175","review":{"type":"editor-report","running-number":"E1V1","revision-round":"1","stage":"pre-publication"},"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:08:22Z","timestamp":1719994102000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/www.webofscience.com\/api\/gateway\/wos\/peer-review\/10.1098\/RSBL.2024.0171"}},"editor":[{"family":"Rodney Honeycutt","sequence":"first","affiliation":[]}],"issued":{"date-parts":[[2024,4,29]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1098\/rsbl.2024.0171\/v1\/decision1","relation":{"is-review-of":[{"id-type":"doi","id":"10.1098\/RSBL.2024.0171","asserted-by":"subject"}]},"published":{"date-parts":[[2024,4,29]]}},{"indexed":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T00:20:55Z","timestamp":1720052455727},"reference-count":0,"publisher":"The Royal Society","content-domain":{"domain":[]},"published-print":{"date-parts":[[2024,2,22]]},"DOI":"10.1098\/rsos.231764\/v2\/decision1","type":"peer-review","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:16:24Z","timestamp":1719994584000},"source":"Crossref","is-referenced-by-count":0,"title":["Decision letter for \"Disentangling the seasonality effects of malaria transmission in the Brazilian Amazon basin\""],"prefix":"10.1098","member":"175","review":{"type":"editor-report","running-number":"E1V2","revision-round":"2","stage":"pre-publication"},"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T08:16:37Z","timestamp":1719994597000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/www.webofscience.com\/api\/gateway\/wos\/peer-review\/10.1098\/RSOS.231764"}},"editor":[{"family":"Mark Chaplain","sequence":"first","affiliation":[]}],"issued":{"date-parts":[[2024,2,22]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1098\/rsos.231764\/v2\/decision1","relation":{"is-review-of":[{"id-type":"doi","id":"10.1098\/RSOS.231764","asserted-by":"subject"}]},"published":{"date-parts":[[2024,2,22]]}},{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T21:42:46Z","timestamp":1649022166715},"reference-count":0,"publisher":"The Royal Society","license":[{"start":{"date-parts":[[1792,12,31]],"date-time":"1792-12-31T00:00:00Z","timestamp":-5585587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phil. Trans. R. Soc."],"published-print":{"date-parts":[[1792,12,31]]},"abstract":"<jats:p>\n            Sir, I Take the liberty of sending you two or three pieces of a bird whose substance has been converted into a hard fatty matter, which I found at the head of a fish pool, where a small brook runs into it, lying under water upon the mud. When first taken out, it was almost entire, and had several feathers sticking in different parts of the skin, which have since fallen out; a little down, however, still adheres to the smaller specimen. From the size, and general appearance of the bird, I conjectured it to be a duck, or young goose; but before I had time to give it a particular examination, it was unfortunately broken in pieces, and the greatest part destroyed. The skin in the piece which was saved is of different thicknesses, in some parts a full quarter of an inch; it has retained its original structure exactly, but is in great part separated from the flesh, though both of them are now composed of the same fat matter. This substance resembles spermaceti in its consistence' between the teeth, but has neither taste nor smell; it melts in a small heat, and when congealed again, becomes more solid, and looks like wax; in a greater heat it burns, and emits a strong animal smell. As I never heard or perceived that the water in which this bird lay has any particular property, I am inclined to think that it has undergone this singular change while buried in the mud, and that the brook had afterwards washed it up, and carried it into this pool. I am sorry that the specimen and my account of this singular metamorphosis are so imperfect. The analogy which the case bears to the change of human bodies, observed by M. Fourcroy * in the Cemetery\n            <jats:italic>des Innocents<\/jats:italic>\n            , is my chief reason for offering them to you; and if they should be deemed worthy of the notice of the illustrious Society over which you preside, you are at liberty to present them.\n          <\/jats:p>","DOI":"10.1098\/rstl.1792.0013","type":"journal-article","created":{"date-parts":[[2006,12,15]],"date-time":"2006-12-15T22:28:29Z","timestamp":1166221709000},"page":"197-198","source":"Crossref","is-referenced-by-count":0,"title":["IX. On the conversion of the substance of a bird into a hard fatty matter. In a letter from Thomas Sneyd, Esq. to Sir Joseph Banks, Bart. P. R. S"],"prefix":"10.1098","volume":"82","member":"175","published-online":{"date-parts":[[1997,1]]},"container-title":["Philosophical Transactions of the Royal Society of London"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstl.1792.0013","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rstl.1792.0013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T17:00:04Z","timestamp":1613667604000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rstl.1792.0013"}},"issued":{"date-parts":[[1792,12,31]]},"references-count":0,"alternative-id":["10.1098\/rstl.1792.0013"],"URL":"https:\/\/doi.org\/10.1098\/rstl.1792.0013","ISSN":["0261-0523","2053-9223"],"issn-type":[{"value":"0261-0523","type":"print"},{"value":"2053-9223","type":"electronic"}],"published":{"date-parts":[[1792,12,31]]}},{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T05:04:01Z","timestamp":1648875841419},"reference-count":9,"publisher":"The Royal Society","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biogr. Mems Fell. R. Soc."],"published-print":{"date-parts":[[2000,1]]},"abstract":"<jats:p>There could be no better words with which to open an account of John (Jack) Heslop\u2013Harrison's life than his own advice to students: \u2018He who makes botany his life's work has many satisfactions before him; not least the sheer pleasure of investigating and handling entities so intrinsically beautiful and perfect at all levels of organization as plants\u2019 (1).*<\/jats:p>","DOI":"10.1098\/rsbm.1999.0080","type":"journal-article","created":{"date-parts":[[2006,12,15]],"date-time":"2006-12-15T23:02:19Z","timestamp":1166223739000},"page":"197-217","source":"Crossref","is-referenced-by-count":1,"title":["John Heslop-Harrison. 10 February 1920 \u2013 7 May 1998"],"prefix":"10.1098","volume":"46","author":[{"given":"Brian E.S.","family":"Gunning","sequence":"first","affiliation":[{"name":"Plant Cell Biology Group, Research School of Biological SciencesPO Box 475, Canberra, ACT 2605Australia"}]}],"member":"175","published-online":{"date-parts":[[2000,11]]},"reference":[{"key":"p_1","unstructured":"Quotations in the text are from the following publications. A full bibliography appears on the"},{"key":"p_2","unstructured":"accompanying microfiche numbered as in the second column. A photocopy is available from"},{"key":"p_3","unstructured":"The Royal Society's Library at cost. Autobiographical papers on `Origins and ancestry' and"},{"key":"p_4","unstructured":"`War service' can be read at Professor J.S. Heslop-Harrison's Web site along with extended"},{"key":"p_5","unstructured":"biographical material compiled by B. Gunning from documents and summaries provided by"},{"key":"p_6","unstructured":"Y. Heslop-Harrison."},{"key":"p_7","unstructured":"(102) 1966 Botany as a university subject. In University choice (ed. K. Boehm) pp. 61-75."},{"key":"p_8","unstructured":"Harmondsworth: Penguin Books."},{"key":"p_9","volume":"4","author":"The","unstructured":"(159) 1972 The prospect ahead. J. Kew Guild , 4 4-51.","journal-title":"J. Kew Guild"}],"container-title":["Biographical Memoirs of Fellows of the Royal Society"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.1999.0080","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.1999.0080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T16:30:53Z","timestamp":1622824253000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsbm.1999.0080"}},"subtitle":["Elected F.R.S. 1970"],"issued":{"date-parts":[[2000,1]]},"references-count":9,"alternative-id":["10.1098\/rsbm.1999.0080"],"URL":"https:\/\/doi.org\/10.1098\/rsbm.1999.0080","ISSN":["0080-4606","1748-8494"],"issn-type":[{"value":"0080-4606","type":"print"},{"value":"1748-8494","type":"electronic"}],"published":{"date-parts":[[2000,1]]}},{"indexed":{"date-parts":[[2022,4,6]],"date-time":"2022-04-06T03:38:32Z","timestamp":1649216312159},"reference-count":16,"publisher":"The Royal Society","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biogr. Mems Fell. R. Soc."],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>\n            George Francis Mitchell, Frank to all who knew him, died peacefully at the age of 85 in October 1997 after a short illness. He was the son of David William Mitchell and Frances Elizabeth Mitchell (\n            <jats:italic>n\u00e9e Kirby<\/jats:italic>\n            ), and had led an extraordinarily distinguished, productive and varied life. The Mitchells were a family of Scottish origin who came to Dublin in the mid-nineteenth century. They were in a variety of businesses, from upholstery for railway carriages to fine fabrics, from furniture and hardware to laboratory suppliers of glassware and chemicals. Frank and his brother David, a consultant physician, and his sister Lillias, who maintained a family tradition as a teacher of fine textiles, were the first generation of the family to experience third-level education.\n          <\/jats:p>","DOI":"10.1098\/rsbm.1999.0021","type":"journal-article","created":{"date-parts":[[2006,12,15]],"date-time":"2006-12-15T19:35:25Z","timestamp":1166211325000},"page":"315-328","source":"Crossref","is-referenced-by-count":0,"title":["George Francis Mitchell. 15 October 1912 \u2014 25 November 1997"],"prefix":"10.1098","volume":"45","author":[{"given":"W.A.","family":"Watts","sequence":"first","affiliation":[{"name":"Department of Botany, Trinity CollegeDublin 2Ireland"}]},{"given":"R.G.","family":"West","sequence":"additional","affiliation":[{"name":"Botany School, University of CambridgeDowning Street, Cambridge CB2 3EAUK"}]}],"member":"175","published-online":{"date-parts":[[1999,11]]},"reference":[{"key":"p_1","unstructured":"The following publications are those referred to directly in the text. A full bibliography"},{"key":"p_2","unstructured":"appears on the accompanying microfiche numbered as in the second column. A copy is"},{"key":"p_3","unstructured":"available from the Royal Society Library at cost."},{"key":"p_4","first-page":"185","article-title":"Post-Boreal pollen-diagrams from Irish raised bogs","volume":"57","year":"1956","journal-title":"Proc. R. Irish Acad. B"},{"key":"p_5","first-page":"121","article-title":"Littleton Bog, Tipperary: an Irish agricultural record","volume":"95","year":"1965","journal-title":"J. R. Soc. Antiq. Ireland"},{"key":"p_6","unstructured":"."},{"key":"p_7","unstructured":"(86) 1973 (With L.F. Penny F.W. Shotton and R.G. West) A correlation of Quaternary deposits in"},{"key":"p_8","unstructured":"the British Isles. Geol. Soc. Lond. Spec. Rep. 4 1-99."},{"key":"p_9","unstructured":"(136) 1976 The Irish landscape. London: Collins. (240 pages.)"},{"key":"p_10","unstructured":"(137) 1977 (Ed. with L. Boltin) Treasures of early Irish art: 1500 B.C.-1500 A.D. New York:"},{"key":"p_11","unstructured":"Metropolitan Museum of Art. (221 pages.)"},{"key":"p_12","unstructured":"(138) 1985 (With B. Tuite) The Great Bog of Ardee. Dundalk: County Louth Archaeological and"},{"key":"p_13","unstructured":"Historical Society. (95 pages.)"},{"key":"p_14","unstructured":"(140) 1989 Man and environment on Valencia Island. Dublin: Royal Irish Academy. (130 pages.)"},{"key":"p_15","unstructured":"(141) 1990 The way that I followed. Dublin: Country House. (271 pages.)"},{"key":"p_16","unstructured":"(143) 1997 (With M. Ryan) Reading the Irish landscape. Dublin: Town House. (392 pages.)"}],"container-title":["Biographical Memoirs of Fellows of the Royal Society"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.1999.0021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsbm.1999.0021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T00:10:03Z","timestamp":1613347803000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsbm.1999.0021"}},"subtitle":["Elected F.R.S. 1973"],"issued":{"date-parts":[[1999,1]]},"references-count":16,"alternative-id":["10.1098\/rsbm.1999.0021"],"URL":"https:\/\/doi.org\/10.1098\/rsbm.1999.0021","ISSN":["0080-4606","1748-8494"],"issn-type":[{"value":"0080-4606","type":"print"},{"value":"1748-8494","type":"electronic"}],"published":{"date-parts":[[1999,1]]}},{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T20:38:09Z","timestamp":1649191089843},"reference-count":50,"publisher":"The Royal Society","license":[{"start":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:00:00Z","timestamp":1616544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/royalsociety.org\/journals\/ethics-policies\/data-sharing-mining\/"}],"content-domain":{"domain":["royalsocietypublishing.org"],"crossmark-restriction":true},"short-container-title":["Biogr. Mems Fell. R. Soc."],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>\n            <jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"rsbm20200040f10.tif\" \/>\n          <\/jats:p>\n          <jats:p>Professor Tom Kibble was an internationally-renowned theoretical physicist whose contributions to theoretical physics range from the theory of elementary particles to modern early-Universe cosmology. The unifying theme behind all his work is the theory of non-abelian gauge theories, the Yang\u2013Mills extension of electromagnetism. One of Kibble's most important pieces of work in this area was his study of the symmetry-breaking mechanism whereby the force-carrying vector particles in the theory can acquire a mass accompanied by the appearance of a massive scalar boson. This idea, put forward independently by Brout and Englert, by Higgs, and by Guralnik, Hagen and Kibble in 1964, and generalized by Kibble in 1967, lies at the heart of the Standard Model and all modern unified theories of fundamental particles. It was vindicated in 2012 by the discovery of the Higgs boson at CERN. According to Nobel Laureate Steven Weinberg: \u2018Tom Kibble showed us why light is massless\u2019; this is the fundamental basis of electromagnetism.<\/jats:p>","DOI":"10.1098\/rsbm.2020.0040","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T00:07:22Z","timestamp":1616544442000},"page":"225-244","update-policy":"http:\/\/dx.doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Sir Thomas Walter Bannerman Kibble. 23 December 1932\u20142 June 2016"],"prefix":"10.1098","volume":"70","author":[{"given":"M. J.","family":"Duff","sequence":"first","affiliation":[{"name":"The Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2BW, UK"}]},{"given":"K. S.","family":"Stelle","sequence":"additional","affiliation":[{"name":"The Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2BW, UK"}]}],"member":"175","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRev.130.439"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.13.321"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1088\/1126-6708\/2004\/06\/013"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0370-1573(95)00002-X"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-5582(61)90469-2"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRev.127.965"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevD.101.105001"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9163(64)91136-9"},{"key":"e_1_3_3_10_1","unstructured":"Nambu Y. 1960 Dynamical theory of elementary particles suggested by superconductivity. 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R. Soc. Lond."],"published-print":{"date-parts":[[1998,7,22]]},"abstract":"<jats:p>Arthur Cayley, F.R.S. (1821\u20131895) is widely regarded as Britain's leading pure mathematician of the 19th century. From his start as a Cambridge prodigy, he built up a formidable record of publication, from incidental notes to extensive memoirs, on a wide range of mathematics. His emergence as a mathematician, before he became the sober\u2013minded eminence of the 1860s and 1870s, is largely unknown. The primary guide to his whole life remains, more than a century later, the obituary written by his student and successor at Cambridge, A.R. Forsyth. The folklore surrounding Cayley's life is dominated by his collaboration with James Joseph Sylvester, F.R.S. (1814\u20131897). This partnership, tempered by Sylvester's obsession with the apportionment of credit, began in earnest in the 1850s. In this paper, I attempt to signpost Cayley's formative years, when he was at the beginning of his long mathematical journey, the period which ends on 3 June 1852, the date of his election to the Royal Society, when he formally came of age as a Victorian man of science.<\/jats:p>","DOI":"10.1098\/rsnr.1998.0050","type":"journal-article","created":{"date-parts":[[2004,5,14]],"date-time":"2004-05-14T14:18:24Z","timestamp":1084544304000},"page":"267-282","source":"Crossref","is-referenced-by-count":2,"title":["The young Arthur Cayley"],"prefix":"10.1098","volume":"52","author":[{"given":"T.","family":"Crilly","sequence":"first","affiliation":[{"name":"Middlesex University Business School, The Burroughs, London NW4 4BT, UK ()"}]}],"member":"175","published-online":{"date-parts":[[1998,7,22]]},"container-title":["Notes and Records of the Royal Society of London"],"language":"en","link":[{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsnr.1998.0050","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/royalsocietypublishing.org\/doi\/pdf\/10.1098\/rsnr.1998.0050","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T20:05:37Z","timestamp":1613851537000},"score":0.0,"resource":{"primary":{"URL":"https:\/\/royalsocietypublishing.org\/doi\/10.1098\/rsnr.1998.0050"}},"issued":{"date-parts":[[1998,7,22]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,7,22]]}},"alternative-id":["10.1098\/rsnr.1998.0050"],"URL":"https:\/\/doi.org\/10.1098\/rsnr.1998.0050","ISSN":["0035-9149"],"issn-type":[{"value":"0035-9149","type":"print"}],"published":{"date-parts":[[1998,7,22]]}},{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T09:11:14Z","timestamp":1648545074881},"reference-count":0,"publisher":"The Royal Society","issue":"2146","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Phil. 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This has led to large international programmes, some promising and others alarming, with laws about DNA patenting and ethical guidelines for responsible research still struggling to be born.<\/jats:p>","DOI":"10.1098\/rstb.2003.1357","type":"journal-article","created":{"date-parts":[[2003,10,15]],"date-time":"2003-10-15T20:01:10Z","timestamp":1066248070000},"page":"1701-1708","source":"Crossref","is-referenced-by-count":4,"title":["Genetic epidemiology, genetic maps and positional cloning"],"prefix":"10.1098","volume":"358","author":[{"given":"Newton E.","family":"Morton","sequence":"first","affiliation":[{"name":"University of Southampton, Human Genetics Division, Duthie Building, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK ()"}]}],"member":"175","published-online":{"date-parts":[[2003,8,13]]},"reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1038\/35084335"},{"key":"p_2","unstructured":"Agresti A. 1990 Categorical data analysis. 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We found that high structural quality and carotenoid chroma of juvenile feathers were positively linked to the extent of post-juvenile moult in this species, thus allowing young birds to attain more adult-like plumage. Silver spoon effects mediated by the juvenile plumage quality were also found to have other fitness-related consequences, as individuals with high-quality juvenile feathers were in better condition during their first winter. 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Mems Fell. R. Soc."],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p><jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"rsbm20190028f05.tif\" \/><\/jats:p><jats:p>John Newsom-Davis (\u2018JND\u2019) was a neurologist who played an important role in the discovery of the causes of, and treatments for, myasthenia gravis (MG), and of other diseases of the nerve\u2013muscle junction. He started his career at the National Hospital in London, becoming director of the Batten Unit there, with an interest in respiratory physiology. He began to work on MG in collaboration with Ricardo Miledi (FRS 1970) at University College London and in 1978, after performing the first study on plasma exchange in that disease, he established an MG research group at the Royal Free Hospital, subsequently identifying the role of the thymus in this disease and demonstrating an autoimmune basis for the Lambert\u2013Eaton myasthenic syndrome and \u2018seronegative\u2019 myasthenia. He was awarded the first Medical Research Council Clinical Research Professorship in 1979 but moved to Oxford in 1987 when he was elected Action Research Professor of Neurology. While at Oxford he continued to run a very successful multidisciplinary group, and began the molecular work that identified the genetic basis for many forms of congenital myasthenic syndrome. He also helped to establish the Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre. Meanwhile he was also involved in university and college governance and contributed widely to the Medical Research Council, government committees, and the Association of British Neurologists (ABN). Among many honours, he was appointed Commander of the Order of the British Empire in 1996 and made a Foreign Associate Member of the Institute of Medicine (now the National Academy of Medicine) in the USA in 2001. Following retirement from Oxford, he was President of the ABN and Editor of<jats:italic>Brain<\/jats:italic>, and led a National Institutes of Health-funded international trial of thymectomy.<\/jats:p>","DOI":"10.1098\/rsbm.2019.0028","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T07:05:37Z","timestamp":1566975937000},"page":"327-355","update-policy":"http:\/\/dx.doi.org\/10.1098\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["John Newsom-Davis. 18 October 1932\u201424 August 2007"],"prefix":"10.1098","volume":"67","author":[{"given":"Angela","family":"Vincent","sequence":"first","affiliation":[{"name":"Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford OX3 9DU, UK"}]}],"member":"175","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq230"},{"key":"e_1_3_4_3_1","first-page":"241","article-title":"Isolation of neurotoxins from the venom of Bungarus multicinctus and their modes of neuromuscular blocking actions","volume":"144","author":"Chang C. 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