{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:51:58Z","timestamp":1767963118829,"version":"3.49.0"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"37","funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council Taiwan","doi-asserted-by":"publisher","award":["100-2113-M-001-031-MY2"],"award-info":[{"award-number":["100-2113-M-001-031-MY2"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council Taiwan","doi-asserted-by":"publisher","award":["101-2627-M-001-004"],"award-info":[{"award-number":["101-2627-M-001-004"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000391","name":"Association for International Cancer Research","doi-asserted-by":"publisher","award":["10-0570"],"award-info":[{"award-number":["10-0570"]}],"id":[{"id":"10.13039\/501100000391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000854","name":"Human Frontier Science Program","doi-asserted-by":"publisher","award":["CDA\u201400025\/2010-C"],"award-info":[{"award-number":["CDA\u201400025\/2010-C"]}],"id":[{"id":"10.13039\/501100000854","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2014,9,23]]},"DOI":"10.1021\/bi500470b","type":"journal-article","created":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T11:22:47Z","timestamp":1408965767000},"page":"5848-5863","source":"Crossref","is-referenced-by-count":19,"title":["Nucleotide Contributions to the Structural Integrity and DNA Replication Initiation Activity of Noncoding Y RNA"],"prefix":"10.1021","volume":"53","author":[{"given":"Iren","family":"Wang","sequence":"first","affiliation":[{"name":"Institute\rof Biological Chemistry, Academia Sinica, 128, Section 2, Academia Road, Taipei 11529, Taiwan"}]},{"given":"Madzia P.","family":"Kowalski","sequence":"additional","affiliation":[{"name":"Department\rof Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom"}]},{"given":"Alexander R.","family":"Langley","sequence":"additional","affiliation":[{"name":"Department\rof Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom"}]},{"given":"Rapha\u00ebl","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom"}]},{"given":"Shankar","family":"Balasubramanian","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom"},{"name":"Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, United Kingdom"}]},{"given":"Shang-Te Danny","family":"Hsu","sequence":"additional","affiliation":[{"name":"Institute\rof Biological Chemistry, Academia Sinica, 128, Section 2, Academia Road, Taipei 11529, Taiwan"},{"name":"Department\rof Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom"},{"name":"Institute\rof Biochemical Sciences, National Taiwan University, 1, Section\r4, Roosevelt Road, Taipei 10617, Taiwan"},{"name":"Institute\rof Bioinformatics and Structural Biology, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan"}]},{"given":"Torsten","family":"Krude","sequence":"additional","affiliation":[{"name":"Department\rof Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, United Kingdom"}]}],"member":"316","published-online":{"date-parts":[[2014,9,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s12064-007-0003-y","volume":"129","author":"Mosig A.","year":"2007","journal-title":"Theory Biosci."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1093\/molbev\/msm084","volume":"24","author":"Perreault J.","year":"2007","journal-title":"Mol. Biol. Evol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/wrna.85","volume":"2","author":"Sim S.","year":"2011","journal-title":"Wiley Interdiscip. Rev.: RNA"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1002\/bies.201100048","volume":"33","author":"Verhagen A. P.","year":"2011","journal-title":"BioEssays"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/978-90-481-3471-7_6","volume":"50","author":"Krude T.","year":"2010","journal-title":"Subcell. Biochem."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1515\/bmc-2012-0050","volume":"4","author":"Hall A. E.","year":"2013","journal-title":"Biomol. Concepts"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1126\/science.6164096","volume":"211","author":"Lerner M. R.","year":"1981","journal-title":"Science"},{"key":"ref8\/cit8","first-page":"1138","volume":"1","author":"Hendrick J. P.","year":"1981","journal-title":"Mol. Cell. Biol."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.cell.2013.02.037","volume":"153","author":"Chen X.","year":"2013","journal-title":"Cell"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"6993","DOI":"10.1128\/MCB.01060-06","volume":"26","author":"Christov C. P.","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1038\/sj.bjc.6604254","volume":"98","author":"Christov C. P.","year":"2008","journal-title":"Br. J. Cancer"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1242\/jcs.047563","volume":"122","author":"Krude T.","year":"2009","journal-title":"J. Cell Sci."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1261\/rna.1472009","volume":"15","author":"Gardiner T. J.","year":"2009","journal-title":"RNA"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"e13673","DOI":"10.1371\/journal.pone.0013673","volume":"5","author":"Langley A. R.","year":"2010","journal-title":"PLoS One"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"13699","DOI":"10.1074\/jbc.275.18.13699","volume":"275","author":"Krude T.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"3857","DOI":"10.1128\/MCB.05411-11","volume":"31","author":"Collart C.","year":"2011","journal-title":"Mol. Cell. Biol."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1093\/nar\/22.13.2498","volume":"22","author":"van Gelder C. W.","year":"1994","journal-title":"Nucleic Acids Res."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1093\/nar\/28.2.610","volume":"28","author":"Teunissen S. W.","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1073\/pnas.81.7.1996","volume":"81","author":"Wolin S. L.","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1017\/S1355838298971667","volume":"4","author":"Green C. D.","year":"1998","journal-title":"RNA"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","unstructured":"W\u00fcthrich, K. (1986) NMR of Proteins and Nucleic Acids, p320,Wiley,New York.","DOI":"10.1051\/epn\/19861701011"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1002\/cbic.200300700","volume":"4","author":"Furtig B.","year":"2003","journal-title":"ChemBioChem"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1023\/A:1008276004875","volume":"11","author":"Hwang T. L.","year":"1998","journal-title":"J. Biomol. NMR"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"6203","DOI":"10.1021\/ja970160j","volume":"119","author":"Hwang T. L.","year":"1997","journal-title":"J. Am. Chem. Soc."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1093\/nar\/gkg595","volume":"31","author":"Zuker M.","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1006\/jmbi.1999.2700","volume":"288","author":"Mathews D. H.","year":"1999","journal-title":"J. Mol. Biol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1101\/gr.849004","volume":"14","author":"Crooks G. E.","year":"2004","journal-title":"Genome Res."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1006\/excr.1998.4342","volume":"247","author":"Krude T.","year":"1999","journal-title":"Exp. Cell Res."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.yexcr.2005.09.009","volume":"311","author":"Sz\u00fcts D.","year":"2005","journal-title":"Exp. Cell Res."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/nar\/gkg269","volume":"31","author":"Sz\u00fcts D.","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1242\/jcs.086561","volume":"124","author":"Zhang A. T.","year":"2011","journal-title":"J. Cell Sci."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"8293","DOI":"10.1021\/ja981513x","volume":"120","author":"Dingley A. J.","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"ref33\/cit33","first-page":"355","volume":"65","author":"Bax A.","year":"1985","journal-title":"J. Magn. Reson."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1093\/nar\/28.6.1322","volume":"28","author":"Hsu S. T.","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1006\/jmbi.1999.3388","volume":"295","author":"Hsu S. T.","year":"2000","journal-title":"J. Mol. Biol."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","volume":"6","author":"Delaglio F.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"W43","DOI":"10.1093\/nar\/gkm234","volume":"35","author":"Kibbe W. A.","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"12640","DOI":"10.1021\/bi0501885","volume":"44","author":"Hecky J.","year":"2005","journal-title":"Biochemistry"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.abb.2012.10.014","volume":"531","author":"Sancho J.","year":"2013","journal-title":"Arch. Biochem. Biophys."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1093\/nar\/gkp026","volume":"37","author":"Kypr J.","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"3967","DOI":"10.1093\/nar\/gkh723","volume":"32","author":"Mikulecky P. J.","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"19863","DOI":"10.1074\/jbc.272.32.19863","volume":"272","author":"Baumann C.","year":"1997","journal-title":"J. Biol. Chem."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"9734","DOI":"10.1073\/pnas.89.20.9734","volume":"89","author":"Loret E. P.","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"20711","DOI":"10.1074\/jbc.M101360200","volume":"276","author":"Fabini G.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0022-2836(02)00518-1","volume":"320","author":"Fouraux M. A.","year":"2002","journal-title":"J. Mol. Biol."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1146\/annurev.biochem.67.1.181","volume":"67","author":"Roberts R. J.","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","unstructured":"Cheng, X. and Roberts, R. J. (2010) Base flipping, pp1\u20138,John Wiley & Sons,Chichester, U.K.","DOI":"10.1002\/9780470015902.a0002714.pub2"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"E3295","DOI":"10.1073\/pnas.1212548109","volume":"109","author":"Kuttan A.","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi500470b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T15:32:20Z","timestamp":1681659140000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi500470b"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,5]]},"references-count":48,"journal-issue":{"issue":"37","published-print":{"date-parts":[[2014,9,23]]}},"alternative-id":["10.1021\/bi500470b"],"URL":"https:\/\/doi.org\/10.1021\/bi500470b","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,5]]}}}