{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T05:37:49Z","timestamp":1777873069562,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Facial Plast Surg"],"published-print":{"date-parts":[[2003,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the efficacy of decellularized dermal grafting used as an adjunct to the performance of primary repair of wide cleft palates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective review.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary referral center for large managed care organization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seven consecutive patients with clefts of the hard and soft palates wider than 15 mm as measured at the posterior edge of the hard palate. Palates were repaired in the standard 2-flap approach with intravelar veloplasty. The decellularized dermal graft (AlloDerm) was applied immediately deep to the oral mucosal closure. Patients were followed up with serial postoperative examination. Palates were assessed for dehiscence, fistula, infection, rejection, scarring, and contracture.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no fistulas. In 2 patients, the oral mucosa dehisced, exposing the dermal graft. In 2 other cases, nasal mucosal tears were inadvertently created during closure of the nasal layer. In all cases, the decellularized dermal graft mucosalized and, by clinical examination, became incorporated into the wound. There were no cases of local inflammation or infection. The degree of scarring and contracture was indistinguishable from the adjacent scar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Decellularized dermal graft is safe and effective for use in primary closure of wide clefts involving the hard and soft palates. Its application to wide clefts otherwise at risk of fistula is justified. Its use in repair of an existing fistula is also promising.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/archfaci.5.1.40","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T19:08:11Z","timestamp":1267470491000},"page":"40-44","source":"Crossref","is-referenced-by-count":76,"title":["Decellularized Dermal Grafting in Cleft Palate Repair"],"prefix":"10.1177","volume":"5","author":[{"given":"J. Madison","family":"Clark","sequence":"first","affiliation":[{"name":"From the Department of Otolaryngology, Head and Neck Surgery, Oregon Health Sciences University, Portland (Drs Clark and Saffold), and Kaiser Permanente Health Care Systems, Clackamas, Ore (Dr Israel)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott H.","family":"Saffold","sequence":"additional","affiliation":[{"name":"From the Department of Otolaryngology, Head and Neck Surgery, Oregon Health Sciences University, Portland (Drs Clark and Saffold), and Kaiser Permanente Health Care Systems, Clackamas, Ore (Dr Israel)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey M.","family":"Israel","sequence":"additional","affiliation":[{"name":"From the Department of Otolaryngology, Head and Neck Surgery, Oregon Health Sciences University, Portland (Drs Clark and Saffold), and Kaiser Permanente Health Care Systems, Clackamas, Ore (Dr Israel)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(88)90044-4"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199106000-00005"},{"key":"e_1_3_1_4_2","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1097\/00006534-199705010-00010","article-title":"Fistula formation and repair after palatal closure: an institutional perspective","volume":"99","author":"Emory Jr RE","year":"1997","unstructured":"Emory Jr RE, , Clay RP, , Bite U, , Jackson IT. Fistula formation and repair after palatal closure: an institutional perspective. Plast Reconstr Surg. 1997; 99:1535-1538.","journal-title":"Plast Reconstr Surg"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(00)90919-4"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198908000-00010"},{"key":"e_1_3_1_7_2","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1097\/00006534-199304001-00008","article-title":"The design of tongue flaps for the closure of palatal fistulas","volume":"91","author":"Assuncao AG","year":"1993","unstructured":"Assuncao AG. The design of tongue flaps for the closure of palatal fistulas. Plast Reconstr Surg. 1993; 91:806-810.","journal-title":"Plast Reconstr Surg"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199507150-00001"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004630-199603000-00006"},{"key":"e_1_3_1_10_2","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/00005373-199709000-00012","article-title":"Analysis of cellular and decellular allogeneic dermal grafts for the treatment of full-thickness wounds in a porcine model","volume":"43","author":"Reagan BJ","year":"1997","unstructured":"Reagan BJ, , Madden MR, , Huo J, , Mathwich M, , Staiano-Coico Not Available. Analysis of cellular and decellular allogeneic dermal grafts for the treatment of full-thickness wounds in a porcine model. J Trauma. 1997; 43:458-466.","journal-title":"J Trauma"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-200001000-00067"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.1.73"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199911000-00020"},{"key":"e_1_3_1_14_2","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1001\/archotol.124.11.1201","article-title":"The use of processed allograft dermal matrix for intraoral resurfacing","volume":"124","author":"Rhee PH","year":"1998","unstructured":"Rhee PH, , Friedman CD, , Ridge JA, , Kusiak J. The use of processed allograft dermal matrix for intraoral resurfacing. Arch Otolaryngol Head Neck Surg. 1998; 124:1201-1204.","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90488-8"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200006000-00020"},{"key":"e_1_3_1_17_2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0022-3468(99)90250-6","article-title":"Evaluation of small intestine submucosa and acellular dermis as diaphragmatic prostheses","volume":"34","author":"Dalla Vecchia L","year":"1999","unstructured":"Dalla Vecchia L, , Engum S, , Kogon B, , Jensen E, , Davis M, , Grosfeld J. Evaluation of small intestine submucosa and acellular dermis as diaphragmatic prostheses. J Pediatr Surg. 1999; 34:167-171.","journal-title":"J Pediatr Surg"}],"container-title":["Archives of Facial Plastic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1001\/archfaci.5.1.40","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1001\/archfaci.5.1.40","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1001\/archfaci.5.1.40","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T17:49:24Z","timestamp":1777571364000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1001\/archfaci.5.1.40"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1,1]]}},"alternative-id":["10.1001\/archfaci.5.1.40"],"URL":"https:\/\/doi.org\/10.1001\/archfaci.5.1.40","relation":{},"ISSN":["1521-2491","1538-3660"],"issn-type":[{"value":"1521-2491","type":"print"},{"value":"1538-3660","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}