{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:38:15Z","timestamp":1785213495255,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Facial Plast Surg"],"published-print":{"date-parts":[[2005,1,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>To systematically record rat facial nerve recovery following crush injury to the main trunk with respect to ocular and vibrissial function and to compare the rates of facial and sciatic nerve recovery from crush injury in the same animals. This serves as a means of validating the functional parameters of facial nerve recovery against the well-known measure of hind limb function, the Sciatic Function Index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The main trunk of the facial nerve and the proximal segment of the sciatic nerve were exposed in all animals. Both nerves were subjected to standardized crush injury and subsequent daily functional testing. After a plateau of functional recovery was achieved, the animals were killed, and the distances between the sites of injury and the end musculature were measured, which allowed determination and comparison of recovery rates in both systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>All crush injuries resulted in loss of electrical conductivity, as proven by intraoperative proximal nerve stimulation. Recovery of ocular and vibrissial motor function occurred starting at postoperative day (POD) 9 and continuing through POD 20. Hind limb function returned later (POD 14-34); however, when corrected for distance, the sciatic recovery rate (2.26 mm\/d) appeared to match that of the facial nerve (1.5-2.4 mm\/d).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Recovery after facial nerve crush injury follows a predictable time course, and the rate of recovery is consistent with that of sciatic nerve injury. Return of the blink reflex, loss of vibrissial fibrillations, and return of vibrissial sweeping function appear to be internally consistent functional measures of facial recovery. These quantitative measures will be useful for future facial nerve manipulation studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/archfaci.7.1.17","type":"journal-article","created":{"date-parts":[[2005,1,17]],"date-time":"2005-01-17T16:17:47Z","timestamp":1105978667000},"page":"17-20","source":"Crossref","is-referenced-by-count":52,"title":["Functional Recovery After Facial and Sciatic Nerve Crush Injury in the Rat"],"prefix":"10.1177","volume":"7","author":[{"given":"Tessa A.","family":"Hadlock","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Heaton","sequence":"additional","affiliation":[{"name":"Department of Surgery, Massachusetts General Hospital, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mack","family":"Cheney","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Mackinnon","sequence":"additional","affiliation":[{"name":"Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, Mo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,1,1]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198901000-00024"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(82)90234-5"},{"key":"e_1_3_1_4_2","first-page":"258","article-title":"A comparison of assessments of functional recovery in the rat","volume":"4","author":"Hadlock T","year":"1999","unstructured":"Hadlock T, , Koka R, , Vacanti J, , Cheney M. A comparison of assessments of functional recovery in the rat. J Peripher Nerv Syst. 1999; 4:258-264. 10642093","journal-title":"J Peripher Nerv Syst"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)90965-0"},{"key":"e_1_3_1_6_2","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1227\/00006123-199509000-00013","article-title":"Quantitative, morphological, and somatotopic nuclear changes after facial nerve regeneration in adult rats: a possible challenge to the \u201cno new neurons\u201d dogma","volume":"37","author":"Fernandez E","year":"1995","unstructured":"Fernandez E, , Pallini R, , Marchese E, , Lauretti L, , LaMarca F. Quantitative, morphological, and somatotopic nuclear changes after facial nerve regeneration in adult rats: a possible challenge to the \u201cno new neurons\u201d dogma. Neurosurgery. 1995; 37:456-463. 7501110","journal-title":"Neurosurgery"},{"key":"e_1_3_1_7_2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3109\/00016488409132939","article-title":"Reorganization of the facial motor nucleus after peripheral nerve regeneration","volume":"97","author":"Thomander L","year":"1984","unstructured":"Thomander L. Reorganization of the facial motor nucleus after peripheral nerve regeneration. Acta Otolaryngol. 1984; 97:619-626. 6464712","journal-title":"Acta Otolaryngol"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200202000-00022"},{"key":"e_1_3_1_9_2","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1006\/exnr.2002.8040","article-title":"An example of neural plasticity evoked by putative behavioral demand and early use of vibrissial hairs after facial nerve transection","volume":"178","author":"Tomov T","year":"2002","unstructured":"Tomov T, , Guntinas-Lichius O, , Grosheva M, et al. An example of neural plasticity evoked by putative behavioral demand and early use of vibrissial hairs after facial nerve transection. Exp Neurol. 2002; 178:207-218. 12504880","journal-title":"Exp Neurol"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.3233\/RNN-2000-00127"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(97)00163-2"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016480310001853"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(199801)34:1<1::AID-NEU1>3.0.CO;2-C"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.6.2.82"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-0102(02)00231-6"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01176997"},{"key":"e_1_3_1_17_2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0006-8993(80)90252-8","article-title":"Cytophotometric quantification of retrograde axonal transport of a fluorescent tracer (primuline) in mouse facial neurons","volume":"186","author":"Enerback L","year":"1980","unstructured":"Enerback L, , Kristensson K, , Olsson T. Cytophotometric quantification of retrograde axonal transport of a fluorescent tracer (primuline) in mouse facial neurons. 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