{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T14:52:05Z","timestamp":1791039125216,"version":"4.1.0"},"reference-count":0,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Neurol"],"published-print":{"date-parts":[[2008,8,1]]},"DOI":"10.1001\/archneur.65.8.1102","type":"journal-article","created":{"date-parts":[[2008,8,11]],"date-time":"2008-08-11T16:14:31Z","timestamp":1218471271000},"source":"Crossref","is-referenced-by-count":183,"title":["Elevated Cerebrospinal Fluid BACE1 Activity in Incipient Alzheimer Disease"],"prefix":"10.1001","volume":"65","author":[{"given":"Henrik","family":"Zetterberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Andreasson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oskar","family":"Hansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoxin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sethu","family":"Sankaranarayanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malin E.","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peder","family":"Buchhave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabet","family":"Londos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Umek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart","family":"Minthon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam J.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaj","family":"Blennow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","container-title":["Archives of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/jamanetwork.com\/journals\/jamaneurology\/fullarticle\/796042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,12,16]],"date-time":"2016-12-16T23:09:47Z","timestamp":1481929787000},"score":1,"resource":{"primary":{"URL":"http:\/\/archneur.jamanetwork.com\/article.aspx?doi=10.1001\/archneur.65.8.1102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8,1]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,8,11]]}},"URL":"https:\/\/doi.org\/10.1001\/archneur.65.8.1102","relation":{},"ISSN":["0003-9942"],"issn-type":[{"value":"0003-9942","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8,1]]}}}