{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T07:21:19Z","timestamp":1781421679218,"version":"3.54.1"},"reference-count":18,"publisher":"American Medical Association (AMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arch Gen Psychiatry"],"published-print":{"date-parts":[[2002,6,1]]},"DOI":"10.1001\/archpsyc.59.6.567","type":"journal-article","created":{"date-parts":[[2003,3,18]],"date-time":"2003-03-18T11:45:16Z","timestamp":1047987916000},"page":"567","source":"Crossref","is-referenced-by-count":15,"title":["Response Differences of Spontaneous Panic and Fear"],"prefix":"10.1001","volume":"59","author":[{"given":"Donald F.","family":"Klein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"key":"REF-YLT0602-7-1-1","unstructured":"JMGormanJKentJMartinezSBrowneJCoplanLAPappPhysiological changes during carbon dioxide inhalation in patients\nwith panic disorder, major depression, and premenstrual dysphoric disorder:\nevidence for a central fear mechanism.Arch Gen Psychiatry.200158125131."},{"key":"REF-YLT0602-7-1-2","unstructured":"DFKleinFalse suffocation alarms, spontaneous panics, and related conditions:\nan integrative hypothesis.Arch Gen Psychiatry.199350306317."},{"key":"REF-YLT0602-7-1-3","unstructured":"DFKleinTesting the suffocation false alarm theory of panic disorder.Anxiety.1994117"},{"key":"REF-YLT0602-7-1-4","unstructured":"JMGormanLAPappJDCoplanJMMartinezSLennonRRGoetzDRossDFKleinAnxiogenic effects of CO2 and hyperventilation in patients\nwith panic disorder.Am J Psychiatry.1994151547553."},{"key":"REF-YLT0602-7-1-5","unstructured":"LAPappJMMartinezDFKleinJDCoplanRGNormanRColeMJde JesusDRossRGoetzJMGormanRespiratory psychophysiology of panic disorder.Am J Psychiatry.199715415571565."},{"key":"REF-YLT0602-7-1-6","unstructured":"LAPappJMMartinezDFKleinJCoplanJMGormanRebreathing tests in panic disorder.Biol Psychiatry.199538240245."},{"key":"REF-YLT0602-7-1-7","unstructured":"MCFPaynePanic disorder: the ventilatory response to carbon dioxide, respiratory\nvariables.Psychosom Med.198850541548."},{"key":"REF-YLT0602-7-1-8","unstructured":"JMGormanMRFyerRGoetzJAskanaziMRLiebowitzAJFyerJKinneyDFKleinRespiratory physiology of patients with panic disorder.Arch Gen Psychiatry.1988453139."},{"key":"REF-YLT0602-7-1-9","unstructured":"RRGoetzDFKleinDJGullyJKahnMRLiebowitzAJFyerJMGormanPanic attacks during placebo procedures in the laboratory: physiology\nand symptomatology.Arch Gen Psychiatry.199350280285"},{"key":"REF-YLT0602-7-1-10","unstructured":"PRoy-ByrneMBSteinInspiring panic.Arch Gen Psychiatry.200158123124."},{"key":"REF-YLT0602-7-1-11","unstructured":"DFKleinAnxiety reconceptualized: gleaning from pharmacological dissection\u2014early\nexperience with imipramine and anxiety.KleinDFRabkinJGedsAnxiety: New Research\nand Changing Concepts.New York, NYRaven Press1981235262"},{"key":"REF-YLT0602-7-1-12","unstructured":"BHFriedmanJFThayerAutonomic balance revisited: panic anxiety and heart rate variability.J Psychosom Res.199844133151"},{"key":"REF-YLT0602-7-1-13","unstructured":"DGozalGMHathoutKAKirlewHTangMSWooJZhangRBLufkinRMHarperLocalization of putative neural respiratory regions in the human by\nfunctional magnetic resonance imaging.J Appl Physiol.19947620762083."},{"key":"REF-YLT0602-7-1-14","unstructured":"DRCorfieldGRFinkSCRamsayKMurphyHRHartyJDWatsonLAdamsRSFrackowiakAGuzEvidence for limbic system activation during CO2-stimulated\nbreathing in man.J Physiol.199548817784"},{"key":"REF-YLT0602-7-1-15","unstructured":"LMParsonsGEganMLiottiSBrannanDDentonRShadeRRobillardLMaddenBAbplanalpPTFoxNeuroimaging evidence implicating cerebellum in the experience of hypercapnia\nand hunger for air.Proc Natl Acad Sci U S A.20019820412046."},{"key":"REF-YLT0602-7-1-16","unstructured":"SBrannanMLiottiGEganRShadeLMaddenRRobillardBAbplanalpKStoferDDentonPTFoxNeuroimaging of cerebral activations and deactivations associated with\nhypercapnia and hunger for air.Proc Natl Acad Sci U S A.20019820292034."},{"key":"REF-YLT0602-7-1-17","unstructured":"MLiottiSBrannanGEganRShadeLMaddenBAbplanalpRRobillardJLancasterFEZamarripaPTFoxDDentonBrain responses associated with consciousness of breathlessness (air\nhunger).Proc Natl Acad Sci U S A.20019820352040."},{"key":"REF-YLT0602-7-1-18","unstructured":"DFKleinHarmful dysfunction, disorder, disease, illness, and evolution.J Abnorm Psychol.1999108421429."}],"container-title":["Archives of General Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/articlepdf\/206405\/ylt0602.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T22:30:33Z","timestamp":1764973833000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/206405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6,1]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2002,6,1]]}},"URL":"https:\/\/doi.org\/10.1001\/archpsyc.59.6.567","relation":{},"ISSN":["0003-990X"],"issn-type":[{"value":"0003-990X","type":"print"}],"subject":[],"published":{"date-parts":[[2002,6,1]]}}}