{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T14:08:13Z","timestamp":1790431693678,"version":"4.1.0"},"reference-count":25,"publisher":"American Medical Association (AMA)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2020,11,10]]},"DOI":"10.1001\/jama.2020.18889","type":"journal-article","created":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T20:41:49Z","timestamp":1605040909000},"page":"1844","source":"Crossref","is-referenced-by-count":94,"title":["Effect of e-Cigarettes Plus Counseling vs Counseling Alone on Smoking Cessation"],"prefix":"10.1001","volume":"324","author":[{"given":"Mark J.","family":"Eisenberg","sequence":"first","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Departments of Medicine and Epidemiology, Biostatistics, and Occupational Health, McGill University, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Division of Cardiology, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9a","family":"H\u00e9bert-Losier","sequence":"additional","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah B.","family":"Windle","sequence":"additional","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Greenspoon","sequence":"additional","affiliation":[{"name":"Hamilton Community Health Centre, Family Health Organization, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Brandys","sequence":"additional","affiliation":[{"name":"Ottawa Hospital, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e0s","family":"F\u00fcl\u00f6p","sequence":"additional","affiliation":[{"name":"Centre de recherche sur le vieillissement, Sherbrooke, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thang","family":"Nguyen","sequence":"additional","affiliation":[{"name":"St Boniface Hospital, Winnipeg, Manitoba, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Elkouri","sequence":"additional","affiliation":[{"name":"Division of Vascular Surgery, Centre hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Montigny","sequence":"additional","affiliation":[{"name":"Centre int\u00e9gr\u00e9 de sant\u00e9 et de services sociaux de Laval, H\u00f4pital Cit\u00e9-de-la-Sant\u00e9, Laval, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Wilderman","sequence":"additional","affiliation":[{"name":"Wilderman Medical Clinic\/Canadian Centre for Clinical Trials, Thornhill, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier F.","family":"Bertrand","sequence":"additional","affiliation":[{"name":"Institut de Cardiologie et de Pneumologie de Qu\u00e9bec (IUCPQ), Qu\u00e9bec City, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna Alexis","family":"Bostwick","sequence":"additional","affiliation":[{"name":"H\u00f4pital Montfort, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Abrahamson","sequence":"additional","affiliation":[{"name":"Michael Garron Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Lacasse","sequence":"additional","affiliation":[{"name":"Institut de Cardiologie et de Pneumologie de Qu\u00e9bec (IUCPQ), Qu\u00e9bec City, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smita","family":"Pakhale","sequence":"additional","affiliation":[{"name":"The Ottawa Hospital Research Institute\/The Bridge Engagement Centre, Ottawa, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josselin","family":"Cabaussel","sequence":"additional","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian B.","family":"Filion","sequence":"additional","affiliation":[{"name":"Lady Davis Institute, Jewish General Hospital, Montr\u00e9al, Qu\u00e9bec, Canada"},{"name":"Departments of Medicine and Epidemiology, Biostatistics, and Occupational Health, McGill University, Montr\u00e9al, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"E3 Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"1","key":"joi200107r2","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-006229","article-title":"Association between duration of use of pharmacotherapy and smoking cessation: findings from a national survey.","volume":"5","author":"Siahpush","year":"2015","journal-title":"BMJ Open"},{"issue":"7","key":"joi200107r3","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1056\/NEJMoa1808779","article-title":"A randomized trial of e-cigarettes versus nicotine-replacement therapy.","volume":"380","author":"Hajek","year":"2019","journal-title":"N Engl J Med"},{"issue":"9905","key":"joi200107r4","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1016\/S0140-6736(13)61842-5","article-title":"Electronic cigarettes for smoking cessation: a randomised controlled trial.","volume":"382","author":"Bullen","year":"2013","journal-title":"Lancet"},{"issue":"6","key":"joi200107r5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0066317","article-title":"EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as tobacco cigarettes substitute: a prospective 12-month randomized control design study.","volume":"8","author":"Caponnetto","year":"2013","journal-title":"PLoS One"},{"issue":"4","key":"joi200107r6","doi-asserted-by":"publisher","first-page":"567","DOI":"10.3122\/jabfm.2019.04.180384","article-title":"Effect of electronic cigarettes on smoking reduction and cessation in Korean male smokers: a randomized controlled study.","volume":"32","author":"Lee","year":"2019","journal-title":"J Am Board Fam Med"},{"issue":"1","key":"joi200107r7","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1093\/ntr\/nty047","article-title":"E-cigarettes may support smokers with high smoking-related risk awareness to stop smoking in the short run: preliminary results by randomized controlled trial.","volume":"21","author":"Masiero","year":"2019","journal-title":"Nicotine Tob Res"},{"issue":"1","key":"joi200107r8","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/S2213-2600(19)30269-3","article-title":"Nicotine patches used in combination with e-cigarettes (with and without nicotine) for smoking cessation: a pragmatic, randomised trial.","volume":"8","author":"Walker","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"12","key":"joi200107r9","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1158\/1055-9965.EPI-17-0460","article-title":"A naturalistic, randomized pilot trial of e-cigarettes: uptake, exposure, and behavioral effects.","volume":"26","author":"Carpenter","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"24","key":"joi200107r10","doi-asserted-by":"publisher","first-page":"2302","DOI":"10.1056\/NEJMsa1715757","article-title":"A pragmatic trial of e-cigarettes, incentives, and drugs for smoking cessation.","volume":"378","author":"Halpern","year":"2018","journal-title":"N Engl J Med"},{"issue":"10","key":"joi200107r11","doi-asserted-by":"publisher","first-page":"1937","DOI":"10.1093\/ntr\/ntw017","article-title":"A randomized trial comparing the effect of nicotine versus placebo electronic cigarettes on smoking reduction among young adult smokers.","volume":"18","author":"Tseng","year":"2016","journal-title":"Nicotine Tob Res"},{"issue":"3","key":"joi200107r12","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.cjco.2020.03.006","article-title":"A randomized controlled trial evaluating the efficacy of e-Cigarette use for smoking cessation in the general population: E3 trial design.","volume":"2","author":"H\u00e9bert-Losier","year":"2020","journal-title":"CJC Open"},{"issue":"1","key":"joi200107r13","first-page":"129","article-title":"External validation of the Motivation To Stop Scale (MTSS): findings from the International Tobacco Control (ITC) Netherlands Survey.","volume":"27","author":"Hummel","year":"2017","journal-title":"Eur J Public Health"},{"issue":"9","key":"joi200107r14","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1111\/add.1991.86.issue-9","article-title":"The Fagerstr\u00f6m Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire.","volume":"86","author":"Heatherton","year":"1991","journal-title":"Br J Addict"},{"issue":"5","key":"joi200107r15","doi-asserted-by":"publisher","first-page":"443","DOI":"10.5993\/AJHB.29.5.7","article-title":"Developmental history of the Glover-Nilsson Smoking Behavioral Questionnaire.","volume":"29","author":"Glover","year":"2005","journal-title":"Am J Health Behav"},{"issue":"2","key":"joi200107r17","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1080\/14622200210123581","article-title":"Biochemical verification of tobacco use and cessation.","volume":"4","author":"SRNT Subcommittee on Biochemical Verification","year":"2002","journal-title":"Nicotine Tob Res"},{"issue":"2","key":"joi200107r18","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1503\/cmaj.070256","article-title":"Pharmacotherapies for smoking cessation: a meta-analysis of randomized controlled trials.","volume":"179","author":"Eisenberg","year":"2008","journal-title":"CMAJ"},{"key":"joi200107r19","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1186\/s12916-015-0505-2","article-title":"Does reduced smoking if you can\u2019t stop make any difference?","volume":"13","author":"Begh","year":"2015","journal-title":"BMC Med"},{"issue":"3","key":"joi200107r20","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1037\/0022-006X.72.3.371","article-title":"Both smoking reduction with nicotine replacement therapy and motivational advice increase future cessation among smokers unmotivated to quit.","volume":"72","author":"Carpenter","year":"2004","journal-title":"J Consult Clin Psychol"},{"issue":"2","key":"joi200107r21","doi-asserted-by":"publisher","first-page":"44","DOI":"10.15585\/mmwr.mm6902e2","article-title":"Update: product, substance-use, and demographic characteristics of hospitalized patients in a nationwide outbreak of e-cigarette, or vaping, product use-associated lung injury: United States, August 2019\u2013January 2020.","volume":"69","author":"Ellington","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"8","key":"joi200107r22","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1056\/NEJMoa1916433","article-title":"Vitamin E acetate in bronchoalveolar-lavage fluid associated with EVALI.","volume":"382","author":"Blount","year":"2020","journal-title":"N Engl J Med"},{"issue":"1","key":"joi200107r23","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1164\/rccm.201710-2033OC","article-title":"Chronic e-cigarette exposure alters the human bronchial epithelial proteome.","volume":"198","author":"Ghosh","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"joi200107r24","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1164\/rccm.201903-0615OC","article-title":"Chronic e-cigarette use increases neutrophil elastase and matrix metalloprotease levels in the lung.","volume":"200","author":"Ghosh","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"joi200107r25","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1164\/rccm.201708-1590OC","article-title":"e-Cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion.","volume":"197","author":"Reidel","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"key":"joi200107r1","volume-title":"The Health Consequences of Smoking: 50 Years of Progress: A Report of the Surgeon General","author":"National Center for Chronic Disease Prevention","year":"2014"},{"key":"joi200107r16","first-page":"490","volume-title":"Beck Depression Inventory-II","author":"Beck","year":"1996"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2772759\/jama_eisenberg_2020_oi_200107_1604686237.83798.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T20:41:59Z","timestamp":1605040919000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2772759"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2020,11,10]]},"references-count":25,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2020,11,10]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2020.18889","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,10]]}}}