{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T11:13:21Z","timestamp":1781608401819,"version":"3.54.5"},"reference-count":17,"publisher":"American Medical Association (AMA)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2020,4,14]]},"DOI":"10.1001\/jama.2020.2070","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T15:32:49Z","timestamp":1586878369000},"page":"1351","source":"Crossref","is-referenced-by-count":8,"title":["A New Vaccine for Chikungunya Virus"],"prefix":"10.1001","volume":"323","author":[{"given":"Kenneth A.","family":"Stapleford","sequence":"first","affiliation":[{"name":"NYU Grossman School of Medicine, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Mulligan","sequence":"additional","affiliation":[{"name":"NYU Grossman School of Medicine, NYU Langone Vaccine Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"9916","key":"jed200012r1","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/S0140-6736(14)60185-9","article-title":"Chikungunya in the Americas.","volume":"383","author":"Leparc-Goffart","year":"2014","journal-title":"Lancet"},{"issue":"13","key":"jed200012r2","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1056\/NEJMra1406035","article-title":"Chikungunya virus and the global spread of a mosquito-borne disease.","volume":"372","author":"Weaver","year":"2015","journal-title":"N Engl J Med"},{"issue":"2","key":"jed200012r3","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1097\/RHU.0000000000000868","article-title":"Pan-American League of Associations for Rheumatology-Central American, Caribbean and Andean Rheumatology Association consensus-conference endorsements and recommendations on the diagnosis and treatment of chikungunya-related inflammatory arthropathies in Latin America.","volume":"25","author":"Monge","year":"2019","journal-title":"J Clin Rheumatol"},{"key":"jed200012r4","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.coviro.2017.01.003","article-title":"Persistent RNA virus infections: do PAMPS drive chronic disease?","volume":"23","author":"McCarthy","year":"2017","journal-title":"Curr Opin Virol"},{"issue":"5","key":"jed200012r5","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1002\/art.39027","article-title":"Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis.","volume":"67","author":"Miner","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"jed200012r6","doi-asserted-by":"publisher","first-page":"390","DOI":"10.12688\/f1000research","article-title":"Cardiovascular involvement and manifestations of systemic Chikungunya virus infection: a systematic review.","volume":"6","author":"Alvarez","year":"2017","journal-title":"F1000Res"},{"issue":"12","key":"jed200012r7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207406","article-title":"Atypical and severe manifestations of chikungunya virus infection in French Guiana: a hospital-based study.","volume":"13","author":"Bonifay","year":"2018","journal-title":"PLoS One"},{"issue":"4","key":"jed200012r8","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1097\/BOR.0000000000000396","article-title":"Chikungunya virus and autoimmunity.","volume":"29","author":"Tanay","year":"2017","journal-title":"Curr Opin Rheumatol"},{"issue":"11","key":"jed200012r9","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1590\/0004-282x20160138","article-title":"Neurological manifestations of chikungunya and zika infections.","volume":"74","author":"Pinheiro","year":"2016","journal-title":"Arq Neuropsiquiatr"},{"issue":"3","key":"jed200012r10","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1038\/nm.2105","article-title":"A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection.","volume":"16","author":"Akahata","year":"2010","journal-title":"Nat Med"},{"issue":"9959","key":"jed200012r11","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1016\/S0140-6736(14)61185-5","article-title":"Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial.","volume":"384","author":"Chang","year":"2014","journal-title":"Lancet"},{"issue":"10","key":"jed200012r12","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1093\/infdis\/jiw431","article-title":"A virus-like particle vaccine elicits broad neutralizing antibody responses in humans to all chikungunya virus genotypes.","volume":"214","author":"Goo","year":"2016","journal-title":"J Infect Dis"},{"key":"jed200012r13","article-title":"Effect of a chikungunya virus-like particle vaccine on safety and tolerability: a randomized clinical trial.","author":"Chen","journal-title":"JAMA"},{"issue":"8","key":"jed200012r14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004960","article-title":"Antigenic variation of East\/Central\/South African and Asian chikungunya virus genotypes in neutralization by immune sera.","volume":"10","author":"Chua","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"jed200012r15","doi-asserted-by":"crossref","DOI":"10.3390\/v11020175","article-title":"Tropism of the chikungunya virus.","volume":"11","author":"Matusali","year":"2019","journal-title":"Viruses"},{"key":"jed200012r16","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72?314 cases from the Chinese Center for Disease Control and Prevention.","author":"Zuynyou","journal-title":"JAMA"},{"issue":"9916","key":"jed200012r17","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S0140-6736(14)60167-7","article-title":"Chikungunya\u2014coming to America.","volume":"383","year":"2014","journal-title":"Lancet"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2764440\/jama_stapleford_2020_ed_200012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T15:32:51Z","timestamp":1586878371000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2764440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,14]]},"references-count":17,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2020,4,14]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2020.2070","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4,14]]}}}