{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:18:30Z","timestamp":1791901110235,"version":"4.3.4"},"reference-count":37,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2021,2,16]]},"DOI":"10.1001\/jama.2021.0247","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:37:46Z","timestamp":1613695066000},"page":"658","source":"Crossref","is-referenced-by-count":128,"title":["Associations of Maternal Cardiovascular Health in Pregnancy With Offspring Cardiovascular Health in Early Adolescence"],"prefix":"10.1001","volume":"325","author":[{"given":"Amanda M.","family":"Perak","sequence":"first","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"},{"name":"Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Lancki","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Kuang","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darwin R.","family":"Labarthe","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norrina B.","family":"Allen","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svati H.","family":"Shah","sequence":"additional","affiliation":[{"name":"Duke University Medical Center, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn P.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Grobman","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean M.","family":"Lawrence","sequence":"additional","affiliation":[{"name":"Kaiser Permanente of Southern California, Pasadena"},{"name":"currently with Division of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald M.","family":"Lloyd-Jones","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"William L.","family":"Lowe","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise M.","family":"Scholtens","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"HAPO Follow-Up Study Cooperative Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"20","key":"joi210003r1","doi-asserted-by":"publisher","first-page":"2066","DOI":"10.1161\/CIRCULATIONAHA.113.001805","article-title":"Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular disease.","volume":"129","author":"Palinski","year":"2014","journal-title":"Circulation"},{"key":"joi210003r2","doi-asserted-by":"publisher","first-page":"f4539","DOI":"10.1136\/bmj.f4539","article-title":"Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years.","volume":"347","author":"Reynolds","year":"2013","journal-title":"BMJ"},{"key":"joi210003r3","doi-asserted-by":"publisher","first-page":"l6398","DOI":"10.1136\/bmj.l6398","article-title":"Maternal diabetes during pregnancy and early onset of cardiovascular disease in offspring: population based cohort study with 40 years of follow-up.","volume":"367","author":"Yu","year":"2019","journal-title":"BMJ"},{"issue":"1","key":"joi210003r4","doi-asserted-by":"publisher","first-page":"75.e1","DOI":"10.1016\/j.ajog.2019.07.024","article-title":"Risks of cause-specific mortality in offspring of pregnancies complicated by hypertensive disease of pregnancy.","volume":"222","author":"Hammad","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"6279","key":"joi210003r5","doi-asserted-by":"publisher","first-page":"1847","DOI":"10.1136\/bmj.282.6279.1847","article-title":"Strategy of prevention: lessons from cardiovascular disease.","volume":"282","author":"Rose","year":"1981","journal-title":"Br Med J (Clin Res Ed)"},{"issue":"4","key":"joi210003r6","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1161\/CIRCULATIONAHA.109.192703","article-title":"Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association\u2019s strategic Impact Goal through 2020 and beyond.","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"issue":"9","key":"joi210003r7","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics-2020 update: a report from the American Heart Association.","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"24","key":"joi210003r8","doi-asserted-by":"publisher","first-page":"e843","DOI":"10.1161\/CIR.0000000000000582","article-title":"Promoting risk identification and reduction of cardiovascular disease in women through collaboration with obstetricians and gynecologists: a presidential advisory from the American Heart Association and the American College of Obstetricians and Gynecologists.","volume":"137","author":"Brown","year":"2018","journal-title":"Circulation"},{"key":"joi210003r9","article-title":"Associations of gestational cardiovascular health with pregnancy outcomes: the Hyperglycemia and Adverse Pregnancy Outcome study.","author":"Perak","year":"2020","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"joi210003r10","doi-asserted-by":"publisher","first-page":"676","DOI":"10.2337\/dc09-1848","article-title":"International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy.","volume":"33","author":"Metzger","year":"2010","journal-title":"Diabetes Care"},{"issue":"1","key":"joi210003r11","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0020-7292(02)00092-9","article-title":"The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.","volume":"78","author":"HAPO Study Cooperative Research Group","year":"2002","journal-title":"Int J Gynaecol Obstet"},{"issue":"4","key":"joi210003r12","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1177\/1740774506070695","article-title":"Integration of local and central laboratory functions in a worldwide multicentre study: experience from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.","volume":"3","author":"Nesbitt","year":"2006","journal-title":"Clin Trials"},{"issue":"19","key":"joi210003r13","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1056\/NEJMoa0707943","article-title":"Hyperglycemia and adverse pregnancy outcomes.","volume":"358","author":"Metzger","year":"2008","journal-title":"N Engl J Med"},{"issue":"10","key":"joi210003r14","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1001\/jama.2018.11628","article-title":"Association of gestational diabetes with maternal disorders of glucose metabolism and childhood adiposity.","volume":"320","author":"Lowe","year":"2018","journal-title":"JAMA"},{"issue":"18","key":"joi210003r15","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1161\/CIRCULATIONAHA.116.026252","article-title":"Favorable cardiovascular health, compression of morbidity, and healthcare costs: forty-year follow-up of the CHA Study (Chicago Heart Association Detection Project in Industry).","volume":"135","author":"Allen","year":"2017","journal-title":"Circulation"},{"issue":"1","key":"joi210003r16","first-page":"1","article-title":"ACOG Practice Bulletin No. 202: gestational hypertension and preeclampsia.","volume":"133","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"4","key":"joi210003r17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/AOG.0000000000002353","article-title":"Committee Opinion No. 721 summary: smoking cessation during pregnancy.","volume":"130","year":"2017","journal-title":"Obstet Gynecol"},{"issue":"5","key":"joi210003r18","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1111\/j.1471-0528.2009.02486.x","article-title":"Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) Study: associations with maternal body mass index.","volume":"117","author":"HAPO Study Cooperative Research Group","year":"2010","journal-title":"BJOG"},{"issue":"6","key":"joi210003r19","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1097\/AOG.0b013e3181c2bde8","article-title":"Pregnancy and laboratory studies: a reference table for clinicians.","volume":"114","author":"Abbassi-Ghanavati","year":"2009","journal-title":"Obstet Gynecol"},{"issue":"4","key":"joi210003r20","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.015123","article-title":"Cardiovascular health among pregnant women, aged 20 to 44 years, in the United States.","volume":"9","author":"Perak","year":"2020","journal-title":"J Am Heart Assoc"},{"issue":"17","key":"joi210003r21","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1001\/jama.2018.16975","article-title":"Association of change in cardiovascular risk factors with incident cardiovascular events.","volume":"320","author":"van Sloten","year":"2018","journal-title":"JAMA"},{"issue":"4","key":"joi210003r22","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1111\/ijpo.2012.7.issue-4","article-title":"Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity.","volume":"7","author":"Cole","year":"2012","journal-title":"Pediatr Obes"},{"issue":"3","key":"joi210003r23","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-1904","article-title":"Clinical practice guideline for screening and management of high blood pressure in children and adolescents.","volume":"140","author":"Flynn","year":"2017","journal-title":"Pediatrics"},{"key":"joi210003r25","doi-asserted-by":"publisher","first-page":"S14","DOI":"10.2337\/dc20-S002","article-title":"2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2020.","volume":"43","author":"American Diabetes Association","year":"2020","journal-title":"Diabetes Care"},{"issue":"1","key":"joi210003r27","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S2213-8587(16)30107-3","article-title":"Influence of maternal obesity on the long-term health of offspring.","volume":"5","author":"Godfrey","year":"2017","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"1","key":"joi210003r28","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1111\/apha.2017.219.issue-1","article-title":"Pregnancy as a critical window for blood pressure regulation in mother and child: programming and reprogramming.","volume":"219","author":"Paauw","year":"2017","journal-title":"Acta Physiol (Oxf)"},{"issue":"5","key":"joi210003r29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0126327","article-title":"Metabolic profile in early pregnancy is associated with offspring adiposity at 4 years of age: the Rhea pregnancy cohort Crete, Greece.","volume":"10","author":"Daraki","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"joi210003r30","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/sj.ijo.0803760","article-title":"Maternal smoking during pregnancy and child overweight: systematic review and meta-analysis.","volume":"32","author":"Oken","year":"2008","journal-title":"Int J Obes (Lond)"},{"key":"joi210003r31","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/2419263","article-title":"Marked disparities in pre-pregnancy obesity and overweight prevalence among us women by race\/ethnicity, nativity\/immigrant status, and sociodemographic characteristics, 2012-2014.","volume":"2019","author":"Singh","year":"2019","journal-title":"J Obes"},{"issue":"16","key":"joi210003r32","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1161\/CIRCULATIONAHA.111.073585","article-title":"Ideal cardiovascular health in childhood and cardiometabolic outcomes in adulthood: the Cardiovascular Risk in Young Finns Study.","volume":"125","author":"Laitinen","year":"2012","journal-title":"Circulation"},{"issue":"12","key":"joi210003r33","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1001\/jamacardio.2018.3546","article-title":"Epigenetic hallmarks of fetal early atherosclerotic lesions in humans.","volume":"3","author":"de Nigris","year":"2018","journal-title":"JAMA Cardiol"},{"key":"joi210003r34","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.jpeds.2018.12.008","article-title":"Cardiovascular risk factors in offspring of preeclamptic pregnancies: systematic review and meta-analysis.","volume":"208","author":"Andraweera","year":"2019","journal-title":"J Pediatr"},{"issue":"23","key":"joi210003r35","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.008870","article-title":"Birth weight and risk of type 2 diabetes mellitus, cardiovascular disease, and hypertension in adults: a meta-analysis of 7 646 267 participants from 135 studies.","volume":"7","author":"Knop","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"joi210003r36","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.jpeds.2019.01.042","article-title":"Promoting cardiovascular health in early childhood and transitions in childhood through adolescence: a workshop report.","volume":"209","author":"Daniels","year":"2019","journal-title":"J Pediatr"},{"issue":"3","key":"joi210003r37","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1017\/S204017441800082X","article-title":"Diet and physical activity in pregnancy and offspring\u2019s cardiovascular health: a systematic review.","volume":"10","author":"van Elten","year":"2019","journal-title":"J Dev Orig Health Dis"},{"key":"joi210003r24","unstructured":"National Heart, Lung, and Blood Institute. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: full report. Published October 2012. Accessed August 21, 2020. https:\/\/www.nhlbi.nih.gov\/health-pro\/guidelines\/current\/cardiovascular-health-pediatric-guidelines"},{"key":"joi210003r26","unstructured":"R Core Team. R: A language and environment for statistical computing. R Project for Statistical Computing. Accessed April 8, 2020. https:\/\/www.R-project.org\/"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2776329\/jama_perak_2021_oi_210003_1613412638.41998.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:38:01Z","timestamp":1613695081000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2776329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,16]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,2,16]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2021.0247","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2,16]]}}}