{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:59:22Z","timestamp":1793411962310,"version":"4.5.0"},"reference-count":40,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2022,1,4]]},"DOI":"10.1001\/jama.2021.22647","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T11:37:18Z","timestamp":1640000238000},"page":"50","source":"Crossref","is-referenced-by-count":389,"title":["Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery"],"prefix":"10.1001","volume":"327","author":[{"given":"Ting","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"Clinical Research Unit, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyong","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Ningbo No. 6 Hospital, Ningbo, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinze","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The First Affiliated Hospital of Wenzhou Medical University, The First Provincial Wenzhou Hospital of Zhejiang, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenchen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Clinical Research Unit, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Daniels","sequence":"additional","affiliation":[{"name":"Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajnikant Laxmishanker","family":"Mehta","sequence":"additional","affiliation":[{"name":"Birmingham Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingcang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce","family":"Yeung","sequence":"additional","affiliation":[{"name":"Warwick Clinical Trials Unit, University of Warwick, Warwick, United Kingdom"},{"name":"University Hospitals of Birmingham NHS Foundation Trust, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jackson","sequence":"additional","affiliation":[{"name":"Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Melody","sequence":"additional","affiliation":[{"name":"University Hospitals of Birmingham NHS Foundation Trust, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengwei","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinguang","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care, Lishui Municipal People\u2019s Hospital, Lishui Central Hospital, and Fifth Affiliated Hospital of Wenzhou Medical College, Lishui, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care, Lishui City People's Hospital, Lishui, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo No. 2 Hospital, Ningbo, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang Gao","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"},{"name":"University Hospitals of Birmingham NHS Foundation Trust, Birmingham, United Kingdom"},{"name":"Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingquan","family":"Lian","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"RAGA Study Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Lin","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfeng","family":"Ma","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wangning","family":"Shangguan","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuntong","family":"Zhang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Wang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuokai","family":"Xie","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"He","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenwen","family":"Lin","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyu","family":"Xiang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianlin","family":"Wang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingsi","family":"Kong","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibing","family":"Wang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nana","family":"Bao","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuzhong","family":"Xu","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Cheng","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lipei","family":"Lei","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengqiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Fan","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yini","family":"Wu","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Wei","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhonghua","family":"Shi","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Mei","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foquan","family":"Luo","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Zhao","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Zhang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shibiao","family":"Chen","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Shi","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanbo","family":"Liang","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Xu","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weihe","family":"Zhou","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwei","family":"Zheng","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Yuan","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Lin","sequence":"additional","affiliation":[{"name":"for the RAGA Study Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"8","key":"joi210137r1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003180","article-title":"Incidence of and trends in hip fracture among adults in urban China: a nationwide retrospective cohort study.","volume":"17","author":"Zhang","year":"2020","journal-title":"PLoS Med"},{"issue":"2","key":"joi210137r2","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1007\/s40520-016-0541-6","article-title":"Risk factors for postoperative delirium following hip fracture repair in elderly patients: a systematic review and meta-analysis.","volume":"29","author":"Yang","year":"2017","journal-title":"Aging Clin Exp Res"},{"issue":"9","key":"joi210137r3","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1056\/NEJM199903043400901","article-title":"A multicomponent intervention to prevent delirium in hospitalized older patients.","volume":"340","author":"Inouye","year":"1999","journal-title":"N Engl J Med"},{"issue":"9","key":"joi210137r4","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1097\/EJA.0b013e328349b7f5","article-title":"Postoperative delirium, part 1: pathophysiology and risk factors.","volume":"28","author":"Steiner","year":"2011","journal-title":"Eur J Anaesthesiol"},{"issue":"9106","key":"joi210137r5","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1016\/S0140-6736(97)07382-0","article-title":"Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study.","volume":"351","author":"Moller","year":"1998","journal-title":"Lancet."},{"issue":"2","key":"joi210137r6","doi-asserted-by":"publisher","first-page":"e190111","DOI":"10.1001\/jamanetworkopen.2019.0111","article-title":"Association of duration of surgery with postoperative delirium among patients receiving hip fracture repair.","volume":"2","author":"Ravi","year":"2019","journal-title":"JAMA Netw Open"},{"issue":"12","key":"joi210137r7","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-020757","article-title":"Effect of regional versus general anaesthesia on postoperative delirium in elderly patients undergoing surgery for hip fracture: a systematic review.","volume":"8","author":"Patel","year":"2018","journal-title":"BMJ Open"},{"issue":"2","key":"joi210137r8","article-title":"Anaesthesia for hip fracture surgery in adults.","volume":"2","author":"Guay","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"7650","key":"joi210137r9","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1136\/bmj.39489.470347.AD","article-title":"GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.","volume":"336","author":"Guyatt","year":"2008","journal-title":"BMJ"},{"issue":"1","key":"joi210137r10","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.bja.2017.09.002","article-title":"Perioperative outcomes in the context of mode of anaesthesia for patients undergoing hip fracture surgery: systematic review and meta-analysis.","volume":"120","author":"O\u2019Donnell","year":"2018","journal-title":"Br J Anaesth"},{"issue":"4","key":"joi210137r11","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1097\/EJA.0000000000000594","article-title":"European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium.","volume":"34","author":"Aldecoa","year":"2017","journal-title":"Eur J Anaesthesiol"},{"issue":"3","key":"joi210137r12","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1017\/S1041610298005390","article-title":"Detection and diagnosis of delirium in the elderly: psychiatrist diagnosis, confusion assessment method, or consensus diagnosis?","volume":"10","author":"Zou","year":"1998","journal-title":"Int Psychogeriatr"},{"issue":"3","key":"joi210137r13","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d a practical method for grading the cognitive state of patients for the clinician.","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"issue":"3","key":"joi210137r14","first-page":"108","article-title":"The application of the Chinese version of Mini Mental State Examination.","volume":"7","author":"Wang","year":"1989","journal-title":"Shanghai Psychiatry Medicine."},{"issue":"6","key":"joi210137r16","doi-asserted-by":"publisher","first-page":"R764","DOI":"10.1186\/cc3909","article-title":"The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study.","volume":"9","author":"Gao","year":"2005","journal-title":"Crit Care"},{"issue":"1","key":"joi210137r17","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.comppsych.2008.05.011","article-title":"Chinese version of the Delirium Rating Scale-Revised-98: reliability and validity.","volume":"50","author":"Huang","year":"2009","journal-title":"Compr Psychiatry"},{"issue":"1","key":"joi210137r18","first-page":"1","article-title":"Subsyndromal delirium compared with delirium, dementia, and subjects without delirium or dementia in elderly general hospital admissions and nursing home residents.","volume":"7","author":"Sepulveda","year":"2016","journal-title":"Alzheimers Dement (Amst)"},{"issue":"4","key":"joi210137r19","first-page":"319","article-title":"Epidemiological survey on postoperative delirium in elderly noncardiac surgical patients.","volume":"2","author":"Tan","year":"2011","journal-title":"Med J Peking Union Med Coll Hosp"},{"issue":"1","key":"joi210137r21","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1097\/ANA.0b013e3182712fba","article-title":"BIS-guided anesthesia decreases postoperative delirium and cognitive decline.","volume":"25","author":"Chan","year":"2013","journal-title":"J Neurosurg Anesthesiol"},{"issue":"10","key":"joi210137r22","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2017-016937","article-title":"Comparison of regional with general anaesthesia on postoperative delirium (RAGA-delirium) in the older patients undergoing hip fracture surgery: study protocol for a multicentre randomised controlled trial.","volume":"7","author":"Li","year":"2017","journal-title":"BMJ Open"},{"issue":"1","key":"joi210137r23","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1111\/anae.v75.1","article-title":"The effect of a multidisciplinary care bundle on the incidence of delirium after hip fracture surgery: a quality improvement study.","volume":"75","author":"Chuan","year":"2020","journal-title":"Anaesthesia"},{"issue":"2","key":"joi210137r24","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1176\/jnp.13.2.229","article-title":"Validation of the Delirium Rating Scale-revised-98: comparison with the delirium rating scale and the cognitive test for delirium.","volume":"13","author":"Trzepacz","year":"2001","journal-title":"J Neuropsychiatry Clin Neurosci"},{"issue":"3","key":"joi210137r25","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1111\/anae.12542","article-title":"Outcome by mode of anaesthesia for hip fracture surgery: an observational audit of 65,535 patients in a national dataset.","volume":"69","author":"White","year":"2014","journal-title":"Anaesthesia"},{"issue":"1","key":"joi210137r26","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.bja.2017.11.015","article-title":"The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial.","volume":"120","author":"Coburn","year":"2018","journal-title":"Br J Anaesth"},{"issue":"22","key":"joi210137r27","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1056\/NEJMoa2113514","article-title":"Spinal anesthesia or general anesthesia for hip surgery in older adults.","volume":"385","author":"Neuman","year":"2021","journal-title":"N Engl J Med"},{"issue":"5","key":"joi210137r28","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/j.bja.2017.12.046","article-title":"Postoperative delirium in total knee and hip arthroplasty patients: a study of perioperative modifiable risk factors.","volume":"120","author":"Weinstein","year":"2018","journal-title":"Br J Anaesth"},{"issue":"1","key":"joi210137r29","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/gps.v36.1","article-title":"The risk factors for postoperative delirium in adult patients after hip fracture surgery: a systematic review and meta-analysis.","volume":"36","author":"Wu","year":"2021","journal-title":"Int J Geriatr Psychiatry"},{"issue":"1","key":"joi210137r30","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1186\/s12877-015-0160-7","article-title":"Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics.","volume":"15","author":"Woo","year":"2015","journal-title":"BMC Geriatr"},{"issue":"1","key":"joi210137r31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1001\/jamainternmed.2019.4446","article-title":"Effect of the tailored, family-involved hospital elder life program on postoperative delirium and function in older adults: a randomized clinical trial.","volume":"180","author":"Wang","year":"2020","journal-title":"JAMA Intern Med"},{"issue":"8","key":"joi210137r32","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.1302\/0301-620X.101B8.BJJ-2019-0173.R1","article-title":"Pay for performance and hip fracture outcomes: an interrupted time series and difference-in-differences analysis in England and Scotland.","volume":"101-b","author":"Metcalfe","year":"2019","journal-title":"Bone Joint J"},{"issue":"8","key":"joi210137r33","doi-asserted-by":"publisher","first-page":"1562","DOI":"10.1016\/j.injury.2015.05.004","article-title":"General versus regional anaesthesia for hip fractures: a pilot randomised controlled trial of 322 patients.","volume":"46","author":"Parker","year":"2015","journal-title":"Injury"},{"issue":"5","key":"joi210137r34","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.bjae.2020.02.003","article-title":"Anaesthesia for hip fracture repair.","volume":"20","author":"Shelton","year":"2020","journal-title":"BJA Educ"},{"issue":"1","key":"joi210137r35","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1365-2044.2011.06957.x","article-title":"Management of proximal femoral fractures 2011: Association of Anaesthetists of Great Britain and Ireland.","volume":"67","author":"Griffiths","year":"2012","journal-title":"Anaesthesia"},{"issue":"2","key":"joi210137r38","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/anae.v76.2","article-title":"Guideline for the management of hip fractures 2020: guideline by the Association of Anaesthetists.","volume":"76","author":"Griffiths","year":"2021","journal-title":"Anaesthesia"},{"issue":"7","key":"joi210137r39","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1111\/anae.14225","article-title":"International Fragility Fracture Network Delphi consensus statement on the principles of anaesthesia for patients with hip fracture.","volume":"73","author":"White","year":"2018","journal-title":"Anaesthesia"},{"issue":"5","key":"joi210137r40","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1046\/j.1532-5415.2001.49108.x","article-title":"Reducing delirium after hip fracture: a randomized trial.","volume":"49","author":"Marcantonio","year":"2001","journal-title":"J Am Geriatr Soc"},{"key":"joi210137r15","unstructured":"Official Home of UK Legislation. Medicines for Human Use (Clinical Trials) Regulations 2004. Accessed November 30, 2021.? https:\/\/www.legislation.gov.uk\/uksi\/2004\/1031\/pdfs\/uksi_20041031_en.pdf"},{"key":"joi210137r20","unstructured":"Wang? B, Zhang? QL, Jun? LI, Liu? SY. Risk factors of post-operative delirium and cognitive dysfunction in elderly patients undergoing hip joint replacement surgery. Journal of Clinical Anesthesiology. 2013;29:785\u2013788. Accessed December 15, 2021.? https:\/\/oversea.cnki.net\/KCMS\/detail\/detail.aspx?dbcode=CJFD&dbname=CJFD2013&filename=LCMZ201308028&uniplatform=OVERSEAS_EN&v=WTfrC30ft_WYpCnMQ379p_1AB6d9X0Ii6yytr3rUi2hGGA7dyaDIDB5mCib1N0rE"},{"key":"joi210137r36","unstructured":"National Institute for Health and Care Excellence. Hip fracture: management Published June 22, 2011. Accessed December 12, 2020.? https:\/\/www.nice.org.uk\/guidance\/cg124\/resources\/hip-fracture-management-pdf-35109449902789"},{"key":"joi210137r37","unstructured":"Scottish Intercollegiate Guidelines Network. Management of hip fracture in older people. Published June 2009. Accessed December 12, 2020. https:\/\/pdf4pro.com\/cdn\/part-of-nhs-quality-improvement-scotland-2531e4.pdf"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2787494\/jama_li_2021_oi_210137_1647891846.00805.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T11:02:25Z","timestamp":1647946945000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2787494"}},"subtitle":["The RAGA Randomized Trial"],"short-title":[],"issued":{"date-parts":[[2022,1,4]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,4]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2021.22647","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1,4]]}}}