{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:05:30Z","timestamp":1792112730677,"version":"4.4.0"},"reference-count":153,"publisher":"American Medical Association (AMA)","issue":"19","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2022,11,15]]},"abstract":"<jats:sec id=\"ab-jus220026-1\"><jats:title>Importance<\/jats:title><jats:p>Obstructive sleep apnea (OSA) is associated with adverse health outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-2\"><jats:title>Objective<\/jats:title><jats:p>To review the evidence on screening for OSA in asymptomatic adults or those with unrecognized OSA symptoms to inform the US Preventive Services Task Force.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-3\"><jats:title>Data Sources<\/jats:title><jats:p>PubMed\/MEDLINE, Cochrane Library, Embase, and trial registries through August 23, 2021; surveillance through September 23, 2022.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-4\"><jats:title>Study Selection<\/jats:title><jats:p>English-language studies of screening test accuracy, randomized clinical trials (RCTs) of screening or treatment of OSA reporting health outcomes or harms, and systematic reviews of treatment reporting changes in blood pressure and apnea-hypopnea index (AHI) scores.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-5\"><jats:title>Data Extraction and Synthesis<\/jats:title><jats:p>Dual review of abstracts, full-text articles, and study quality. Meta-analysis of intervention trials.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-6\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Test accuracy, excessive daytime sleepiness, sleep-related and general health\u2013related quality of life (QOL), and harms.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-7\"><jats:title>Results<\/jats:title><jats:p>Eighty-six studies were included (N\u2009=\u200911\u202f051). No study directly compared screening with no screening. Screening accuracy of the Multivariable Apnea Prediction score followed by unattended home sleep testing for detecting severe OSA syndrome (AHI \u226530 and Epworth Sleepiness Scale [ESS] score &amp;amp;gt;10) measured as the area under the curve in 2 studies (n\u2009=\u2009702) was 0.80 (95% CI, 0.78 to 0.82) and 0.83 (95% CI, 0.77 to 0.90). Five studies assessing the accuracy of other screening tools were heterogeneous and results were inconsistent. Compared with inactive control, positive airway pressure was associated with a significant improvement in ESS score from baseline (pooled mean difference, \u22122.33 [95% CI, \u22122.75 to \u22121.90]; 47 trials; n\u2009=\u20097024), sleep-related QOL (standardized mean difference, 0.30 [95% CI, 0.19 to 0.42]; 17 trials; n\u2009=\u20093083), and general health\u2013related QOL measured by the 36-Item Short Form Health Survey (SF-36) mental health component summary score change (pooled mean difference, 2.20 [95% CI, 0.95 to 3.44]; 15 trials; n\u2009=\u20092345) and SF-36 physical health component summary score change (pooled mean difference, 1.53 [95% CI, 0.29 to 2.77]; 13 trials; n\u2009=\u20092031). Use of mandibular advancement devices was also associated with a significantly larger ESS score change compared with controls (pooled mean difference, \u22121.67 [95% CI, 2.09 to \u22121.25]; 10 trials; n\u2009=\u20091540). Reporting of other health outcomes was sparse; no included trial found significant benefit associated with treatment on mortality, cardiovascular events, or motor vehicle crashes. In 3 systematic reviews, positive airway pressure was significantly associated with reduced blood pressure; however, the difference was relatively small (2-3 mm Hg).<\/jats:p><\/jats:sec><jats:sec id=\"ab-jus220026-8\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>The accuracy and clinical utility of OSA screening tools that could be used in primary care settings were uncertain. Positive airway pressure and mandibular advancement devices reduced ESS score. Trials of positive airway pressure found modest improvement in sleep-related and general health\u2013related QOL but have not established whether treatment reduces mortality or improves most other health outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jama.2022.18357","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T16:37:55Z","timestamp":1668530275000},"page":"1951","source":"Crossref","is-referenced-by-count":71,"title":["Screening for Obstructive Sleep Apnea in Adults"],"prefix":"10.1001","volume":"328","author":[{"given":"Cynthia","family":"Feltner","sequence":"first","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Department of Medicine, University of North Carolina at Chapel Hill"},{"name":"Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina F.","family":"Wallace","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"RTI International, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Aymes","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Cook Middleton","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelli L.","family":"Hicks","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manny","family":"Schwimmer","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Department of Internal Medicine, The Ohio State University, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Baker","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey P.","family":"Balio","sequence":"additional","affiliation":[{"name":"Center for Rural Health Research, Department of Health Services Management and Policy, College of Public Health, East Tennessee State University, Johnson City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of North Carolina at Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane E.","family":"Voisin","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Department of Internal Medicine, The Ohio State University, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E.","family":"Jonas","sequence":"additional","affiliation":[{"name":"RTI International\u2013University of North Carolina at Chapel Hill Evidence-based Practice Center"},{"name":"Department of Internal Medicine, The Ohio State University, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"key":"jus220026r1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2147\/NSS","article-title":"Obstructive sleep apnea: current perspectives.","volume":"10","author":"Osman","year":"2018","journal-title":"Nat Sci Sleep"},{"issue":"3","key":"jus220026r2","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1590\/2177-6709.24.3.099-109.sar","article-title":"Obstructive sleep apnea in adults.","volume":"24","author":"Faber","year":"2019","journal-title":"Dental Press J Orthod"},{"issue":"15","key":"jus220026r3","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1056\/NEJMcp1816152","article-title":"Obstructive sleep apnea in adults.","volume":"380","author":"Veasey","year":"2019","journal-title":"N Engl J Med"},{"issue":"8","key":"jus220026r4","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"issue":"9","key":"jus220026r5","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1093\/aje\/kws342","article-title":"Increased prevalence of sleep-disordered breathing in adults.","volume":"177","author":"Peppard","year":"2013","journal-title":"Am J Epidemiol"},{"issue":"3 Pt 1","key":"jus220026r6","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1164\/ajrccm.163.3.9911064","article-title":"Prevalence of sleep-disordered breathing in women: effects of gender.","volume":"163","author":"Bixler","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"jus220026r7","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1164\/ajrccm.157.1.9706079","article-title":"Effects of age on sleep apnea in men, I: prevalence and severity.","volume":"157","author":"Bixler","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"8","key":"jus220026r8","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1001\/archinte.162.8.893","article-title":"Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study.","volume":"162","author":"Young","year":"2002","journal-title":"Arch Intern Med"},{"issue":"1","key":"jus220026r10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.wjorl.2015.08.001","article-title":"Clinical consequences and economic costs of untreated obstructive sleep apnea syndrome.","volume":"1","author":"Knauert","year":"2015","journal-title":"World J Otorhinolaryngol Head Neck Surg"},{"issue":"4","key":"jus220026r11","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1001\/jama.2016.20325","article-title":"Screening for obstructive sleep apnea in adults: US Preventive Services Task Force recommendation statement.","volume":"317","author":"Bibbins-Domingo","year":"2017","journal-title":"JAMA"},{"issue":"8","key":"jus220026r15","doi-asserted-by":"publisher","first-page":"529","DOI":"10.7326\/0003-4819-155-8-201110180-00009","article-title":"QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies.","volume":"155","author":"Whiting","year":"2011","journal-title":"Ann Intern Med"},{"key":"jus220026r16","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/1471-2288-7-10","article-title":"Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews.","volume":"7","author":"Shea","year":"2007","journal-title":"BMC Med Res Methodol"},{"issue":"11","key":"jus220026r19","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/(ISSN)1097-0258","article-title":"Quantifying heterogeneity in a meta-analysis.","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"issue":"7414","key":"jus220026r20","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses.","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"issue":"1, pt 2","key":"jus220026r22","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1111\/jsr.2011.20.issue-1pt2","article-title":"A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea: the Akershus Sleep Apnea Project (ASAP).","volume":"20","author":"Hrubos-Str\u00f8m","year":"2011","journal-title":"J Sleep Res"},{"issue":"11","key":"jus220026r23","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.5665\/sleep.2196","article-title":"In-home, self-assembled sleep studies are useful in diagnosing sleep apnea in the elderly.","volume":"35","author":"Morales","year":"2012","journal-title":"Sleep"},{"issue":"4","key":"jus220026r24","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/jch.12073","article-title":"Screening for severe obstructive sleep apnea syndrome in hypertensive outpatients.","volume":"15","author":"Gurubhagavatula","year":"2013","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"jus220026r25","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/3184382","article-title":"Neck grasp predicts obstructive sleep apnea in type 2 diabetes mellitus.","volume":"2019","author":"Edmonds","year":"2019","journal-title":"Sleep Disord"},{"key":"jus220026r26","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.sleep.2019.01.033","article-title":"The STOP-Bang and Berlin questionnaires to identify obstructive sleep apnoea in Alzheimer\u2019s disease patients.","volume":"57","author":"Jorge","year":"2019","journal-title":"Sleep Med"},{"issue":"1","key":"jus220026r27","doi-asserted-by":"publisher","first-page":"28","DOI":"10.17241\/smr.2020.00808","article-title":"Evaluation of a modified STOP-BANG questionnaire for sleep apnea in adults from the Korean general population.","volume":"12","author":"Shin","year":"2021","journal-title":"Sleep Med Res"},{"issue":"10","key":"jus220026r28","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1136\/rapm-2020-102388","article-title":"Simple screening model for identifying the risk of sleep apnea in patients on opioids for chronic pain.","volume":"46","author":"Selvanathan","year":"2021","journal-title":"Reg Anesth Pain Med"},{"issue":"7","key":"jus220026r29","doi-asserted-by":"publisher","first-page":"485","DOI":"10.7326\/0003-4819-131-7-199910050-00002","article-title":"Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome.","volume":"131","author":"Netzer","year":"1999","journal-title":"Ann Intern Med"},{"issue":"5","key":"jus220026r30","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1097\/ALN.0b013e31816d83e4","article-title":"STOP questionnaire: a tool to screen patients for obstructive sleep apnea.","volume":"108","author":"Chung","year":"2008","journal-title":"Anesthesiology"},{"issue":"5","key":"jus220026r31","doi-asserted-by":"publisher","first-page":"459","DOI":"10.5664\/JCSM.1306","article-title":"The STOP-Bang equivalent model and prediction of severity of obstructive sleep apnea: relation to polysomnographic measurements of the apnea\/hypopnea index.","volume":"7","author":"Farney","year":"2011","journal-title":"J Clin Sleep Med"},{"issue":"3","key":"jus220026r32","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1093\/sleep\/18.3.158","article-title":"A survey screen for prediction of apnea.","volume":"18","author":"Maislin","year":"1995","journal-title":"Sleep"},{"issue":"15","key":"jus220026r33","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1161\/CIRCULATIONAHA.109.849166","article-title":"Cardiovascular risk prediction: basic concepts, current status, and future directions.","volume":"121","author":"Lloyd-Jones","year":"2010","journal-title":"Circulation"},{"key":"jus220026r35","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.smrv.2017.10.004","article-title":"Cardiovascular effects of oral appliance therapy in obstructive sleep apnea: a systematic review and meta-analysis.","volume":"40","author":"de Vries","year":"2018","journal-title":"Sleep Med Rev"},{"key":"jus220026r36","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2021.101446","article-title":"Efficacy of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH): systematic review and meta-analysis.","volume":"58","author":"Labarca","year":"2021","journal-title":"Sleep Med Rev"},{"issue":"2","key":"jus220026r37","doi-asserted-by":"publisher","first-page":"301","DOI":"10.5664\/jcsm.7638","article-title":"Treatment of adult obstructive sleep apnea with positive airway pressure: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.","volume":"15","author":"Patil","year":"2019","journal-title":"J Clin Sleep Med"},{"issue":"10","key":"jus220026r38","doi-asserted-by":"publisher","first-page":"2738","DOI":"10.21037\/jtd","article-title":"Continuous positive airway pressure therapy in non-sleepy patients with obstructive sleep apnea: results of a meta-analysis.","volume":"8","author":"Zhang","year":"2016","journal-title":"J Thorac Dis"},{"issue":"3","key":"jus220026r39","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1161\/CIRCULATIONAHA.104.501841","article-title":"Obstructive sleep apnea syndrome affects left ventricular diastolic function: effects of nasal continuous positive airway pressure in men.","volume":"112","author":"Arias","year":"2005","journal-title":"Circulation"},{"issue":"11","key":"jus220026r40","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.7326\/0003-4819-134-11-200106050-00007","article-title":"Treatment with continuous positive airway pressure is not effective in patients with sleep apnea but no daytime sleepiness: a randomized, controlled trial.","volume":"134","author":"Barb\u00e9","year":"2001","journal-title":"Ann Intern Med"},{"issue":"6","key":"jus220026r41","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1378\/chest.129.6.1459","article-title":"Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: a placebo-controlled trial.","volume":"129","author":"Campos-Rodriguez","year":"2006","journal-title":"Chest"},{"issue":"3","key":"jus220026r42","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1177\/0193945913500567","article-title":"Improving activity in adults with diabetes and coexisting obstructive sleep apnea.","volume":"36","author":"Chasens","year":"2014","journal-title":"West J Nurs Res"},{"issue":"5","key":"jus220026r43","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1111\/(ISSN)1532-5415","article-title":"Continuous positive airway pressure reduces subjective daytime sleepiness in patients with mild to moderate Alzheimer\u2019s disease with sleep disordered breathing.","volume":"54","author":"Chong","year":"2006","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"jus220026r44","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1183\/09031936.00043306","article-title":"Cardiovascular and metabolic effects of CPAP in obese males with OSA.","volume":"29","author":"Coughlin","year":"2007","journal-title":"Eur Respir J"},{"key":"jus220026r45","doi-asserted-by":"publisher","first-page":"c5991","DOI":"10.1136\/bmj.c5991","article-title":"Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial.","volume":"341","author":"Dur\u00e1n-Cantolla","year":"2010","journal-title":"BMJ"},{"issue":"6","key":"jus220026r46","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.sleep.2007.06.018","article-title":"Cardiac function after CPAP therapy in patients with chronic heart failure and sleep apnea: a multicenter study.","volume":"9","author":"Egea","year":"2008","journal-title":"Sleep Med"},{"issue":"4","key":"jus220026r47","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s11325-007-0115-0","article-title":"Effect of a 2 week CPAP treatment on mood states in patients with obstructive sleep apnea: a double-blind trial.","volume":"11","author":"Haensel","year":"2007","journal-title":"Sleep Breath"},{"issue":"12","key":"jus220026r48","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1136\/thoraxjnl-2011-201420","article-title":"Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study.","volume":"67","author":"Hoyos","year":"2012","journal-title":"Thorax"},{"issue":"12","key":"jus220026r49","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1136\/thx.2006.064063","article-title":"Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness.","volume":"61","author":"Hui","year":"2006","journal-title":"Thorax"},{"issue":"9170","key":"jus220026r50","doi-asserted-by":"publisher","first-page":"2100","DOI":"10.1016\/S0140-6736(98)10532-9","article-title":"Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial.","volume":"353","author":"Jenkinson","year":"1999","journal-title":"Lancet"},{"issue":"3","key":"jus220026r51","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1136\/thorax.55.3.224","article-title":"Randomised prospective parallel trial of therapeutic versus subtherapeutic nasal continuous positive airway pressure on simulated steering performance in patients with obstructive sleep apnoea.","volume":"55","author":"Hack","year":"2000","journal-title":"Thorax"},{"issue":"12","key":"jus220026r52","doi-asserted-by":"publisher","first-page":"1260","DOI":"10.1016\/j.sleep.2013.08.786","article-title":"The effect of continuous positive airway pressure therapy on arterial stiffness and endothelial function in obstructive sleep apnea: a randomized controlled trial in patients without cardiovascular disease.","volume":"14","author":"Jones","year":"2013","journal-title":"Sleep Med"},{"issue":"12","key":"jus220026r53","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.5665\/sleep.2226","article-title":"Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: the Apnea Positive Pressure Long-term Efficacy Study (APPLES).","volume":"35","author":"Kushida","year":"2012","journal-title":"Sleep"},{"issue":"6","key":"jus220026r54","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1111\/jsr.12430","article-title":"Impact of continuous positive airway pressure (CPAP) on quality of life in patients with obstructive sleep apnea (OSA).","volume":"25","author":"Batool-Anwar","year":"2016","journal-title":"J Sleep Res"},{"issue":"1","key":"jus220026r55","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1183\/09031936.00047709","article-title":"A randomised controlled trial of nasal continuous positive airway pressure on insulin sensitivity in obstructive sleep apnoea.","volume":"35","author":"Lam","year":"2010","journal-title":"Eur Respir J"},{"issue":"4","key":"jus220026r56","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.ddmod.2011.10.001","article-title":"A model for studying neuropsychological effects of sleep intervention: the effect of 3-week continuous positive airway pressure treatment.","volume":"8","author":"Lee","year":"2011","journal-title":"Drug Discov Today Dis Models"},{"issue":"4","key":"jus220026r57","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1093\/sleep\/29.4.564","article-title":"Effect of continuous positive airway pressure versus supplemental oxygen on sleep quality in obstructive sleep apnea: a placebo-CPAP-controlled study.","volume":"29","author":"Loredo","year":"2006","journal-title":"Sleep"},{"issue":"5","key":"jus220026r58","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1136\/thx.2004.032078","article-title":"Randomised controlled crossover trial of humidified continuous positive airway pressure in mild obstructive sleep apnoea.","volume":"60","author":"Marshall","year":"2005","journal-title":"Thorax"},{"issue":"4","key":"jus220026r59","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1210\/jc.2017-02389","article-title":"Randomized trial of CPAP and vardenafil on erectile and arterial function in men with obstructive sleep apnea and erectile dysfunction.","volume":"103","author":"Melehan","year":"2018","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"jus220026r60","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1164\/ajrccm.164.4.2006034","article-title":"Effectiveness of CPAP treatment in daytime function in sleep apnea syndrome: a randomized controlled study with an optimized placebo.","volume":"164","author":"Montserrat","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"jus220026r61","doi-asserted-by":"publisher","first-page":"177","DOI":"10.5665\/sleep.3332","article-title":"Continuous positive airway pressure improves sleep and daytime sleepiness in patients with Parkinson disease and sleep apnea.","volume":"37","author":"Neikrug","year":"2014","journal-title":"Sleep"},{"key":"jus220026r62","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/1532-429X-12-50","article-title":"Nasal continuous positive airway pressure improves myocardial perfusion reserve and endothelial-dependent vasodilation in patients with obstructive sleep apnea.","volume":"12","author":"Nguyen","year":"2010","journal-title":"J Cardiovasc Magn Reson"},{"issue":"9302","key":"jus220026r63","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/S0140-6736(02)07445-7","article-title":"Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial.","volume":"359","author":"Pepperell","year":"2002","journal-title":"Lancet"},{"issue":"6","key":"jus220026r64","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1183\/09031936.00026608","article-title":"CPAP and measures of cardiovascular risk in males with OSAS.","volume":"32","author":"Kohler","year":"2008","journal-title":"Eur Respir J"},{"issue":"3","key":"jus220026r65","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1164\/rccm.201102-0316OC","article-title":"Continuous positive airway pressure reduces postprandial lipidemia in obstructive sleep apnea: a randomized, placebo-controlled crossover trial.","volume":"184","author":"Phillips","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"jus220026r66","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1183\/09031936.06.00062805","article-title":"Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients.","volume":"27","author":"Robinson","year":"2006","journal-title":"Eur Respir J"},{"issue":"11","key":"jus220026r67","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1093\/sleep\/31.11.1551","article-title":"Effects of continuous positive airway pressure on quality of life in patients with moderate to severe obstructive sleep apnea: data from a randomized controlled trial.","volume":"31","author":"Siccoli","year":"2008","journal-title":"Sleep"},{"issue":"10","key":"jus220026r68","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1093\/eurheartj\/ehm131","article-title":"Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial.","volume":"28","author":"Smith","year":"2007","journal-title":"Eur Heart J"},{"issue":"7","key":"jus220026r69","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1164\/rccm.201202-0200OC","article-title":"Continuous positive airway pressure treatment of sleepy patients with milder obstructive sleep apnea: results of the CPAP Apnea Trial North American Program (CATNAP) randomized clinical trial.","volume":"186","author":"Weaver","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"jus220026r70","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1136\/thx.2006.074351","article-title":"Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetes.","volume":"62","author":"West","year":"2007","journal-title":"Thorax"},{"issue":"9","key":"jus220026r71","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1016\/j.sleep.2008.11.007","article-title":"The effect of continuous positive airway pressure treatment on physical activity in patients with obstructive sleep apnoea: a randomised controlled trial.","volume":"10","author":"West","year":"2009","journal-title":"Sleep Med"},{"issue":"2","key":"jus220026r72","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1164\/ajrccm.159.2.9804061","article-title":"Evidence of the effectiveness of continuous positive airway pressure in the treatment of sleep apnea\/hypopnea syndrome.","volume":"159","author":"Ballester","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"jus220026r73","doi-asserted-by":"publisher","DOI":"10.1002\/edm2.v4.2","article-title":"Effect of 12-week continuous positive airway pressure therapy on glucose levels assessed by continuous glucose monitoring in people with type 2 diabetes and obstructive sleep apnoea: a randomized controlled trial.","volume":"4","author":"Bangh\u00f8j","year":"2020","journal-title":"Endocrinol Diabetes Metab"},{"issue":"7","key":"jus220026r74","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1164\/rccm.200901-0050OC","article-title":"Long-term effect of continuous positive airway pressure in hypertensive patients with sleep apnea.","volume":"181","author":"Barb\u00e9","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"issue":"20","key":"jus220026r75","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1001\/jama.2012.4366","article-title":"Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial.","volume":"307","author":"Barb\u00e9","year":"2012","journal-title":"JAMA"},{"issue":"6","key":"jus220026r76","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1164\/rccm.200311-1571OC","article-title":"Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea.","volume":"170","author":"Barnes","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"jus220026r77","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1164\/rccm.201602-0265OC","article-title":"Continuous positive airway pressure improves quality of life in women with obstructive sleep apnea: a randomized controlled trial.","volume":"194","author":"Campos-Rodriguez","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"jus220026r78","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1136\/thoraxjnl-2012-202178","article-title":"Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial.","volume":"67","author":"Craig","year":"2012","journal-title":"Thorax"},{"issue":"5","key":"jus220026r79","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1378\/chest.15-0171","article-title":"Effect of CPAP on cognition, brain function, and structure among elderly patients with OSA: a randomized pilot study.","volume":"148","author":"Dalmases","year":"2015","journal-title":"Chest"},{"issue":"8897","key":"jus220026r80","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/S0140-6736(94)91522-9","article-title":"Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea\/hypopnoea syndrome.","volume":"343","author":"Engleman","year":"1994","journal-title":"Lancet"},{"issue":"2","key":"jus220026r81","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1136\/thx.52.2.114","article-title":"Effect of CPAP therapy on daytime function in patients with mild sleep apnoea\/hypopnoea syndrome.","volume":"52","author":"Engleman","year":"1997","journal-title":"Thorax"},{"issue":"5","key":"jus220026r82","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1136\/thx.53.5.341","article-title":"Randomised placebo controlled trial of daytime function after continuous positive airway pressure (CPAP) therapy for the sleep apnoea\/hypopnoea syndrome.","volume":"53","author":"Engleman","year":"1998","journal-title":"Thorax"},{"issue":"2","key":"jus220026r83","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1164\/ajrccm.159.2.9803121","article-title":"Randomized placebo-controlled crossover trial of continuous positive airway pressure for mild sleep apnea\/hypopnea syndrome.","volume":"159","author":"Engleman","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"jus220026r84","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1164\/ajrccm.163.2.2005037","article-title":"Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome.","volume":"163","author":"Faccenda","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"24","key":"jus220026r85","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1056\/NEJMoa1306766","article-title":"CPAP versus oxygen in obstructive sleep apnea.","volume":"370","author":"Gottlieb","year":"2014","journal-title":"N Engl J Med"},{"key":"jus220026r86","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.ahj.2017.03.001","article-title":"Impact of continuous positive airway pressure and oxygen on health status in patients with coronary heart disease, cardiovascular risk factors, and obstructive sleep apnea: a Heart Biomarker Evaluation in Apnea Treatment (HEARTBEAT) analysis.","volume":"189","author":"Lewis","year":"2017","journal-title":"Am Heart J"},{"issue":"5","key":"jus220026r87","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1002\/da.v38.5","article-title":"Does continuous positive airways pressure treatment improve clinical depression in obstructive sleep apnea? a randomized wait-list controlled study.","volume":"38","author":"Jackson","year":"2021","journal-title":"Depress Anxiety"},{"key":"jus220026r88","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.sleep.2019.03.011","article-title":"Clinical depression in untreated obstructive sleep apnea: examining predictors and a meta-analysis of prevalence rates.","volume":"62","author":"Jackson","year":"2019","journal-title":"Sleep Med"},{"issue":"4","key":"jus220026r89","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1136\/thx.2006.063644","article-title":"Randomised study of three non-surgical treatments in mild to moderate obstructive sleep apnoea.","volume":"62","author":"Lam","year":"2007","journal-title":"Thorax"},{"issue":"4","key":"jus220026r90","doi-asserted-by":"publisher","first-page":"380","DOI":"10.5664\/jcsm.26860","article-title":"Neuropsychological effects of 2-week continuous positive airway pressure treatment and supplemental oxygen in patients with obstructive sleep apnea: a randomized placebo-controlled study.","volume":"3","author":"Lim","year":"2007","journal-title":"J Clin Sleep Med"},{"issue":"3","key":"jus220026r91","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1007\/s11325-019-01893-5","article-title":"Circulating adipocyte fatty acid-binding protein is reduced by continuous positive airway pressure treatment for obstructive sleep apnea\u2014a randomized controlled study.","volume":"24","author":"Lui","year":"2020","journal-title":"Sleep Breath"},{"issue":"22","key":"jus220026r92","doi-asserted-by":"publisher","first-page":"2407","DOI":"10.1001\/jama.2013.281250","article-title":"Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial.","volume":"310","author":"Mart\u00ednez-Garc\u00eda","year":"2013","journal-title":"JAMA"},{"issue":"1","key":"jus220026r93","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1183\/09031936.00064214","article-title":"Obstructive sleep apnoea in the elderly: role of continuous positive airway pressure treatment.","volume":"46","author":"Mart\u00ednez-Garc\u00eda","year":"2015","journal-title":"Eur Respir J"},{"issue":"1","key":"jus220026r94","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1164\/rccm.201410-1900OC","article-title":"Efficacy of different treatment alternatives for obesity hypoventilation syndrome: Pickwick Study.","volume":"192","author":"Masa","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"8 Pt 1","key":"jus220026r95","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1164\/ajrccm.164.8.2008146","article-title":"Effect of continuous positive airway pressure on sleep architecture in the sleep apnea-hypopnea syndrome: a randomized controlled trial.","volume":"164","author":"McArdle","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"jus220026r96","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/S2213-2600(14)70172-9","article-title":"Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial.","volume":"2","author":"McMillan","year":"2014","journal-title":"Lancet Respir Med"},{"issue":"5","key":"jus220026r97","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1164\/rccm.201601-0088OC","article-title":"Effect of positive airway pressure on cardiovascular outcomes in coronary artery disease patients with nonsleepy obstructive sleep apnea: the RICCADSA randomized controlled trial.","volume":"194","author":"Peker","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"jus220026r98","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1513\/AnnalsATS.201803-174OC","article-title":"Continuous positive airway pressure treatment and depression in adults with coronary artery disease and nonsleepy obstructive sleep apnea: a secondary analysis of the RICCADSA Trial.","volume":"16","author":"Balcan","year":"2019","journal-title":"Ann Am Thorac Soc"},{"key":"jus220026r99","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.sleep.2020.11.034","article-title":"Continuous positive airway pressure treatment and anxiety in adults with coronary artery disease and nonsleepy obstructive sleep apnea in the RICCADSA trial.","volume":"77","author":"Celik","year":"2021","journal-title":"Sleep Med"},{"issue":"2","key":"jus220026r100","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00518-2019","article-title":"The role of CPAP treatment in elderly patients with moderate obstructive sleep apnoea: a multicentre randomised controlled trial.","volume":"54","author":"Ponce","year":"2019","journal-title":"Eur Respir J"},{"issue":"3, pt 1","key":"jus220026r101","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1164\/ajrccm.157.3.9709042","article-title":"Improvement of mild sleep-disordered breathing with CPAP compared with conservative therapy.","volume":"157","author":"Redline","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"jus220026r102","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1097\/HJH.0b013e3282fb81ed","article-title":"Sustained effect of continuous positive airway pressure on baroreflex sensitivity in congestive heart failure patients with obstructive sleep apnea.","volume":"26","author":"Ruttanaumpawan","year":"2008","journal-title":"J Hypertens"},{"issue":"13","key":"jus220026r103","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1056\/NEJMoa022479","article-title":"Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea.","volume":"348","author":"Kaneko","year":"2003","journal-title":"N Engl J Med"},{"issue":"1","key":"jus220026r104","doi-asserted-by":"publisher","first-page":"35","DOI":"10.5665\/sleep.5312","article-title":"A randomized controlled trial of continuous positive airway pressure on glucose tolerance in obese patients with obstructive sleep apnea.","volume":"39","author":"Salord","year":"2016","journal-title":"Sleep"},{"issue":"4","key":"jus220026r105","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1164\/rccm.201511-2260OC","article-title":"The effect of treatment of obstructive sleep apnea on glycemic control in type 2 diabetes.","volume":"194","author":"Shaw","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"jus220026r106","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1093\/sleep\/34.1.121","article-title":"Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial.","volume":"34","author":"Tomfohr","year":"2011","journal-title":"Sleep"},{"issue":"4","key":"jus220026r107","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/S2213-2600(19)30402-3","article-title":"Continuous positive airway pressure versus standard care for the treatment of people with mild obstructive sleep apnoea (MERGE): a multicentre, randomised controlled trial.","volume":"8","author":"Wimms","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"4","key":"jus220026r108","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsx040","article-title":"Effect of continuous positive airway pressure treatment on health-related quality of life and sleepiness in high cardiovascular risk individuals with sleep apnea: Best Apnea Interventions for Research (BestAIR) trial.","volume":"40","author":"Zhao","year":"2017","journal-title":"Sleep"},{"issue":"11","key":"jus220026r109","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1111\/resp.13363","article-title":"Continuous positive airway pressure for obstructive sleep apnoea does not improve asthma control.","volume":"23","author":"Ng","year":"2018","journal-title":"Respirology"},{"issue":"7","key":"jus220026r110","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.3390\/diagnostics11071176","article-title":"Association of excessive daytime sleepiness with the Zung self-rated depression subscales in adults with coronary artery disease and obstructive sleep apnea.","volume":"11","author":"Celik","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"5","key":"jus220026r111","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1164\/rccm.202011-4133OC","article-title":"Effect of continuous positive airway pressure on arrhythmia in atrial fibrillation and sleep apnea: a randomized controlled trial.","volume":"204","author":"Traaen","year":"2021","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"jus220026r112","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.5664\/jcsm.7926","article-title":"CPAP and health-related quality of life in adults with coronary artery disease and nonsleepy obstructive sleep apnea in the RICCADSA trial.","volume":"15","author":"Wallstr\u00f6m","year":"2019","journal-title":"J Clin Sleep Med"},{"issue":"5","key":"jus220026r113","doi-asserted-by":"publisher","first-page":"617","DOI":"10.5665\/sleep.1816","article-title":"A controlled trial of CPAP therapy on metabolic control in individuals with impaired glucose tolerance and sleep apnea.","volume":"35","author":"Weinstock","year":"2012","journal-title":"Sleep"},{"issue":"7","key":"jus220026r114","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1164\/rccm.201704-0672LE","article-title":"The Epworth Sleepiness Scale: minimum clinically important difference in obstructive sleep apnea.","volume":"197","author":"Patel","year":"2018","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"jus220026r115","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1136\/thoraxjnl-2018-211959","article-title":"Minimum important difference of the Epworth Sleepiness Scale in obstructive sleep apnoea: estimation from three randomised controlled trials.","volume":"74","author":"Crook","year":"2019","journal-title":"Thorax"},{"issue":"6","key":"jus220026r116","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36), I: conceptual framework and item selection.","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care"},{"issue":"2","key":"jus220026r117","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1111\/hesr.2005.40.issue-2","article-title":"A comparison of clinically important differences in health-related quality of life for patients with chronic lung disease, asthma, or heart disease.","volume":"40","author":"Wyrwich","year":"2005","journal-title":"Health Serv Res"},{"key":"jus220026r118","doi-asserted-by":"publisher","first-page":"A227","DOI":"10.1093\/sleep\/zsy061.611","article-title":"Using multiple anchor-based and distribution-based estimates to determine the Minimal Important Difference (MID) for the FOSQ-10.","volume":"41","author":"Weaver","year":"2018","journal-title":"Sleep"},{"issue":"2","key":"jus220026r119","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1164\/ajrccm.158.2.9712036","article-title":"Development of a disease-specific health-related quality of life questionnaire for sleep apnea.","volume":"158","author":"Flemons","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"jus220026r120","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1159\/000319595","article-title":"Oral appliance therapy versus nasal continuous positive airway pressure in obstructive sleep apnea: a randomized, placebo-controlled trial.","volume":"81","author":"Aarab","year":"2011","journal-title":"Respiration"},{"issue":"4","key":"jus220026r121","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1002\/cre2.v6.4","article-title":"Oral appliance therapy versus nasal continuous positive airway pressure in obstructive sleep apnea: a randomized, placebo-controlled trial on temporomandibular side-effects.","volume":"6","author":"Nikolopoulou","year":"2020","journal-title":"Clin Exp Dent Res"},{"issue":"2","key":"jus220026r122","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s11325-012-0746-7","article-title":"Effects of treatment with oral appliance on 24-h blood pressure in patients with obstructive sleep apnea and hypertension: a randomized clinical trial.","volume":"17","author":"Andr\u00e9n","year":"2013","journal-title":"Sleep Breath"},{"issue":"1","key":"jus220026r123","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1164\/ajrccm.162.1.9908112","article-title":"A randomized, controlled crossover trial of two oral appliances for sleep apnea treatment.","volume":"162","author":"Bloch","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"jus220026r124","doi-asserted-by":"publisher","first-page":"e605","DOI":"10.4317\/medoral.20649","article-title":"Efficacy of mandibular advancement device in the treatment of obstructive sleep apnea syndrome: a randomized controlled crossover clinical trial.","volume":"20","author":"Dur\u00e1n-Cantolla","year":"2015","journal-title":"Med Oral Patol Oral Cir Bucal"},{"issue":"4","key":"jus220026r125","doi-asserted-by":"publisher","first-page":"374","DOI":"10.5664\/jcsm.26365","article-title":"Effect of oral appliance therapy on neurobehavioral functioning in obstructive sleep apnea: a randomized controlled trial.","volume":"1","author":"Naismith","year":"2005","journal-title":"J Clin Sleep Med"},{"issue":"5","key":"jus220026r126","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1164\/rccm.200203-208OC","article-title":"Oral appliance therapy improves symptoms in obstructive sleep apnea: a randomized, controlled trial.","volume":"166","author":"Gotsopoulos","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"jus220026r127","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1093\/sleep\/27.5.934","article-title":"Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial.","volume":"27","author":"Gotsopoulos","year":"2004","journal-title":"Sleep"},{"issue":"3","key":"jus220026r128","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1093\/ejo\/24.3.251","article-title":"Mandibular advancement appliances and obstructive sleep apnoea: a randomized clinical trial.","volume":"24","author":"Johnston","year":"2002","journal-title":"Eur J Orthod"},{"issue":"10","key":"jus220026r129","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1136\/thoraxjnl-2014-205464","article-title":"A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO).","volume":"69","author":"Quinnell","year":"2014","journal-title":"Thorax"},{"issue":"9","key":"jus220026r130","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1164\/rccm.201609-1817OC","article-title":"Impact of mandibular advancement therapy on endothelial function in severe obstructive sleep apnea.","volume":"195","author":"Gagnadoux","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"8","key":"jus220026r131","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1001\/jamainternmed.2015.2051","article-title":"Oral appliance therapy in patients with daytime sleepiness and snoring or mild to moderate sleep apnea: a randomized clinical trial.","volume":"175","author":"Marklund","year":"2015","journal-title":"JAMA Intern Med"},{"issue":"2","key":"jus220026r132","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1111\/j.1365-2869.2008.00645.x","article-title":"Mandibular advancement appliance for obstructive sleep apnoea: results of a randomised placebo controlled trial using parallel group design.","volume":"17","author":"Petri","year":"2008","journal-title":"J Sleep Res"},{"issue":"8","key":"jus220026r133","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1212\/01.wnl.0000323927.13250.54","article-title":"Treating obstructive sleep apnea in adults with epilepsy: a randomized pilot trial.","volume":"71","author":"Malow","year":"2008","journal-title":"Neurology"},{"issue":"1","key":"jus220026r135","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1002\/(ISSN)1097-0258","article-title":"Spectrum bias: a quantitative and graphical analysis of the variability of medical diagnostic test performance.","volume":"23","author":"Goehring","year":"2004","journal-title":"Stat Med"},{"issue":"7","key":"jus220026r136","doi-asserted-by":"publisher","first-page":"598","DOI":"10.7326\/0003-4819-137-7-200210010-00011","article-title":"Spectrum bias or spectrum effect? subgroup variation in diagnostic test evaluation.","volume":"137","author":"Mulherin","year":"2002","journal-title":"Ann Intern Med"},{"issue":"5","key":"jus220026r137","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1136\/ebm.13.5.132","article-title":"Spectrum bias: why generalists and specialists do not connect.","volume":"13","author":"Jelinek","year":"2008","journal-title":"Evid Based Med"},{"issue":"2","key":"jus220026r138","doi-asserted-by":"publisher","first-page":"135","DOI":"10.7326\/0003-4819-117-2-135","article-title":"Spectrum bias in the evaluation of diagnostic tests: lessons from the rapid dipstick test for urinary tract infection.","volume":"117","author":"Lachs","year":"1992","journal-title":"Ann Intern Med"},{"issue":"5","key":"jus220026r139","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1093\/fampra\/cmn051","article-title":"Spectrum bias\u2014why clinicians need to be cautious when applying diagnostic test studies.","volume":"25","author":"Willis","year":"2008","journal-title":"Fam Pract"},{"issue":"7","key":"jus220026r140","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1001\/jama.2013.276185","article-title":"Does this patient have obstructive sleep apnea?: the Rational Clinical Examination systematic review.","volume":"310","author":"Myers","year":"2013","journal-title":"JAMA"},{"issue":"3","key":"jus220026r141","doi-asserted-by":"publisher","first-page":"210","DOI":"10.7326\/M12-3187","article-title":"Diagnosis of obstructive sleep apnea in adults: a clinical practice guideline from theAmerican College of Physicians.","volume":"161","author":"Qaseem","year":"2014","journal-title":"Ann Intern Med"},{"issue":"10","key":"jus220026r142","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1093\/sleep\/20.10.844","article-title":"Daytime sleepiness and sleep habits of Australian workers.","volume":"20","author":"Johns","year":"1997","journal-title":"Sleep"},{"issue":"1","key":"jus220026r143","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1046\/j.1365-2869.2000.00177.x","article-title":"Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth Sleepiness Scale: failure of the MSLT as a gold standard.","volume":"9","author":"Johns","year":"2000","journal-title":"J Sleep Res"},{"issue":"1","key":"jus220026r144","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1002\/(ISSN)1531-8249","article-title":"Randomized trial of modafinil for the treatment of pathological somnolence in narcolepsy.","volume":"43","author":"US Modafinil in Narcolepsy Multicenter Study Group","year":"1998","journal-title":"Ann Neurol"},{"issue":"4","key":"jus220026r145","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1164\/ajrccm.163.4.2005036","article-title":"Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea\/hypopnea syndrome.","volume":"163","author":"Kingshott","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"7536","key":"jus220026r146","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1136\/bmj.38705.470590.55","article-title":"Didgeridoo playing as alternative treatment for obstructive sleep apnoea syndrome: randomised controlled trial.","volume":"332","author":"Puhan","year":"2006","journal-title":"BMJ"},{"issue":"5","key":"jus220026r147","first-page":"1","article-title":"Oral appliances for obstructive sleep apnea: an evidence-based analysis.","volume":"9","author":"Medical Advisory Secretariat","year":"2009","journal-title":"Ont Health Technol Assess Ser"},{"issue":"3","key":"jus220026r148","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/S1389-9457(03)00031-5","article-title":"Measurement properties of the Epworth Sleepiness Scale.","volume":"4","author":"Miletin","year":"2003","journal-title":"Sleep Med"},{"issue":"7","key":"jus220026r149","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.sleep.2007.08.004","article-title":"Confirmatory factor analysis of the Epworth Sleepiness Scale (ESS) in patients with obstructive sleep apnoea.","volume":"9","author":"Smith","year":"2008","journal-title":"Sleep Med"},{"issue":"21","key":"jus220026r150","doi-asserted-by":"publisher","first-page":"2216","DOI":"10.1001\/jama.2014.5180","article-title":"Resistant hypertension: a review of diagnosis and management.","volume":"311","author":"Vongpatanasin","year":"2014","journal-title":"JAMA"},{"issue":"7","key":"jus220026r151","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/j.jacc.2011.06.008","article-title":"Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial.","volume":"58","author":"Bisognano","year":"2011","journal-title":"J Am Coll Cardiol"},{"issue":"9756","key":"jus220026r152","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1016\/S0140-6736(10)62039-9","article-title":"Renal sympathetic denervation in patients with treatment-resistant hypertension (the Symplicity HTN-2 trial): a randomised controlled trial.","volume":"376","author":"Esler","year":"2010","journal-title":"Lancet"},{"issue":"19","key":"jus220026r153","doi-asserted-by":"publisher","first-page":"2560","DOI":"10.1001\/jama.289.19.2560","article-title":"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.","volume":"289","author":"Chobanian","year":"2003","journal-title":"JAMA"},{"key":"jus220026r9","volume-title":"Diagnosis and Treatment of Obstructive Sleep Apnea in Adults","author":"Balk","year":"2011"},{"key":"jus220026r13","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2022.18357","volume-title":"Screening for Obstructive Sleep Apnea in Adults: an Evidence Review for the US Preventive Services Task Force. Evidence Synthesis No. 220","author":"Feltner","year":"2022"},{"key":"jus220026r14","volume-title":"Human Development Report 2020: The Next Frontier: Human Development and the Anthropocene","year":"2020"},{"key":"jus220026r18","author":"StataCorp","year":"2019"},{"key":"jus220026r34","doi-asserted-by":"crossref","DOI":"10.1002\/0471722146","volume-title":"Applied Logistic Regression","author":"Hosmer","year":"2000"},{"key":"jus220026r12","unstructured":"US Preventive Services Task Force. US Preventive Services Task Force Procedure Manual. Updated May 2021. Accessed October 11, 2022. https:\/\/www.uspreventiveservicestaskforce.org\/uspstf\/procedure-manual"},{"key":"jus220026r17","unstructured":"West? SL, Gartlehner? G, Mansfield? AJ, . Comparative Effectiveness Review Methods: Clinical Heterogeneity. Report 10-EHC070-EF. Agency for Healthcare Research and Quality. Published 2010. Accessed October 11, 2022. https:\/\/pubmed.ncbi.nlm.nih.gov\/21433337\/"},{"key":"jus220026r21","unstructured":"Higgins? J, Thomas? J, Chandler? J, . Cochrane Handbook for Systematic Reviews of Interventions. Version 6.3. Cochrane. Published 2022. Accessed October 11, 2022. https:\/\/training.cochrane.org\/handbook"},{"key":"jus220026r134","unstructured":"Redline? S. Effects of treatment of sleep apnea on metabolic syndrome. [NCT01385995]. 2014. Accessed October 11, 2022. https:\/\/www.clinicaltrials.gov\/show\/NCT01385995"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2798400\/jama_feltner_2022_us_220026_1667853280.20864.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,12]],"date-time":"2023-03-12T04:23:33Z","timestamp":1678595013000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2798400"}},"subtitle":["Updated Evidence Report and Systematic Review for the US Preventive Services Task Force"],"short-title":[],"issued":{"date-parts":[[2022,11,15]]},"references-count":153,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2022,11,15]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2022.18357","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,15]]}}}