{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:35:36Z","timestamp":1792510536987,"version":"4.5.0"},"reference-count":21,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2023,3,21]]},"abstract":"<jats:sec><jats:title>Importance<\/jats:title><jats:p>It is unknown whether ivermectin, with a maximum targeted dose of 600 \u03bcg\/kg, shortens symptom duration or prevents hospitalization among outpatients with mild to moderate COVID-19.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effectiveness of ivermectin at a maximum targeted dose of 600 \u03bcg\/kg daily for 6 days, compared with placebo, for the treatment of early mild to moderate COVID-19.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>The ongoing Accelerating COVID-19 Therapeutic Interventions and Vaccines 6 (ACTIV-6) platform randomized clinical trial was designed to evaluate repurposed therapies among outpatients with mild to moderate COVID-19. A total of 1432 participants older than 30 years with confirmed COVID-19 experiencing at least 2 symptoms of acute infection for less than or equal to 7 days were enrolled at 93 sites in the US from February 16, 2022, through July 22, 2022, with follow-up data through November 10, 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Participants were randomly assigned to receive ivermectin, with a maximum targeted dose of 600 \u03bcg\/kg (n\u2009=\u2009708) daily, or placebo (n\u2009=\u2009724) for 6 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>The primary outcome was time to sustained recovery, defined as at least 3 consecutive days without symptoms. The 7 secondary outcomes included a composite of hospitalization, death, or urgent\/emergent care utilization by day 28.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 1432 randomized participants who received study medication or placebo, the median (IQR) age was 48 (38-58) years, 854 (59.6%) were women, and 1188 (83.1%) reported receiving at least 2 SARS-CoV-2 vaccine doses. The median (IQR) time to sustained recovery was 11 (11-12) days in the ivermectin group and 12 (11-12) days in the placebo group. The hazard ratio for improvement in time to recovery was 1.02 (95% credible interval, 0.92-1.12; <jats:italic>P<\/jats:italic>\u2009value for efficacy =\u2009.65). Among those receiving ivermectin, 39 (5.5%) were hospitalized, died, or had urgent or emergency care visits compared with 42 (5.8%) receiving placebo (hazard ratio, 0.97 [95% credible interval, 0.60-1.45]; <jats:italic>P<\/jats:italic>\u2009=\u2009.55). In the ivermectin group, 1 participant died and 6 were hospitalized (1.0%); 2 participants (0.3%) were hospitalized in the placebo group and there were no deaths. Adverse events were uncommon in both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Among outpatients with mild to moderate COVID-19, treatment with ivermectin, with a maximum targeted dose of 600 \u03bcg\/kg daily for 6 days, compared with placebo did not improve time to sustained recovery. These findings do not support the use of ivermectin in patients with mild to moderate COVID-19.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration<\/jats:title><jats:p>ClinicalTrials.gov Identifier: <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04885530\">NCT04885530<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1001\/jama.2023.1650","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T16:01:05Z","timestamp":1676908865000},"page":"888","source":"Crossref","is-referenced-by-count":81,"title":["Effect of Higher-Dose Ivermectin for 6 Days vs Placebo on Time to Sustained Recovery in Outpatients With COVID-19"],"prefix":"10.1001","volume":"329","author":[{"given":"Susanna","family":"Naggie","sequence":"first","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"},{"name":"Department of Medicine, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Boulware","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Medicine, University of Minnesota, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Lindsell","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Stewart","sequence":"additional","affiliation":[{"name":"School of Data Science, University of Virginia, Charlottesville"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex J.","family":"Slandzicki","sequence":"additional","affiliation":[{"name":"Clinical Trials Center of Middle Tennessee, Franklin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen C.","family":"Lim","sequence":"additional","affiliation":[{"name":"University Medical Center New Orleans, Louisiana State University Health Sciences Center, New Orleans"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Cohen","sequence":"additional","affiliation":[{"name":"Jadestone Clinical Research, LLC, Silver Spring, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kavtaradze","sequence":"additional","affiliation":[{"name":"David Kavtaradze, Inc, Cordele, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arch P.","family":"Amon","sequence":"additional","affiliation":[{"name":"Lakeland Regional Medical Center, Lakeland, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahab","family":"Gabriel","sequence":"additional","affiliation":[{"name":"Focus Clinical Research Solutions, Charlotte, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Gentile","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Michael","family":"Felker","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"},{"name":"Department of Medicine, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dushyantha","family":"Jayaweera","sequence":"additional","affiliation":[{"name":"Department of Medicine, Miller School of Medicine, University of Miami, Miami, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew W.","family":"McCarthy","sequence":"additional","affiliation":[{"name":"Weill Cornell Medicine, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Sulkowski","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Johns Hopkins University, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell L.","family":"Rothman","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybil","family":"Wilson","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"DeLong","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"April","family":"Remaly","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhonda","family":"Wilder","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Collins","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, Tennessee"},{"name":"Veterans Affairs Tennessee Valley Healthcare System, Geriatric Research, Education and Clinical Center (GRECC), Nashville"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Dunsmore","sequence":"additional","affiliation":[{"name":"National Center for Advancing Translational Sciences, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey J.","family":"Adam","sequence":"additional","affiliation":[{"name":"Foundation for the National Institutes of Health, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Thicklin","sequence":"additional","affiliation":[{"name":"Stakeholder Advisory Committee, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George J.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Biomedical Advanced Research and Development Authority, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adit A.","family":"Ginde","sequence":"additional","affiliation":[{"name":"University of Colorado School of Medicine, Aurora"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Castro","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care and Sleep Medicine, University of Missouri-Kansas City School of Medicine, Kansas City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"McTigue","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Shenkman","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes & Biomedical Informatics, College of Medicine, University of Florida, Gainesville"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian F.","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina"},{"name":"Department of Medicine, Duke University School of Medicine, Durham, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William (Kelly)","family":"Vincent","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raina","family":"Vincent","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Bianchi","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jen","family":"Premas","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Cordero-Loperena","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Rivera","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhu","family":"Gupta","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Karawan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carey","family":"Ziomek","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Arena","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonaly","family":"DeAlmeida","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soroush","family":"Ramin","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya","family":"Nataraj","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Paasche-Orlow","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Henault","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Waite","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Miller","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginger","family":"Brounce","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"George-Adebayo","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeolu","family":"Adebayo","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Wallan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Vogel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Munoz","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Watson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Singleton","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Rivon","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Sevier","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold","family":"Del Pilar","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Spangler","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohail","family":"Rao","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Cantu","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind","family":"Krishna","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Evans","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tylene","family":"Falkner","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandi","family":"Kerr","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Spees","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mailyn","family":"Marta","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Harrington","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rowena","family":"Dolor","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madison","family":"Frazier","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorraine","family":"Vergara","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Wilson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valencia","family":"Burruss","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri","family":"Hurst","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igho","family":"Ofotokun","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Rebolledo","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Prabhu","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krystal","family":"Klicka","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Lightfeather","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki","family":"James","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella","family":"Rogers","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Parihar","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De'Ambra","family":"Torress","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chukwuemeka","family":"Oragwu","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngozi","family":"Oguego","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Pillai","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Juma","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad","family":"Ghaly","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dafer","family":"Al-Haddadin","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney","family":"Ramirez","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gammal","family":"Hassanien","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samah","family":"Ismail","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Meltzer","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seamus","family":"Moran","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Brehaut","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelina","family":"Roche","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha","family":"Mehta","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Koppinger","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Baez","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivone","family":"Pagan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dallal","family":"Abdelsayed","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Aziz","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Robinson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Nguyen","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Pardue","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Hammons","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Ruiz-Unger","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Reyes","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Cienki","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisselle","family":"Jimenez","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Wong","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yuan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Li","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Szeto","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Stelmash","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Haight","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deryl","family":"Lamb","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amron","family":"Harper","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Pyram-Bernard","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlen","family":"Quintero","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eftim","family":"Adhami","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josette","family":"Maria","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diksha","family":"Paudel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana","family":"Raymond","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Summers","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy","family":"Turner","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Lenert","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Gallegos","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth Ann","family":"Szwast","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahsan","family":"Abdulghani","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pravin","family":"Vasoya","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conrad","family":"Miller","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawa","family":"Wiley","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirav","family":"Shah","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tovah","family":"Klein","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Castex","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Feliciano","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Olivo","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Ghaly","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainub","family":"Javed","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Nawrocki","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Vecchiarelli","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikki","family":"Vigil","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijaya","family":"Cherukuri","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Burden","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Linn","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Fisher","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Patel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praksha","family":"Patel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuti","family":"Patel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Ellison","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Harrison","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binod","family":"Shah","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugata","family":"Shah","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upinder","family":"Singh","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Donahue","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Jazayeri","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Gupta","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Chandrasekar","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Moritz","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tabitha","family":"Fortt","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anisa","family":"Fortt","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Jones-Ince","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alix","family":"McKee","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christy","family":"Schattinger","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Wilson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Farlow","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lillian","family":"Finlaw","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall","family":"Richwine","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tearani","family":"Williams","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penny","family":"Paizer","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Carson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Michelson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Austin","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangeeta","family":"Khetpal","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"Cantrell","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drew","family":"Franklin","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karissa","family":"Marshall","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind","family":"Mahadevan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelyn","family":"Rosequist","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Gnoni","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal","family":"Daffner","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"VandeWeerd","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Roberts","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"D'Andrea","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Swink","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Powers-Fletcher","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvere","family":"Mukunzi","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Hensley","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittney","family":"Manning","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Isache","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Bowman","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelique","family":"Callaghan-Brown","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Scott","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"Schwasinger-Schmidt","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashlie","family":"Cornejo","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Almanzar","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letty","family":"Ginsburg","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Americo","family":"Hajaz","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Bramante","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Robinson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Seithel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Sekikawa","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Klawson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Ostrosky","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Umana","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Patterson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Tragus","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Jackson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Hallowell","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Haughey","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavna","family":"Vaidya-Tank","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Gould","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Goyal","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carly","family":"Gatewood","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Williamson","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Seagle","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Salsgiver","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddie","family":"Armas","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jhonsai","family":"Cheng","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priscilla","family":"Huerta","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Garcia-Diaz","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Aamodt","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JaMario","family":"Ayers","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jess","family":"Collins","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Graves","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Grindstaff","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Lai","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itzel","family":"Lopez","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Marlin","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Merkel","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Nwosu","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Savannah","family":"Obregon","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Orozco","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoli","family":"Perez-Torres","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Prato","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Ratcliff","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Rhode","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Shirey-Rice","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krista","family":"Vermillion","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsi-Nien","family":"Tan","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seibert","family":"Tregoning","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meghan","family":"Vance","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber","family":"Vongsamphanh","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Weir","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Zaleski","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Bozzette","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gene","family":"Passamani","sequence":"additional","affiliation":[{"name":"for the Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV)-6 Study Group and Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"6","key":"joi230017r1","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1056\/NEJMoa2116044","article-title":"Molnupiravir for oral treatment of COVID-19 in nonhospitalized patients.","volume":"386","author":"Jayk Bernal","year":"2022","journal-title":"N Engl J Med"},{"issue":"22","key":"joi230017r2","doi-asserted-by":"publisher","first-page":"2292","DOI":"10.1001\/jama.2020.22760","article-title":"Fluvoxamine vs placebo and clinical deterioration in outpatients with symptomatic COVID-19: a randomized clinical trial.","volume":"324","author":"Lenze","year":"2020","journal-title":"JAMA"},{"issue":"1","key":"joi230017r3","doi-asserted-by":"publisher","first-page":"e42","DOI":"10.1016\/S2214-109X(21)00448-4","article-title":"Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial.","volume":"10","author":"Reis","year":"2022","journal-title":"Lancet Glob Health"},{"issue":"10303","key":"joi230017r4","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/S0140-6736(21)01744-X","article-title":"Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.","volume":"398","author":"Yu","year":"2021","journal-title":"Lancet"},{"issue":"14","key":"joi230017r5","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1001\/jama.2021.3071","article-title":"Effect of ivermectin on time to resolution of symptoms among adults with mild COVID-19: a randomized clinical trial.","volume":"325","author":"L\u00f3pez-Medina","year":"2021","journal-title":"JAMA"},{"issue":"7","key":"joi230017r6","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1056\/NEJMoa2201662","article-title":"Randomized trial of metformin, ivermectin, and fluvoxamine for Covid-19.","volume":"387","author":"Bramante","year":"2022","journal-title":"N Engl J Med"},{"issue":"4","key":"joi230017r7","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1001\/jama.2022.24100","article-title":"Effect of fluvoxamine vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19: a randomized clinical trial.","volume":"329","author":"McCarthy","year":"2023","journal-title":"JAMA"},{"key":"joi230017r11","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2020.104787","article-title":"The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro.","volume":"178","author":"Caly","year":"2020","journal-title":"Antiviral Res"},{"issue":"6","key":"joi230017r12","doi-asserted-by":"publisher","first-page":"e286","DOI":"10.1016\/S2589-7500(20)30086-8","article-title":"A real-time dashboard of clinical trials for COVID-19.","volume":"2","author":"Thorlund","year":"2020","journal-title":"Lancet Digit Health"},{"issue":"2","key":"joi230017r13","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab645","article-title":"Ivermectin for COVID-19: addressing potential bias and medical fraud.","volume":"9","author":"Hill","year":"2022","journal-title":"Open Forum Infect Dis"},{"issue":"2","key":"joi230017r15","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1177\/0885066620973585","article-title":"Retracted article: Clinical and scientific rationale for the \u201cMATH+\u201d hospital treatment protocol for COVID-19.","volume":"36","author":"Kory","year":"2021","journal-title":"J Intensive Care Med"},{"issue":"16","key":"joi230017r16","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1001\/jama.2022.18590","article-title":"Effect of ivermectin vs placebo on time to sustained recovery in outpatients with mild to moderate COVID-19: a randomized clinical trial.","volume":"328","author":"Naggie","year":"2022","journal-title":"JAMA"},{"issue":"18","key":"joi230017r17","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1056\/NEJMoa2115869","article-title":"Effect of early treatment with ivermectin among patients with Covid-19.","volume":"386","author":"Reis","year":"2022","journal-title":"N Engl J Med"},{"key":"joi230017r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100959","article-title":"Antiviral effect of high-dose ivermectin in adults with COVID-19: a proof-of-concept randomized trial.","volume":"37","author":"Krolewiecki","year":"2021","journal-title":"EClinicalMedicine"},{"key":"joi230017r19","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.101119","article-title":"Corrigendum to antiviral effect of high-dose ivermectin in adults with COVID-19: a proof-of-concept randomized trial [EClinicalMedicine 37 (2021) 100,959]\u201d.","volume":"39","author":"Krolewiecki","year":"2021","journal-title":"EClinicalMedicine"},{"key":"joi230017r8","unstructured":"COVID-19 Treatment Guidelines Panel. Coronavirus disease 2019 (COVID-19) treatment guidelines. National Institutes of Health. Accessed December 14, 2022. https:\/\/www.covid19treatmentguidelines.nih.gov\/"},{"key":"joi230017r9","unstructured":"Bhimraj? A, Morgan? RL, Shumaker? AH, . IDSA Guidelines on the Treatment and Management of Patients With COVID-19. Infectious Diseases Society of America; 2022. Accessed December 14, 2022. https:\/\/www.idsociety.org\/practice-guideline\/covid-19-guideline-treatment-and-management\/"},{"key":"joi230017r10","unstructured":"Therapeutics and COVID-19: Living Guideline. World Health Organization; 2022. Accessed December 14, 2022. https:\/\/app.magicapp.org\/#\/guideline\/nBkO1E"},{"key":"joi230017r14","unstructured":"Elgazzar A. Efficacy and safety of ivermectin for treatment and prophylaxis of COVID-19 pandemic. Research Square. Preprint posted July 14, 2021. Accessed June 8, 2022. https:\/\/www.researchsquare.com\/article\/rs-100956\/v4"},{"key":"joi230017r20","unstructured":"R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing. Accessed September 19, 2022. https:\/\/www.R-project.org\/"},{"key":"joi230017r21","doi-asserted-by":"crossref","unstructured":"Schilling? WHK, Jittamala? P, Watson? JA, . Pharmacometric assessment of the in vivo antiviral activity of ivermectin in early symptomatic COVID-19.? medRxiv. Preprint posted July 19, 2022. doi:10.1101\/2022.07.15.22277570","DOI":"10.1101\/2022.07.15.22277570"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2801827\/jama_naggie_2023_oi_230017_1715808904.28699.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T15:02:48Z","timestamp":1715871768000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2801827"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2023,3,21]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,3,21]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2023.1650","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,21]]}}}