{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T09:09:05Z","timestamp":1793264945850,"version":"4.5.0"},"reference-count":73,"publisher":"American Medical Association (AMA)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2023,9,26]]},"abstract":"<jats:sec id=\"ab-jrv230016-1\"><jats:title>Importance<\/jats:title><jats:p>An estimated 15\u202f000 children and adolescents aged 0 to 19 years are diagnosed with cancer each year in the US, and more than 85% survive for at least 5 years. By 45 years of age, approximately 95% of people who survive childhood cancer will develop a significant health problem related to the childhood cancer diagnosis or its treatment.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jrv230016-2\"><jats:title>Observations<\/jats:title><jats:p>Approximately 500\u202f000 people currently alive in the US have survived childhood cancer. The most common severe or life-threatening chronic health problems related to childhood cancer or its treatment are endocrine disorders such as hypothyroidism or growth hormone deficiency (44%), subsequent neoplasms such as breast cancer or thyroid cancer (7%), and cardiovascular disease such as cardiomyopathy or congestive heart failure, coronary artery disease, and cerebrovascular disease (5.3%). Medical conditions related to a cancer diagnosis during childhood or adolescence are most commonly caused by the radiation therapy and the chemotherapies used to treat cancer and may develop at varying lengths of time after exposure to these treatments. Individuals at highest risk for developing treatment-related health problems include patients with brain cancer treated with cranial irradiation (approximately 70% develop severe or life-threatening health problems) and allogeneic hematopoietic stem cell transplant recipients (approximately 60% develop severe or life-threatening health problems). Individuals at the lowest risk for developing treatment-related health problems include those who survived solid tumors (such as Wilms tumor) treated with surgical resection alone or with minimal chemotherapy, for whom the prevalence of subsequent health problems is similar to people who did not have cancer during childhood or adolescence. People diagnosed with childhood cancer in the 1990s who survived for at least 5 years after the cancer diagnosis have a shorter lifespan (by about 9 years) vs children who were not diagnosed with cancer in the 1990s.<\/jats:p><\/jats:sec><jats:sec id=\"ab-jrv230016-3\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Approximately 500\u202f000 individuals currently alive in the US have survived childhood cancer. The most common adverse effects in individuals who survived childhood cancer are endocrine disorders, subsequent neoplasms, and cardiovascular disease. There is a need for clinicians and patients to have heightened awareness of these complications.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jama.2023.16875","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T15:01:30Z","timestamp":1695740490000},"page":"1175","source":"Crossref","is-referenced-by-count":86,"title":["Clinical Care for People Who Survive Childhood Cancer"],"prefix":"10.1001","volume":"330","author":[{"given":"Smita","family":"Bhatia","sequence":"first","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, Heersink School of Medicine, University of Alabama at Birmingham"},{"name":"Department of Pediatrics, Division of Pediatric Hematology\/Oncology, Heersink School of Medicine, University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Tonorezos","sequence":"additional","affiliation":[{"name":"Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Landier","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, Heersink School of Medicine, University of Alabama at Birmingham"},{"name":"Department of Pediatrics, Division of Pediatric Hematology\/Oncology, Heersink School of Medicine, University of Alabama at Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"10112","key":"jrv230016r2","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1016\/S0140-6736(17)31610-0","article-title":"The cumulative burden of surviving childhood cancer.","volume":"390","author":"Bhakta","year":"2017","journal-title":"Lancet"},{"key":"jrv230016r3","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djad115","article-title":"Counts, incidence rates, and trends of pediatric cancer in the United States, 2003-2019.","author":"Siegel","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"jrv230016r4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3322\/caac.v73.1","article-title":"Cancer statistics, 2023.","volume":"73","author":"Siegel","year":"2023","journal-title":"CA Cancer J Clin"},{"issue":"3","key":"jrv230016r5","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1001\/jamaoncol.2019.5582","article-title":"Life expectancy of adult survivors of childhood cancer over 3 decades.","volume":"6","author":"Yeh","year":"2020","journal-title":"JAMA Oncol"},{"issue":"7","key":"jrv230016r6","doi-asserted-by":"publisher","first-page":"444","DOI":"10.7326\/0003-4819-152-7-201004060-00009","article-title":"Systematic review.","volume":"152","author":"Henderson","year":"2010","journal-title":"Ann Intern Med"},{"issue":"13","key":"jrv230016r7","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1200\/JCO.2011.34.8987","article-title":"Anthracycline-related cardiomyopathy after childhood cancer.","volume":"30","author":"Blanco","year":"2012","journal-title":"J Clin Oncol"},{"issue":"4","key":"jrv230016r8","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1634\/theoncologist.2012-0239","article-title":"Association of anthracycline-related cardiac histological lesions with NADPH oxidase functional polymorphisms.","volume":"18","author":"Cascales","year":"2013","journal-title":"Oncologist"},{"issue":"27","key":"jrv230016r10","doi-asserted-by":"publisher","first-page":"3240","DOI":"10.1200\/JCO.2016.66.6545","article-title":"Endocrine abnormalities in aging survivors of childhood cancer.","volume":"34","author":"Mostoufi-Moab","year":"2016","journal-title":"J Clin Oncol"},{"issue":"13","key":"jrv230016r11","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1093\/jnci\/djj243","article-title":"Premature menopause in survivors of childhood cancer.","volume":"98","author":"Sklar","year":"2006","journal-title":"J Natl Cancer Inst"},{"issue":"7","key":"jrv230016r12","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.ctrv.2009.06.004","article-title":"Prevalence and risk factors of radiation-induced growth hormone deficiency in childhood cancer survivors.","volume":"35","author":"Mulder","year":"2009","journal-title":"Cancer Treat Rev"},{"issue":"9","key":"jrv230016r13","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1016\/S1470-2045(13)70251-1","article-title":"Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer.","volume":"14","author":"Barton","year":"2013","journal-title":"Lancet Oncol"},{"issue":"5","key":"jrv230016r14","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/S1470-2045(16)00086-3","article-title":"Pregnancy after chemotherapy in male and female survivors of childhood cancer treated between 1970 and 1999.","volume":"17","author":"Chow","year":"2016","journal-title":"Lancet Oncol"},{"issue":"6","key":"jrv230016r15","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1007\/s00432-020-03193-y","article-title":"Pregnancy, time to pregnancy and obstetric outcomes among female childhood cancer survivors.","volume":"146","author":"van Dijk","year":"2020","journal-title":"J Cancer Res Clin Oncol"},{"issue":"11","key":"jrv230016r16","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1016\/S1470-2045(14)70408-5","article-title":"Cumulative alkylating agent exposure and semen parameters in adult survivors of childhood cancer.","volume":"15","author":"Green","year":"2014","journal-title":"Lancet Oncol"},{"issue":"12","key":"jrv230016r17","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1111\/aogs.v98.12","article-title":"Adverse obstetric outcomes among female childhood and adolescent cancer survivors in Sweden.","volume":"98","author":"Armuand","year":"2019","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"jrv230016r18","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1038\/s41585-021-00523-8","article-title":"Fertility preservation in boys facing gonadotoxic cancer therapy.","volume":"19","author":"Jensen","year":"2022","journal-title":"Nat Rev Urol"},{"issue":"2","key":"jrv230016r19","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1016\/S1470-2045(20)30594-5","article-title":"Fertility preservation for female patients with childhood, adolescent, and young adult cancer.","volume":"22","author":"Mulder","year":"2021","journal-title":"Lancet Oncol"},{"issue":"20","key":"jrv230016r20","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1200\/JCO.2016.71.6902","article-title":"Long-term risk of subsequent malignant neoplasms after treatment of childhood cancer in the DCOG LATER study cohort.","volume":"35","author":"Teepen","year":"2017","journal-title":"J Clin Oncol"},{"issue":"8","key":"jrv230016r21","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1001\/jama.2017.0693","article-title":"Temporal trends in treatment and subsequent neoplasm risk among 5-year survivors of childhood cancer, 1970-2015.","volume":"317","author":"Turcotte","year":"2017","journal-title":"JAMA"},{"issue":"34","key":"jrv230016r23","doi-asserted-by":"publisher","first-page":"3310","DOI":"10.1200\/JCO.19.00129","article-title":"Chemotherapy and risk of subsequent malignant neoplasms in the Childhood Cancer Survivor Study cohort.","volume":"37","author":"Turcotte","year":"2019","journal-title":"J Clin Oncol"},{"issue":"8","key":"jrv230016r24","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1093\/jnci\/djy212","article-title":"Long-term risk of skin cancer among childhood cancer survivors.","volume":"111","author":"Teepen","year":"2019","journal-title":"J Natl Cancer Inst"},{"issue":"16","key":"jrv230016r25","doi-asserted-by":"publisher","first-page":"3733","DOI":"10.1200\/JCO.2005.06.237","article-title":"Nonmelanoma skin cancer in survivors of childhood and adolescent cancer.","volume":"23","author":"Perkins","year":"2005","journal-title":"J Clin Oncol"},{"issue":"3","key":"jrv230016r26","doi-asserted-by":"publisher","first-page":"237","DOI":"10.6004\/jnccn.2018.7096","article-title":"Nonmelanoma skin cancer in childhood and young adult cancer survivors previously treated with radiotherapy.","volume":"17","author":"Thorsness","year":"2019","journal-title":"J Natl Compr Canc Netw"},{"issue":"16","key":"jrv230016r27","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1093\/jnci\/djs298","article-title":"Radiation-related risk of basal cell carcinoma.","volume":"104","author":"Watt","year":"2012","journal-title":"J Natl Cancer Inst"},{"issue":"24","key":"jrv230016r28","doi-asserted-by":"publisher","first-page":"4979","DOI":"10.1200\/JCO.2004.11.032","article-title":"Development of risk-based guidelines for pediatric cancer survivors.","volume":"22","author":"Landier","year":"2004","journal-title":"J Clin Oncol"},{"issue":"12","key":"jrv230016r29","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1001\/jamaoncol.2022.4649","article-title":"Association of changes in cancer therapy over 3 decades with risk of subsequent breast cancer among female childhood cancer survivors.","volume":"8","author":"Henderson","year":"2022","journal-title":"JAMA Oncol"},{"issue":"21","key":"jrv230016r30","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.1200\/JCO.2013.54.4601","article-title":"Breast cancer after chest radiation therapy for childhood cancer.","volume":"32","author":"Moskowitz","year":"2014","journal-title":"J Clin Oncol"},{"issue":"24","key":"jrv230016r31","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1200\/JCO.18.02219","article-title":"Mortality after breast cancer among survivors of childhood cancer.","volume":"37","author":"Moskowitz","year":"2019","journal-title":"J Clin Oncol"},{"issue":"9","key":"jrv230016r32","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1200\/JCO.2015.62.3314","article-title":"Breast cancer risk in childhood cancer survivors without a history of chest radiotherapy.","volume":"34","author":"Henderson","year":"2016","journal-title":"J Clin Oncol"},{"issue":"19","key":"jrv230016r33","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1200\/JCO.18.01099","article-title":"Subsequent breast cancer in female childhood cancer survivors in the St Jude Lifetime Cohort Study (SJLIFE).","volume":"37","author":"Ehrhardt","year":"2019","journal-title":"J Clin Oncol"},{"issue":"24","key":"jrv230016r34","doi-asserted-by":"publisher","first-page":"3901","DOI":"10.1200\/JCO.2008.20.7738","article-title":"Radiation dose and breast cancer risk in the Childhood Cancer Survivor Study.","volume":"27","author":"Inskip","year":"2009","journal-title":"J Clin Oncol"},{"issue":"4","key":"jrv230016r35","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1158\/1078-0432.CCR-20-3609","article-title":"A randomized phase IIb study of low-dose tamoxifen in chest-irradiated cancer survivors at risk for breast cancer.","volume":"27","author":"Bhatia","year":"2021","journal-title":"Clin Cancer Res"},{"issue":"10","key":"jrv230016r36","doi-asserted-by":"publisher","first-page":"2400","DOI":"10.1002\/ijc.v125:10","article-title":"Risk of thyroid cancer in survivors of childhood cancer.","volume":"125","author":"Taylor","year":"2009","journal-title":"Int J Cancer"},{"issue":"9476","key":"jrv230016r37","doi-asserted-by":"publisher","first-page":"2014","DOI":"10.1016\/S0140-6736(05)66695-0","article-title":"Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study).","volume":"365","author":"Sigurdson","year":"2005","journal-title":"Lancet"},{"issue":"3","key":"jrv230016r38","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1093\/neuonc\/noy124","article-title":"Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort.","volume":"21","author":"Kok","year":"2019","journal-title":"Neuro Oncol"},{"issue":"14","key":"jrv230016r39","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1200\/JCO.2016.70.1896","article-title":"Morbidity and mortality associated with meningioma after cranial radiotherapy.","volume":"35","author":"Bowers","year":"2017","journal-title":"J Clin Oncol"},{"issue":"6","key":"jrv230016r40","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1093\/jnci\/djx235","article-title":"Risk of soft-tissue sarcoma among 69 460 five-year survivors of childhood cancer in Europe.","volume":"110","author":"Bright","year":"2018","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"jrv230016r41","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.ijrobp.2011.11.022","article-title":"Risk factors associated with secondary sarcomas in childhood cancer survivors.","volume":"84","author":"Henderson","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"11","key":"jrv230016r42","doi-asserted-by":"publisher","first-page":"757","DOI":"10.7326\/0003-4819-156-11-201206050-00002","article-title":"Secondary gastrointestinal cancer in childhood cancer survivors.","volume":"156","author":"Henderson","year":"2012","journal-title":"Ann Intern Med"},{"issue":"20","key":"jrv230016r43","doi-asserted-by":"publisher","first-page":"2552","DOI":"10.1200\/JCO.2011.37.8760","article-title":"Secondary colorectal carcinoma after childhood cancer.","volume":"30","author":"Nottage","year":"2012","journal-title":"J Clin Oncol"},{"key":"jrv230016r44","doi-asserted-by":"publisher","first-page":"b4606","DOI":"10.1136\/bmj.b4606","article-title":"Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer.","volume":"339","author":"Mulrooney","year":"2009","journal-title":"BMJ"},{"issue":"6","key":"jrv230016r45","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1093\/annonc\/mdf167","article-title":"Frequency and risk factors of subclinical cardiotoxicity after anthracycline therapy in children.","volume":"13","author":"Kremer","year":"2002","journal-title":"Ann Oncol"},{"issue":"14","key":"jrv230016r46","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1001\/archinternmed.2010.233","article-title":"Cardiac function in 5-year survivors of childhood cancer.","volume":"170","author":"van der Pal","year":"2010","journal-title":"Arch Intern Med"},{"key":"jrv230016r47","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ejca.2021.06.021","article-title":"Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors.","volume":"156","author":"van Dalen","year":"2021","journal-title":"Eur J Cancer"},{"issue":"4","key":"jrv230016r48","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1016\/j.ijrobp.2013.03.034","article-title":"Radiation, atherosclerotic risk factors, and stroke risk in survivors of pediatric cancer.","volume":"86","author":"Mueller","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"12","key":"jrv230016r49","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.121.024735","article-title":"Underdiagnosis and undertreatment of modifiable cardiovascular risk factors among survivors of childhood cancer.","volume":"11","author":"Chow","year":"2022","journal-title":"J Am Heart Assoc"},{"issue":"29","key":"jrv230016r50","doi-asserted-by":"publisher","first-page":"3673","DOI":"10.1200\/JCO.2013.49.3205","article-title":"Modifiable risk factors and major cardiac events among adult survivors of childhood cancer.","volume":"31","author":"Armstrong","year":"2013","journal-title":"J Clin Oncol"},{"issue":"8","key":"jrv230016r51","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1016\/j.apmr.2013.03.009","article-title":"Chemotherapy-related neuropathic symptoms and functional impairment in adult survivors of extracranial solid tumors of childhood.","volume":"94","author":"Ness","year":"2013","journal-title":"Arch Phys Med Rehabil"},{"issue":"4","key":"jrv230016r52","doi-asserted-by":"publisher","first-page":"249","DOI":"10.2174\/1573400510666141114223827","article-title":"A systematic review of selected musculoskeletal late effects in survivors of childhood cancer.","volume":"10","author":"Gawade","year":"2014","journal-title":"Curr Pediatr Rev"},{"issue":"1","key":"jrv230016r53","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S2213-8587(22)00286-8","article-title":"Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER).","volume":"11","author":"van Atteveld","year":"2023","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"2","key":"jrv230016r54","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1159\/000494809","article-title":"Skeletal morbidity in children and adolescents during and following cancer therapy.","volume":"91","author":"Mostoufi-Moab","year":"2019","journal-title":"Horm Res Paediatr"},{"issue":"16","key":"jrv230016r55","doi-asserted-by":"publisher","first-page":"2940","DOI":"10.1158\/0008-5472.CAN-22-0418","article-title":"Leveraging therapy-specific polygenic risk scores to predict restrictive lung defects in childhood cancer survivors.","volume":"82","author":"Im","year":"2022","journal-title":"Cancer Res"},{"issue":"4","key":"jrv230016r56","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1667\/RR14276.1","article-title":"The risk of cataract among survivors of childhood and adolescent cancer.","volume":"185","author":"Chodick","year":"2016","journal-title":"Radiat Res"},{"key":"jrv230016r57","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.ejca.2016.09.023","article-title":"Determinants of ototoxicity in 451 platinum-treated Dutch survivors of childhood cancer.","volume":"69","author":"Clemens","year":"2016","journal-title":"Eur J Cancer"},{"issue":"11","key":"jrv230016r58","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1200\/JCO.2015.63.6738","article-title":"Hearing loss in patients who received cranial radiation therapy for childhood cancer.","volume":"34","author":"Bass","year":"2016","journal-title":"J Clin Oncol"},{"issue":"11","key":"jrv230016r59","doi-asserted-by":"publisher","first-page":"2559","DOI":"10.1002\/cncr.25797","article-title":"Fatigue, vitality, sleep, and neurocognitive functioning in adult survivors of childhood cancer.","volume":"117","author":"Clanton","year":"2011","journal-title":"Cancer"},{"issue":"4","key":"jrv230016r60","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1093\/jnci\/djx224","article-title":"Chronic health conditions and neurocognitive function in aging survivors of childhood cancer.","volume":"110","author":"Cheung","year":"2018","journal-title":"J Natl Cancer Inst"},{"issue":"10","key":"jrv230016r61","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1001\/jamaoncol.2019.1094","article-title":"Association between anesthesia exposure and neurocognitive and neuroimaging outcomes in long-term survivors of childhood acute lymphoblastic leukemia.","volume":"5","author":"Banerjee","year":"2019","journal-title":"JAMA Oncol"},{"issue":"3","key":"jrv230016r62","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1002\/cncr.v126.3","article-title":"Physical fitness and neurocognitive outcomes in adult survivors of childhood acute lymphoblastic leukemia.","volume":"126","author":"Phillips","year":"2020","journal-title":"Cancer"},{"issue":"1","key":"jrv230016r63","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/cncr.v128.1","article-title":"Seizures\u2019 impact on cognition and quality of life in childhood cancer survivors.","volume":"128","author":"Phillips","year":"2022","journal-title":"Cancer"},{"issue":"18","key":"jrv230016r64","doi-asserted-by":"publisher","first-page":"2041","DOI":"10.1200\/JCO.19.02677","article-title":"Consistent physical activity and future neurocognitive problems in adult survivors of childhood cancers.","volume":"38","author":"Barlow-Krelina","year":"2020","journal-title":"J Clin Oncol"},{"issue":"4","key":"jrv230016r65","doi-asserted-by":"publisher","first-page":"e184","DOI":"10.1016\/S1470-2045(21)00750-6","article-title":"Recommendations for the surveillance of mental health problems in childhood, adolescent, and young adult cancer survivors.","volume":"23","author":"Marchak","year":"2022","journal-title":"Lancet Oncol"},{"issue":"6","key":"jrv230016r66","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-1878","article-title":"National trends in the prevalence and treatment of depression in adolescents and young adults.","volume":"138","author":"Mojtabai","year":"2016","journal-title":"Pediatrics"},{"issue":"3","key":"jrv230016r68","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1002\/cncr.v128.3","article-title":"Risk of suicide among individuals with a history of childhood cancer.","volume":"128","author":"Barnes","year":"2022","journal-title":"Cancer"},{"issue":"30","key":"jrv230016r69","doi-asserted-by":"publisher","first-page":"3474","DOI":"10.1200\/JCO.2016.71.7066","article-title":"Financial burden in survivors of childhood cancer.","volume":"35","author":"Nipp","year":"2017","journal-title":"J Clin Oncol"},{"issue":"4","key":"jrv230016r70","doi-asserted-by":"publisher","first-page":"208","DOI":"10.3322\/canjclin.54.4.208","article-title":"Long-term complications following childhood and adolescent cancer.","volume":"54","author":"Oeffinger","year":"2004","journal-title":"CA Cancer J Clin"},{"issue":"4","key":"jrv230016r71","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1002\/pbc.24445","article-title":"A worldwide collaboration to harmonize guidelines for the long-term follow-up of childhood and young adult cancer survivors.","volume":"60","author":"Kremer","year":"2013","journal-title":"Pediatr Blood Cancer"},{"issue":"5","key":"jrv230016r72","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1634\/theoncologist.2018-0103","article-title":"The role of primary care physicians in childhood cancer survivorship care.","volume":"24","author":"Signorelli","year":"2019","journal-title":"Oncologist"},{"issue":"21","key":"jrv230016r73","doi-asserted-by":"publisher","first-page":"3864","DOI":"10.1002\/cncr.v125.21","article-title":"Providing health care for patients with childhood cancer and survivors.","volume":"125","author":"Wadhwa","year":"2019","journal-title":"Cancer"},{"key":"jrv230016r1","unstructured":"Surveillance, Epidemiology, and End Results Program, National Cancer Institute. SEER Cancer Statistics Review 1975-2018. Posted April 15, 2021. Accessed July 22, 2023. https:\/\/seer.cancer.gov\/csr\/1975_2018\/"},{"key":"jrv230016r9","unstructured":"Children\u2019s Oncology Group. Long-term follow-up guidelines for survivors of childhood, adolescent, and young adult cancers: version 5.0 (October 2018). Accessed August 29, 2023. http:\/\/www.survivorshipguidelines.org"},{"key":"jrv230016r22","unstructured":"Childhood Cancer Survivor Study. Overall CCSS cohort demographic and treatment exposure tables. Accessed July 22, 2023. https:\/\/ccss.stjude.org\/public-access-data\/treatment-exposure-tables.html"},{"key":"jrv230016r67","unstructured":"Harvard Medical School. Table 2: 12-month prevalence of DSM-IV\/WMH-CIDI disorders by sex and cohort in the National Comorbidity Survey. Accessed August 7, 2023. https:\/\/www.hcp.med.harvard.edu\/ncs\/ftpdir\/table_ncsr_12monthprevgenderxage.pdf"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2809804\/jama_bhatia_2023_rv_230016_1695046163.50998.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T15:01:35Z","timestamp":1695740495000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2809804"}},"subtitle":["A Review"],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":73,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2023,9,26]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2023.16875","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9,26]]}}}