{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:46:06Z","timestamp":1792449966174,"version":"4.5.0"},"reference-count":56,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2026,1,6]]},"abstract":"\n Importance<\/jats:title>\n The Dietary Approaches to Stop Hypertension (DASH) eating plan lowered blood pressure (BP) among Black adults in a controlled environment, but to date, there are no grocery shopping strategies that replicated its health effects in a community setting.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The Groceries for Black Residents of Boston to Stop Hypertension (GoFresh) trial was conducted to determine the effects of low sodium-DASH groceries on systolic BP.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This parallel-group randomized clinical trial was conducted in Boston from August 2022 to September 2025 among Black residents of urban communities with few grocery stores, a systolic BP of 120 to less than 150 mm Hg, a diastolic BP less than 100 mm Hg, and no hypertension treatment. Data were analyzed from June through October 2025.<\/jats:p>\n <\/jats:sec>\n \n Interventions<\/jats:title>\n Participants were randomly assigned to 12 weeks of home-delivered, DASH-patterned groceries ordered weekly with dietitian counseling without emphasizing cost or three $500 stipends every 4 weeks intended for self-directed grocery shopping.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n \n The primary comparison was the difference in the 3-month change in model-estimated office systolic BP (based on 3 measurements over at least 2 visits) between interventions. Adherence was assessed via 24-hour urine collection. Secondary outcomes included diastolic BP, body mass index (BMI), hemoglobin A\n \n 1\n c<\/jats:sc>\n <\/jats:sub>\n levels, and low-density lipoprotein (LDL) cholesterol. Maintenance of effects was assessed 3 months after intervention cessation.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 180 participants, (mean [SD] age, 46.1 [13.3] years; 102 female [56.7%]; 180 self-reported Black [100%]; 12 Hispanic [6.7%]), 175 individuals (97.2%) completed the primary outcome assessment. Mean (SD) baseline systolic BP and diastolic BP were 130.0 (6.7) mm Hg and 79.8 (8.1) mm Hg. At 3 months, the mean systolic BP changed \u22125.7 mm Hg (95% CI, \u22127.4, to\u22123.9 mm Hg) in the DASH-patterned group and \u22122.3 mm Hg (95% CI, \u22124.1 to \u22120.4 mm Hg) in the self-directed group (difference in changes, \u22123.4 mm Hg; 95% CI, \u22125.9 to \u22120.8 mm Hg;\n P<\/jats:italic>\n \u2009=\u2009.009). Compared with the self-directed group, after 3 months the DASH-patterned group changed mean diastolic BP by \u22122.4 mm Hg (95% CI, \u22124.2 to \u22120.5 mm Hg), urine sodium level by \u2212545 mg\/24 h (95% CI, \u22121041 to \u221250 mg\/24 h), and LDL cholesterol by \u22128.0 mg\/dL (95% CI, \u221213.7 to \u22122.3 mg\/dL) (to convert LDL cholesterol to millimoles per liter, multiply by 0.0259). Effects were not maintained 6 months after the intervention was initiated. No effects occurred in BMI or hemoglobin A\n \n 1\n c<\/jats:sc>\n <\/jats:sub>\n level.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and relevance<\/jats:title>\n In this study, a program of home-delivered, DASH-style groceries plus dietitian counseling decreased BP and LDL cholesterol levels beyond comparable monetary compensation. However, effects were not maintained after the intervention ended.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov Identifier:\n NCT05121337<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jama.2025.21112","type":"journal-article","created":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T22:30:26Z","timestamp":1762727426000},"page":"36","source":"Crossref","is-referenced-by-count":22,"title":["DASH-Patterned Groceries and Effects on Blood Pressure"],"prefix":"10.1001","volume":"335","author":[{"given":"Stephen P.","family":"Juraschek","sequence":"first","affiliation":[{"name":"Division of General Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts"},{"name":"Harvard Medical School, Boston, Massachusetts"},{"name":"Department of Nutrition, Harvard T.H. 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