{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T18:11:45Z","timestamp":1773771105700,"version":"3.50.1"},"reference-count":3,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2026,3,17]]},"DOI":"10.1001\/jama.2025.26173","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T16:30:26Z","timestamp":1771259426000},"page":"1008","source":"Crossref","is-referenced-by-count":0,"title":["Personalized Hemodynamic Resuscitation in Early Septic Shock"],"prefix":"10.1001","volume":"335","author":[{"given":"Nicholas A.","family":"Bosch","sequence":"first","affiliation":[{"name":"The Evans Center for Implementation and Improvement Sciences, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10","reference":[{"issue":"22","key":"jle250198r1","doi-asserted-by":"publisher","first-page":"1988","DOI":"10.1001\/jama.2025.20402","article-title":"Personalized hemodynamic resuscitation targeting capillary refill time in early septic shock: the ANDROMEDA-SHOCK-2 randomized clinical trial.","volume":"334","author":"Hernandez","year":"2025","journal-title":"JAMA"},{"key":"jle250198r2","doi-asserted-by":"publisher","first-page":"a1655","DOI":"10.1136\/bmj.a1655","article-title":"Developing and evaluating complex interventions: the new Medical Research Council guidance.","volume":"337","author":"Craig","year":"2008","journal-title":"BMJ"},{"key":"jle250198r3","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/1745-6215-13-95","article-title":"Intervention description is not enough: evidence from an in-depth multiple case study on the untold role and impact of context in randomised controlled trials of seven complex interventions.","volume":"13","author":"Wells","year":"2012","journal-title":"Trials"}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/2845232\/jama_bosch_2026_le_250198_1772738253.37636.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T15:01:02Z","timestamp":1773759662000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2845232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":3,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,3,17]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.2025.26173","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,17]]}}}