{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:31:51Z","timestamp":1793284311531,"version":"4.5.0"},"reference-count":41,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA"],"published-print":{"date-parts":[[2003,1,8]]},"DOI":"10.1001\/jama.289.2.203","type":"journal-article","created":{"date-parts":[[2003,3,18]],"date-time":"2003-03-18T15:05:58Z","timestamp":1047999958000},"page":"203","source":"Crossref","is-referenced-by-count":594,"title":["Effect of Serologic Status and Cesarean Delivery on Transmission Rates of Herpes Simplex Virus From Mother to Infant"],"prefix":"10.1001","volume":"289","author":[{"given":"Zane A.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Wald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Ashley","family":"Morrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacy","family":"Selke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Zeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Corey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"key":"ref-joc20645-1","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1056\/NEJM199710163371601","article-title":"Herpes simplex virus type 2 in the United States, 1976 to 1994.","volume":"337","author":"Fleming","year":"1997","journal-title":"N Engl J Med"},{"key":"ref-joc20645-2","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1093\/aje\/153.9.912","article-title":"Incidence of herpes simplex virus type 2 infection in the United States.","volume":"153","author":"Armstrong","year":"2001","journal-title":"Am J Epidemiol"},{"key":"ref-joc20645-3","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1056\/NEJM199708213370801","article-title":"The acquisition of herpes simplex virus during pregnancy.","volume":"337","author":"Brown","year":"1997","journal-title":"N Engl J Med"},{"key":"ref-joc20645-4","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1542\/peds.66.4.489","article-title":"The natural history of genital herpes simplex virus infection of mother and newborn.","volume":"66","author":"Whitley","year":"1980","journal-title":"Pediatrics"},{"key":"ref-joc20645-5","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/0002-9378(71)90580-1","article-title":"Perinatal risk associated with maternal genital herpes simplex virus infection.","volume":"110","author":"Nahmias","year":"1971","journal-title":"Am J Obstet Gynecol"},{"key":"ref-joc20645-6","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1128\/iai.29.2.532-538.1980","article-title":"Relationship of antibody to outcome in neonatal herpes simplex virus infections.","volume":"29","author":"Yeager","year":"1980","journal-title":"Infect Immun"},{"key":"ref-joc20645-7","first-page":"14","article-title":"Herpes simplex virus and pregnancy.","volume":"100","author":"Forsgren","year":"1996","journal-title":"Scand J Infect Dis Suppl"},{"key":"ref-joc20645-8","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1056\/NEJM199105023241804","article-title":"Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor.","volume":"324","author":"Brown","year":"1991","journal-title":"N Engl J Med"},{"key":"ref-joc20645-9","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1093\/infdis\/157.1.164","article-title":"Type-specific antibodies to herpes simplex virus type 2 (HSV-2) glycoprotein G in pregnant women, infants exposed to maternal HSV-2 infection at delivery, and infants with neonatal herpes.","volume":"157","author":"Sullender","year":"1988","journal-title":"J Infect Dis"},{"key":"ref-joc20645-10","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1056\/NEJM198804073181404","article-title":"Use of routine viral cultures at delivery to identify neonates exposed to herpes simplex virus.","volume":"318","author":"Prober","year":"1988","journal-title":"N Engl J Med"},{"key":"ref-joc20645-11","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/S0020-7292(00)80015-6","article-title":"Management of herpes in pregnancy: clinical management guidelines for obstetrician-gynecologists.","volume":"68","author":"American College of Obstetricians and Gynecologists (ACOG)","year":"2000","journal-title":"Int J Gynaecol Obstet"},{"key":"ref-joc20645-12","first-page":"779","article-title":"Management of genital herpes infection in pregnancy.","volume":"71","author":"Gibbs","year":"1988","journal-title":"Obstet Gynecol"},{"key":"ref-joc20645-13","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1111\/aog.1997.76.issue-4","article-title":"Neonatal herpes in Denmark 1977-1991.","volume":"76","author":"Fonnest","year":"1997","journal-title":"Acta Obstet Gynecol Scand"},{"key":"ref-joc20645-14","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1515\/jpme.1993.21.5.371","article-title":"Neonatal herpes policy in the Netherlands: five years after a consensus conference.","volume":"21","author":"Van Everdingen","year":"1993","journal-title":"J Perinat Med"},{"key":"ref-joc20645-15","first-page":"1832","article-title":"Incidence of herpes neonatorum in the Netherlands.","volume":"144","author":"Gaytant","year":"2000","journal-title":"Ned Tijdschr Geneeskd"},{"key":"ref-joc20645-16","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1001\/jama.1993.03510010083035","article-title":"Cesarean delivery for women presenting with genital herpes lesions: efficacy, risks and costs.","volume":"270","author":"Randolph","year":"1993","journal-title":"JAMA"},{"key":"ref-joc20645-17","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1056\/NEJM199509213331205","article-title":"Virologic characteristics of subclinical and symptomatic genital herpes infections.","volume":"333","author":"Wald","year":"1995","journal-title":"N Engl J Med"},{"key":"ref-joc20645-19","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1128\/JCM.26.9.1772-1774.1988","article-title":"Comparison of diploid fibroblast and rabbit kidney tissue culture and diploid and fibroblast microtiter plate system for the isolation of herpes simplex virus.","volume":"26","author":"Langenberg","year":"1988","journal-title":"J Clin Microbiol"},{"key":"ref-joc20645-20","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1128\/JCM.37.6.1941-1947.1999","article-title":"Development of a high-throughput quantitative assay for detecting HSV DNA in clinical samples.","volume":"37","author":"Ryncarz","year":"1999","journal-title":"J Clin Microbiol"},{"key":"ref-joc20645-21","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1128\/JCM.26.4.662-667.1988","article-title":"Comparison of Western blot (Immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera.","volume":"26","author":"Ashley","year":"1988","journal-title":"J Clin Microbiol"},{"key":"ref-joc20645-22","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1093\/clind\/15.6.1031","article-title":"The management of pregnancies complicated by genital infections with herpes simplex virus.","volume":"15","author":"Prober","year":"1992","journal-title":"Clin Infect Dis"},{"key":"ref-joc20645-23","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1172\/JCI119237","article-title":"Frequent genital herpes simplex virus 2 shedding in immunocompetent women: effect of acyclovir treatment.","volume":"99","author":"Wald","year":"1997","journal-title":"J Clin Invest"},{"key":"ref-joc20645-24","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1097\/00007435-198907000-00007","article-title":"National surveillance for neonatal herpes simplex virus infections.","volume":"16","author":"Stone","year":"1989","journal-title":"Sex Transm Dis"},{"key":"ref-joc20645-25","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1093\/infdis\/158.1.109","article-title":"Changing presentation of herpes simplex virus infection in neonates.","volume":"158","author":"Whitley","year":"1988","journal-title":"J Infect Dis"},{"key":"ref-joc20645-26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0140-6736(88)90997-X","article-title":"Difference in neurologic outcome after antiviral therapy of neonatal central nervous system herpes simplex virus type I versus herpes simplex virus type 2 infection.","volume":"2","author":"Corey","year":"1988","journal-title":"Lancet"},{"key":"ref-joc20645-27","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1016\/S0140-6736(00)04638-9","article-title":"Herpes simplex virus infections.","volume":"357","author":"Whitley","year":"2001","journal-title":"Lancet"},{"key":"ref-joc20645-28","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/j.1365-3016.1996.tb00070.x","article-title":"Neonatal herpes simplex virus infection in the British Isles.","volume":"10","author":"Tookey","year":"1996","journal-title":"Paediatr Perinat Epidemiol"},{"key":"ref-joc20645-29","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1542\/peds.108.2.223","article-title":"Natural history of neonatal herpes simplex virus infections in the acyclovir era.","volume":"108","author":"Kimberlin","year":"2001","journal-title":"Pediatrics"},{"key":"ref-joc20645-30","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1542\/peds.108.2.230","article-title":"Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.","volume":"108","author":"Kimberlin","year":"2001","journal-title":"Pediatrics"},{"key":"ref-joc20645-31","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1136\/sti.77.4.232","article-title":"Sorting out the new HSV type specific antibody tests.","volume":"77","author":"Ashley","year":"2001","journal-title":"Sex Transm Infect"},{"key":"ref-joc20645-32","first-page":"46","article-title":"Should all pregnant women be offered type-specific serological screening for HSV infection?","volume":"9","author":"Kinghorn","year":"2002","journal-title":"Herpes"},{"key":"ref-joc20645-33","doi-asserted-by":"publisher","first-page":"414","DOI":"10.7326\/0003-4819-118-6-199303150-00003","article-title":"Clinical reactivation of herpes simplex virus type 2 infection in seropositive pregnant women with no history of genital herpes.","volume":"118","author":"Frenkel","year":"1993","journal-title":"Ann Intern Med"},{"key":"ref-joc20645-34","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1097\/00007435-200102000-00007","article-title":"Use of a glycoprotein G-based type-specific assay to detect antibodies to herpes simplex virus type 2 among persons attending sexually transmitted disease clinics.","volume":"28","author":"Whittington","year":"2001","journal-title":"Sex Transm Dis"},{"key":"ref-joc20645-35","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/00007435-199907000-00004","article-title":"Correlates of herpes simplex virus seroprevalence among women attending a sexually transmitted disease clinic.","volume":"26","author":"Austin","year":"1999","journal-title":"Sex Transm Dis"},{"key":"ref-joc20645-36","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1093\/clinids\/13.6.1093","article-title":"Strategies for the prevention of neonatal infection with herpes simplex virus: a decision analysis.","volume":"13","author":"Libman","year":"1991","journal-title":"Rev Infect Dis"},{"key":"ref-joc20645-37","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1056\/NEJM199204023261403","article-title":"Identification of women at unsuspected risk of primary infection with herpes simplex virus type 2 during pregnancy.","volume":"326","author":"Kulhanjian","year":"1992","journal-title":"N Engl J Med"},{"key":"ref-joc20645-38","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1002\/(ISSN)1099-1654","article-title":"HSV-2 specific serology should be offered routinely to antenatal patients.","volume":"10","author":"Brown","year":"2000","journal-title":"Rev Med Virol"},{"key":"ref-joc20645-39","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/0029-7844(95)00357-6","article-title":"Acyclovir suppression to prevent cesarean delivery after first-episode genital herpes.","volume":"87","author":"Scott","year":"1996","journal-title":"Obstet Gynecol"},{"key":"ref-joc20645-40","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/bjo.1998.105.issue-3","article-title":"A randomised placebo controlled trial of suppressive acyclovir in late pregnancy in women with recurrent genital herpes infection.","volume":"105","author":"Brocklehurst","year":"1998","journal-title":"Br J Obstet Gynaecol"},{"key":"ref-joc20645-41","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1056\/NEJM200007203430303","article-title":"Rapid detection of group B streptococci in pregnant women at delivery.","volume":"343","author":"Bergeron","year":"2000","journal-title":"N Engl J Med"},{"key":"ref-joc20645-18","first-page":"266","article-title":"Herpes simplex.","volume-title":"1997 Red Book","author":"American Academy of Pediatrics Committee on Infectious Diseases","year":"1977","edition":"24th ed."}],"container-title":["JAMA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/articlepdf\/195747\/joc20645_203_209.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:04:54Z","timestamp":1682467494000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/195747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,8]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,1,8]]}},"URL":"https:\/\/doi.org\/10.1001\/jama.289.2.203","relation":{},"ISSN":["0098-7484"],"issn-type":[{"value":"0098-7484","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1,8]]}}}