{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T19:11:03Z","timestamp":1781291463982,"version":"3.54.1"},"reference-count":45,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Cardiol"],"published-print":{"date-parts":[[2018,8,1]]},"DOI":"10.1001\/jamacardio.2018.1827","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T18:20:43Z","timestamp":1530642043000},"page":"712","source":"Crossref","is-referenced-by-count":18,"title":["Association of <i>APOL1<\/i> With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women"],"prefix":"10.1001","volume":"3","author":[{"given":"Nora","family":"Franceschini","sequence":"first","affiliation":[{"name":"Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey B.","family":"Kopp","sequence":"additional","affiliation":[{"name":"Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Barac","sequence":"additional","affiliation":[{"name":"MedStar Heart and Vascular Institute, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa W.","family":"Martin","sequence":"additional","affiliation":[{"name":"Cardiology Division, George Washington University School of Medicine and Health Sciences, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Statistics and Operations Research, University of North Carolina, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijun","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Statistics and Operations Research, University of North Carolina, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex P.","family":"Reiner","sequence":"additional","affiliation":[{"name":"University of Washington School of Public Health, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Pollak","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Harvard Medical School, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert B.","family":"Wallace","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Iowa College of Public Health, Iowa City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne D.","family":"Rosamond","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl A.","family":"Winkler","sequence":"additional","affiliation":[{"name":"Molecular Genetic Epidemiology Section, Basic Research Laboratory, Basic Science Program, National Cancer Institute Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"10","key":"hoi180029r1","doi-asserted-by":"publisher","first-page":"e146","DOI":"10.1161\/CIR.0000000000000485","article-title":"Heart disease and stroke statistics-2017 update: a report from the American Heart Association.","volume":"135","author":"Benjamin","year":"2017","journal-title":"Circulation"},{"issue":"9","key":"hoi180029r2","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1161\/CIR.0000000000000351","article-title":"Acute myocardial infarction in women: a scientific statement from the American Heart Association.","volume":"133","author":"Mehta","year":"2016","journal-title":"Circulation"},{"issue":"17","key":"hoi180029r3","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1001\/jama.2012.14306","article-title":"Association of race and sex with risk of incident acute coronary heart disease events.","volume":"308","author":"Safford","year":"2012","journal-title":"JAMA"},{"issue":"6","key":"hoi180029r4","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1161\/CIRCULATIONAHA.111.066688","article-title":"Racial and ethnic differences in incident hospitalized heart failure in postmenopausal women: the Women\u2019s Health Initiative.","volume":"126","author":"Eaton","year":"2012","journal-title":"Circulation"},{"issue":"5","key":"hoi180029r5","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1161\/CIRCRESAHA.114.302347","article-title":"Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.","volume":"114","author":"Ito","year":"2014","journal-title":"Circ Res"},{"issue":"2","key":"hoi180029r6","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1161\/ATVBAHA.115.305970","article-title":"APOL1 genotype, kidney and cardiovascular disease, and death in older adults.","volume":"36","author":"Mukamal","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"5993","key":"hoi180029r7","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1126\/science.1193032","article-title":"Association of trypanolytic APOL1 variants with kidney disease in African Americans.","volume":"329","author":"Genovese","year":"2010","journal-title":"Science"},{"issue":"5","key":"hoi180029r8","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1053\/j.ackd.2014.06.005","article-title":"APOL1 kidney risk alleles: population genetics and disease associations.","volume":"21","author":"Limou","year":"2014","journal-title":"Adv Chronic Kidney Dis"},{"issue":"6927","key":"hoi180029r9","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/nature01461","article-title":"Apolipoprotein L-I is the trypanosome lytic factor of human serum.","volume":"422","author":"Vanhamme","year":"2003","journal-title":"Nature"},{"issue":"11","key":"hoi180029r10","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1681\/ASN.2011010069","article-title":"APOL1 localization in normal kidney and nondiabetic kidney disease.","volume":"22","author":"Madhavan","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"hoi180029r11","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1006\/geno.2002.6729","article-title":"The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.","volume":"79","author":"Monajemi","year":"2002","journal-title":"Genomics"},{"issue":"2","key":"hoi180029r12","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1038\/ki.2014.270","article-title":"Innate immunity pathways regulate the nephropathy gene apolipoprotein L1.","volume":"87","author":"Nichols","year":"2015","journal-title":"Kidney Int"},{"issue":"1","key":"hoi180029r13","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1038\/ki.2014.255","article-title":"APOL1 associations with nephropathy, atherosclerosis, and all-cause mortality in African Americans with type 2 diabetes.","volume":"87","author":"Freedman","year":"2015","journal-title":"Kidney Int"},{"issue":"4","key":"hoi180029r14","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/j.ekir.2017.03.008","article-title":"APOL1 renal-risk variants do not associate with incident cardiovascular disease or mortality in the Systolic Blood Pressure Intervention Trial.","volume":"2","author":"Freedman","year":"2017","journal-title":"Kidney Int Rep"},{"issue":"1","key":"hoi180029r15","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1038\/ki.2014.254","article-title":"Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial.","volume":"87","author":"Langefeld","year":"2015","journal-title":"Kidney Int"},{"issue":"12","key":"hoi180029r16","doi-asserted-by":"publisher","first-page":"e007199","DOI":"10.1161\/JAHA.117.007199","article-title":"Association between APOL1 genotypes and risk of cardiovascular disease in MESA (Multi-Ethnic Study of Atherosclerosis).","volume":"6","author":"Chen","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"2","key":"hoi180029r17","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1159\/000453458","article-title":"Apolipoprotein L1 genetic variants are associated with chronic kidney disease but not with cardiovascular disease in a population referred for cardiac catheterization.","volume":"7","author":"Wang","year":"2017","journal-title":"Cardiorenal Med"},{"issue":"5","key":"hoi180029r18","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/S0272-6386(03)00372-X","article-title":"Cardiovascular complications in chronic kidney disease.","volume":"41","author":"Sarnak","year":"2003","journal-title":"Am J Kidney Dis"},{"issue":"13","key":"hoi180029r19","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.","volume":"351","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"issue":"1","key":"hoi180029r20","doi-asserted-by":"publisher","first-page":"A7","DOI":"10.1053\/j.ajkd.2012.11.031","article-title":"US Renal Data System 2012 annual data report.","volume":"61","author":"Collins","year":"2013","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"hoi180029r21","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0197-2456(97)00078-0","article-title":"Design of the Women\u2019s Health Initiative clinical trial and observational study.","volume":"19","author":"The Women\u2019s Health Initiative Study Group","year":"1998","journal-title":"Control Clin Trials"},{"issue":"9","key":"hoi180029r22","doi-asserted-by":"publisher","first-page":"S5","DOI":"10.1016\/S1047-2797(03)00043-7","article-title":"Implementation of the Women\u2019s Health Initiative study design.","volume":"13","author":"Anderson","year":"2003","journal-title":"Ann Epidemiol"},{"issue":"7","key":"hoi180029r23","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1056\/NEJMoa055218","article-title":"Calcium plus vitamin D supplementation and the risk of fractures.","volume":"354","author":"Jackson","year":"2006","journal-title":"N Engl J Med"},{"issue":"1","key":"hoi180029r24","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1373\/clinchem.2005.0525144","article-title":"Recommendations for improving serum creatinine measurement: a report from the Laboratory Working Group of the National Kidney Disease Education Program.","volume":"52","author":"Myers","year":"2006","journal-title":"Clin Chem"},{"issue":"9","key":"hoi180029r25","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate.","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"issue":"21","key":"hoi180029r26","doi-asserted-by":"publisher","first-page":"2744","DOI":"10.1093\/bioinformatics\/btt477","article-title":"Imputation of coding variants in African Americans: better performance using data from the exome sequencing project.","volume":"29","author":"Duan","year":"2013","journal-title":"Bioinformatics"},{"issue":"8","key":"hoi180029r27","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1038\/ng1847","article-title":"Principal components analysis corrects for stratification in genome-wide association studies.","volume":"38","author":"Price","year":"2006","journal-title":"Nat Genet"},{"issue":"9","key":"hoi180029r28","doi-asserted-by":"publisher","first-page":"S122","DOI":"10.1016\/S1047-2797(03)00048-6","article-title":"Outcomes ascertainment and adjudication methods in the Women\u2019s Health Initiative.","volume":"13","author":"Curb","year":"2003","journal-title":"Ann Epidemiol"},{"issue":"2","key":"hoi180029r29","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1161\/CIRCHEARTFAILURE.111.963199","article-title":"Classification of heart failure in the atherosclerosis risk in communities (ARIC) study: a comparison of diagnostic criteria.","volume":"5","author":"Rosamond","year":"2012","journal-title":"Circ Heart Fail"},{"issue":"10","key":"hoi180029r30","doi-asserted-by":"publisher","first-page":"e002883","DOI":"10.1161\/CIRCHEARTFAILURE.115.002883","article-title":"Risk factors for incident hospitalized heart failure with preserved versus reduced ejection fraction in a multiracial cohort of postmenopausal women.","volume":"9","author":"Eaton","year":"2016","journal-title":"Circ Heart Fail"},{"issue":"5","key":"hoi180029r31","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1001\/jama.2010.39","article-title":"Relation between kidney function, proteinuria, and adverse outcomes.","volume":"303","author":"Hemmelgarn","year":"2010","journal-title":"JAMA"},{"issue":"6","key":"hoi180029r32","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1016\/j.jacc.2017.04.025","article-title":"2017 ACC\/AHA\/HFSA focused update of the 2013 ACCF\/AHA guideline for the management of heart failure: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America.","volume":"70","author":"Yancy","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"20","key":"hoi180029r33","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1001\/jama.1996.03530440037034","article-title":"The progression from hypertension to congestive heart failure.","volume":"275","author":"Levy","year":"1996","journal-title":"JAMA"},{"issue":"1","key":"hoi180029r34","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/eurjhf\/hfq121","article-title":"Epidemiology and clinical course of heart failure with preserved ejection fraction.","volume":"13","author":"Lam","year":"2011","journal-title":"Eur J Heart Fail"},{"issue":"19","key":"hoi180029r35","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1093\/eurheartj\/eht066","article-title":"Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND.","volume":"34","author":"Brouwers","year":"2013","journal-title":"Eur Heart J"},{"issue":"4","key":"hoi180029r36","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.jchf.2015.10.007","article-title":"Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction.","volume":"4","author":"Franssen","year":"2016","journal-title":"JACC Heart Fail"},{"issue":"19","key":"hoi180029r37","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1016\/j.jacc.2009.12.045","article-title":"Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study.","volume":"55","author":"Kalogeropoulos","year":"2010","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"hoi180029r38","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1681\/ASN.2012121180","article-title":"Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy.","volume":"24","author":"Larsen","year":"2013","journal-title":"J Am Soc Nephrol"},{"issue":"2","key":"hoi180029r39","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1038\/tpj.2016.4","article-title":"A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials.","volume":"17","author":"de Denus","year":"2017","journal-title":"Pharmacogenomics J"},{"issue":"510","key":"hoi180029r40","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1080\/01621459.2015.1008099","article-title":"Analysis of sequence data under multivariate trait-dependent sampling.","volume":"110","author":"Tao","year":"2015","journal-title":"J Am Stat Assoc"},{"issue":"4","key":"hoi180029r41","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1016\/j.kint.2017.03.028","article-title":"APOL1 genetic variants are not associated with longitudinal blood pressure in young black adults.","volume":"92","author":"Chen","year":"2017","journal-title":"Kidney Int"},{"issue":"3","key":"hoi180029r42","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1016\/j.kint.2017.08.019","article-title":"APOL1 nephropathy risk variants do not associate with subclinical atherosclerosis or left ventricular mass in middle-aged black adults.","volume":"93","author":"Guti\u00e9rrez","year":"2018","journal-title":"Kidney Int"},{"issue":"9","key":"hoi180029r43","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1681\/ASN.2013010113","article-title":"APOL1 variants associate with increased risk of CKD among African Americans.","volume":"24","author":"Foster","year":"2013","journal-title":"J Am Soc Nephrol"},{"issue":"2","key":"hoi180029r44","doi-asserted-by":"publisher","first-page":"241","DOI":"10.2215\/CJN.02860314","article-title":"Adiposity patterns and the risk for ESRD in postmenopausal women.","volume":"10","author":"Franceschini","year":"2015","journal-title":"Clin J Am Soc Nephrol"},{"issue":"9","key":"hoi180029r45","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1161\/ATVBAHA.117.309384","article-title":"APOL1 risk variants and cardiovascular disease: results from the AASK (African American Study of Kidney Disease and Hypertension).","volume":"37","author":"Chen","year":"2017","journal-title":"Arterioscler Thromb Vasc Biol"}],"container-title":["JAMA Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamacardiology\/fullarticle\/2686710","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,15]],"date-time":"2018-08-15T16:31:00Z","timestamp":1534350660000},"score":1,"resource":{"primary":{"URL":"http:\/\/cardiology.jamanetwork.com\/article.aspx?doi=10.1001\/jamacardio.2018.1827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,1]]},"references-count":45,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamacardio.2018.1827","relation":{},"ISSN":["2380-6583"],"issn-type":[{"value":"2380-6583","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,1]]}}}