{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:25:27Z","timestamp":1790695527936,"version":"4.1.0"},"reference-count":19,"publisher":"American Medical Association (AMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Cardiol"],"published-print":{"date-parts":[[2018,9,1]]},"DOI":"10.1001\/jamacardio.2018.2251","type":"journal-article","created":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T16:38:16Z","timestamp":1533141496000},"page":"877","source":"Crossref","is-referenced-by-count":38,"title":["Association of Oral Contraceptives With Drug-Induced QT Interval Prolongation in Healthy Nonmenopausal Women"],"prefix":"10.1001","volume":"3","author":[{"given":"Joe-Elie","family":"Salem","sequence":"first","affiliation":[{"name":"Centres d\u2019Investigation Clinique Paris-Est, Assistance Publique des H\u00f4pitaux de Paris, Department of Pharmacology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"},{"name":"Sorbonne-Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Research Unit on Cardiovascular, Metabolic And Nutrition Diseases (UMRS-1166), Institute of Cardiometabolism and Nutrition, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Dureau","sequence":"additional","affiliation":[{"name":"Centres d\u2019Investigation Clinique Paris-Est, Assistance Publique des H\u00f4pitaux de Paris, Department of Pharmacology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Bachelot","sequence":"additional","affiliation":[{"name":"Assistance Publique des H\u00f4pitaux de Paris, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Institut Endocrinologie, des Maladies M\u00e9taboliques et de M\u00e9decine Interne, Department of Endocrinology and Reproductive Medicine, Centre de R\u00e9f\u00e9rence des Maladies Endocriniennes Rares de la Croissance et Centre des Pathologies Gyn\u00e9cologiques Rares, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Germain","sequence":"additional","affiliation":[{"name":"Sorbonne-Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Research Unit on Cardiovascular, Metabolic And Nutrition Diseases (UMRS-1166), Institute of Cardiometabolism and Nutrition, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Voiriot","sequence":"additional","affiliation":[{"name":"Cardiabase, Banook Group, Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Lebourgeois","sequence":"additional","affiliation":[{"name":"Centres d\u2019Investigation Clinique Paris-Est, Assistance Publique des H\u00f4pitaux de Paris, Department of Pharmacology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David-Alexandre","family":"Tr\u00e9gou\u00ebt","sequence":"additional","affiliation":[{"name":"Sorbonne-Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Research Unit on Cardiovascular, Metabolic And Nutrition Diseases (UMRS-1166), Institute of Cardiometabolism and Nutrition, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-S\u00e9bastien","family":"Hulot","sequence":"additional","affiliation":[{"name":"Centres d\u2019Investigation Clinique Paris-Est, Assistance Publique des H\u00f4pitaux de Paris, Department of Pharmacology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"},{"name":"Sorbonne-Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Research Unit on Cardiovascular, Metabolic And Nutrition Diseases (UMRS-1166), Institute of Cardiometabolism and Nutrition, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Funck-Brentano","sequence":"additional","affiliation":[{"name":"Centres d\u2019Investigation Clinique Paris-Est, Assistance Publique des H\u00f4pitaux de Paris, Department of Pharmacology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"},{"name":"Sorbonne-Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Research Unit on Cardiovascular, Metabolic And Nutrition Diseases (UMRS-1166), Institute of Cardiometabolism and Nutrition, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"key":"hbr180012r1","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.pharmthera.2016.07.005","article-title":"Influence of steroid hormones on ventricular repolarization.","volume":"167","author":"Salem","year":"2016","journal-title":"Pharmacol Ther"},{"issue":"7","key":"hbr180012r2","doi-asserted-by":"publisher","first-page":"2776","DOI":"10.1210\/jc.2016-1877","article-title":"Complex influence of gonadotropins and sex steroid hormones on QT interval duration.","volume":"101","author":"Abehsira","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"hbr180012r3","article-title":"Hypogonadism as a reversible cause of torsades de pointes in men","volume":"138","author":"Salem","year":"2018","journal-title":"Cir Cir"},{"issue":"4","key":"hbr180012r4","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1111\/anec.12050","article-title":"Oral contraceptive use and the ECG: evidence of an adverse QT effect on corrected QT interval.","volume":"18","author":"Sedlak","year":"2013","journal-title":"Ann Noninvasive Electrocardiol"},{"issue":"10","key":"hbr180012r5","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1056\/NEJMra032426","article-title":"Drug-induced prolongation of the QT interval.","volume":"350","author":"Roden","year":"2004","journal-title":"N Engl J Med"},{"issue":"7","key":"hbr180012r6","first-page":"473","article-title":"Drug-induced QT prolongation and torsades de pointes.","volume":"42","author":"Li","year":"2017","journal-title":"P T"},{"issue":"8","key":"hbr180012r7","doi-asserted-by":"publisher","first-page":"e0181875","DOI":"10.1371\/journal.pone.0181875","article-title":"Genome wide analysis of sotalol-induced Ikr inhibition during ventricular Repolarization, \u201cGENEREPOL study\u201d: lack of common variants with large effect sizes.","volume":"12","author":"Salem","year":"2017","journal-title":"PLoS One"},{"issue":"7","key":"hbr180012r8","doi-asserted-by":"publisher","first-page":"599","DOI":"10.2165\/00002018-200932070-00006","article-title":"Identifying drug-induced repolarization abnormalities from distinct ECG patterns in congenital long QT syndrome: a study of sotalol effects on T-wave morphology.","volume":"32","author":"Graff","year":"2009","journal-title":"Drug Saf"},{"issue":"202","key":"hbr180012r9","first-page":"61134","article-title":"International conference on harmonisation; guidance on E14 Clinical Evaluation of QT\/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs; availability. notice.","volume":"70","author":"US Food and Drug Administration","year":"2005","journal-title":"Fed Regist"},{"issue":"8-9","key":"hbr180012r10","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.acvd.2016.12.011","article-title":"Fast, accurate and easy-to-teach QT interval assessment: The triplicate concatenation method.","volume":"110","author":"Saqu\u00e9","year":"2017","journal-title":"Arch Cardiovasc Dis"},{"key":"hbr180012r12","first-page":"heartjnl-2017-312934","article-title":"Increased long QT and torsade de pointes reporting on tamoxifen compared with aromatase inhibitors.","volume":"pii","author":"Grouthier","year":"2018","journal-title":"Heart"},{"issue":"6","key":"hbr180012r13","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1093\/eurheartj\/ehi092","article-title":"Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death.","volume":"26","author":"De Bruin","year":"2005","journal-title":"Eur Heart J"},{"issue":"2","key":"hbr180012r14","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.ccep.2016.02.007","article-title":"Sotalol.","volume":"8","author":"Kpaeyeh","year":"2016","journal-title":"Card Electrophysiol Clin"},{"key":"hbr180012r15","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1093\/eurheartj\/14.suppl_H.30","article-title":"Pharmacokinetic and pharmacodynamic profiles of d-sotalol and d,l-sotalol.","volume":"14","author":"Funck-Brentano","year":"1993","journal-title":"Eur Heart J"},{"issue":"1-2","key":"hbr180012r16","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.maturitas.2008.11.011","article-title":"Pharmacological profile of progestins.","volume":"61","author":"Sitruk-Ware","year":"2008","journal-title":"Maturitas"},{"issue":"10","key":"hbr180012r17","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1001\/jama.285.10.1322","article-title":"Drug-induced QT prolongation in women during the menstrual cycle.","volume":"285","author":"Rodriguez","year":"2001","journal-title":"JAMA"},{"issue":"5","key":"hbr180012r19","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.contraception.2016.01.010","article-title":"Trends in direct-to-consumer advertising of prescription contraceptives.","volume":"93","author":"Wu","year":"2016","journal-title":"Contraception"},{"key":"hbr180012r11","unstructured":"European Medicines Agency. Eudravigilance: European database of suspected adverse drug reaction reports: online access to suspected side-effect reports. http:\/\/www.adrreports.eu\/en\/index.html. Accessed June 20, 2018."},{"key":"hbr180012r18","unstructured":"B\u00f6hmR. OpenVigil Cave-at document; Version 2.0.2. http:\/\/openvigil.sourceforge.net\/doc\/openvigil-cave-at-v2.html. Published September 14, 2015. Accessed June 20, 2018."}],"container-title":["JAMA Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamacardiology\/fullarticle\/2695044","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T12:10:16Z","timestamp":1537359016000},"score":1,"resource":{"primary":{"URL":"http:\/\/cardiology.jamanetwork.com\/article.aspx?doi=10.1001\/jamacardio.2018.2251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,1]]},"references-count":19,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamacardio.2018.2251","relation":{},"ISSN":["2380-6583"],"issn-type":[{"value":"2380-6583","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9,1]]}}}