{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T22:15:38Z","timestamp":1793398538820,"version":"4.5.0"},"reference-count":35,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Cardiol"],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"Importance<\/jats:title>The frequency and clinical importance of structural valve deterioration (SVD) in patients undergoing self-expanding transcatheter aortic valve implantation (TAVI) or surgery is poorly understood.<\/jats:p><\/jats:sec>Objective<\/jats:title>To evaluate the 5-year incidence, clinical outcomes, and predictors of hemodynamic SVD in patients undergoing self-expanding TAVI or surgery.<\/jats:p><\/jats:sec>Design, Setting, and Participants<\/jats:title>This post hoc analysis pooled data from the CoreValve US High Risk Pivotal (n\u2009=\u2009615) and SURTAVI (n\u2009=\u20091484) randomized clinical trials (RCTs); it was supplemented by the CoreValve Extreme Risk Pivotal trial (n\u2009=\u2009485) and CoreValve Continued Access Study (n\u2009=\u20092178). Patients with severe aortic valve stenosis deemed to be at intermediate or increased risk of 30-day surgical mortality were included. Data were collected from December 2010 to June 2016, and data were analyzed from December 2021 to October 2022.<\/jats:p><\/jats:sec>Interventions<\/jats:title>Patients were randomized to self-expanding TAVI or surgery in the RCTs or underwent self-expanding TAVI for clinical indications in the nonrandomized studies.<\/jats:p><\/jats:sec>Main Outcomes and Measures<\/jats:title>The primary end point was the incidence of SVD through 5 years (from the RCTs). Factors associated with SVD and its association with clinical outcomes were evaluated for the pooled RCT and non-RCT population. SVD was defined as (1) an increase in mean gradient of 10 mm Hg or greater from discharge or at 30 days to last echocardiography with a final mean gradient of 20 mm Hg or greater or (2) new-onset moderate or severe intraprosthetic aortic regurgitation or an increase of 1 grade or more.<\/jats:p><\/jats:sec>Results<\/jats:title>Of 4762 included patients, 2605 (54.7%) were male, and the mean (SD) age was 82.1 (7.4) years. A total of 2099 RCT patients, including 1128 who received TAVI and 971 who received surgery, and 2663 non-RCT patients who received TAVI were included. The cumulative incidence of SVD treating death as a competing risk was lower in patients undergoing TAVI than surgery (TAVI, 2.20%; surgery, 4.38%; hazard ratio [HR], 0.46; 95% CI, 0.27-0.78; P<\/jats:italic>\u2009=\u2009.004). This lower risk was most pronounced in patients with smaller annuli (23 mm diameter or smaller; TAVI, 1.32%; surgery, 5.84%; HR, 0.21; 95% CI, 0.06-0.73; P<\/jats:italic>\u2009=\u2009.02). SVD was associated with increased 5-year all-cause mortality (HR, 2.03; 95% CI, 1.46-2.82; P<\/jats:italic>\u2009&amp;lt;\u2009.001), cardiovascular mortality (HR, 1.86; 95% CI, 1.20-2.90; P<\/jats:italic>\u2009=\u2009.006), and valve disease or worsening heart failure hospitalizations (HR, 2.17; 95% CI, 1.23-3.84; P<\/jats:italic>\u2009=\u2009.008). Predictors of SVD were developed from multivariate analysis.<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>This study found a lower rate of SVD in patients undergoing self-expanding TAVI vs surgery at 5 years. Doppler echocardiography was a valuable tool to detect SVD, which was associated with worse clinical outcomes.<\/jats:p><\/jats:sec>Trial Registration<\/jats:title>ClinicalTrials.gov Identifiers: NCT01240902<\/jats:ext-link>, NCT01586910<\/jats:ext-link>, and NCT01531374<\/jats:ext-link><\/jats:p><\/jats:sec>","DOI":"10.1001\/jamacardio.2022.4627","type":"journal-article","created":{"date-parts":[[2022,12,14]],"date-time":"2022-12-14T16:00:42Z","timestamp":1671033642000},"page":"111","source":"Crossref","is-referenced-by-count":121,"title":["Structural Valve Deterioration After Self-Expanding Transcatheter or Surgical Aortic Valve Implantation in Patients at Intermediate or High Risk"],"prefix":"10.1001","volume":"8","author":[{"given":"Daniel","family":"O\u2019Hair","sequence":"first","affiliation":[{"name":"Cardiovascular Service Line, Boulder Community Health, Boulder, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J.","family":"Yakubov","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Ohio Health Riverside Methodist Hospital, Columbus"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendra J.","family":"Grubb","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae K.","family":"Oh","sequence":"additional","affiliation":[{"name":"Echocardiography Core Laboratory, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saki","family":"Ito","sequence":"additional","affiliation":[{"name":"Echocardiography Core Laboratory, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Michael","family":"Deeb","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, University of Michigan Hospitals, Ann Arbor"},{"name":"Department of Cardiac Surgery, University of Michigan Hospitals, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas M.","family":"Van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mount Sinai Health System, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanvir","family":"Bajwa","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Aurora St. Luke\u2019s Medical Center, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal S.","family":"Kleiman","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"},{"name":"Department of Cardiothoracic Surgery, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Chetcuti","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, University of Michigan Hospitals, Ann Arbor"},{"name":"Department of Cardiac Surgery, University of Michigan Hospitals, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"S\u00f8ndergaard","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemal","family":"Gada","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania"},{"name":"Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mubashir","family":"Mumtaz","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania"},{"name":"Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center Pinnacle Health, Harrisburg, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Heiser","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Spectrum Health, Grand Rapids, Michigan"},{"name":"Department of Cardiothoracic Surgery, Spectrum Health, Grand Rapids, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William M.","family":"Merhi","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, Spectrum Health, Grand Rapids, Michigan"},{"name":"Department of Cardiothoracic Surgery, Spectrum Health, Grand Rapids, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Petrossian","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Saint Francis Hospital, Roslyn, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Newell","family":"Robinson","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Saint Francis Hospital, Roslyn, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert H. L.","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mount Sinai Health System, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Rovin","sequence":"additional","affiliation":[{"name":"Center for Advanced Valve and Structural Heart Care, Morton Plant Hospital, Clearwater, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen H.","family":"Little","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"},{"name":"Department of Cardiothoracic Surgery, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renuka","family":"Jain","sequence":"additional","affiliation":[{"name":"Aurora Cardiovascular Services, Aurora-St. Luke\u2019s Medical Center, Milwaukee, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Verdoliva","sequence":"additional","affiliation":[{"name":"Structural Heart and Aortic, Medtronic, Minneapolis, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Hanson","sequence":"additional","affiliation":[{"name":"Structural Heart and Aortic, Medtronic, Minneapolis, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuzhen","family":"Li","sequence":"additional","affiliation":[{"name":"Structural Heart and Aortic, Medtronic, Minneapolis, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey J.","family":"Popma","sequence":"additional","affiliation":[{"name":"Structural Heart and Aortic, Medtronic, Minneapolis, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Reardon","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"},{"name":"Department of Cardiothoracic Surgery, Houston Methodist DeBakey Heart and Vascular Center, Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"17","key":"hoi220078r1","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","article-title":"Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.","volume":"363","author":"Leon","year":"2010","journal-title":"N Engl J Med"},{"issue":"19","key":"hoi220078r2","doi-asserted-by":"publisher","first-page":"1972","DOI":"10.1016\/j.jacc.2014.02.556","article-title":"Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery.","volume":"63","author":"Popma","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"23","key":"hoi220078r3","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1056\/NEJMoa1103510","article-title":"Transcatheter versus surgical aortic-valve replacement in high-risk patients.","volume":"364","author":"Smith","year":"2011","journal-title":"N Engl J Med"},{"issue":"19","key":"hoi220078r4","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1056\/NEJMoa1400590","article-title":"Transcatheter aortic-valve replacement with a self-expanding prosthesis.","volume":"370","author":"Adams","year":"2014","journal-title":"N Engl J Med"},{"issue":"17","key":"hoi220078r5","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1056\/NEJMoa1514616","article-title":"Transcatheter or surgical aortic-valve replacement in intermediate-risk patients.","volume":"374","author":"Leon","year":"2016","journal-title":"N Engl J Med"},{"issue":"14","key":"hoi220078r6","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.1056\/NEJMoa1700456","article-title":"Surgical or transcatheter aortic-valve replacement in intermediate-risk patients.","volume":"376","author":"Reardon","year":"2017","journal-title":"N Engl J Med"},{"issue":"18","key":"hoi220078r7","doi-asserted-by":"publisher","first-page":"1695","DOI":"10.1056\/NEJMoa1814052","article-title":"Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients.","volume":"380","author":"Mack","year":"2019","journal-title":"N Engl J Med"},{"issue":"18","key":"hoi220078r8","doi-asserted-by":"publisher","first-page":"1706","DOI":"10.1056\/NEJMoa1816885","article-title":"Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients.","volume":"380","author":"Popma","year":"2019","journal-title":"N Engl J Med"},{"issue":"4","key":"hoi220078r9","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.1016\/j.jacc.2020.11.018","article-title":"2020 ACC\/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines.","volume":"77","author":"Otto","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"hoi220078r10","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1093\/eurheartj\/ehab395","article-title":"2021 ESC\/EACTS Guidelines for the management of valvular heart disease.","volume":"43","author":"Vahanian","year":"2022","journal-title":"Eur Heart J"},{"issue":"11","key":"hoi220078r11","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1016\/j.jcin.2021.03.058","article-title":"Transcatheter versus surgical aortic valve replacement in young, low-risk patients with severe aortic stenosis.","volume":"14","author":"Yerasi","year":"2021","journal-title":"JACC Cardiovasc Interv"},{"issue":"4","key":"hoi220078r12","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1016\/j.athoracsur.2014.10.070","article-title":"Long-term durability of bioprosthetic aortic valves: implications from 12,569 implants.","volume":"99","author":"Johnston","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"45","key":"hoi220078r13","doi-asserted-by":"publisher","first-page":"3382","DOI":"10.1093\/eurheartj\/ehx303","article-title":"Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS).","volume":"38","author":"Capodanno","year":"2017","journal-title":"Eur Heart J"},{"issue":"21","key":"hoi220078r14","doi-asserted-by":"publisher","first-page":"2717","DOI":"10.1016\/j.jacc.2021.02.038","article-title":"Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research.","volume":"77","author":"G\u00e9n\u00e9reux","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"30","key":"hoi220078r15","doi-asserted-by":"publisher","first-page":"2912","DOI":"10.1093\/eurheartj\/ehab375","article-title":"Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement.","volume":"42","author":"J\u00f8rgensen","year":"2021","journal-title":"Eur Heart J"},{"key":"hoi220078r16","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.amjcard.2021.07.046","article-title":"Meta-analysis comparing valve durability among different transcatheter and surgical aortic valve bioprosthesis.","volume":"158","author":"Ueyama","year":"2021","journal-title":"Am J Cardiol"},{"issue":"6","key":"hoi220078r17","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.120.010258","article-title":"Five-year clinical and quality of life outcomes from the CoreValve US Pivotal Extreme Risk trial.","volume":"14","author":"Arnold","year":"2021","journal-title":"Circ Cardiovasc Interv"},{"issue":"22","key":"hoi220078r18","doi-asserted-by":"publisher","first-page":"2687","DOI":"10.1016\/j.jacc.2018.08.2146","article-title":"5-Year outcomes of self-expanding transcatheter versus surgical aortic valve replacement in high-risk patients.","volume":"72","author":"Gleason","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"hoi220078r19","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1001\/jamacardio.2022.2695","article-title":"Self-expanding transcatheter vs surgical aortic valve replacement in intermediate-risk patients: 5-year outcomes of the SURTAVI randomized clinical trial.","volume":"7","author":"Van Mieghem","year":"2022","journal-title":"JAMA Cardiol"},{"key":"hoi220078r20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ahj.2017.09.005","article-title":"Valve hemodynamic deterioration and cardiovascular outcomes in TAVR: a report from the STS\/ACC TVT registry.","volume":"195","author":"Vemulapalli","year":"2018","journal-title":"Am Heart J"},{"issue":"18","key":"hoi220078r21","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1016\/S0735-1097(21)02263-4","article-title":"Relationship of hemodynamic valve deterioration and late clinical outcomes after TAVR with a self-expanding bioprosthesis and surgery.","volume":"77","author":"O\u2019Hair","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"11","key":"hoi220078r22","doi-asserted-by":"publisher","first-page":"2217","DOI":"10.1080\/00949655.2015.1106543","article-title":"Multiple imputation for competing risks regression with interval-censored data.","volume":"86","author":"Delord","year":"2016","journal-title":"J Stat Comput Simul"},{"issue":"22","key":"hoi220078r23","doi-asserted-by":"publisher","first-page":"2147","DOI":"10.1016\/j.jacc.2021.09.861","article-title":"Life expectancy after surgical aortic valve replacement.","volume":"78","author":"Martinsson","year":"2021","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"hoi220078r24","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1161\/CIRCULATIONAHA.117.030729","article-title":"Standardized definition of structural valve degeneration for surgical and transcatheter bioprosthetic aortic valves.","volume":"137","author":"Dvir","year":"2018","journal-title":"Circulation"},{"issue":"9","key":"hoi220078r25","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1016\/j.echo.2009.07.013","article-title":"Recommendations for evaluation of prosthetic valves with echocardiography and doppler ultrasound: a report From the American Society of Echocardiography\u2019s Guidelines and Standards Committee and the Task Force on Prosthetic Valves, developed in conjunction with the American College of Cardiology Cardiovascular Imaging Committee, Cardiac Imaging Committee of the American Heart Association, the European Association of Echocardiography, a registered branch of the European Society of Cardiology, the Japanese Society of Echocardiography and the Canadian Society of Echocardiography, endorsed by the American College of Cardiology Foundation, American Heart Association, European Association of Echocardiography, a registered branch of the European Society of Cardiology, the Japanese Society of Echocardiography, and Canadian Society of Echocardiography.","volume":"22","author":"Zoghbi","year":"2009","journal-title":"J Am Soc Echocardiogr"},{"issue":"7","key":"hoi220078r26","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.echo.2022.01.019","article-title":"Performance of echocardiographic algorithms for assessment of high aortic bioprosthetic valve gradients.","volume":"35","author":"Roslan","year":"2022","journal-title":"J Am Soc Echocardiogr"},{"issue":"3","key":"hoi220078r27","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1177\/021849230601400306","article-title":"15-Year comparison of supra-annular porcine and PERIMOUNT aortic bioprostheses.","volume":"14","author":"Jamieson","year":"2006","journal-title":"Asian Cardiovasc Thorac Ann"},{"issue":"1","key":"hoi220078r28","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1001\/jamainternmed.2016.6936","article-title":"National registry data and record linkage to inform postmarket surveillance of prosthetic aortic valve models over 15 years.","volume":"177","author":"Hickey","year":"2017","journal-title":"JAMA Intern Med"},{"issue":"4","key":"hoi220078r29","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1016\/j.jtcvs.2017.05.044","article-title":"Early Trifecta valve failure: report of a cluster of cases from a tertiary care referral center.","volume":"154","author":"Kalra","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"3","key":"hoi220078r30","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1016\/j.jtcvs.2016.09.089","article-title":"Midterm, multicenter clinical and hemodynamic results for the Trifecta aortic pericardial valve.","volume":"153","author":"Goldman","year":"2017","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"2","key":"hoi220078r31","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.jtcvs.2019.05.081","article-title":"Surgical valve selection in the era of transcatheter aortic valve replacement in the Society of Thoracic Surgeons Database.","volume":"159","author":"Tam","year":"2020","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"16","key":"hoi220078r32","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1016\/j.jacc.2020.08.049","article-title":"Structural deterioration of transcatheter versus surgical aortic valve bioprostheses in the PARTNER-2 Trial.","volume":"76","author":"Pibarot","year":"2020","journal-title":"J Am Coll Cardiol"},{"issue":"23","key":"hoi220078r33","doi-asserted-by":"publisher","first-page":"2597","DOI":"10.1161\/CIRCULATIONAHA.118.036866","article-title":"Five-year clinical outcome and valve durability after transcatheter aortic valve replacement in high-risk patients.","volume":"138","author":"Didier","year":"2018","journal-title":"Circulation"},{"issue":"9","key":"hoi220078r34","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1016\/j.jcin.2019.12.026","article-title":"5-Year outcomes after TAVR with balloon-expandable versus self-expanding valves: results from the CHOICE randomized clinical trial.","volume":"13","author":"Abdel-Wahab","year":"2020","journal-title":"JACC Cardiovasc Interv"},{"key":"hoi220078r35","unstructured":"Small Annuli Randomized To Evolut or SAPIEN Trial (SMART). ClinicalTrials.gov identifier: NCT04722250. Updated September 15, 2022. Accessed May 4, 2022. https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04722250"}],"container-title":["JAMA Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamacardiology\/articlepdf\/2799709\/jamacardiology_ohair_2022_oi_220078_1675366806.26293.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T16:07:26Z","timestamp":1675872446000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamacardiology\/fullarticle\/2799709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,1]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamacardio.2022.4627","relation":{},"ISSN":["2380-6583"],"issn-type":[{"value":"2380-6583","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2,1]]}}}