{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:26:49Z","timestamp":1793824009372,"version":"4.6.1"},"reference-count":13,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Cardiol"],"published-print":{"date-parts":[[2025,11,1]]},"abstract":"<jats:sec id=\"ab-hbr250014-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Transcatheter aortic valve replacement (TAVR) reintervention is performed by either redo TAVR or TAVR explant. There is insufficient data on contemporary TAVR reintervention procedural incidence and volume.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate contemporary procedural volumes of redo TAVR and TAVR explant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This retrospective analysis of redo TAVR and TAVR explant annual incidence and procedural volume was performed from January 2012 to June 2024. For comprehensive assessment of aortic valve replacement, analysis of SAVR reintervention annual incidence and procedural volume was also performed. Data were obtained through the US Centers for Medicare &amp;amp;amp; Medicaid Services Virtual Research Data Center. Patients with prior TAVR or SAVR who underwent subsequent TAVR or SAVR were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-7\">\n                    <jats:title>Exposures<\/jats:title>\n                    <jats:p>Patients who underwent a TAVR after TAVR defined the redo TAVR group, while patients who underwent SAVR after TAVR defined the TAVR explant group. Patients who underwent a TAVR after SAVR defined the valve-in-valve (ViV) TAVR group, while patients who underwent SAVR after SAVR defined the redo SAVR group. Analysis of annual incidences and procedural volumes of all groups at different time intervals was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-8\">\n                    <jats:title>Main Outcomes and Measures<\/jats:title>\n                    <jats:p>The primary outcome was annual incidence and procedural volume of both redo TAVR and TAVR explant. The secondary outcome was annual incidence and procedural volume of both ViV TAVR and redo SAVR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-9\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 410\u202f720 total TAVRs from 2012 to 2024, 2374 redo TAVRs and 1346 TAVR explants were identified. Of 299\u202f780 total SAVRs from 2012 to 2024, 5044 ViV-TAVRs and 4202 redo SAVRs were identified. Since 2020, there have been 1518 redo TAVRs and 1007 TAVR explants. The annual incidence of TAVR reintervention has changed from 0.17% in 2019 to 0.28% in 2023. Although the most common time interval for redo TAVR after index TAVR was within 3 months (410 of 2374 [17.3%]) and for TAVR explant after index TAVR was 1 to 2 years (259 of 1346 [19.2%]), redo TAVR was the predominant procedure beyond 5 years from the index TAVR (725 of 819 [88.5%]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-hbr250014-10\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>In this study, annual volumes of both redo TAVR and TAVR explant continued to increase, particularly in recent years. Redo TAVR is frequently performed over 5 years from the index TAVR. Future analysis to determine the appropriate TAVR reintervention strategy for individual patients is needed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamacardio.2025.3224","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T15:31:12Z","timestamp":1758727872000},"page":"1201","source":"Crossref","is-referenced-by-count":14,"title":["Contemporary Incidence and Procedural Volume of Transcatheter Aortic Valve Reintervention"],"prefix":"10.1001","volume":"10","author":[{"given":"Maxwell C.","family":"Braasch","sequence":"first","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Washington University in St Louis, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia R.","family":"Pyeatte","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Washington University in St Louis, St Louis, 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Washington University in St Louis, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Zajarias","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine, Washington University in St Louis, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Kouchoukos","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Washington University in St Louis, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery, Department of Surgery, Washington University in St Louis, St Louis, 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