{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:54:11Z","timestamp":1790639651149,"version":"4.1.0"},"reference-count":6,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2019,2,1]]},"DOI":"10.1001\/jamadermatol.2018.4653","type":"journal-article","created":{"date-parts":[[2018,12,19]],"date-time":"2018-12-19T19:07:32Z","timestamp":1545246452000},"page":"256","source":"Crossref","is-referenced-by-count":144,"title":["Genotype-Guided Medical Treatment of an Arteriovenous Malformation in a Child"],"prefix":"10.1001","volume":"155","author":[{"given":"Ramrada","family":"Lekwuttikarn","sequence":"first","affiliation":[{"name":"Division of Pediatric Dermatology, Department of Dermatology, Stanford University School of Medicine, Stanford, California"},{"name":"Section of Dermatology, Division of Ambulatory and Adolescent Medicine, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young H.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yale School of Medicine, New Haven, Connecticut"},{"name":"Department of Pathology, Yale School of Medicine, New Haven, Connecticut"},{"name":"Department of Genetics, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shehla","family":"Admani","sequence":"additional","affiliation":[{"name":"Division of Pediatric Dermatology, Department of Dermatology, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Choate","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yale School of Medicine, New Haven, Connecticut"},{"name":"Department of Pathology, Yale School of Medicine, New Haven, Connecticut"},{"name":"Department of Genetics, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce M. C.","family":"Teng","sequence":"additional","affiliation":[{"name":"Division of Pediatric Dermatology, Department of Dermatology, Stanford University School of Medicine, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"3","key":"dlo180031r1","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.bjps.2010.05.033","article-title":"Surgical management of arteriovenous malformation.","volume":"64","author":"Visser","year":"2011","journal-title":"J Plast Reconstr Aesthet Surg"},{"issue":"4","key":"dlo180031r2","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1097\/PRS.0b013e3181d18070","article-title":"Extracranial arteriovenous malformations: natural progression and recurrence after treatment.","volume":"125","author":"Liu","year":"2010","journal-title":"Plast Reconstr Surg"},{"issue":"3","key":"dlo180031r3","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.ajhg.2017.01.018","article-title":"Somatic MAP2K1 mutations are associated with extracranial arteriovenous malformation.","volume":"100","author":"Couto","year":"2017","journal-title":"Am J Hum Genet"},{"issue":"4","key":"dlo180031r4","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1172\/JCI98589","article-title":"Mosaic RAS\/MAPK variants cause sporadic vascular malformations which respond to targeted therapy.","volume":"128","author":"Al-Olabi","year":"2018","journal-title":"J Clin Invest"},{"issue":"19","key":"dlo180031r5","doi-asserted-by":"publisher","first-page":"3007","DOI":"10.1182\/blood-2014-05-577825","article-title":"Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.","volume":"124","author":"Chakraborty","year":"2014","journal-title":"Blood"},{"key":"dlo180031r6","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/978-3-642-54490-3","article-title":"Trametinib.","volume":"201","author":"Zeiser","year":"2014","journal-title":"Recent Results Cancer Res"}],"container-title":["JAMA Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamadermatology\/fullarticle\/2718409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T23:52:16Z","timestamp":1550101936000},"score":1,"resource":{"primary":{"URL":"http:\/\/archderm.jamanetwork.com\/article.aspx?doi=10.1001\/jamadermatol.2018.4653"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,1]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,2,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamadermatol.2018.4653","relation":{},"ISSN":["2168-6068"],"issn-type":[{"value":"2168-6068","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2,1]]}}}