{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:07:44Z","timestamp":1777561664214,"version":"3.51.4"},"reference-count":27,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:sec id=\"ab-doi230025-4\"><jats:title>Importance<\/jats:title><jats:p>Patient preferences for pain medications after Mohs micrographic surgery are important to understand and have not been fully studied.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi230025-5\"><jats:title>Objective<\/jats:title><jats:p>To evaluate patient preferences for pain management with only over-the-counter medications (OTCs) or OTCs plus opioids after Mohs micrographic surgery given varying levels of theoretical pain and opioid addiction risk.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi230025-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This prospective discrete choice experiment was conducted in a single academic medical center from August 2021 to April 2022 among patients undergoing Mohs surgery and their accompanying support persons (\u226518 years). A prospective survey was administered to all participants using the Conjointly platform. Data were analyzed from May 2022 to February 2023.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi230025-7\"><jats:title>Main outcome and measure<\/jats:title><jats:p>The primary outcome was the pain level at which  half of the respondents chose OTCs plus opioids equally to only OTCs for pain management. This pain threshold was determined for varying opioid addiction risk profiles (low, 0%; low-moderate, 2%; moderate-high, 6%; high, 12%) and measured via a discrete choice experiment and linear interpolation of associated parameters (pain levels and risk of addiction).<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi230025-8\"><jats:title>Results<\/jats:title><jats:p>Of the 295 respondents (mean [SD] age, 64.6 [13.1] years; 174 [59%] were female; race and ethnicity were not considered) who completed the discrete choice experiment, 101 (34%) stated that they would never consider opioids for pain management regardless of the pain level experienced, and 147 (50%) expressed concern regarding possible opioid addiction. Across all scenarios, 224 respondents (76%) preferred only OTCs vs OTCs plus opioids after Mohs surgery for pain control. When the theoretical risk of addiction was low (0%), half of the respondents expressed a preference for OTCs plus opioids given pain levels of 6.5 on a 10-point scale (90% CI, 5.7-7.5). At higher opioid addiction risk profiles (2%, 6%, 12%), an equal preference for OTCs plus opioids and only OTCs was not achieved. In these scenarios, patients favored only OTCs despite experiencing high levels of pain.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi230025-9\"><jats:title>Conclusion and relevance<\/jats:title><jats:p>The findings of this prospective discrete choice experiment indicate that the perceived risk of opioid addiction affects the patient\u2019s choice of pain medications after Mohs surgery. It is important to engage patients undergoing Mohs surgery in shared decision-making discussions to determine the optimal pain control plan for each individual. These findings may encourage future research on the risks associated with long-term opioid use after Mohs surgery.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamadermatol.2023.1899","type":"journal-article","created":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T15:05:16Z","timestamp":1688569516000},"page":"848","source":"Crossref","is-referenced-by-count":6,"title":["Patient Preferences for Pain Control After Mohs Micrographic Surgery"],"prefix":"10.1001","volume":"159","author":[{"given":"Shannon T.","family":"Nugent","sequence":"first","affiliation":[{"name":"Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surya A.","family":"Veerabagu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University of New Mexico, Albuquerque"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Madden","sequence":"additional","affiliation":[{"name":"Brigham Young University, Provo, Utah"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arianna F.","family":"Yanes","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy R.","family":"Etzkorn","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph F.","family":"Sobanko","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thuzar M.","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"H. William","family":"Higgins","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacy L.","family":"McMurray","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna L.","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junqian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cerrene N.","family":"Giordano","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10","reference":[{"issue":"11","key":"doi230025r1","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1001\/jamadermatol.2021.3468","article-title":"Rates of opioid prescriptions obtained after Mohs surgery: a claims database analysis from 2009 to 2020.","volume":"157","author":"Veerabagu","year":"2021","journal-title":"JAMA Dermatol"},{"issue":"3","key":"doi230025r2","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1097\/DSS.0000000000002038","article-title":"Characteristics of opioid prescriptions by Mohs surgeons in the Medicare population.","volume":"46","author":"Feng","year":"2020","journal-title":"Dermatol Surg"},{"issue":"9","key":"doi230025r3","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1001\/jamainternmed.2016.3298","article-title":"Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period.","volume":"176","author":"Sun","year":"2016","journal-title":"JAMA Intern Med"},{"issue":"10","key":"doi230025r4","doi-asserted-by":"publisher","first-page":"1776","DOI":"10.1111\/j.1360-0443.2010.03052.x","article-title":"Risk factors for drug dependence among out-patients on opioid therapy in a large US health-care system.","volume":"105","author":"Boscarino","year":"2010","journal-title":"Addiction"},{"issue":"7","key":"doi230025r5","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.jpain.2007.02.432","article-title":"Substance use disorders in a primary care sample receiving daily opioid therapy.","volume":"8","author":"Fleming","year":"2007","journal-title":"J Pain"},{"issue":"9","key":"doi230025r7","doi-asserted-by":"publisher","first-page":"1202","DOI":"10.1016\/j.joca.2020.06.006","article-title":"Patient preferences for osteoarthritis pain and chronic low back pain treatments in the United States: a discrete-choice experiment.","volume":"28","author":"Turk","year":"2020","journal-title":"Osteoarthritis Cartilage"},{"issue":"6","key":"doi230025r8","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.jval.2018.12.010","article-title":"Patient preferences for endometriosis pain treatments in the United States.","volume":"22","author":"Poulos","year":"2019","journal-title":"Value Health"},{"issue":"5","key":"doi230025r9","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014719","article-title":"Do patients and health care providers have discordant preferences about which aspects of treatments matter most? 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