{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:00:35Z","timestamp":1792677635246,"version":"4.5.0"},"reference-count":152,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"<jats:sec id=\"ab-doi240021-1\"><jats:title>Importance<\/jats:title><jats:p>Seborrheic dermatitis is a prevalent chronic inflammatory skin disease, yet its global prevalence, pathogenesis, and epidemiology remain inadequately defined.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-2\"><jats:title>Objective<\/jats:title><jats:p>To provide a detailed estimation of the global prevalence of seborrheic dermatitis, analyze demographic variations, and explore differences in various settings.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-3\"><jats:title>Data Sources<\/jats:title><jats:p>Embase, PubMed, Scopus, and Cochrane Database of Systematic Reviews were searched from inception through October 2023.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-4\"><jats:title>Study Selection<\/jats:title><jats:p>Original investigations on seborrheic dermatitis prevalence were included after duplicate screening of titles, abstracts, and full articles, including only studies with clinician-diagnosed cases.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-5\"><jats:title>Data Extraction and Synthesis<\/jats:title><jats:p>Following PRISMA guidelines, data were extracted and quality was assessed independently by multiple reviewers. A random-effects model using restricted maximum likelihood was used for meta-analysis and subgroup analyses.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-6\"><jats:title>Main Outcome and Measure<\/jats:title><jats:p>The primary outcome was the pooled estimate of global seborrheic dermatitis prevalence.<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-7\"><jats:title>Results<\/jats:title><jats:p>From 1574 identified articles, 121 studies were included, encompassing 1\u202f260\u202f163 individuals and revealing a pooled global seborrheic dermatitis prevalence of 4.38% (95% CI, 3.58%-5.17%), with significant heterogeneity (<jats:italic>I<jats:sup>2<\/jats:sup><\/jats:italic>\u2009=\u200999.94%). Subgroup analyses showed variations by age, with a higher prevalence in adults (5.64% [95% CI, 4.01%-7.27%]) compared to children (3.70% [95% CI, 2.69%-4.80%]) and neonates (0.23% [95% CI, 0.04%-0.43%]). Geographic analyses indicated variability, with the highest prevalence in South Africa (8.82% [95% CI, 3.00%-14.64%]) and the lowest in India (2.62% [95% CI, 1.33%-3.92%]).<\/jats:p><\/jats:sec><jats:sec id=\"ab-doi240021-8\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>This comprehensive meta-analysis provides a detailed estimation of the global prevalence of seborrheic dermatitis, highlighting significant variability across different demographics and settings.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamadermatol.2024.1987","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T15:08:19Z","timestamp":1720019299000},"page":"846","source":"Crossref","is-referenced-by-count":63,"title":["The Global Prevalence of Seborrheic Dermatitis"],"prefix":"10.1001","volume":"160","author":[{"given":"Meredith Tyree","family":"Polaskey","sequence":"first","affiliation":[{"name":"Chicago Medical School, Rosalind Franklin University of Medicine and Science, 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