{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:47:34Z","timestamp":1768970854163,"version":"3.49.0"},"reference-count":6,"publisher":"American Medical Association (AMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"Importance<\/jats:title>Cutaneous squamous cell carcinoma (CSCC) is the second most common malignant disease in the US. Although it typically carries a good prognosis, a subset of CSCCs are highly aggressive, carrying regional and distant metastatic potential. Due to its high incidence, this aggressive subset is responsible for considerable mortality, with an overall annual mortality estimated to equal or even surpass melanoma. Despite this morbidity, CSCC is excluded from national cancer registries, making it difficult to study its epidemiology and outcomes. Therefore, the bulk of the CSCC literature is composed of single-center and multi-institutional retrospective cohort analyses. Given variations in reporting measures and analyses in these studies, interpretability between studies and the ability to pool results are limited.<\/jats:p><\/jats:sec>Objective<\/jats:title>To define standardized reporting measures for retrospective CSCC studies.<\/jats:p><\/jats:sec>Findings<\/jats:title>An expert panel was convened to determine standardized guidelines for recording and analyzing retrospective CSCC data. A total of 13 dermatologists and dermatologic surgeons with more than 5 years of posttraining experience and considerable experience with performing CSCC outcomes research were recruited to the panel. Consensus recommendations were achieved for CSCC retrospective study reporting measures, definitions, and analyses.<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>The recommendations in this report present the potential to standardize future CSCC retrospective studies. With such standardization, future work may have greater interstudy interpretability and allow for pooled analyses.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamadermatol.2024.2242","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T15:40:05Z","timestamp":1721835605000},"page":"989","source":"Crossref","is-referenced-by-count":5,"title":["Standardizing Retrospective Observational Research in Cutaneous Squamous Cell Carcinoma"],"prefix":"10.1001","volume":"160","author":[{"given":"Shayan","family":"Cheraghlou","sequence":"first","affiliation":[{"name":"The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary L.","family":"Stevenson","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean R.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy S.","family":"Bordeaux","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio"},{"name":"Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna L.","family":"Walker","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University of Texas Southwestern Medical Center, Dallas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Ferr\u00e1ndiz-Pulido","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin P.","family":"Bibee","sequence":"additional","affiliation":[{"name":"Departments of Dermatology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joi B.","family":"Carter","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faramarz H.","family":"Samie","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Columbia University Irving Medical Center, New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal A.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The George Washington University School of Medicine & Health Sciences, Washington, DC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan T.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Department of Dermatology, University Hospitals Cleveland Medical Center, Cleveland, Ohio"},{"name":"Department of Dermatology, Case Western Reserve University School of Medicine, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison T.","family":"Vidimos","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian L.","family":"Baum","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Mayo Clinic, Rochester, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin J.","family":"Leitenberger","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Oregon Health & Science University, Portland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anokhi","family":"Jambusaria-Pahlajani","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Internal Medicine, Dell Medical School at the University of Texas at Austin, Austin"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily S.","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Carucci","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman Department of Dermatology, New York University Grossman School of Medicine, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David R.","family":"Carr","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn T.","family":"Shahwan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus"},{"name":"Department of Internal Medicine, University of North Dakota Medical School, Grand Forks"},{"name":"Department of Dermatology, Altru Health System, Grand Forks, North Dakota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10","reference":[{"issue":"2","key":"dcs240008r1","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jaad.2017.08.059","article-title":"Cutaneous squamous cell carcinoma: incidence, risk factors, diagnosis, and staging.","volume":"78","author":"Que","year":"2018","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"dcs240008r2","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1016\/j.jaad.2012.11.037","article-title":"Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012.","volume":"68","author":"Karia","year":"2013","journal-title":"J Am Acad Dermatol"},{"issue":"5","key":"dcs240008r3","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/j.jaad.2016.06.047","article-title":"Defining recurrence of nonmelanoma skin cancer after Mohs micrographic surgery: report of the American College of Mohs Surgery Registry and Outcomes Committee.","volume":"75","author":"Leitenberger","year":"2016","journal-title":"J Am Acad Dermatol"},{"issue":"4","key":"dcs240008r5","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1001\/jamadermatol.2022.0001","article-title":"Implications of satellitosis or in-transit metastasis in cutaneous squamous cell carcinoma: a prognostic omission in cancer staging systems.","volume":"158","author":"Smile","year":"2022","journal-title":"JAMA Dermatol"},{"issue":"1","key":"dcs240008r6","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00403-023-02740-0","article-title":"Survival analyses in cutaneous squamous cell carcinoma: accounting for both competing risks and repeated measures.","volume":"316","author":"Nikahd","year":"2023","journal-title":"Arch Dermatol Res"},{"key":"dcs240008r4","volume-title":"AJCC Cancer Staging Manual","author":"Amin","year":"2018","edition":"8th ed"}],"container-title":["JAMA Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamadermatology\/articlepdf\/2821480\/jamadermatology_cheraghlou_2024_cs_240008_1726504999.24989.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,18]],"date-time":"2024-09-18T15:03:36Z","timestamp":1726671816000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamadermatology\/fullarticle\/2821480"}},"subtitle":["Expert Panel Guidelines from ITSCC"],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":6,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamadermatol.2024.2242","relation":{},"ISSN":["2168-6068"],"issn-type":[{"value":"2168-6068","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,1]]}}}