{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:20:42Z","timestamp":1792160442704,"version":"4.4.0"},"reference-count":47,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:sec id=\"ab-doi250055-4\">\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS\/TEN) survivors experience substantial long-term sequelae. Research on physical symptoms experienced during acute hospitalization is well documented, but limited studies have been completed on the long-term biopsychosocial effects of SJS\/TEN, particularly from the patient\u2019s perspective.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-doi250055-5\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To increase the understanding of the long-term complications of SJS\/TEN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-doi250055-6\">\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This qualitative investigation was completed from within a community-based study, the SJS Survivors Study, using a semistructured, in-depth interview guide to query participants about their SJS\/TEN experience postdischarge from the hospital. Interviews took place by phone from July 2021 through August 2023. This study included adults who experienced SJS\/TEN within the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-doi250055-7\">\n                    <jats:title>Main Outcome and Measures<\/jats:title>\n                    <jats:p>A biopsychosocial theory-based framework and hierarchical coding system were utilized to understand the long-term life impacts of survivors of SJS\/TEN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-doi250055-8\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The 29 participants, aged 26 to 76 years, were 66% female and 69% White and had experienced SJS\/TEN from a wide range of drugs. Patients experienced support while in the hospital, but once discharged, felt isolated and without support to understand the potential sustained impacts of SJS\/TEN in their lives and the lives of their family members. Patients experienced ongoing biological symptoms, such as skin issues, debilitating visual impairment, blindness, and lack of functional autonomy. Psychological impacts included symptoms of anxiety, obsessive thinking, flashbacks, and depression. Socially, some survivors expressed a sense of abandonment and described negative impacts on their careers. Survivors also expressed frustration and isolation with having to navigate posthospital care alone. There was a lack of preemptive discharge education and SJS\/TEN-specific planning. Lack of physician knowledge about SJS\/TEN was particularly noted and survivors turned to the internet for guidance instead of receiving direction from their physicians. Medical distrust among survivors was frequently noted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"ab-doi250055-9\">\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>The findings highlight the need for postdischarge care coordination among patients and their primary physicians, including mental health support. This care coordination should be arranged prior to discharge to ensure the availability of adequate support and optimal health outcomes. It is essential that clinicians and researchers prioritize the understanding of long-term sequelae of SJS\/TEN and improve current discharge education and protocols for patients and their families.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamadermatol.2025.4345","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T16:00:37Z","timestamp":1762963237000},"page":"24","source":"Crossref","is-referenced-by-count":5,"title":["Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis"],"prefix":"10.1001","volume":"162","author":[{"given":"Michelle D.","family":"Martin-Pozo","sequence":"first","affiliation":[{"name":"Center for Drug Safety and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Williams","sequence":"additional","affiliation":[{"name":"Center for Drug Safety and Immunology, Vanderbilt University Medical 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