{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:29:01Z","timestamp":1787153341896,"version":"build-2736575974"},"reference-count":52,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Dermatol"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"\n Importance<\/jats:title>\n Accessible and effective management of atopic dermatitis (AD) across geographic boundaries is important. Scalable, collaborative care models that integrate patients, primary care practitioners, and specialists remain an unmet need.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To determine whether an online, team-based connected health (TCH) model provides equivalent improvements in AD severity compared to in-person care.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n In this pragmatic, randomized clinical equivalence trial, 300 patients with AD were enrolled from 8 outpatient dermatology clinics in California from August 2019 to May 2024 and randomized 1:1 to online or in-person care. Eligible participants were at least 1 year old and had a physician diagnosis of AD, internet and photograph access, and established or new clinician care.<\/jats:p>\n <\/jats:sec>\n \n Intervention<\/jats:title>\n The TCH model provided asynchronous, online access to dermatologists. Dermatologists reviewed patients\u2019 clinical histories and photographs and provided assessments and treatment recommendations online. The control arm provided conventional, in-person care.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n The primary outcome was 12-month change in the EASI (Eczema Area and Severity Index); secondary outcomes were changes in the POEM (Patient-Oriented Eczema Measure) and validated vIGA (Investigator Global Assessment), assessed quarterly.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Among 300 adults and children with AD (mean [SD] age, 34.6 [17.7] years; 211 [70.3%] female), 149 were assigned to TCH and 151 to in-person care. The difference in mean change between the 2 groups was \u22120.01 (95% CI, \u22120.22 to 0.20) for the EASI, 0.38 (95% CI, 0.03-0.73) for the POEM, and 0.06 (95% CI, 0.00-0.11) for the vIGA. All differences fell within prespecified equivalence margins.<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this randomized clinical trial, the online TCH model resulted in equivalent improvements in AD signs and symptoms compared to in-person care. Telehealth models may serve as effective tools for managing chronic diseases like AD.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov Identifier:\n NCT03981926<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamadermatol.2026.1959","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T15:32:47Z","timestamp":1782315167000},"page":"795","source":"Crossref","is-referenced-by-count":0,"title":["Online vs In-Person Care for Atopic Dermatitis"],"prefix":"10.1001","volume":"162","author":[{"given":"April W.","family":"Armstrong","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles"},{"name":"Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa M.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles"},{"name":"John A. 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