{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T19:56:15Z","timestamp":1793822175366,"version":"4.6.1"},"reference-count":23,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Intern Med"],"published-print":{"date-parts":[[2018,11,1]]},"DOI":"10.1001\/jamainternmed.2018.4251","type":"journal-article","created":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T13:46:46Z","timestamp":1538574406000},"page":"1482","source":"Crossref","is-referenced-by-count":20,"title":["Association of Risk for Venous Thromboembolism With Use of Low-Dose Extended- and Continuous-Cycle Combined Oral Contraceptives"],"prefix":"10.1001","volume":"178","author":[{"given":"Jie","family":"Li","sequence":"first","affiliation":[{"name":"Division of Epidemiology, Office of Pharmacovigilance and Epidemiology, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genna","family":"Panucci","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Moeny","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Office of Pharmacovigilance and Epidemiology, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Division of Epidemiology, Office of Pharmacovigilance and Epidemiology, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith C.","family":"Maro","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sengwee","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Ying","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"1","key":"ioi180068r1","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1097\/AOG.0b013e3181cb50b5","article-title":"Practice Bulletin No. 110: noncontraceptive uses of hormonal contraceptives.","volume":"115","author":"ACOG","year":"2010","journal-title":"Obstet Gynecol"},{"issue":"6","key":"ioi180068r2","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.contraception.2012.05.017","article-title":"Types of combined oral contraceptives used by US women.","volume":"86","author":"Hall","year":"2012","journal-title":"Contraception"},{"issue":"1","key":"ioi180068r3","first-page":"59","article-title":"Risk of venous thromboembolism in women taking the combined oral contraceptive: a systematic review and meta-analysis.","volume":"45","author":"Bateson","year":"2016","journal-title":"Aust Fam Physician"},{"issue":"3","key":"ioi180068r4","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.ijgo.2010.12.003","article-title":"SOGC clinical practice guidelines: oral contraceptives and the risk of venous thromboembolism: an update: No. 252, December 2010.","volume":"112","author":"Reid","year":"2011","journal-title":"Int J Gynaecol Obstet"},{"issue":"2","key":"ioi180068r6","doi-asserted-by":"publisher","first-page":"21S","DOI":"10.1016\/S0010-7824(00)00147-5","article-title":"Venous thromboembolism and combined oral contraceptives: does the type of progestogen make a difference?","volume":"62","author":"Lawrenson","year":"2000","journal-title":"Contraception"},{"issue":"3","key":"ioi180068r8","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1002\/cpt.v99.3","article-title":"The FDA\u2019s sentinel initiative\u2014a comprehensive approach to medical product surveillance.","volume":"99","author":"Ball","year":"2016","journal-title":"Clin Pharmacol Ther"},{"key":"ioi180068r9","first-page":"1","article-title":"The US Food and Drug Administration\u2019s Mini-Sentinel program: status and direction.","volume":"21","author":"Platt","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ioi180068r10","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/pds.2336","article-title":"Design considerations, architecture, and use of the Mini-Sentinel distributed data system.","volume":"21","author":"Curtis","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ioi180068r11","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1002\/pds.2319","article-title":"A policy framework for public health uses of electronic health data.","volume":"21","author":"McGraw","year":"2012","journal-title":"Pharmacoepidemiol Drug Saf"},{"issue":"4","key":"ioi180068r12","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1007\/s10995-015-1878-8","article-title":"Surveillance of medication use during pregnancy in the Mini-Sentinel Program.","volume":"20","author":"Andrade","year":"2016","journal-title":"Matern Child Health J"},{"issue":"1","key":"ioi180068r13","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.vaccine.2015.09.087","article-title":"Evaluation of the risk of venous thromboembolism after quadrivalent human papillomavirus vaccination among US females.","volume":"34","author":"Yih","year":"2016","journal-title":"Vaccine"},{"issue":"7","key":"ioi180068r14","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.jclinepi.2010.10.004","article-title":"A combined comorbidity score predicted mortality in elderly patients better than existing scores.","volume":"64","author":"Gagne","year":"2011","journal-title":"J Clin Epidemiol"},{"issue":"6","key":"ioi180068r16","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1097\/EDE.0000000000000709","article-title":"Sentinel modular program for propensity score-matched cohort analyses: application to glyburide, glipizide, and serious hypoglycemia.","volume":"28","author":"Zhou","year":"2017","journal-title":"Epidemiology"},{"issue":"5","key":"ioi180068r17","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1002\/cpt.429","article-title":"Successful comparison of US Food and Drug Administration Sentinel analysis tools to traditional approaches in quantifying a known drug-adverse event association.","volume":"100","author":"Gagne","year":"2016","journal-title":"Clin Pharmacol Ther"},{"key":"ioi180068r18","first-page":"235","article-title":"The lowest-dose, extended-cycle combined oral contraceptive pill with continuous ethinyl estradiol in the United States: a review of the literature on ethinyl estradiol 20 \u00b5g\/levonorgestrel 100 \u00b5g + ethinyl estradiol 10 \u00b5g.","volume":"2","author":"Krishnan","year":"2010","journal-title":"Int J Womens Health"},{"issue":"3","key":"ioi180068r19","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1002\/ijgo.2018.141.issue-3","article-title":"A systematic review and meta-analysis of venous thrombosis risk among users of combined oral contraception.","volume":"141","author":"Dragoman","year":"2018","journal-title":"Int J Gynaecol Obstet"},{"key":"ioi180068r20","doi-asserted-by":"publisher","first-page":"d6423","DOI":"10.1136\/bmj.d6423","article-title":"Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9.","volume":"343","author":"Lidegaard","year":"2011","journal-title":"BMJ"},{"issue":"6","key":"ioi180068r21","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1046\/j.1365-2125.2000.00198.x","article-title":"A comparison of the risks of venous thromboembolic disease in association with different combined oral contraceptives.","volume":"49","author":"Farmer","year":"2000","journal-title":"Br J Clin Pharmacol"},{"key":"ioi180068r22","doi-asserted-by":"publisher","first-page":"d2151","DOI":"10.1136\/bmj.d2151","article-title":"Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data.","volume":"342","author":"Jick","year":"2011","journal-title":"BMJ"},{"key":"ioi180068r23","doi-asserted-by":"publisher","first-page":"d2139","DOI":"10.1136\/bmj.d2139","article-title":"Risk of venous thromboembolism in users of oral contraceptives containing drospirenone or levonorgestrel: nested case-control study based on UK General Practice Research Database.","volume":"342","author":"Parkin","year":"2011","journal-title":"BMJ"},{"key":"ioi180068r5","volume-title":"Medical Eligibility Criteria for Contraceptive Use","author":"World Health Organization (WHO)","year":"2009","edition":"4th ed"},{"key":"ioi180068r7","unstructured":"Lybrel [package insert]. Philadelphia, PA: Wyeth; 2016.https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/021864s007lbl.pdf. Accessed October 30, 2016."},{"key":"ioi180068r15","unstructured":"Sentinel. Combined Oral Contraceptives Containing Ethinyl Estradiol and Levonorgestrel and Venous Thromboembolism. https:\/\/www.sentinelinitiative.org\/drugs\/assessments\/combined-oral-contraceptives-containing-ethinyl-estradiol-and-levonorgestrel-and. Accessed June 14, 2018."}],"container-title":["JAMA Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2705081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,5]],"date-time":"2018-11-05T11:00:33Z","timestamp":1541415633000},"score":1,"resource":{"primary":{"URL":"http:\/\/archinte.jamanetwork.com\/article.aspx?doi=10.1001\/jamainternmed.2018.4251"}},"subtitle":["A Safety Study Using the Sentinel Distributed Database"],"short-title":[],"issued":{"date-parts":[[2018,11,1]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamainternmed.2018.4251","relation":{},"ISSN":["2168-6106"],"issn-type":[{"value":"2168-6106","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11,1]]}}}