{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:01:44Z","timestamp":1790517704862,"version":"4.1.0"},"reference-count":31,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Intern Med"],"published-print":{"date-parts":[[2022,2,1]]},"DOI":"10.1001\/jamainternmed.2021.7372","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T16:39:07Z","timestamp":1640018347000},"page":"165","source":"Crossref","is-referenced-by-count":121,"title":["Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients"],"prefix":"10.1001","volume":"182","author":[{"given":"Roman","family":"Reindl-Schwaighofer","sequence":"first","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Heinzel","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Mayrdorfer","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhea","family":"Jabbour","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Hofbauer","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Merrelaar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Eder","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florina","family":"Regele","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Doberer","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Spechtl","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin","family":"Aschauer","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Koblischke","sequence":"additional","affiliation":[{"name":"Center for Virology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Paschen","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farsad","family":"Eskandary","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Hu","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"\u00d6hler","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arshdeep","family":"Bhandal","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Kleibenb\u00f6ck","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahel I.","family":"Jagoditsch","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Reiskopf","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Heger","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology and Hygiene, Austrian Agency for Health and Food Safety, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Bond","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg A.","family":"B\u00f6hmig","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Strassl","sequence":"additional","affiliation":[{"name":"Division of Virology, Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Weseslindtner","sequence":"additional","affiliation":[{"name":"Center for Virology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Indra","sequence":"additional","affiliation":[{"name":"Institute for Medical Microbiology and Hygiene, Austrian Agency for Health and Food Safety, Vienna, Austria"},{"name":"Paracelsus Medical University of Salzburg, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith H.","family":"Aberle","sequence":"additional","affiliation":[{"name":"Center for Virology, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Binder","sequence":"additional","affiliation":[{"name":"Wiener Gesundheitsverbund, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Oberbauer","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Dialysis, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"6","key":"ioi210076r1","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1681\/ASN.2021010009","article-title":"Initial effects of COVID-19 on patients with ESKD.","volume":"32","author":"Weinhandl","year":"2021","journal-title":"J Am Soc Nephrol"},{"issue":"7","key":"ioi210076r2","doi-asserted-by":"publisher","first-page":"2522","DOI":"10.1111\/ajt.v21.7","article-title":"An early experience on the effect of solid organ transplant status on hospitalized COVID-19 patients.","volume":"21","author":"Nair","year":"2021","journal-title":"Am J Transplant"},{"issue":"8","key":"ioi210076r3","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1097\/01.TP.0000438024.10375.2d","article-title":"Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients.","volume":"97","author":"Cowan","year":"2014","journal-title":"Transplantation"},{"issue":"23","key":"ioi210076r4","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1056\/NEJMoa2101544","article-title":"Safety and efficacy of single-dose Ad26.CoV2.S vaccine against COVID-19.","volume":"384","author":"Sadoff","year":"2021","journal-title":"N Engl J Med"},{"issue":"8","key":"ioi210076r5","doi-asserted-by":"publisher","first-page":"2719","DOI":"10.1111\/ajt.v21.8","article-title":"Reduced humoral response to mRNA SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients without prior exposure to the virus.","volume":"21","author":"Grupper","year":"2021","journal-title":"Am J Transplant"},{"issue":"21","key":"ioi210076r6","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.1001\/jama.2021.7489","article-title":"Antibody response to 2-dose SARS-CoV-2 mRNA vaccine series in solid organ transplant recipients.","volume":"325","author":"Boyarsky","year":"2021","journal-title":"JAMA"},{"issue":"9","key":"ioi210076r7","doi-asserted-by":"publisher","first-page":"e94","DOI":"10.1097\/TP.0000000000003784","article-title":"Poor anti-SARS-CoV-2 humoral and T-cell responses after 2 injections of mRNA vaccine in kidney transplant recipients treated with belatacept.","volume":"105","author":"Chavarot","year":"2021","journal-title":"Transplantation"},{"issue":"9","key":"ioi210076r8","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1097\/TP.0000000000003824","article-title":"Immunogenicity and reactogenicity after SARS-CoV-2 mRNA vaccination in kidney transplant recipients taking belatacept.","volume":"105","author":"Ou","year":"2021","journal-title":"Transplantation"},{"issue":"8","key":"ioi210076r9","doi-asserted-by":"publisher","first-page":"2727","DOI":"10.1111\/ajt.v21.8","article-title":"Cellular and humoral response after MRNA-1273 SARS-CoV-2 vaccine in kidney transplant recipients.","volume":"21","author":"Cucchiari","year":"2021","journal-title":"Am J Transplant"},{"issue":"14","key":"ioi210076r10","doi-asserted-by":"crossref","DOI":"10.1172\/JCI150175","article-title":"Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients.","volume":"131","author":"Sattler","year":"2021","journal-title":"J Clin Invest"},{"issue":"1","key":"ioi210076r11","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1038\/s41467-021-23173-1","article-title":"Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice.","volume":"12","author":"Spencer","year":"2021","journal-title":"Nat Commun"},{"issue":"1","key":"ioi210076r12","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1080\/22221751.2021.1902245","article-title":"Heterologous prime-boost: breaking the protective immune response bottleneck of COVID-19 vaccine candidates.","volume":"10","author":"He","year":"2021","journal-title":"Emerg Microbes Infect"},{"issue":"10289","key":"ioi210076r13","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1016\/S0140-6736(21)01115-6","article-title":"Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data.","volume":"397","author":"Shaw","year":"2021","journal-title":"Lancet"},{"key":"ioi210076r14","doi-asserted-by":"crossref","DOI":"10.1016\/S2213-2600(21)00357-X","article-title":"Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study.","author":"Hillus","year":"2021","journal-title":"Lancet Respir Med"},{"issue":"9","key":"ioi210076r15","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1016\/S1473-3099(21)00420-5","article-title":"Heterologous prime-boost vaccination with ChAdOx1 nCoV-19 and BNT162b2.","volume":"21","author":"Tenbusch","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"ioi210076r16","doi-asserted-by":"crossref","DOI":"10.1001\/jama.2021.12339","article-title":"Antibody response after a third dose of the mRNA-1273 SARS-CoV-2 vaccine in kidney transplant recipients with minimal serologic response to 2 doses.","author":"Benotmane","year":"2021","journal-title":"JAMA"},{"issue":"9","key":"ioi210076r17","doi-asserted-by":"publisher","first-page":"1330","DOI":"10.7326\/L21-0282","article-title":"Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients: a case series.","volume":"174","author":"Werbel","year":"2021","journal-title":"Ann Intern Med"},{"issue":"7","key":"ioi210076r18","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1056\/NEJMc2108861","article-title":"Three doses of an mRNA COVID-19 Vaccine in solid-organ transplant recipients.","volume":"385","author":"Kamar","year":"2021","journal-title":"N Engl J Med"},{"issue":"13","key":"ioi210076r19","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1056\/NEJMc2111462","article-title":"Randomized trial of a third dose of mRNA-1273 vaccine in transplant recipients.","volume":"385","author":"Hall","year":"2021","journal-title":"N Engl J Med"},{"key":"ioi210076r20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinf.2021.09.013","article-title":"Antibody titers and protection against a SARS-CoV-2 infection.","author":"Dimeglio","year":"2021","journal-title":"J Infect"},{"key":"ioi210076r21","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-021-01540-1","article-title":"Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection.","author":"Feng","year":"2021","journal-title":"Nat Med"},{"issue":"8","key":"ioi210076r22","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1111\/ajt.v20.8","article-title":"Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients: a prospective observational trial.","volume":"20","author":"Doberer","year":"2020","journal-title":"Am J Transplant"},{"issue":"22","key":"ioi210076r23","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.1056\/NEJMoa2104840","article-title":"Thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination.","volume":"384","author":"Greinacher","year":"2021","journal-title":"N Engl J Med"},{"key":"ioi210076r24","article-title":"Humoral and cellular immunity to SARS-CoV-2 vaccination in renal transplant versus dialysis patients: A prospective, multicenter observational study using mRNA-1273 or BNT162b2 mRNA vaccine.","volume":"9","author":"Stumpf","year":"2021","journal-title":"Lancet Reg Health Eur"},{"issue":"3","key":"ioi210076r25","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1111\/tid.2016.18.issue-3","article-title":"Primary Epstein-Barr virus infection, seroconversion, and post-transplant lymphoproliferative disorder in seronegative renal allograft recipients: a prospective cohort study.","volume":"18","author":"Hosseini-Moghaddam","year":"2016","journal-title":"Transpl Infect Dis"},{"issue":"3","key":"ioi210076r26","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1111\/tid.2011.13.issue-3","article-title":"Risk factors for late-onset cytomegalovirus disease in donor seropositive\/recipient seronegative kidney transplant recipients who receive antiviral prophylaxis.","volume":"13","author":"Boudreault","year":"2011","journal-title":"Transpl Infect Dis"},{"issue":"5","key":"ioi210076r27","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1016\/j.cell.2013.10.034","article-title":"Temporal response of the human virome to immunosuppression and antiviral therapy.","volume":"155","author":"De Vlaminck","year":"2013","journal-title":"Cell"},{"issue":"9","key":"ioi210076r28","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.1038\/s41591-021-01464-w","article-title":"Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19\/mRNA vaccination.","volume":"27","author":"Schmidt","year":"2021","journal-title":"Nat Med"},{"issue":"5","key":"ioi210076r29","doi-asserted-by":"crossref","DOI":"10.1111\/tid.13705","article-title":"Clinical effectiveness of COVID-19 vaccination in solid organ transplant recipients.","volume":"23","author":"Aslam","year":"2021","journal-title":"Transpl Infect Dis"},{"issue":"27","key":"ioi210076r30","doi-asserted-by":"publisher","first-page":"2832","DOI":"10.1056\/NEJMcp041507","article-title":"Clinical practice: prevention of hepatitis B with the hepatitis B vaccine.","volume":"351","author":"Poland","year":"2004","journal-title":"N Engl J Med"},{"issue":"3","key":"ioi210076r31","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1056\/NEJMoa2035002","article-title":"REGN-COV2, a neutralizing antibody cocktail, in outpatients with COVID-19.","volume":"384","author":"Weinreich","year":"2021","journal-title":"N Engl J Med"}],"container-title":["JAMA Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/articlepdf\/2787200\/jamainternal_reindlschwaighofer_2021_oi_210076_1643648293.78029.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T16:16:16Z","timestamp":1644250576000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2787200"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2022,2,1]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamainternmed.2021.7372","relation":{},"ISSN":["2168-6106"],"issn-type":[{"value":"2168-6106","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,1]]}}}