{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:01:35Z","timestamp":1791763295006,"version":"4.3.4"},"reference-count":45,"publisher":"American Medical Association (AMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Intern Med"],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>High levels of health care professional (HCP) distress portend negative consequences for HCPs and health systems.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate whether a 13-week digital well-being training could improve Mexican HCP distress and well-being.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, Setting, and Participants<\/jats:title>\n                    <jats:p>This 2-arm randomized clinical trial was conducted between March 2023 and March 2024 with 13-week postintervention and 37-week follow-up end points. Participants included 2315 adults with no previous well-being training experience who worked in 762 participating health care facilities across 7 Mexican states. Participants were randomly assigned (1:1) using stratified permuted blocks to well-being training or wait-list control. Outcomes assessors and study data analyst were masked to condition assignment. Assessments and intervention were conducted remotely.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>The digital well-being training consisted of nine 2-hour zoom sessions and 13 weeks of the Healthy Minds Program smartphone app structured on the premise that well-being skills can be strengthened through psychoeducation and contemplative practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcomes<\/jats:title>\n                    <jats:p>\n                      The primary prespecified outcomes were participant-reported distress (aggregate of\n                      <jats:italic>z<\/jats:italic>\n                      -scored National Institutes of Health Toolbox perceived stress, and Perceived Stress and Patient Reported Outcomes Measurement Information System anxiety and depression scales; mean\u2009=\u20090, SD\u2009=\u20091) and the World Health Organization\u20135 measure of well-being (range 0-25).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 2315 participants, 1693 (73.1%) identified as female; 778 (33.4%) nurses, 736 (31.7%) physicians, 187 (8.1%) psychologists, 183 (7.9%) administrators, 154 (6.7%) dentists, 75 (3.2%) social workers, 64 (2.8%) nutritionists, 55 (2.4%) laboratory technicians, 40 (1.7%) physical therapists, 29 (1.3%) health promoters, and 8 (&amp;amp;lt;0.1%) other health professionals; the mean (SD) age was 34.7 (11.4) years. Relative to control, in intention-to-treat analyses the intervention group reported 13-week reductions in distress (adjusted standardized mean difference [SMD], \u22120.24; 95% CI, \u22120.32 to \u22120.16) and increases in well-being (adjusted SMD, 0.27; 95% CI, 0.18 to 0.35) that increased in magnitude at 37-week follow-up (distress, \u22120.36; 95% CI, \u22120.44 to \u22120.28; well-being, 0.42; 95% CI, 0.34 to 0.50). Primary outcomes were robust in sensitivity analyses. There were 10 adverse events (intervention: 0.05% [6 of 1157]; control: 0.04% [4 of 1158]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Relevance<\/jats:title>\n                    <jats:p>This randomized clinical trial found that scalable digital well-being training modestly improved Mexican HCP distress and well-being compared with a wait-list condition. As HCPs are essential to public health and report high levels of distress that interfere with their ability to provide optimal care, well-being training may be an avenue to better supporting HCPs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      ClinicalTrials.gov Identifier:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\/study\/NCT05767970\">NCT05767970<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1001\/jamainternmed.2025.3888","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T15:31:14Z","timestamp":1755531074000},"page":"1248","source":"Crossref","is-referenced-by-count":10,"title":["Digital Well-Being Training With Health Care 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