{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:43:12Z","timestamp":1791996192032,"version":"4.4.0"},"reference-count":21,"publisher":"American Medical Association (AMA)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Intern Med"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"\n Importance<\/jats:title>\n Heart failure (HF) is a common complication of type 2 diabetes (T2D). Oral semaglutide reduced the risk of major adverse cardiovascular (CV) events (MACE; comprising CV death, nonfatal myocardial infarction, or nonfatal stroke) in people with T2D in the SOUL trial, but the impact on HF outcomes in these participants is unknown.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate the effect of oral semaglutide on HF events, MACE, and safety among participants with or without HF at baseline.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This is a secondary analysis of the double-blind, placebo-controlled, event-driven, phase 3b SOUL randomized clinical trial, which was conducted at 444 centers in 33 countries. Participants were enrolled from June 17, 2019, to March 24, 2021, and had T2D and atherosclerotic CV disease and\/or chronic kidney disease, stratified according to the presence or absence of HF history at baseline. Data were analyzed from December 2024 to August 2025.<\/jats:p>\n <\/jats:sec>\n \n Intervention<\/jats:title>\n Once-daily oral semaglutide or placebo in addition to standard of care.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n Prespecified composite HF outcome (time to first occurrence of HF hospitalization, urgent HF visit, or CV death).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Overall, 9650 participants (median [IQR] age, 66.0 [61.0-72.0] years; 2790 [28.9%] female) were randomized, with a mean (SD) follow-up of 47.5 (10.9) months. Of these participants, 2229 (23.1%) had HF history (991 [10.3%] with preserved ejection fraction, 592 [6.1%] with reduced ejection fraction, and 646 [6.7%] with unknown subtype). For participants with HF at baseline, the hazard ratio (HR) for risk of the composite HF outcome with oral semaglutide vs placebo was 0.78 (95% CI, 0.63-0.96) and was 1.01 (95% CI, 0.84-1.20) in those without HF at baseline (\n P<\/jats:italic>\n for interaction\u2009=\u2009.06). Among participants with HF, the HR was 0.59 (95% CI, 0.39-0.86) in those with preserved ejection fraction and 0.98 (95% CI, 0.70-1.38) in those with reduced ejection fraction. There was no heterogeneity in the risk reduction of MACE with oral semaglutide in participants with HF history (HR, 0.83; 95% CI, 0.68-1.01) or without HF history (HR, 0.86; 95% CI, 0.75-0.98) (\n P<\/jats:italic>\n for interaction\u2009=\u2009.77). Serious adverse event occurrence among participants with HF was similar with oral semaglutide (594 [53.8%]) and placebo (642 [57.1%]).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this secondary analysis of the SOUL randomized clinical trial, among individuals with T2D, atherosclerotic CV disease, and\/or chronic kidney disease, a reduction of HF events was observed with use of oral semaglutide compared with placebo in those with a history of HF, without increasing the risk of serious adverse events. These data support the potential benefit of oral semaglutide in reducing HF events in people with T2D and HF.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov Identifier:\n NCT03914326<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamainternmed.2025.7774","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T16:00:30Z","timestamp":1770048030000},"page":"426","source":"Crossref","is-referenced-by-count":14,"title":["Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes"],"prefix":"10.1001","volume":"186","author":[{"given":"Rodica","family":"Pop-Busui","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Medicine, Oregon Health & Science University, Portland"},{"name":"Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical School, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Deanfield","sequence":"additional","affiliation":[{"name":"Institute of Cardiovascular Sciences, University College London, London, England, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John B.","family":"Buse","sequence":"additional","affiliation":[{"name":"University of North Carolina School of Medicine, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus","family":"Marx","sequence":"additional","affiliation":[{"name":"Clinic for Cardiology, Angiology, and Intensive Care Medicine, RWTH Aachen University, University Hospital Aachen, Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon L.","family":"Mulvagh","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio E.","family":"Inzucchi","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes F. E.","family":"Mann","sequence":"additional","affiliation":[{"name":"KfH Kidney Center, Munich, Germany"},{"name":"Friedrich Alexander University of Erlangen, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott S.","family":"Emerson","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, School of Public Health, University of Washington, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil R.","family":"Poulter","sequence":"additional","affiliation":[{"name":"Imperial Clinical Trials Unit, Faculty of Medicine, Imperial College London, London, England, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mads D. M.","family":"Engelmann","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Kees","family":"Hovingh","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrine","family":"Bayer Tanggaard","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas L.","family":"Birkenfeld","sequence":"additional","affiliation":[{"name":"Department of Diabetology, Endocrinology and Nephrology, University Hospital T\u00fcbingen, T\u00fcbingen, Germany"},{"name":"Institute for Diabetes Research and Metabolic Diseases of Helmholtz Munich, Eberhard Karls University of T\u00fcbingen, T\u00fcbingen, Germany"},{"name":"German Center for Diabetes Research (DZD), T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim A.","family":"Connelly","sequence":"additional","affiliation":[{"name":"Keenan Research Centre for Biomedical Science, Departments of Medicine and Cardiology, St Michael\u2019s Hospital, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Haluzik","sequence":"additional","affiliation":[{"name":"Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czechia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew A.","family":"Cavender","sequence":"additional","affiliation":[{"name":"University of North Carolina School of Medicine, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Kellerer","sequence":"additional","affiliation":[{"name":"Department of Diabetology and Endocrinology, Clinic for Internal Medicine, Marienhospital Stuttgart, Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pardeep S.","family":"Jhund","sequence":"additional","affiliation":[{"name":"British Heart Foundation Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, Scotland, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Gregersen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Aarhus, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olav Wendelboe","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn S. P.","family":"Lam","sequence":"additional","affiliation":[{"name":"National Heart Centre Singapore, Outram, Singapore"},{"name":"Duke\u2013National University of Singapore, Outram, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren K.","family":"McGuire","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Parkland Health System, Dallas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"SOUL Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Schelde","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aslam","family":"Amod","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borys","family":"Mankovsky","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus V.","family":"Desouza","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"Gorgojo-Martinez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Arechavaleta","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Te","family":"Tu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Francisco","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robinson","family":"S\u00e1nchez Garc\u00eda","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Chun Chung Chow","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Watada","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun Ho","family":"Yoon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Perez Manghi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose M.","family":"Pozzi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto J.","family":"Lorenzatti","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia E.","family":"Visco","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Piskorz","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucrecia","family":"Nardone","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano I.","family":"Chahin","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Bustamante Labarta","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Luquez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio J.","family":"MacKinnon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pieber","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Prager","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn","family":"Flie\u00dfer-G\u00f6rzer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Ebenbichler","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Fasching","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Mathieu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"De Block","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Duyck","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen","family":"Heyns","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Lapauw","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz A. A.","family":"Turatti","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise R.","family":"Franco","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosangela R.","family":"Rea","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo R.","family":"Kurtz Lisboa","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o E.","family":"Salles","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 F. K.","family":"Saraiva","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto G. T.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria H.","family":"Vidotti","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silmara O.","family":"Leite","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naresh","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet","family":"Bajaj","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Schlosser","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Noronha","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Pedersen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guy","family":"Tellier","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Weisnagel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorin","family":"Beca","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hani","family":"Alasaad","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zubin","family":"Punthakee","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G. B.","family":"Mancini","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Tytus","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas P. P.","family":"Ransom","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mansoor","family":"Husain","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Tsoukas","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linong","family":"Ji","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoyue","family":"Yuan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhua","family":"Ye","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"Dong","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Bian","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Angelo Cadena Bonfanti","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan D.","family":"Hernandez Erazo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eder A.","family":"Hern\u00e1ndez Ruiz","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan E.","family":"G\u00f3mez Mesa","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvija","family":"Canecki-Varzic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Vucak Loncar","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Simegi-Djekic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Ticinovic Kurir","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srecko","family":"Tusek","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Rahelic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srecko","family":"Marusic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Kruljac","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Fabris Vitkovic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Oznerova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Vrkoc","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbora","family":"Dole\u017ealov\u00e1","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdenek","family":"Jankovec","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jindrich","family":"Olsovsky","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitka","family":"Zemanova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavlina","family":"Kyselova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"\u0160mahelov\u00e1","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ane Mette Z.","family":"Olsen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Mikkelsen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Egstrup","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrik","family":"Pedersen-Bjergaard","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Potier","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Borot","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedicte","family":"Gaborit","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Monier","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Pradignac","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Verges","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Larroumet","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Francois","family":"Thuan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"L\u00fcdemann","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Esser","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Kahrmann","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Kempe","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Koch","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Axthelm","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Paschen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludger","family":"Rose","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schaum","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Schulze","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Staudenmeyer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Wenzl-Bauer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald C. W.","family":"Ma","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihal","family":"Thomas","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Mohan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Sekhar","family":"Reddy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paturi V.","family":"Rao","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Sahay","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasminder","family":"Singh","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupam","family":"Prakash","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Tandon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiven","family":"Marwah","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tirthankar","family":"Chaudhury","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujoy","family":"Ghosh","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alok K.","family":"Kanungo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen","family":"Mittal","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jubbin J.","family":"Jacob","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Chadha","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil M.","family":"Bhagwat","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil M.","family":"Jain","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. K.","family":"Thulaseedharan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopalakrishnan","family":"Girithara","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Desai","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. K.","family":"Sharma","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreenivasa","family":"Murthy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bipin K.","family":"Sethi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Kadam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jothydev","family":"Kesavadev","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bipin","family":"Daxini","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeev","family":"Chawla","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Unnikrishnan A.","family":"Gopalakrishnan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manash P.","family":"Baruah","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhakar P.","family":"Reddy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. M.","family":"Suryanarayana","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran P.","family":"Singh","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Banshi","family":"Saboo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genya","family":"Aharon-Hananel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irit","family":"Hochberg","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Sofer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Tirosh","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan","family":"Shimon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Vishlitzky","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Bashkin","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anat","family":"Tsur","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Shechter","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Andreozzi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Setola","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agostino","family":"Consoli","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Lupoli","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Genovese","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Maranghi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Lauro","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Citarrella","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Paolo","family":"Fadini","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Murdolo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Di Carlo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Giorgino","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Buscemi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Hanaoka","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Osonoi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ohashi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Ezaki","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhito","family":"Yuki","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arihiro","family":"Kiyosue","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Hata","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Sugawara","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Domae","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Iwata","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuya","family":"Nishida","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Igarashi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susumu","family":"Fujino","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ako","family":"Oiwa","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiki","family":"Oh","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Sueyoshi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Murakami","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhei","family":"Tanaka","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Idogaki","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Onaka","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isamu","family":"Mizote","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Doi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Ebisui","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makito","family":"Tanabe","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Natsuaki","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Jinnouchi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Nakamura","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan Mohd Izani","family":"Wan Mohamed","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norhayati","family":"Yahaya","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeyakantha","family":"Ratnasingam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiong Kiam","family":"Ong","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masni","family":"Mohamad","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Shaffinaz","family":"Yusoff Azmi Merican","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohana","family":"Abdul Ghani","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor Lita","family":"Adam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tem Lom","family":"Fam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence H. S.","family":"Tan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique C.","family":"Morales Villegas","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Gonzalez-Galvez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Espinoza Peralta","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos E.","family":"Medina Pech","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana C.","family":"Garc\u00eda Ulloa","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo A.","family":"Laviada Molina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramiro G.","family":"Banda Elizondo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 \u00c1.","family":"Garza Ruiz","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u00edas A.","family":"Garc\u00eda Cant\u00fa","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"van Bemmel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold W.","family":"de Valk","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriaan","family":"Kooy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Lieverse","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. A. N. T.","family":"Landewe-Cleuren","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaas","family":"Hoogenberg","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"van Raalte","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Jebbink","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Oldenburg-Ligtenberg","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evertine","family":"Abbink-Zandbergen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan","family":"Mihai","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Crisan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuliana","family":"Filip","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela M.","family":"Busegeanu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Roman","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina C.","family":"Mot","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Nicoara","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Anghel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemi N.","family":"Pletea","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirela","family":"Suciu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Strajer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Cernea","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexei","family":"Zilov","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanna","family":"Kobalava","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludmila A.","family":"Ruyatkina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmila A.","family":"Suplotova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Y.","family":"Sergeeva-Kondrachenko","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria E.","family":"Yanovskaya","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubov","family":"Kargina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ignatyeva","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khavra","family":"Astamirova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alsu","family":"Zalevskaya","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Zagrebelnaya","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena V.","family":"Frolova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey B.","family":"Peskov","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Mishchenko (Golinskaya)","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Otroshchenko","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leylya","family":"Gaysina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olesya Y.","family":"Shabelnikova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana V.","family":"Saprina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatyana A.","family":"Lysenko","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Kunitsyna","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana T.","family":"Zyangirova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebojsa","family":"Lalic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Lalic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodora","family":"Beljic Zivkovic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasa","family":"Kikovic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar","family":"Djukic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milica","family":"Pesic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragan","family":"Dimic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edita","family":"Stokic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Mitrovic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Snezana","family":"Polovina","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miodrag","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalibor","family":"Sosovec","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Pella","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viera","family":"Donicova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Hanackova Prasekova","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Koleny","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Culak","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Cerna","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor","family":"Hundza","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juraj","family":"Gmitrov","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jozef","family":"Lacka","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radovan","family":"Plasil","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajira B.","family":"Bacus","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qasim E.","family":"Bhorat","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Joshi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak R.","family":"Lakha","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikash","family":"Makan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ntobeko","family":"Ntusi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevenesan","family":"Padayachee","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Seeber","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deenadayalan","family":"Pillay","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukesh","family":"Joshi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Mayet","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joonyub","family":"Lee","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sin Gon","family":"Kim","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KyungWan","family":"Min","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Seok","family":"Kang","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woo Je","family":"Lee","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Hee","family":"Choi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Beom","family":"Lee","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"L\u00f3pez Su\u00e1rez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel \u00c1ngel","family":"Garc\u00eda Ord\u00f3\u00f1ez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Garc\u00eda Quintana","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Maz\u00f3n Ramos","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Secundino","family":"Cigarr\u00e1n","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Barrios","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Soto Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esteban","family":"Jodar","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Delgado Lista","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristobal","family":"Morales Portillo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coral","family":"Montalb\u00e1n Carrasco","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Tinahones","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Ning","family":"Huang","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu-Tah","family":"Chen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patinut","family":"Buranasupkajorn","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apiradee","family":"Sriwijitkamol","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supawan","family":"Buranapin","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisara","family":"Suwanagool","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puntip","family":"Tantiwong","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apussanee","family":"Boonyavarakul","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunun","family":"Benjachareonwong","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rattana","family":"Leelawattana","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prin","family":"Vathesatogkit","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaicharn","family":"Deerochanawong","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf A.","family":"Sonmez","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aytekin","family":"Oguz","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omur","family":"Tabak","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Kocak","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Sariakcali","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahri","family":"Bayram","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metin","family":"Guclu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eren","family":"Gurkan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur","family":"Kebapci","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdurrahman","family":"Comlekci","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fettah","family":"Acibucu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suleyman","family":"Ahbab","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Habib","family":"Bilen","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Urbanovych","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petro","family":"Kuskalo","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iryna","family":"Bondarets","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olena","family":"Petrosyan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataliia","family":"Pashkovska","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Oleksyk","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Kaydashev","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kateryna","family":"Maliar","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Galyna","family":"Myshanych","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen C.","family":"Bain","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan","family":"Black","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Johnston","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuong","family":"Dang","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ketan","family":"Dhatariya","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"English","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Field","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Grimmer","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Gunstone","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutapa","family":"Ray","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijela","family":"Tatovic","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Kernohan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Lindsay","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Mcknight","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Park","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipesh","family":"Patel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Philip","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpal","family":"Randeva","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thozhukat","family":"Sathyapalan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Turner","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nell","family":"Wyatt","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale C.","family":"Allison","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivex","family":"Awasty","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsegenet","family":"Ayele","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Bajaj","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Budoff","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Busch","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Casaubon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushela S.","family":"Chaidarun","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald H.","family":"Chochinov","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Chu","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nizar Y.","family":"Daboul","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy H.","family":"Dang","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G.","family":"Everhart","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Arambasick","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond I.","family":"Fink","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Fitz-Patrick","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles M.","family":"Fogarty","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew P.","family":"Gilbert","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Johnson","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sathya S.","family":"Krishnasamy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy S.","family":"Lane","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samer N.","family":"Nakhle","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Levenson","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"O\u2019Donnell","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Weiss","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Risser","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Wierum","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanagaratnam","family":"Sivalingam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Gupta","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athena","family":"Philis-Tsimikas","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Pratley","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubna","family":"Mirza","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Snyder","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Rasouli","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Porter","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert N.","family":"Ledesma","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talessa","family":"Powell","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ileana J.","family":"Tandron","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildiko","family":"Lingvay","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"John C. H.","family":"Reed","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minesh B.","family":"Patel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragana","family":"Lovre","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tira","family":"Chaicha-Brom","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis","family":"Jantzi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Brautigam","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shichun","family":"Bao","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline N.","family":"Mbogua","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard R.","family":"Zemel","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Hasan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Rosenstock","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hien","family":"Tran","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Poremba","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Baker","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Prier","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna","family":"Chilka","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Agaiby","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Condit","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald C.","family":"Eagerton","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Huffman","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M.","family":"Cornett","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Traylor","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Brinson","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold E.","family":"Bays","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terri","family":"Jerkins","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip R.","family":"Nicol","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imran A.","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitzie","family":"Hewitt","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeniyi O.","family":"Odugbesan","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J,","family":"Lillestol","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Thrasher","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Winston H.","family":"Gandy","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Pant","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Nagelberg","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Cannon","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marshall W.","family":"Anderson","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuj","family":"Bhargava","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Doshi","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael F.","family":"Jardula","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Montero","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raman S.","family":"Purighalla","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark L.","family":"Warren","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Harris","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Jackson","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit S.","family":"Khaira","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Gonzalez-Orozco","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Gagianas","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Pantalone","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander V.","family":"Murray","sequence":"additional","affiliation":[{"name":"for the SOUL Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","reference":[{"issue":"7","key":"ioi250094r1","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.2337\/dci22-0014","article-title":"Heart failure: an underappreciated complication of diabetes: a consensus report of the American Diabetes Association.","volume":"45","author":"Pop-Busui","year":"2022","journal-title":"Diabetes Care"},{"issue":"24","key":"ioi250094r2","doi-asserted-by":"publisher","first-page":"2774","DOI":"10.1161\/CIRCULATIONAHA.118.034986","article-title":"Incidence of hospitalization for heart failure and case-fatality among 3.25 million people with and without diabetes mellitus.","volume":"138","author":"McAllister","year":"2018","journal-title":"Circulation"},{"issue":"1","key":"ioi250094r3","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12933-021-01344-0","article-title":"CAPTURE: a multinational, cross-sectional study of cardiovascular disease prevalence in adults with type 2 diabetes across 13 countries.","volume":"20","author":"Mosenzon","year":"2021","journal-title":"Cardiovasc Diabetol"},{"issue":"9","key":"ioi250094r4","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1007\/s00125-019-4926-x","article-title":"Diabetes as a risk factor for heart failure in women and men: a systematic review and meta-analysis of 47 cohorts including 12 million individuals.","volume":"62","author":"Ohkuma","year":"2019","journal-title":"Diabetologia"},{"issue":"1","key":"ioi250094r5","doi-asserted-by":"publisher","first-page":"107","DOI":"10.2991\/jegh.k.191028.001","article-title":"Epidemiology of type 2 diabetes\u2014global burden of disease and forecasted trends.","volume":"10","author":"Khan","year":"2020","journal-title":"J Epidemiol Glob Health"},{"key":"ioi250094r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2023.111054","article-title":"Diabetes and risk of heart failure in people with and without cardiovascular disease: systematic review and meta-analysis.","volume":"207","author":"Panchal","year":"2024","journal-title":"Diabetes Res Clin Pract"},{"issue":"5","key":"ioi250094r7","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1002\/ejhf.1170","article-title":"Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology.","volume":"20","author":"Seferovic","year":"2018","journal-title":"Eur J Heart Fail"},{"issue":"7","key":"ioi250094r8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.119.006260","article-title":"Type 2 diabetes mellitus and impact of heart failure on prognosis compared to other cardiovascular diseases: a nationwide study.","volume":"13","author":"Zareini","year":"2020","journal-title":"Circ Cardiovasc Qual Outcomes"},{"issue":"5","key":"ioi250094r9","doi-asserted-by":"publisher","first-page":"846","DOI":"10.2337\/dc25-0241","article-title":"Cardiovascular and kidney outcomes and mortality with long-acting injectable and oral glucagon-like peptide 1 receptor agonists in individuals with type 2 diabetes: a systematic review and meta-analysis of randomized trials.","volume":"48","author":"Lee","year":"2025","journal-title":"Diabetes Care"},{"issue":"10456","key":"ioi250094r10","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/S0140-6736(24)01643-X","article-title":"Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials.","volume":"404","author":"Kosiborod","year":"2024","journal-title":"Lancet"},{"issue":"17","key":"ioi250094r11","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1016\/j.jacc.2024.08.004","article-title":"Effects of semaglutide on heart failure outcomes in diabetes and chronic kidney disease in the FLOW trial.","volume":"84","author":"Pratley","year":"2024","journal-title":"J Am Coll Cardiol"},{"issue":"10454","key":"ioi250094r12","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1016\/S0140-6736(24)01498-3","article-title":"Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial.","volume":"404","author":"Deanfield","year":"2024","journal-title":"Lancet"},{"issue":"20","key":"ioi250094r13","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1056\/NEJMoa2501006","article-title":"Oral semaglutide and cardiovascular outcomes in high-risk type 2 diabetes.","volume":"392","author":"McGuire","year":"2025","journal-title":"N Engl J Med"},{"issue":"7","key":"ioi250094r14","doi-asserted-by":"publisher","first-page":"1932","DOI":"10.1111\/dom.15058","article-title":"Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and\/or chronic kidney disease: design and baseline characteristics of SOUL, a randomized trial.","volume":"25","author":"McGuire","year":"2023","journal-title":"Diabetes Obes Metab"},{"issue":"12","key":"ioi250094r16","doi-asserted-by":"publisher","first-page":"2368","DOI":"10.1016\/j.jacc.2004.09.033","article-title":"Sympathetic dysfunction in type 1 diabetes: association with impaired myocardial blood flow reserve and diastolic dysfunction.","volume":"44","author":"Pop-Busui","year":"2004","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"ioi250094r17","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.jacc.2012.10.028","article-title":"Association between cardiovascular autonomic neuropathy and left ventricular dysfunction: DCCT\/EDIC study (Diabetes Control and Complications Trial\/Epidemiology of Diabetes Interventions and Complications).","volume":"61","author":"Pop-Busui","year":"2013","journal-title":"J Am Coll Cardiol"},{"issue":"5","key":"ioi250094r18","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.jacc.2018.11.033","article-title":"Heart failure with preserved ejection fraction and diabetes: JACC state-of-the-art review.","volume":"73","author":"McHugh","year":"2019","journal-title":"J Am Coll Cardiol"},{"issue":"18","key":"ioi250094r19","doi-asserted-by":"publisher","first-page":"1810","DOI":"10.1016\/j.jacc.2023.01.049","article-title":"Heart failure with preserved ejection fraction: JACC scientific statement.","volume":"81","author":"Borlaug","year":"2023","journal-title":"J Am Coll Cardiol"},{"issue":"18","key":"ioi250094r20","doi-asserted-by":"publisher","first-page":"e895","DOI":"10.1161\/CIR.0000000000001063","article-title":"2022 AHA\/ACC\/HFSA Guideline for the Management of Heart Failure: a report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines.","volume":"145","author":"Heidenreich","year":"2022","journal-title":"Circulation"},{"issue":"5","key":"ioi250094r21","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1056\/NEJMoa2410027","article-title":"Tirzepatide for heart failure with preserved ejection fraction and obesity.","volume":"392","author":"Packer","year":"2025","journal-title":"N Engl J Med"},{"key":"ioi250094r15","doi-asserted-by":"crossref","DOI":"10.1002\/9780470316696","volume-title":"Multiple Imputation for Nonresponse in Surveys","author":"Rubin","year":"1987"}],"container-title":["JAMA Internal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/articlepdf\/2844096\/jamainternal_popbusui_2026_oi_250094_1774053171.98221.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T15:01:11Z","timestamp":1775487671000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2844096"}},"subtitle":["A Secondary Analysis of the SOUL Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamainternmed.2025.7774","relation":{},"ISSN":["2168-6106"],"issn-type":[{"value":"2168-6106","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4,1]]}}}