{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:49:12Z","timestamp":1790858952823,"version":"4.1.0"},"reference-count":30,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2018.7235","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T11:31:08Z","timestamp":1547811068000},"page":"e187235","source":"Crossref","is-referenced-by-count":128,"title":["Association of Infants Exposed to Prenatal Zika Virus Infection With Their Clinical, Neurologic, and Developmental Status Evaluated via the General Movement Assessment Tool"],"prefix":"10.1001","volume":"2","author":[{"given":"Christa","family":"Einspieler","sequence":"first","affiliation":[{"name":"Interdisciplinary Developmental Neuroscience\u2013iDN, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"Utsch","sequence":"additional","affiliation":[{"name":"Rede SARAH de Hospitais de Reabilita\u00e7\u00e3o, Reabilita\u00e7\u00e3o Infantil, Belo Horizonte, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Brasil","sequence":"additional","affiliation":[{"name":"Laboratorio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas (INI), Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Y.","family":"Panvequio Aizawa","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Communication Sciences & Disorders, and Occupational Therapy, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Peyton","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy and Human Movement Science, Northwestern University, Chicago, Illinois"},{"name":"Department of Pediatrics, University of Chicago, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Hydee Hasue","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Communication Sciences & Disorders, and Occupational Therapy, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Fran\u00e7oso Genovesi","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Communication Sciences & Disorders, and Occupational Therapy, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luana","family":"Damasceno","sequence":"additional","affiliation":[{"name":"Laboratorio de Doen\u00e7as Febris Agudas, Instituto Nacional de Infectologia Evandro Chagas (INI), Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elisabeth","family":"Moreira","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Instituto Fernandes Figueira, Fiocruz, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Adachi","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Marschik","sequence":"additional","affiliation":[{"name":"Interdisciplinary Developmental Neuroscience\u2013iDN, Medical University of Graz, Graz, Austria"},{"name":"Interdisciplinary Developmental Neuroscience\u2013iDN, Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Center G\u00f6ttingen, G\u00f6ttingen, Germany"},{"name":"Center of Neurodevelopmental Disorders (KIND), Department of Women\u2019s and Children\u2019s Health, Karolinska Institutet, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Nielsen-Saines","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the GM Zika Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2019,1,18]]},"reference":[{"issue":"31","key":"zoi180301r1","doi-asserted-by":"publisher","first-page":"858","DOI":"10.15585\/mmwr.mm6731e1","article-title":"Vital Signs: Zika-associated birth defects and neurodevelopmental abnormalities possibly associated with congenital Zika virus infection: U.S. territories and freely associated states, 2018.","volume":"67","author":"Rice","year":"2018","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"24","key":"zoi180301r2","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1056\/NEJMoa1602412","article-title":"Zika virus infection in pregnant women in Rio de Janeiro.","volume":"375","author":"Brasil","year":"2016","journal-title":"N Engl J Med"},{"issue":"1","key":"zoi180301r3","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1097\/MOP.0000000000000582","article-title":"Zika clinical updates: implications for pediatrics.","volume":"30","author":"Adachi","year":"2018","journal-title":"Curr Opin Pediatr"},{"issue":"20","key":"zoi180301r4","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1056\/NEJMsr1604338","article-title":"Zika virus and birth defects: reviewing the evidence for causality.","volume":"374","author":"Rasmussen","year":"2016","journal-title":"N Engl J Med"},{"issue":"8","key":"zoi180301r5","doi-asserted-by":"publisher","first-page":"1232","DOI":"10.3201\/eid1408.080287","article-title":"Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007.","volume":"14","author":"Lanciotti","year":"2008","journal-title":"Emerg Infect Dis"},{"key":"zoi180301r6","doi-asserted-by":"publisher","first-page":"227","DOI":"10.3389\/fneur.2018.00227","article-title":"Nervous system injury and neuroimaging of Zika virus infection.","volume":"9","author":"Wu","year":"2018","journal-title":"Front Neurol"},{"issue":"4","key":"zoi180301r7","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/S1473-3099(16)00125-0","article-title":"Zika virus and neurological disease: approaches to the unknown.","volume":"16","author":"Solomon","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"9062","key":"zoi180301r8","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1016\/S0140-6736(96)10182-3","article-title":"An early marker for neurological deficits after perinatal brain lesions.","volume":"349","author":"Prechtl","year":"1997","journal-title":"Lancet"},{"issue":"5","key":"zoi180301r10","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1111\/dmcn.12140","article-title":"A systematic review of tests to predict cerebral palsy in young children.","volume":"55","author":"Bosanquet","year":"2013","journal-title":"Dev Med Child Neurol"},{"issue":"9","key":"zoi180301r11","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1001\/jamapediatrics.2017.1689","article-title":"Early, accurate diagnosis and early intervention in cerebral palsy: advances in diagnosis and treatment.","volume":"171","author":"Novak","year":"2017","journal-title":"JAMA Pediatr"},{"issue":"64","key":"zoi180301r13","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1590\/1982-43272664201606","article-title":"Bayley-III scales of infant and toddler development: transcultural adaptation and psychometric properties.","volume":"26","author":"Madaschi","year":"2016","journal-title":"Paid\u00e9ia"},{"issue":"10","key":"zoi180301r14","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1111\/dmcn.2008.50.issue-10","article-title":"Content validity of the expanded and revised Gross Motor Function Classification System.","volume":"50","author":"Palisano","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"zoi180301r15","article-title":"General movements and motor outcomes in two infants exposed to Zika virus: brief report [published online February 16, 2018].","author":"Soares-Marangoni","journal-title":"Dev Neurorehabil"},{"issue":"3","key":"zoi180301r16","doi-asserted-by":"publisher","first-page":"e1978","DOI":"10.1002\/rmv.v28.3","article-title":"The neurological complications of chikungunya virus: a systematic review.","volume":"28","author":"Mehta","year":"2018","journal-title":"Rev Med Virol"},{"issue":"5","key":"zoi180301r17","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.ejpn.2008.09.004","article-title":"The predictive validity of general movements: a systematic review.","volume":"13","author":"Burger","year":"2009","journal-title":"Eur J Paediatr Neurol"},{"issue":"10","key":"zoi180301r18","doi-asserted-by":"publisher","first-page":"896","DOI":"10.1111\/dmcn.2011.53.issue-10","article-title":"Predictive validity of Prechtl\u2019s Method on the Qualitative Assessment of General Movements: a systematic review of the evidence.","volume":"53","author":"Darsaklis","year":"2011","journal-title":"Dev Med Child Neurol"},{"issue":"1","key":"zoi180301r19","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1111\/jpc.12995","article-title":"Sensitivity and specificity of General Movements Assessment for diagnostic accuracy of detecting cerebral palsy early in an Australian context.","volume":"52","author":"Morgan","year":"2016","journal-title":"J Paediatr Child Health"},{"issue":"1","key":"zoi180301r20","doi-asserted-by":"publisher","first-page":"26","DOI":"10.5858\/arpa.2016-0382-RA","article-title":"Zika virus infection in pregnancy, microcephaly, and maternal and fetal health: what we think, what we know, and what we think we know.","volume":"141","author":"Alvarado","year":"2017","journal-title":"Arch Pathol Lab Med"},{"issue":"10047","key":"zoi180301r21","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1016\/S0140-6736(16)30902-3","article-title":"Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation.","volume":"388","author":"Fran\u00e7a","year":"2016","journal-title":"Lancet"},{"issue":"47","key":"zoi180301r22","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.15585\/mmwr.mm6547e2","article-title":"Description of 13 infants born during October 2015\u2013January 2016 with congenital Zika virus infection without microcephaly at birth: Brazil.","volume":"65","author":"van der Linden","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"zoi180301r23","article-title":"Congenital Zika infection: neurology can occur without microcephaly [published online June 1, 2018].","author":"Cardoso","journal-title":"Arch Dis Child"},{"key":"zoi180301r24","doi-asserted-by":"publisher","first-page":"406","DOI":"10.3389\/fpsyg.2016.00406","article-title":"The General Movements Assessment helps us to identify preterm infants at risk for cognitive dysfunction.","volume":"7","author":"Einspieler","year":"2016","journal-title":"Front Psychol"},{"issue":"3","key":"zoi180301r25","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1080\/01942638.2017.1395380","article-title":"Feasibility of using General Movements Assessment of infants in the United States.","volume":"38","author":"Ricci","year":"2018","journal-title":"Phys Occup Ther Pediatr"},{"key":"zoi180301r26","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.earlhumdev.2018.02.001","article-title":"Prediction of neurodevelopment at one year of age using the General Movements Assessment in the neonatal surgical population.","volume":"118","author":"Crowle","year":"2018","journal-title":"Early Hum Dev"},{"key":"zoi180301r27","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.earlhumdev.2016.03.010","article-title":"Very low birth weight infants in China: the predictive value of the motor repertoire at 3 to 5 months for the motor performance at 12 months.","volume":"100","author":"Zang","year":"2016","journal-title":"Early Hum Dev"},{"issue":"6","key":"zoi180301r28","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1016\/j.ejpn.2016.07.019","article-title":"Early motor repertoire in very low birth weight infants in India is associated with motor development at one year.","volume":"20","author":"Adde","year":"2016","journal-title":"Eur J Paediatr Neurol"},{"issue":"8","key":"zoi180301r29","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.earlhumdev.2015.05.007","article-title":"General movements as a predictive tool of the neurological outcome in term born infants with hypoxic ischemic encephalopathy.","volume":"91","author":"Soleimani","year":"2015","journal-title":"Early Hum Dev"},{"issue":"4","key":"zoi180301r30","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.earlhumdev.2013.02.004","article-title":"Intra-uterine exposure to maternal opiate abuse and HIV: the impact on the developing nervous system.","volume":"89","author":"Palchik","year":"2013","journal-title":"Early Hum Dev"},{"key":"zoi180301r9","volume-title":"Prechtl\u2019s Method on the Qualitative Assessment of General Movements in Preterm, Term and Young Infants","author":"Einspieler","year":"2004"},{"key":"zoi180301r12","volume-title":"Bayley Scales of Infant and Toddler Development","author":"Bayley","year":"2006","edition":"3rd ed"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2720922","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T12:28:14Z","timestamp":1549888094000},"score":1,"resource":{"primary":{"URL":"http:\/\/jamanetworkopen.jamanetwork.com\/article.aspx?doi=10.1001\/jamanetworkopen.2018.7235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,18]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1,4]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2018.7235","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.734886266.793559365","asserted-by":"object"}]},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,18]]}}}