{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:52:12Z","timestamp":1790077932818,"version":"4.0.1"},"reference-count":30,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2020.14205","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T15:32:24Z","timestamp":1598542344000},"page":"e2014205","source":"Crossref","is-referenced-by-count":32,"title":["Effect of a Daily Text Messaging and Directly Supervised Therapy Intervention on Oral Mercaptopurine Adherence in Children With Acute Lymphoblastic Leukemia"],"prefix":"10.1001","volume":"3","author":[{"given":"Smita","family":"Bhatia","sequence":"first","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"Hageman","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Lennie","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Population Sciences, City of Hope, Duarte, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth L.","family":"McQuaid","sequence":"additional","affiliation":[{"name":"Department of Psychiatryand Human Behavior, Brown University, Providence, Rhode Island"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Duncan","sequence":"additional","affiliation":[{"name":"Department of Psychology,West Virginia University, Morgantown"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo","family":"Mascarenhas","sequence":"additional","affiliation":[{"name":"Cancer and Blood Disease Institute, Division of Hematology\/Oncology, Children\u2019s Hospital Los Angeles, Los Angeles, California"},{"name":"Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Freyer","sequence":"additional","affiliation":[{"name":"Cancer and Blood Disease Institute, Division of Hematology\/Oncology, Children\u2019s Hospital Los Angeles, Los Angeles, California"},{"name":"Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nkechi","family":"Mba","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology\/Oncology, Driscoll Children\u2019s Hospital, Corpus Christi, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Aristizabal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of California, San Diego, San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Walterhouse","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Hematology, Oncology, and Stem Cell Transplantation, Ann & Robert H Lurie Children\u2019s Hospital of Chicago, Chicago, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen","family":"Lew","sequence":"additional","affiliation":[{"name":"Aflac Cancer and Blood Disorders Center, Children\u2019s Healthcare of Atlanta, Emory University, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela Helen-Heilge","family":"Kempert","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology, Miller Children\u2019s and Women\u2019s Hospital, Long Beach, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Bennett","family":"Russell","sequence":"additional","affiliation":[{"name":"Wake Forest Baptist Comprehensive Cancer Center, Wake Forest University Health Sciences, Winston-Salem, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rene Y.","family":"McNall-Knapp","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shana","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Oncology, Children\u2019s National Medical Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ha","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Raetz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, NYU Langone Medical Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary V.","family":"Relling","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, St Jude Children\u2019s Research Hospital, Memphis, Tennessee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Landier","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"issue":"16","key":"zoi200542r1","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1056\/NEJMra1400972","article-title":"Acute lymphoblastic leukemia in children.","volume":"373","author":"Hunger","year":"2015","journal-title":"N Engl J Med"},{"key":"zoi200542r2","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1182\/asheducation.V2012.1.129.3800156","article-title":"Where do we stand in the treatment of relapsed acute lymphoblastic leukemia?","volume":"2012","author":"Raetz","year":"2012","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"4","key":"zoi200542r3","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/S1470-2045(17)30154-7","article-title":"DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial.","volume":"18","author":"Nielsen","year":"2017","journal-title":"Lancet Oncol"},{"issue":"1","key":"zoi200542r4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1056\/NEJM199007053230104","article-title":"Systemic exposure to mercaptopurine as a prognostic factor in acute lymphocytic leukemia in children.","volume":"323","author":"Koren","year":"1990","journal-title":"N Engl J Med"},{"issue":"9","key":"zoi200542r5","doi-asserted-by":"publisher","first-page":"2817","DOI":"10.1182\/blood.V93.9.2817","article-title":"Prognostic importance of 6-mercaptopurine dose intensity in acute lymphoblastic leukemia.","volume":"93","author":"Relling","year":"1999","journal-title":"Blood"},{"issue":"3","key":"zoi200542r6","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1001\/jamaoncol.2015.0245","article-title":"Systemic exposure to thiopurines and risk of relapse in children with acute lymphoblastic leukemia: a Children\u2019s Oncology Group study.","volume":"1","author":"Bhatia","year":"2015","journal-title":"JAMA Oncol"},{"issue":"1","key":"zoi200542r7","doi-asserted-by":"publisher","first-page":"30","DOI":"10.7326\/M18-0543","article-title":"ESPACOMP Medication Adherence Reporting Guideline (EMERGE).","volume":"169","author":"De Geest","year":"2018","journal-title":"Ann Intern Med"},{"issue":"5","key":"zoi200542r8","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/bcp.2012.73.issue-5","article-title":"A new taxonomy for describing and defining adherence to medications.","volume":"73","author":"Vrijens","year":"2012","journal-title":"Br J Clin Pharmacol"},{"issue":"15","key":"zoi200542r9","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1182\/blood-2014-01-552166","article-title":"6MP adherence in a multiracial cohort of children with acute lymphoblastic leukemia: a Children\u2019s Oncology Group study.","volume":"124","author":"Bhatia","year":"2014","journal-title":"Blood"},{"issue":"17","key":"zoi200542r10","doi-asserted-by":"publisher","first-page":"2094","DOI":"10.1200\/JCO.2011.38.9924","article-title":"Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children\u2019s oncology group.","volume":"30","author":"Bhatia","year":"2012","journal-title":"J Clin Oncol"},{"issue":"4","key":"zoi200542r11","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1177\/1043454211409582","article-title":"A grounded theory of the process of adherence to oral chemotherapy in Hispanic and Caucasian children and adolescents with acute lymphoblastic leukemia.","volume":"28","author":"Landier","year":"2011","journal-title":"J Pediatr Oncol Nurs"},{"issue":"11","key":"zoi200542r12","doi-asserted-by":"publisher","first-page":"726","DOI":"10.7326\/0003-4819-152-11-201006010-00232","article-title":"CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials.","volume":"152","author":"Schulz","year":"2010","journal-title":"Ann Intern Med"},{"issue":"2","key":"zoi200542r13","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1177\/109019818801500203","article-title":"Social learning theory and the Health Belief Model.","volume":"15","author":"Rosenstock","year":"1988","journal-title":"Health Educ Q"},{"issue":"3","key":"zoi200542r14","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1177\/0962280206074463","article-title":"Multiple imputation of discrete and continuous data by fully conditional specification.","volume":"16","author":"van Buuren","year":"2007","journal-title":"Stat Methods Med Res"},{"issue":"11","key":"zoi200542r15","article-title":"Interventions for enhancing medication adherence.","author":"Nieuwlaat","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"zoi200542r16","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.pec.2009.01.006","article-title":"A multimedia patient education program on colorectal cancer screening increases knowledge and willingness to consider screening among Hispanic\/Latino patients.","volume":"76","author":"Makoul","year":"2009","journal-title":"Patient Educ Couns"},{"issue":"3","key":"zoi200542r17","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1542\/peds.111.3.503","article-title":"Internet-enabled interactive multimedia asthma education program: a randomized trial.","volume":"111","author":"Krishna","year":"2003","journal-title":"Pediatrics"},{"issue":"1","key":"zoi200542r18","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1136\/jamia.2001.0080062","article-title":"Review of computer-generated outpatient health behavior interventions: clinical encounters \u201cin absentia\u201d.","volume":"8","author":"Revere","year":"2001","journal-title":"J Am Med Inform Assoc"},{"issue":"3","key":"zoi200542r19","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1001\/jamainternmed.2015.7667","article-title":"Mobile telephone text messaging for medication adherence in chronic disease: a meta-analysis.","volume":"176","author":"Thakkar","year":"2016","journal-title":"JAMA Intern Med"},{"issue":"2","key":"zoi200542r20","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.rmed.2009.10.003","article-title":"A daily SMS reminder increases adherence to asthma treatment: a three-month follow-up study.","volume":"104","author":"Strandbygaard","year":"2010","journal-title":"Respir Med"},{"issue":"4","key":"zoi200542r21","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1080\/09540121.2016.1214674","article-title":"Meta-analysis on the effect of text message reminders for HIV-related compliance.","volume":"29","author":"Mayer","year":"2017","journal-title":"AIDS Care"},{"issue":"9","key":"zoi200542r22","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1016\/j.ijmedinf.2012.05.005","article-title":"SMS reminders improve adherence to oral medication in type 2 diabetes patients who are real time electronically monitored.","volume":"81","author":"Vervloet","year":"2012","journal-title":"Int J Med Inform"},{"issue":"1","key":"zoi200542r23","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1053\/j.ajkd.2017.12.012","article-title":"A randomized trial of a multicomponent intervention to promote medication adherence: the Teen Adherence in Kidney Transplant Effectiveness of Intervention Trial (TAKE-IT).","volume":"72","author":"Foster","year":"2018","journal-title":"Am J Kidney Dis"},{"issue":"17","key":"zoi200542r24","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1056\/NEJM199404283301702","article-title":"The effect of directly observed therapy on the rates of drug resistance and relapse in tuberculosis.","volume":"330","author":"Weis","year":"1994","journal-title":"N Engl J Med"},{"issue":"7","key":"zoi200542r25","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1093\/cid\/ciw566","article-title":"Executive Summary: Official American Thoracic Society\/Centers for Disease Control and Prevention\/Infectious Diseases Society of America Clinical Practice Guidelines: treatment of drug-susceptible tuberculosis.","volume":"63","author":"Nahid","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"11","key":"zoi200542r26","doi-asserted-by":"publisher","first-page":"e449","DOI":"10.1016\/j.clml.2018.06.026","article-title":"Effect of adherence-enhancing interventions on adherence to tyrosine kinase inhibitor treatment in chronic myeloid leukemia (TAKE-IT): a quasi-experimental pre-post intervention multicenter pilot study.","volume":"18","author":"Leader","year":"2018","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"zoi200542r27","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.jclinepi.2017.07.011","article-title":"Congruence between patient characteristics and interventions may partly explain medication adherence intervention effectiveness: an analysis of 190 randomized controlled trials from a Cochrane systematic review.","volume":"91","author":"Allemann","year":"2017","journal-title":"J Clin Epidemiol"},{"issue":"14","key":"zoi200542r28","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1182\/blood-2016-07-726893","article-title":"Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: a Children\u2019s Oncology Group study.","volume":"129","author":"Landier","year":"2017","journal-title":"Blood"},{"issue":"15","key":"zoi200542r29","doi-asserted-by":"publisher","first-page":"10530","DOI":"10.1200\/JCO.2020.38.15_suppl.10530","article-title":"Individual prediction of non-adherence to oral mercaptopurine (6MP) in children with acute lymphoblastic leukemia (ALL): results from COG AALL03N1 study.","volume":"38","author":"Hoppmann","year":"2020","journal-title":"J Clin Oncol"},{"issue":"2","key":"zoi200542r30","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/01.qai.0000246034.86135.89","article-title":"Use of electronic monitoring induces a 40-day intervention effect in HIV patients.","volume":"43","author":"Deschamps","year":"2006","journal-title":"J Acquir Immune Defic Syndr"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2769841\/bhatia_2020_oi_200542_1602698697.64465.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T18:38:21Z","timestamp":1602700701000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2769841"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2020,8,27]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8,3]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.14205","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,27]]}}}