{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T09:43:23Z","timestamp":1789897403593,"version":"4.0.1"},"reference-count":60,"publisher":"American Medical Association (AMA)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2020.19046","type":"journal-article","created":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T15:01:04Z","timestamp":1601910064000},"page":"e2019046","source":"Crossref","is-referenced-by-count":20,"title":["Associations of Cord Blood Vitamin D and Preeclampsia With Offspring Blood Pressure in Childhood and Adolescence"],"prefix":"10.1001","volume":"3","author":[{"given":"Mingyu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin D.","family":"Michos","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland"},{"name":"Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoying","family":"Wang","sequence":"additional","affiliation":[{"name":"Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Wang","sequence":"additional","affiliation":[{"name":"Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Division of General Pediatrics & Adolescent Medicine, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel T.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland"},{"name":"Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"issue":"9741","key":"zoi200674r1","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/S0140-6736(10)60279-6","article-title":"Pre-eclampsia.","volume":"376","author":"Steegers","year":"2010","journal-title":"Lancet"},{"issue":"5","key":"zoi200674r2","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/ajh.2008.20","article-title":"Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004.","volume":"21","author":"Wallis","year":"2008","journal-title":"Am J Hypertens"},{"issue":"2","key":"zoi200674r3","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1161\/HYPERTENSIONAHA.111.00831","article-title":"Childhood blood pressure trends and risk factors for high blood pressure: the NHANES experience 1988-2008.","volume":"62","author":"Rosner","year":"2013","journal-title":"Hypertension"},{"issue":"25","key":"zoi200674r4","doi-asserted-by":"publisher","first-page":"3171","DOI":"10.1161\/CIRCULATIONAHA.107.730366","article-title":"Tracking of blood pressure from childhood to adulthood: a systematic review and meta-regression analysis.","volume":"117","author":"Chen","year":"2008","journal-title":"Circulation"},{"issue":"4","key":"zoi200674r5","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1161\/HYPERTENSIONAHA.119.14168","article-title":"Elevated Blood Pressure in Childhood or Adolescence and Cardiovascular Outcomes in Adulthood: A Systematic Review.","volume":"75","author":"Yang","year":"2020","journal-title":"Hypertension"},{"issue":"6","key":"zoi200674r6","doi-asserted-by":"publisher","first-page":"e1552","DOI":"10.1542\/peds.2011-3093","article-title":"Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic review.","volume":"129","author":"Davis","year":"2012","journal-title":"Pediatrics"},{"issue":"3","key":"zoi200674r7","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1203\/PDR.0b013e318193edf1","article-title":"Neonates born to mothers with preeclampsia exhibit sex-specific alterations in microvascular function.","volume":"65","author":"Stark","year":"2009","journal-title":"Pediatr Res"},{"issue":"2","key":"zoi200674r8","first-page":"632","article-title":"Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis.","volume":"46","author":"Schalekamp-Timmermans","year":"2017","journal-title":"Int J Epidemiol"},{"issue":"1","key":"zoi200674r9","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1097\/MCO.0b013e3282f2f4dd","article-title":"Vitamin D and cardiovascular disease risk.","volume":"11","author":"Michos","year":"2008","journal-title":"Curr Opin Clin Nutr Metab Care"},{"issue":"6","key":"zoi200674r10","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1016\/j.clnu.2019.08.015","article-title":"Vitamin D supplementation and incident preeclampsia: A systematic review and meta-analysis of randomized clinical trials.","volume":"39","author":"Fogacci","year":"2020","journal-title":"Clin Nutr"},{"key":"zoi200674r11","doi-asserted-by":"publisher","first-page":"500","DOI":"10.3389\/fendo.2018.00500","article-title":"The Implications of Vitamin D Status During Pregnancy on Mother and her Developing Child.","volume":"9","author":"Wagner","year":"2018","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"zoi200674r12","doi-asserted-by":"crossref","DOI":"10.1161\/HYPERTENSIONAHA.119.13120","article-title":"Vitamin D Trajectories From Birth to Early Childhood and Elevated Systolic Blood Pressure During Childhood and Adolescence.","volume":"74","author":"Wang","year":"2019","journal-title":"Hypertension"},{"issue":"9","key":"zoi200674r13","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.011485","article-title":"Cord Blood Vitamin D Levels and Early Childhood Blood Pressure: The Healthy Start Study.","volume":"8","author":"Sauder","year":"2019","journal-title":"J Am Heart Assoc"},{"issue":"12","key":"zoi200674r14","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1530\/EC-18-0308","article-title":"Blood pressure in 3-year-old girls associates inversely with umbilical cord serum 25-hydroxyvitamin D: an Odense Child Cohort study.","volume":"7","author":"Larsen","year":"2018","journal-title":"Endocr Connect"},{"issue":"6","key":"zoi200674r15","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1001\/jama.2014.1","article-title":"Preterm birth and random plasma insulin levels at birth and in early childhood.","volume":"311","author":"Wang","year":"2014","journal-title":"JAMA"},{"issue":"1","key":"zoi200674r16","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/S0020-7292(02)80002-9","article-title":"ACOG practice bulletin. Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002.","volume":"77","author":"ACOG Committee on Obstetric Practice","year":"2002","journal-title":"Int J Gynaecol Obstet"},{"issue":"1","key":"zoi200674r17","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1161\/HYPERTENSIONAHA.117.10944","article-title":"Maternal Exposure to Ambient Particulate Matter =2.5 \u00b5m During Pregnancy and the Risk for High Blood Pressure in Childhood.","volume":"72","author":"Zhang","year":"2018","journal-title":"Hypertension"},{"issue":"3","key":"zoi200674r18","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-1904","article-title":"Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents.","volume":"140","author":"Flynn","year":"2017","journal-title":"Pediatrics"},{"issue":"6","key":"zoi200674r19","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1309\/J32UF7GTQPWN25AP","article-title":"Quantification of serum 25-hydroxyvitamin D(2) and D(3) using HPLC-tandem mass spectrometry and examination of reference intervals for diagnosis of vitamin D deficiency.","volume":"125","author":"Saenger","year":"2006","journal-title":"Am J Clin Pathol"},{"issue":"3","key":"zoi200674r21","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1038\/pr.2013.110","article-title":"Longitudinal trajectory of vitamin D status from birth to early childhood in the development of food sensitization.","volume":"74","author":"Liu","year":"2013","journal-title":"Pediatr Res"},{"issue":"11","key":"zoi200674r22","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1111\/all.2011.66.issue-11","article-title":"Gene-vitamin D interactions on food sensitization: a prospective birth cohort study.","volume":"66","author":"Liu","year":"2011","journal-title":"Allergy"},{"issue":"1","key":"zoi200674r23","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1210\/jc.2010-2704","article-title":"The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know.","volume":"96","author":"Ross","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"zoi200674r24","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1214\/12-AOS1058","article-title":"On the definition of a confounder.","volume":"41","author":"VanderWeele","year":"2013","journal-title":"Ann Stat"},{"issue":"12","key":"zoi200674r25","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1093\/aje\/kwr258","article-title":"Seasonal variation in 25-hydroxyvitamin D concentrations in the cardiovascular health study.","volume":"174","author":"Shoben","year":"2011","journal-title":"Am J Epidemiol"},{"issue":"4","key":"zoi200674r26","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/sim.4067","article-title":"Multiple imputation using chained equations: Issues and guidance for practice.","volume":"30","author":"White","year":"2011","journal-title":"Stat Med"},{"issue":"1","key":"zoi200674r27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/EDE.0000000000000409","article-title":"Selection Bias Due to Loss to Follow Up in Cohort Studies.","volume":"27","author":"Howe","year":"2016","journal-title":"Epidemiology"},{"issue":"4 Pt 2","key":"zoi200674r28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1161\/01.HYP.2.4.130","article-title":"Prepregnant blood pressure, hypertension during pregnancy, and later blood pressure of mothers and offspring.","volume":"2","author":"Langford","year":"1980","journal-title":"Hypertension"},{"issue":"4","key":"zoi200674r29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0378-3782(89)90061-3","article-title":"Blood pressure and growth at 6 years of age among offsprings of mothers with hypertension of pregnancy.","volume":"19","author":"Palti","year":"1989","journal-title":"Early Hum Dev"},{"issue":"10","key":"zoi200674r30","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/j.1471-0528.1991.tb15339.x","article-title":"Pre-eclampsia and offspring\u2019s blood pressure, cognitive ability and physical development at 17-years-of-age.","volume":"98","author":"Seidman","year":"1991","journal-title":"Br J Obstet Gynaecol"},{"issue":"3","key":"zoi200674r31","first-page":"529","article-title":"Intrauterine exposure to preeclampsia and adolescent blood pressure, body size, and age at menarche in female offspring.","volume":"101","author":"Vatten","year":"2003","journal-title":"Obstet Gynecol"},{"issue":"3","key":"zoi200674r32","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1210\/jc.2002-020903","article-title":"Blood pressure, serum lipids, fasting insulin, and adrenal hormones in 12-year-old children born with maternal preeclampsia.","volume":"88","author":"Tenhola","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"issue":"2","key":"zoi200674r33","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1203\/01.pdr.0000196734.54473.e3","article-title":"Maternal preeclampsia predicts elevated blood pressure in 12-year-old children: evaluation by ambulatory blood pressure monitoring.","volume":"59","author":"Tenhola","year":"2006","journal-title":"Pediatr Res"},{"issue":"12","key":"zoi200674r34","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1161\/CIRCULATIONAHA.110.936674","article-title":"Preeclampsia and gestational hypertension are associated with childhood blood pressure independently of family adiposity measures: the Avon Longitudinal Study of Parents and Children.","volume":"122","author":"Geelhoed","year":"2010","journal-title":"Circulation"},{"issue":"3","key":"zoi200674r35","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/eurheartj\/ehr300","article-title":"Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children.","volume":"33","author":"Lawlor","year":"2012","journal-title":"Eur Heart J"},{"issue":"3","key":"zoi200674r36","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1161\/HYPERTENSIONAHA.113.01513","article-title":"Hypertensive disorders of pregnancy and cardiometabolic health in adolescent offspring.","volume":"62","author":"Fraser","year":"2013","journal-title":"Hypertension"},{"issue":"1","key":"zoi200674r37","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1161\/HYPERTENSIONAHA.111.172387","article-title":"Endothelial function and circulating biomarkers are disturbed in women and children after preeclampsia.","volume":"58","author":"Kvehaugen","year":"2011","journal-title":"Hypertension"},{"issue":"4","key":"zoi200674r38","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/jp.2011.88","article-title":"Prenatal and perinatal predictors of blood pressure at school age in former preterm, low birth weight infants.","volume":"32","author":"Belfort","year":"2012","journal-title":"J Perinatol"},{"issue":"1","key":"zoi200674r39","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s10654-013-9763-5","article-title":"Offspring\u2019s blood pressure and metabolic phenotype after exposure to gestational hypertension in utero.","volume":"28","author":"Miettola","year":"2013","journal-title":"Eur J Epidemiol"},{"issue":"5","key":"zoi200674r40","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.114.001422","article-title":"Associations of blood pressure in pregnancy with offspring blood pressure trajectories during childhood and adolescence: findings from a prospective study.","volume":"4","author":"Staley","year":"2015","journal-title":"J Am Heart Assoc"},{"issue":"10","key":"zoi200674r41","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1097\/HJH.0b013e328330052a","article-title":"Blood pressure in early adolescence in the offspring of preeclamptic and normotensive pregnancies.","volume":"27","author":"\u00d8glaend","year":"2009","journal-title":"J Hypertens"},{"issue":"3","key":"zoi200674r42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1001\/jamacardio.2019.5306","article-title":"Sex Differences in Blood Pressure Trajectories Over the Life Course.","volume":"5","author":"Ji","year":"2020","journal-title":"JAMA Cardiol"},{"issue":"7","key":"zoi200674r43","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1161\/CIRCULATIONAHA.119.043731","article-title":"Sex Differences in Primary and Secondary Prevention of Cardiovascular Disease in China.","volume":"141","author":"Xia","year":"2020","journal-title":"Circulation"},{"issue":"2","key":"zoi200674r44","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1002\/cphy.c140036","article-title":"Fetal programming and cardiovascular pathology.","volume":"5","author":"Alexander","year":"2015","journal-title":"Compr Physiol"},{"issue":"2","key":"zoi200674r45","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1042\/CS20110627","article-title":"Pre-eclampsia and offspring cardiovascular health: mechanistic insights from experimental studies.","volume":"123","author":"Davis","year":"2012","journal-title":"Clin Sci (Lond)"},{"issue":"5","key":"zoi200674r46","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1161\/CIRCULATIONAHA.110.941203","article-title":"Pulmonary and systemic vascular dysfunction in young offspring of mothers with preeclampsia.","volume":"122","author":"Jayet","year":"2010","journal-title":"Circulation"},{"issue":"2","key":"zoi200674r47","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1161\/HYPERTENSIONAHA.117.10688","article-title":"Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1.","volume":"72","author":"Gray","year":"2018","journal-title":"Hypertension"},{"issue":"4","key":"zoi200674r48","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.bpobgyn.2011.02.007","article-title":"The genetics of pre-eclampsia and other hypertensive disorders of pregnancy.","volume":"25","author":"Williams","year":"2011","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"2","key":"zoi200674r49","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1161\/CIRCRESAHA.113.301241","article-title":"Vitamin D and cardiovascular disease.","volume":"114","author":"Norman","year":"2014","journal-title":"Circ Res"},{"issue":"1","key":"zoi200674r50","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.jacc.2017.05.031","article-title":"Vitamin D and Cardiovascular Disease: Controversy Unresolved.","volume":"70","author":"Al Mheid","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"4 Pt 2","key":"zoi200674r51","first-page":"H1751","article-title":"1,25-Dihydroxyvitamin D3 regulation of cardiac myocyte proliferation and hypertrophy.","volume":"272","author":"O\u2019Connell","year":"1997","journal-title":"Am J Physiol"},{"issue":"2","key":"zoi200674r52","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1172\/JCI0215219","article-title":"1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system.","volume":"110","author":"Li","year":"2002","journal-title":"J Clin Invest"},{"key":"zoi200674r53","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3389\/fphys.2016.00043","article-title":"Role of the Placental Vitamin D Receptor in Modulating Feto-Placental Growth in Fetal Growth Restriction and Preeclampsia-Affected Pregnancies.","volume":"7","author":"Murthi","year":"2016","journal-title":"Front Physiol"},{"issue":"9","key":"zoi200674r54","doi-asserted-by":"crossref","first-page":"3517","DOI":"10.1210\/jc.2007-0718","article-title":"Maternal vitamin D deficiency increases the risk of preeclampsia.","volume":"92","author":"Bodnar","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"zoi200674r55","doi-asserted-by":"crossref","first-page":"c2289","DOI":"10.1136\/bmj.c2289","article-title":"Random measurement error and regression dilution bias.","volume":"340","author":"Hutcheon","year":"2010","journal-title":"BMJ"},{"issue":"5","key":"zoi200674r56","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/ajcn\/87.5.1107","article-title":"Does social class predict diet quality?","volume":"87","author":"Darmon","year":"2008","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"zoi200674r57","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3390\/ijerph16020281","article-title":"Effects of Socioeconomic Status on Physical and Psychological Health: Lifestyle as a Mediator.","volume":"16","author":"Wang","year":"2019","journal-title":"Int J Environ Res Public Health"},{"issue":"8","key":"zoi200674r58","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/OGX.0b013e3182331028","article-title":"A critical review of early-onset and late-onset preeclampsia.","volume":"66","author":"Raymond","year":"2011","journal-title":"Obstet Gynecol Surv"},{"issue":"16","key":"zoi200674r59","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.012436","article-title":"Trace Minerals, Heavy Metals, and Preeclampsia: Findings from the Boston Birth Cohort.","volume":"8","author":"Liu","year":"2019","journal-title":"J Am Heart Assoc"},{"issue":"6","key":"zoi200674r60","first-page":"950","article-title":"Preeclampsia and fetal growth.","volume":"96","author":"Odeg\u00e5rd","year":"2000","journal-title":"Obstet Gynecol"},{"key":"zoi200674r20","volume-title":"Reports funded by National Institutes of Health. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. National Academies Press","author":"Institute of Medicine Standing Committee on the Scientific Evaluation of Dietary Reference I. The National Academies Collection","year":"1997"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2771221\/zhang_2020_oi_200674_1601054767.9473.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T15:01:55Z","timestamp":1601910115000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2771221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,5]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,10,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.19046","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,5]]}}}