{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T09:30:03Z","timestamp":1771579803429,"version":"3.50.1"},"reference-count":36,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2021.14712","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T15:01:06Z","timestamp":1626102066000},"page":"e2114712","source":"Crossref","is-referenced-by-count":25,"title":["Prevalence of Headache Days and Disability 3 Years After Participation in the Childhood and Adolescent Migraine Prevention Medication Trial"],"prefix":"10.1001","volume":"4","author":[{"given":"Scott W.","family":"Powers","sequence":"first","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"},{"name":"Cincinnati Children\u2019s Headache Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher S.","family":"Coffey","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Clinical Trials Statistical and Data Management Center, University of Iowa College of Public Health, Iowa City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leigh A.","family":"Chamberlin","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dixie J.","family":"Ecklund","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Clinical Trials Statistical and Data Management Center, University of Iowa College of Public Health, Iowa City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Klingner","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Clinical Trials Statistical and Data Management Center, University of Iowa College of Public Health, Iowa City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon W.","family":"Yankey","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Clinical Trials Statistical and Data Management Center, University of Iowa College of Public Health, Iowa City"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James L.","family":"Peugh","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie L.","family":"Korbee","sequence":"additional","affiliation":[{"name":"Academic Regulatory & Monitoring Services, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerry","family":"Simmons","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie M.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Office for Clinical and Translational Research, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marielle A.","family":"Kabbouche","sequence":"additional","affiliation":[{"name":"Cincinnati Children\u2019s Headache Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"},{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Kacperski","sequence":"additional","affiliation":[{"name":"Cincinnati Children\u2019s Headache Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"},{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda L.","family":"Porter","sequence":"additional","affiliation":[{"name":"National Institute of Neurological Disorders and Stroke, Bethesda, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brooke L.","family":"Reidy","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"},{"name":"Cincinnati Children\u2019s Headache Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew D.","family":"Hershey","sequence":"additional","affiliation":[{"name":"Cincinnati Children\u2019s Headache Center, Cincinnati, Ohio"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio"},{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"issue":"6957","key":"zoi210444r1","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1136\/bmj.309.6957.765","article-title":"Prevalence of headache and migraine in schoolchildren.","volume":"309","author":"Abu-Arefeh","year":"1994","journal-title":"BMJ"},{"issue":"10","key":"zoi210444r2","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1093\/oxfordjournals.aje.a116014","article-title":"Age- and sex-specific incidence rates of migraine with and without visual aura.","volume":"134","author":"Stewart","year":"1991","journal-title":"Am J Epidemiol"},{"issue":"1","key":"zoi210444r3","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1001\/jama.1992.03480010072027","article-title":"Prevalence of migraine headache in the United States: relation to age, income, race, and other sociodemographic factors.","volume":"267","author":"Stewart","year":"1992","journal-title":"JAMA"},{"issue":"4","key":"zoi210444r4","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1046\/j.1468-2982.1997.1704488.x","article-title":"A 40-year follow-up of school children with migraine.","volume":"17","author":"Bille","year":"1997","journal-title":"Cephalalgia"},{"issue":"11","key":"zoi210444r5","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1016\/S1474-4422(17)30299-5","article-title":"Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.","volume":"16","author":"GBD 2015 Neurological Disorders Collaborator Group","year":"2017","journal-title":"Lancet Neurol"},{"issue":"10100","key":"zoi210444r7","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.","volume":"390","author":"GBD 2016 Disease and Injury Incidence and Prevalence Collaborators","year":"2017","journal-title":"Lancet"},{"issue":"9","key":"zoi210444r8","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1111\/head.v60.9","article-title":"What will it take to move the needle for headache disorders: an advocacy perspective.","volume":"60","author":"Shapiro","year":"2020","journal-title":"Headache"},{"issue":"1","key":"zoi210444r9","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/s11916-019-0743-7","article-title":"Migraine: stigma in society.","volume":"23","author":"Parikh","year":"2019","journal-title":"Curr Pain Headache Rep"},{"issue":"1","key":"zoi210444r10","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s10194-018-0846-2","article-title":"Migraine is first cause of disability in under 50s: will health politicians now take notice?","volume":"19","author":"Steiner","year":"2018","journal-title":"J Headache Pain"},{"issue":"8","key":"zoi210444r11","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1111\/head.v59.8","article-title":"New guidelines: interpretation, application and the future.","volume":"59","author":"Hershey","year":"2019","journal-title":"Headache"},{"issue":"1","key":"zoi210444r12","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s10194-017-0776-4","article-title":"Is topiramate effective for migraine prevention in patients less than 18 years of age: a meta-analysis of randomized controlled trials.","volume":"18","author":"Le","year":"2017","journal-title":"J Headache Pain"},{"issue":"3","key":"zoi210444r13","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1001\/jamapediatrics.2013.508","article-title":"Pharmacologic treatment of pediatric headaches: a meta-analysis.","volume":"167","author":"El-Chammas","year":"2013","journal-title":"JAMA Pediatr"},{"issue":"2","key":"zoi210444r14","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1111\/head.13025","article-title":"The Childhood and Adolescent Migraine Prevention (CHAMP) study: \u201cWhat do we do now?\u201d.","volume":"57","author":"Powers","year":"2017","journal-title":"Headache"},{"issue":"11","key":"zoi210444r15","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1212\/WNL.0000000000008105","article-title":"Practice guideline update summary: Pharmacologic treatment for pediatric migraine prevention: report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Headache Society.","volume":"93","author":"Oskoui","year":"2019","journal-title":"Neurology"},{"issue":"2","key":"zoi210444r16","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1056\/NEJMoa1610384","article-title":"Trial of amitriptyline, topiramate, and placebo for pediatric migraine.","volume":"376","author":"Powers","year":"2017","journal-title":"N Engl J Med"},{"issue":"7","key":"zoi210444r17","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1046\/j.1526-4610.2000.00085.x","article-title":"Effectiveness of amitriptyline in the prophylactic management of childhood headaches.","volume":"40","author":"Hershey","year":"2000","journal-title":"Headache"},{"issue":"10","key":"zoi210444r18","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1111\/j.1526-4610.2005.00262.x","article-title":"Topiramate for migraine prevention in children: a randomized, double-blind, placebo-controlled trial.","volume":"45","author":"Winner","year":"2005","journal-title":"Headache"},{"issue":"7","key":"zoi210444r19","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1177\/0883073807304201","article-title":"Topiramate in the prophylaxis of pediatric migraine: a double-blind placebo-controlled trial.","volume":"22","author":"Lakshmi","year":"2007","journal-title":"J Child Neurol"},{"issue":"5","key":"zoi210444r20","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1111\/head.2013.53.issue-5","article-title":"Childhood and Adolescent Migraine Prevention (CHAMP) study: a double-blinded, placebo-controlled, comparative effectiveness study of amitriptyline, topiramate, and placebo in the prevention of childhood and adolescent migraine.","volume":"53","author":"Hershey","year":"2013","journal-title":"Headache"},{"issue":"5","key":"zoi210444r21","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1111\/head.2016.56.issue-5","article-title":"The Childhood and Adolescent Migraine Prevention (CHAMP) study: a report on baseline characteristics of participants.","volume":"56","author":"Powers","year":"2016","journal-title":"Headache"},{"issue":"9","key":"zoi210444r22","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1038\/s41582-018-0042-7","article-title":"Paediatric migraine: evidence-based management and future directions.","volume":"14","author":"Orr","year":"2018","journal-title":"Nat Rev Neurol"},{"issue":"10","key":"zoi210444r23","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1111\/hed.2005.45.issue-10","article-title":"Outcome of a multidisciplinary approach to pediatric migraine at 1, 2, and 5 years.","volume":"45","author":"Kabbouche","year":"2005","journal-title":"Headache"},{"issue":"24","key":"zoi210444r24","doi-asserted-by":"publisher","first-page":"2622","DOI":"10.1001\/jama.2013.282533","article-title":"Cognitive behavioral therapy plus amitriptyline for chronic migraine in children and adolescents: a randomized clinical trial.","volume":"310","author":"Powers","year":"2013","journal-title":"JAMA"},{"issue":"11","key":"zoi210444r25","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1212\/WNL.57.11.2034","article-title":"PedMIDAS: development of a questionnaire to assess disability of migraines in children.","volume":"57","author":"Hershey","year":"2001","journal-title":"Neurology"},{"issue":"10","key":"zoi210444r26","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1111\/j.1468-2982.2004.00757.x","article-title":"Development of a patient-based grading scale for PedMIDAS.","volume":"24","author":"Hershey","year":"2004","journal-title":"Cephalalgia"},{"issue":"1","key":"zoi210444r28","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing.","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc B"},{"issue":"1","key":"zoi210444r29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition.","volume":"38","year":"2018","journal-title":"Cephalalgia"},{"issue":"2","key":"zoi210444r30","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1097\/j.pain.0000000000000379","article-title":"Expectations predict chronic pain treatment outcomes.","volume":"157","author":"Cormier","year":"2016","journal-title":"Pain"},{"issue":"6","key":"zoi210444r32","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1111\/head.v60.6","article-title":"Alterations in brain function after cognitive behavioral therapy for migraine in children and adolescents.","volume":"60","author":"Nahman-Averbuch","year":"2020","journal-title":"Headache"},{"issue":"4","key":"zoi210444r33","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1016\/j.jpeds.2014.06.040","article-title":"Harnessing the placebo effect in pediatric migraine clinic.","volume":"165","author":"Faria","year":"2014","journal-title":"J Pediatr"},{"issue":"10","key":"zoi210444r34","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1111\/head.12605","article-title":"Cognitive-behavioral therapy: how medical providers can increase patient and family openness and access to evidence-based multimodal therapy for pediatric migraine.","volume":"55","author":"Ernst","year":"2015","journal-title":"Headache"},{"issue":"8","key":"zoi210444r35","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1007\/s11606-008-0591-3","article-title":"In-office discussions of migraine: results from the American Migraine Communication Study.","volume":"23","author":"Lipton","year":"2008","journal-title":"J Gen Intern Med"},{"issue":"3","key":"zoi210444r36","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1007\/s11916-008-0040-3","article-title":"Facilitating communication with patients for improved migraine outcomes.","volume":"12","author":"Buse","year":"2008","journal-title":"Curr Pain Headache Rep"},{"key":"zoi210444r27","volume-title":"Multilevel Analysis: An Introduction to Basic and Advanced Multilevel Modeling","author":"Snijders","year":"2012","edition":"2nd ed"},{"key":"zoi210444r31","volume-title":"Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research","author":"Institute of Medicine (US) Committee on Advancing Pain Research, Care, and Education","year":"2011"},{"key":"zoi210444r6","unstructured":"AMF. 2017. Accessed December 8, 2020. https:\/\/americanmigrainefoundation.org\/move-against-migraine\/"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2781911\/powers_2021_oi_210444_1625588209.16625.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T23:11:32Z","timestamp":1725405092000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2781911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,12]]},"references-count":36,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2021.14712","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,12]]}}}