{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:32:52Z","timestamp":1790371972841,"version":"4.1.0"},"reference-count":6,"publisher":"American Medical Association (AMA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.0448","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T11:33:22Z","timestamp":1646048002000},"page":"e220448","source":"Crossref","is-referenced-by-count":71,"title":["Outcomes Among Patients With or Without Obesity and With Cancer Following Treatment With Immune Checkpoint Blockade"],"prefix":"10.1001","volume":"5","author":[{"given":"Seong-Keun","family":"Yoo","sequence":"first","affiliation":[{"name":"Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Chowell","sequence":"additional","affiliation":[{"name":"The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Valero","sequence":"additional","affiliation":[{"name":"Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc G. T.","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy A.","family":"Chan","sequence":"additional","affiliation":[{"name":"Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"issue":"9","key":"zld220008r1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1007\/s11912-016-0539-4","article-title":"The obesity paradox in cancer: a review.","volume":"18","author":"Lennon","year":"2016","journal-title":"Curr Oncol Rep"},{"issue":"1","key":"zld220008r2","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/s41591-018-0221-5","article-title":"Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.","volume":"25","author":"Wang","year":"2019","journal-title":"Nat Med"},{"issue":"1","key":"zld220008r3","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1186\/s12967-020-02404-x","article-title":"Association between body mass index and survival outcomes for cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis.","volume":"18","author":"An","year":"2020","journal-title":"J Transl Med"},{"issue":"5","key":"zld220008r4","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1001\/jamaoncol.2020.7684","article-title":"Response rates to anti-pd-1 immunotherapy in microsatellite-stable solid tumors with 10 or more mutations per megabase.","volume":"7","author":"Valero","year":"2021","journal-title":"JAMA Oncol"},{"issue":"9","key":"zld220008r5","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1016\/j.annonc.2020.07.002","article-title":"The FDA approval of pembrolizumab for adult and pediatric patients with tumor mutational burden (TMB) =10: a decision centered on empowering patients and their physicians.","volume":"31","author":"Subbiah","year":"2020","journal-title":"Ann Oncol"},{"issue":"5","key":"zld220008r6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/jim-2018-000722","article-title":"Advanced body composition assessment: from body mass index to body composition profiling.","volume":"66","author":"Borga","year":"2018","journal-title":"J Investig Med"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2789456\/yoo_2022_ld_220008_1645202391.30249.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T11:33:25Z","timestamp":1646048005000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2789456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.0448","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]}}}