{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:58:59Z","timestamp":1789473539796,"version":"build-2803163510"},"reference-count":39,"publisher":"American Medical Association (AMA)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.11107","type":"journal-article","created":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T15:00:56Z","timestamp":1652194856000},"page":"e2211107","source":"Crossref","is-referenced-by-count":5,"title":["Association of a Community Population and Clinic Education Intervention Program With Guideline-Based Aspirin Use for Primary Prevention of Cardiovascular Disease"],"prefix":"10.1001","volume":"5","author":[{"given":"Russell V.","family":"Luepker","sequence":"first","affiliation":[{"name":"Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis"},{"name":"Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milton","family":"Eder","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Finnegan","sequence":"additional","affiliation":[{"name":"Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy R.","family":"Van\u2019t Hof","sequence":"additional","affiliation":[{"name":"Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niki","family":"Oldenburg","sequence":"additional","affiliation":[{"name":"Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Duval","sequence":"additional","affiliation":[{"name":"Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, Minneapolis"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,5,10]]},"reference":[{"issue":"9","key":"zoi220333r1","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics\u20142020 update: a report from the American Heart Association.","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"10","key":"zoi220333r2","doi-asserted-by":"publisher","first-page":"e177","DOI":"10.1016\/j.jacc.2019.03.010","article-title":"2019 ACC\/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines.","volume":"74","author":"Arnett","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"zoi220333r3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008366.pub3","article-title":"Community wide interventions for increasing physical activity.","volume":"1","author":"Baker","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"zoi220333r4","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.pcad.2017.01.002","article-title":"Community-based healthy living interventions.","volume":"59","author":"Berra","year":"2017","journal-title":"Prog Cardiovasc Dis"},{"issue":"2","key":"zoi220333r5","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.gheart.2016.04.010","article-title":"Background, principles, implementation, and general experiences of the North Karelia Project.","volume":"11","author":"Puska","year":"2016","journal-title":"Glob Heart"},{"issue":"11","key":"zoi220333r6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004704.pub4","article-title":"Mass media interventions for smoking cessation in adults.","volume":"11","author":"Bala","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"zoi220333r7","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.2105\/AJPH.84.9.1383","article-title":"Community education for cardiovascular disease prevention: risk factor changes in the Minnesota Heart Health Program.","volume":"84","author":"Luepker","year":"1994","journal-title":"Am J Public Health"},{"key":"zoi220333r8","doi-asserted-by":"publisher","first-page":"485","DOI":"10.2147\/VHRM","article-title":"How to support smoking cessation in primary care and the community: a systematic review of interventions for the prevention of cardiovascular diseases.","volume":"15","author":"Odorico","year":"2019","journal-title":"Vasc Health Risk Manag"},{"key":"zoi220333r9","doi-asserted-by":"publisher","DOI":"10.1177\/2055207619890480","article-title":"Multifactorial e- and mHealth interventions for cardiovascular disease primary prevention: protocol for a systematic review and meta-analysis of randomised controlled trials.","volume":"5","author":"Direito","year":"2019","journal-title":"Digit Health"},{"issue":"21","key":"zoi220333r10","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1161\/CIRCULATIONAHA.118.031906","article-title":"Harnessing digital media to promote health and research.","volume":"137","author":"Ranard","year":"2018","journal-title":"Circulation"},{"issue":"2","key":"zoi220333r11","doi-asserted-by":"publisher","first-page":"157","DOI":"10.7326\/0003-4819-136-2-200201150-00015","article-title":"Aspirin for the primary prevention of cardiovascular events: recommendation and rationale.","volume":"136","author":"US Preventive Services Task Force","year":"2002","journal-title":"Ann Intern Med"},{"issue":"6","key":"zoi220333r12","doi-asserted-by":"publisher","first-page":"396","DOI":"10.7326\/0003-4819-150-6-200903170-00008","article-title":"Aspirin for the prevention of cardiovascular disease: US Preventive Services Task Force recommendation statement.","volume":"150","author":"US Preventive Services Task Force","year":"2009","journal-title":"Ann Intern Med"},{"issue":"12","key":"zoi220333r13","doi-asserted-by":"publisher","first-page":"836","DOI":"10.7326\/M16-0577","article-title":"Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: US Preventive Services Task Force recommendation statement.","volume":"164","author":"Bibbins-Domingo","year":"2016","journal-title":"Ann Intern Med"},{"issue":"4","key":"zoi220333r14","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.amepre.2020.10.025","article-title":"Aspirin use and misuse for the primary prevention of cardiovascular diseases.","volume":"60","author":"Luepker","year":"2021","journal-title":"Am J Prev Med"},{"issue":"1","key":"zoi220333r15","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.amepre.2005.08.042","article-title":"Aspirin use among US adults: Behavioral Risk Factor Surveillance System.","volume":"30","author":"Ajani","year":"2006","journal-title":"Am J Prev Med"},{"issue":"5","key":"zoi220333r16","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.amepre.2014.11.005","article-title":"Aspirin use among adults in the US: results of a national survey.","volume":"48","author":"Williams","year":"2015","journal-title":"Am J Prev Med"},{"issue":"4","key":"zoi220333r17","doi-asserted-by":"publisher","first-page":"192","DOI":"10.3821\/1913-701X-143.4.192","article-title":"Patient self-medication with ASA 81 mg.","volume":"143","author":"Taylor","year":"2010","journal-title":"Can Pharm J"},{"issue":"2","key":"zoi220333r18","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.jacc.2014.10.035","article-title":"Frequency and practice-level variation in inappropriate aspirin use for the primary prevention of cardiovascular disease: insights from the National Cardiovascular Disease Registry\u2019s Practice Innovation and Clinical Excellence registry.","volume":"65","author":"Hira","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"16","key":"zoi220333r19","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/1471-2261-14-16","article-title":"Aspirin use and knowledge in the community: a population- and health facility\u2013based survey for measuring local health system performance.","volume":"14","author":"Roth","year":"2014","journal-title":"BMC Cardiovasc Disord"},{"issue":"5","key":"zoi220333r20","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.amepre.2007.01.010","article-title":"Aspirin use among adults aged 40 and older in the United States: results of a national survey.","volume":"32","author":"Pignone","year":"2007","journal-title":"Am J Prev Med"},{"key":"zoi220333r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.conctc.2021.100772","article-title":"A community-based group randomized trial to increase aspirin use for primary prevention of cardiovascular disease: study protocol and baseline results for the \u201cAsk About Aspirin\u201d initiative.","volume":"22","author":"Duval","year":"2021","journal-title":"Contemp Clin Trials Commun"},{"issue":"7","key":"zoi220333r22","doi-asserted-by":"publisher","DOI":"10.1037\/0003-066X.32.7.513","article-title":"Toward an experimental ecology of human development.","volume":"32","author":"Bronfenbrenner","year":"1977","journal-title":"Am Psychol"},{"key":"zoi220333r25","doi-asserted-by":"publisher","first-page":"41","DOI":"10.2147\/CLEP","article-title":"Estimation of cardiovascular risk from self-reported knowledge of risk factors: insights from the Minnesota Heart Survey.","volume":"12","author":"Duval","year":"2020","journal-title":"Clin Epidemiol"},{"issue":"3","key":"zoi220333r26","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1017\/cts.2019.421","article-title":"An observational study of a clinical guideline implementation project in primary care.","volume":"4","author":"Eder","year":"2019","journal-title":"J Clin Transl Sci"},{"issue":"4","key":"zoi220333r27","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1177\/1076029613486537","article-title":"Confirmation of reported aspirin use in community studies: utility of serum thromboxane B2 measurement.","volume":"20","author":"Zantek","year":"2014","journal-title":"Clin Appl Thromb Hemost"},{"issue":"6","key":"zoi220333r29","doi-asserted-by":"publisher","DOI":"10.2196\/18014","article-title":"Health gain, cost impacts, and cost-effectiveness of a mass media campaign to promote smartphone apps for physical activity: modeling study.","volume":"8","author":"Mizdrak","year":"2020","journal-title":"JMIR Mhealth Uhealth"},{"issue":"2","key":"zoi220333r30","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1007\/s12160-016-9846-0","article-title":"mHealth technologies to influence physical activity and sedentary behaviors: behavior change techniques, systematic review and meta-analysis of randomized controlled trials.","volume":"51","author":"Direito","year":"2017","journal-title":"Ann Behav Med"},{"issue":"10","key":"zoi220333r31","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006328","article-title":"Contemporary primary prevention aspirin use by cardiovascular disease risk: impact of US Preventive Services Task Force recommendations, 2007-2015: a serial, cross-sectional study.","volume":"6","author":"Van\u2019t Hof","year":"2017","journal-title":"J Am Heart Assoc"},{"issue":"10152","key":"zoi220333r32","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/S0140-6736(18)31924-X","article-title":"Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.","volume":"392","author":"Gaziano","year":"2018","journal-title":"Lancet"},{"issue":"16","key":"zoi220333r33","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1056\/NEJMoa1804988","article-title":"Effects of aspirin for primary prevention in persons with diabetes mellitus.","volume":"379","author":"Bowman","year":"2018","journal-title":"N Engl J Med"},{"issue":"16","key":"zoi220333r34","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1056\/NEJMoa1803955","article-title":"Effect of aspirin on all-cause mortality in the healthy elderly.","volume":"379","author":"McNeil","year":"2018","journal-title":"N Engl J Med"},{"issue":"16","key":"zoi220333r35","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1056\/NEJMoa1805819","article-title":"Effect of aspirin on cardiovascular events and bleeding in the healthy elderly.","volume":"379","author":"McNeil","year":"2018","journal-title":"N Engl J Med"},{"issue":"10186","key":"zoi220333r36","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.1016\/S0140-6736(19)30541-0","article-title":"The rise and fall of aspirin in the primary prevention of cardiovascular disease.","volume":"393","author":"Raber","year":"2019","journal-title":"Lancet"},{"issue":"10","key":"zoi220333r37","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1093\/tbm\/ibab065","article-title":"News coverage about aspirin as a countervailing force against low-dose aspirin campaign promotion.","volume":"11","author":"Southwell","year":"2021","journal-title":"Transl Behav Med"},{"key":"zoi220333r23","volume-title":"Principles of Community Engagement","author":"McCloskey","year":"2011","edition":"2nd ed"},{"key":"zoi220333r24","volume-title":"Mind in Society","author":"Vygotsky","year":"1978"},{"key":"zoi220333r38","first-page":"1","volume-title":"Wireless Substitution: Early Release of Estimates From the National Health Interview Survey, January-June 2020","author":"Blumberg","year":"2021"},{"key":"zoi220333r28","unstructured":"Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System. 2020. Accessed February 23, 2022. https:\/\/www.cdc.gov\/brfss\/index.html"},{"key":"zoi220333r39","unstructured":"Centers for Disease Control and Prevention. Behavioral Risk Factor Surveillance System: 2019 Summary Data Quality Report. July 16, 2020. Accessed April 11, 2022. https:\/\/www.cdc.gov\/brfss\/annual_data\/2019\/pdf\/2019-sdqr-508.pdf"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2792125\/luepker_2022_oi_220333_1651594535.78175.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,10]],"date-time":"2022-05-10T15:01:04Z","timestamp":1652194864000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2792125"}},"subtitle":["A Nonrandomized Controlled Trial"],"short-title":[],"issued":{"date-parts":[[2022,5,10]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,2]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.11107","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,10]]}}}