{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:01:34Z","timestamp":1793102494843,"version":"4.5.0"},"reference-count":32,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.23619","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T17:07:01Z","timestamp":1658855221000},"page":"e2223619","source":"Crossref","is-referenced-by-count":74,"title":["Prehospital Lyophilized Plasma Transfusion for Trauma-Induced Coagulopathy in Patients at Risk for Hemorrhagic Shock"],"prefix":"10.1001","volume":"5","author":[{"given":"Daniel","family":"Jost","sequence":"first","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Lemoine","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Lemoine","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9ment","family":"Derkenne","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Beaume","sequence":"additional","affiliation":[{"name":"Bataillon de Marins-Pompiers de Marseille, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Lano\u00eb","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Maurin","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Louis-Delauri\u00e8re","sequence":"additional","affiliation":[{"name":"Direction de la Formation, de la Recherche et de l\u2019Innovation, Service de Sant\u00e9 des Arm\u00e9es, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma\u00eblle","family":"Delacote","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Dang-Minh","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn","family":"Franchin-Frattini","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Bihannic","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Savary","sequence":"additional","affiliation":[{"name":"Emergency Department, Angers University Hospital, Angers, France"},{"name":"Research Institute for Environmental and Occupational Health\u2013Unit\u00e9 Mixte de Recherche (UMR)_S 1085, France Emergency Department, Angers University Hospital, Angers, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albrice","family":"Levrat","sequence":"additional","affiliation":[{"name":"Department of Intensive Care, Annecy Hospital, Annecy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mence","family":"Baudouin","sequence":"additional","affiliation":[{"name":"Service Mobile d\u2019Urgence et de R\u00e9animation de Paris, H\u00f4pital Lariboisi\u00e8re, Assistance Publique\u2013H\u00f4pitaux de Paris (AP-HP) and Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Trichereau","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Salom\u00e9","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Frattini","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivien Hong Tuan","family":"Ha","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Jouffroy","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"},{"name":"Intensive Care Unit, Ambroise Par\u00e9 Hospital, AP-HP and Paris Saclay University, Boulogne Billancourt, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Seguineau","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy","family":"Titreville","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Roquet","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"},{"name":"Service d\u2019Anesth\u00e9sie-R\u00e9animation, H\u00f4pital Europ\u00e9en Georges-Pompidou, AP-HP, Paris, France"},{"name":"Service de Biostatistique et Informatique M\u00e9dicale, Unit\u00e9 Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, UMR 1153, Universit\u00e9 Paris Diderot, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Stibbe","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Vivien","sequence":"additional","affiliation":[{"name":"Service d\u2019Aide M\u00e9dicale Urgente de Paris, H\u00f4pital Necker-Enfants Malades, AP-HP and Universit\u00e9 de Paris, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Verret","sequence":"additional","affiliation":[{"name":"Direction de la Formation, de la Recherche et de l\u2019Innovation, Service de Sant\u00e9 des Arm\u00e9es, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Bignand","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Travers","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Martinaud","sequence":"additional","affiliation":[{"name":"Department of Clinical Operations, French Military Blood Institute, Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Arock","sequence":"additional","affiliation":[{"name":"Laboratory of Hematology, Piti\u00e9-Salp\u00eatri\u00e8re Hospital, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Raux","sequence":"additional","affiliation":[{"name":"D\u00e9partement d\u2019Anesth\u00e9sie R\u00e9animation, AP-HP Groupe Hospitalier Universitaire, AP-HP\u2013Sorbonne Universit\u00e9, Site Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Prunet","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Ausset","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care, Percy Military Teaching Hospital, Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Sailliol","sequence":"additional","affiliation":[{"name":"Department of Clinical Operations, French Military Blood Institute, Clamart, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Tourtier","sequence":"additional","affiliation":[{"name":"Paris Fire Brigade Medical Emergency Department, Paris, France"},{"name":"Department of Anesthesiology and Intensive Care, B\u00e9gin Military Teaching Hospital, Saint-Mand\u00e9, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souha","family":"Albinni","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari\u00e9","family":"Attias","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Benchetritt","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Benichou","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Bihannic","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Boizat","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Boutinaud","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Calinet","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Camoin-Jau","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Cerro","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Cesareo","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noureddine","family":"Chahir","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Chassery","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Chollet","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anouk","family":"Choubard","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ga\u00eblle","family":"Clavere","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Clavier","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Courtade","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Creppy","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-St\u00e9phane","family":"David","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"De Raucourt","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Debord","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9e","family":"Delort","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Deruaz-Cunsolo","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Dettori","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Dhers","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Dias","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxime","family":"Diaz","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Dieuset","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Yves","family":"Dubien","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois-Xavier","family":"Duchateau","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Duranteau","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Fiot","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Flocard","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Foissaud","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Fournier","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Francois","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Gaget","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Garnier","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Gaste","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Grimault","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Yves","family":"Gueugniaud","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakia","family":"Idir","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Burnichon","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Journois","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Blanc-Jouvan","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Kerbaul","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Klein","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"Lafitte","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Langeron","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Lassale","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Lebouc","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lecarpentier","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Lejeune","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micka\u00ebl","family":"Lemaire","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Leniger","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Leone","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudie","family":"Leostic","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Lutomski","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Sailliol","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude-Denis","family":"Martin","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Matheron","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Mathieu","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Christine","family":"Mendes","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Mermillod-Blondin","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Neuschwander","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Oueidat","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Ould-Ahmed","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Ozier","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Paugam","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Peduzzi","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Petermann","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Peytel","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Picou-Leblanc","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Pinero","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Plaisance","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Raba","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Ricard","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Romanacce","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Rossignol","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Rougelin-Clapasson","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelie","family":"Saint-Paul","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Idri","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Scotto","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Senent","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Smadja","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Tazarourte","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Topin","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Trichet","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexia","family":"Vocel","sequence":"additional","affiliation":[{"name":"for the Prehospital Lyophilized Plasma (PREHO-PLYO) Study Group"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"issue":"1","key":"zoi220667r2","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.injury.2010.11.003","article-title":"Early coagulopathy in trauma patients: an on-scene and hospital admission study.","volume":"43","author":"Floccard","year":"2012","journal-title":"Injury"},{"issue":"1","key":"zoi220667r3","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/s41572-021-00264-3","article-title":"Trauma-induced coagulopathy.","volume":"7","author":"Moore","year":"2021","journal-title":"Nat Rev Dis Primers"},{"issue":"8","key":"zoi220667r4","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.135350","article-title":"Prehospital plasma is associated with distinct biomarker expression following injury.","volume":"5","author":"Gruen","year":"2020","journal-title":"JCI Insight"},{"issue":"1","key":"zoi220667r5","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1186\/s13054-019-2347-3","article-title":"The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition.","volume":"23","author":"Spahn","year":"2019","journal-title":"Crit Care"},{"issue":"3","key":"zoi220667r6","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1097\/TA.0000000000003012","article-title":"Freeze-dried plasma for major trauma\u2014systematic review and meta-analysis.","volume":"90","author":"Mok","year":"2021","journal-title":"J Trauma Acute Care Surg"},{"issue":"10144","key":"zoi220667r7","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/S0140-6736(18)31553-8","article-title":"Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial.","volume":"392","author":"Moore","year":"2018","journal-title":"Lancet"},{"issue":"4","key":"zoi220667r8","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1056\/NEJMoa1802345","article-title":"Prehospital plasma during air medical transport in trauma patients at risk for hemorrhagic shock.","volume":"379","author":"Sperry","year":"2018","journal-title":"N Engl J Med"},{"issue":"3","key":"zoi220667r9","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1111\/jth.2018.16.issue-3","article-title":"French lyophilized plasma versus fresh frozen plasma for the initial management of trauma-induced coagulopathy: a randomized open-label trial.","volume":"16","author":"Garrigue","year":"2018","journal-title":"J Thromb Haemost"},{"issue":"1","key":"zoi220667r10","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s13063-020-4049-1","article-title":"French lyophilized plasma versus normal saline for post-traumatic coagulopathy prevention and correction: PREHO-PLYO protocol for a multicenter randomized controlled clinical trial.","volume":"21","author":"Jost","year":"2020","journal-title":"Trials"},{"issue":"RR-1","key":"zoi220667r11","first-page":"1","article-title":"Guidelines for field triage of injured patients: recommendations of the National Expert Panel on Field Triage, 2011.","volume":"61","author":"Sasser","year":"2012","journal-title":"MMWR Recomm Rep"},{"issue":"6","key":"zoi220667r12","doi-asserted-by":"publisher","first-page":"1476","DOI":"10.1097\/TA.0000000000000239","article-title":"Evaluation of the performance of French physician-staffed emergency medical service in the triage of major trauma patients.","volume":"76","author":"Hamada","year":"2014","journal-title":"J Trauma Acute Care Surg"},{"issue":"6","key":"zoi220667r14","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.accpm.2018.10.013","article-title":"French legal approach to clinical research.","volume":"37","author":"Toulouse","year":"2018","journal-title":"Anaesth Crit Care Pain Med"},{"issue":"20","key":"zoi220667r15","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.","volume":"310","author":"World Medical Association","year":"2013","journal-title":"JAMA"},{"issue":"1","key":"zoi220667r16","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.resuscitation.2004.04.001","article-title":"International EMS systems: France.","volume":"63","author":"Adnet","year":"2004","journal-title":"Resuscitation"},{"issue":"6","key":"zoi220667r17","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1111\/trf.2004.44.issue-6","article-title":"Blood transfusion rates in the care of acute trauma.","volume":"44","author":"Como","year":"2004","journal-title":"Transfusion"},{"issue":"1","key":"zoi220667r18","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/s12893-018-0427-y","article-title":"Crystalloid resuscitation in trauma patients: deleterious effect of 5L or more in the first 24h.","volume":"18","author":"Jones","year":"2018","journal-title":"BMC Surg"},{"issue":"2","key":"zoi220667r19","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1097\/SLA.0000000000003324","article-title":"Prehospital blood product and crystalloid resuscitation in the severely injured patient: a secondary analysis of the prehospital air medical plasma trial.","volume":"273","author":"Guyette","year":"2021","journal-title":"Ann Surg"},{"issue":"6","key":"zoi220667r20","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1097\/TA.0b013e31822f1285","article-title":"Use of freeze-dried plasma in French intensive care unit in Afghanistan.","volume":"71","author":"Martinaud","year":"2011","journal-title":"J Trauma"},{"issue":"1","key":"zoi220667r21","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12874-017-0426-1","article-title":"Sample size calculations based on a difference in medians for positively skewed outcomes in health care studies.","volume":"17","author":"O\u2019Keeffe","year":"2017","journal-title":"BMC Med Res Methodol"},{"issue":"3","key":"zoi220667r22","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1080\/00223891.2018.1530680","article-title":"Rebutting existing misconceptions about multiple imputation as a method for handling missing data.","volume":"102","author":"van Ginkel","year":"2020","journal-title":"J Pers Assess"},{"issue":"5","key":"zoi220667r23","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1001\/jama.2015.12","article-title":"Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.","volume":"313","author":"Holcomb","year":"2015","journal-title":"JAMA"},{"issue":"9","key":"zoi220667r24","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1007\/s00134-019-05724-9","article-title":"Analysis of the medical response to November 2015 Paris terrorist attacks: resource utilization according to the cause of injury.","volume":"45","author":"Raux","year":"2019","journal-title":"Intensive Care Med"},{"issue":"5","key":"zoi220667r25","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1056\/NEJMra1510059","article-title":"Pragmatic trials.","volume":"375","author":"Ford","year":"2016","journal-title":"N Engl J Med"},{"issue":"1","key":"zoi220667r26","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1097\/TA.0000000000002485","article-title":"Prehospital plasma in injured patients is associated with survival principally in blunt injury: results from two randomized prehospital plasma trials.","volume":"88","author":"Reitz","year":"2020","journal-title":"J Trauma Acute Care Surg"},{"issue":"10","key":"zoi220667r27","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.16869","article-title":"Association of prehospital plasma with survival in patients with traumatic brain injury: a secondary analysis of the PAMPer cluster randomized clinical trial.","volume":"3","author":"Gruen","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"4","key":"zoi220667r28","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1097\/TA.0000000000001569","article-title":"Prehospital administration of freeze-dried plasma, is it the solution for trauma casualties?","volume":"83","author":"Shlaifer","year":"2017","journal-title":"J Trauma Acute Care Surg"},{"issue":"2","key":"zoi220667r29","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1097\/TA.0b013e3182095a0a","article-title":"Identifying risk for massive transfusion in the relatively normotensive patient: utility of the prehospital shock index.","volume":"70","author":"Vandromme","year":"2011","journal-title":"J Trauma"},{"issue":"10","key":"zoi220667r30","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1111\/jth.v17.10","article-title":"Trauma-targeted delivery of tranexamic acid improves hemostasis and survival in rat liver hemorrhage model.","volume":"17","author":"Girish","year":"2019","journal-title":"J Thromb Haemost"},{"issue":"2","key":"zoi220667r31","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1097\/SHK.0000000000001432","article-title":"Antithrombin III contributes to the protective effects of fresh frozen plasma following hemorrhagic shock by preventing syndecan-1 shedding and endothelial barrier disruption.","volume":"53","author":"Lopez","year":"2020","journal-title":"Shock"},{"issue":"1","key":"zoi220667r32","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1097\/TA.0000000000003173","article-title":"Lactate as a mediator of prehospital plasma mortality reduction in hemorrhagic shock.","volume":"91","author":"Canton","year":"2021","journal-title":"J Trauma Acute Care Surg"},{"key":"zoi220667r1","author":"Crowe","year":"2021"},{"key":"zoi220667r13","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/978-3-030-53606-0_15","volume-title":"Trauma Induced Coagulopathy","author":"Thorn","year":"2021"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2794640\/jost_2022_oi_220667_1658244621.02158.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T17:07:05Z","timestamp":1658855225000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2794640"}},"subtitle":["A Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2022,7,26]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.23619","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,26]]}}}