{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:37:29Z","timestamp":1783039049198,"version":"3.54.6"},"reference-count":15,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.24657","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T11:33:09Z","timestamp":1659439989000},"page":"e2224657","source":"Crossref","is-referenced-by-count":50,"title":["Association of Receiving a Fourth Dose of the BNT162b Vaccine With SARS-CoV-2 Infection Among Health Care Workers in Israel"],"prefix":"10.1001","volume":"5","author":[{"given":"Matan J.","family":"Cohen","sequence":"first","affiliation":[{"name":"Clalit Health Services, Jerusalem District, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonatan","family":"Oster","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allon E.","family":"Moses","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avishay","family":"Spitzer","sequence":"additional","affiliation":[{"name":"Department of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shmuel","family":"Benenson","sequence":"additional","affiliation":[{"name":"Unit for Infection Prevention and Control, Shaare-Zedek Medical Center, Jerusalem, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Israeli-Hospitals 4th Vaccine Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asala","family":"Abu-Ahmad","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoel","family":"Angel","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronen","family":"Ben-Ami","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debby","family":"Ben-David","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inon","family":"Buda","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Chowers","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayelet","family":"Elbirt","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khetam","family":"Hussein","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chezi","family":"Levi","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Maor","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Nir-Paz","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alona","family":"Paz","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Saiag","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomo","family":"Maayan","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Shachor-Meyouhas","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pnina","family":"Shitrit","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Weinberger","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonit","family":"Wiener-Well","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adi","family":"Zaidman Shimshovitz","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli","family":"Sprecher","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiba","family":"Zayyad","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oren","family":"Zimhony","sequence":"additional","affiliation":[{"name":"and the  Israeli-Hospitals 4th Vaccine Working Group"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"issue":"5","key":"zoi220691r2","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1056\/NEJMc2119358","article-title":"Third BNT162b2 vaccination neutralization of SARS-CoV-2 Omicron infection.","volume":"386","author":"Nemet","year":"2022","journal-title":"N Engl J Med"},{"issue":"2","key":"zoi220691r3","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1001\/jamainternmed.2021.7382","article-title":"Odds of testing positive for SARS-CoV-2 following receipt of 3 vs 2 doses of the BNT162b2 mRNA vaccine.","volume":"182","author":"Patalon","year":"2022","journal-title":"JAMA Intern Med"},{"issue":"15","key":"zoi220691r4","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1056\/NEJMoa2114255","article-title":"Protection of BNT162b2 vaccine booster against Covid-19 in Israel.","volume":"385","author":"Bar-On","year":"2021","journal-title":"N Engl J Med"},{"issue":"18","key":"zoi220691r5","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1056\/NEJMoa2201570","article-title":"Protection by a fourth dose of BNT162b2 against Omicron in Israel.","volume":"386","author":"Bar-On","year":"2022","journal-title":"N Engl J Med"},{"key":"zoi220691r6","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-022-01832-0","article-title":"Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60?years.","author":"Arbel","year":"2022","journal-title":"Nat Med"},{"issue":"5","key":"zoi220691r7","doi-asserted-by":"publisher","first-page":"735.e1","DOI":"10.1016\/j.cmi.2022.01.019","article-title":"The effect of a third BNT162b2 vaccine on breakthrough infections in health care workers: a cohort analysis.","volume":"28","author":"Oster","year":"2022","journal-title":"Clin Microbiol Infect"},{"issue":"14","key":"zoi220691r8","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1056\/NEJMc2202542","article-title":"Efficacy of a fourth dose of Covid-19 mRNA vaccine against Omicron.","volume":"386","author":"Regev-Yochay","year":"2022","journal-title":"N Engl J Med"},{"key":"zoi220691r9","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(22)00271-7","article-title":"Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial.","author":"Munro","year":"2022","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"zoi220691r10","doi-asserted-by":"publisher","first-page":"455","DOI":"10.7326\/L21-0598","article-title":"Antibody response to a fourth messenger RNA COVID-19 vaccine dose in kidney transplant recipients: a case series.","volume":"175","author":"Caillard","year":"2022","journal-title":"Ann Intern Med"},{"issue":"12","key":"zoi220691r11","doi-asserted-by":"publisher","first-page":"e280","DOI":"10.1097\/TP.0000000000003934","article-title":"Antibody response to a fourth dose of a SARS-CoV-2 vaccine in solid organ transplant recipients: a case series.","volume":"105","author":"Alejo","year":"2021","journal-title":"Transplantation"},{"issue":"2","key":"zoi220691r12","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(22)00010-8","article-title":"Fourth dose of COVID-19 vaccines in Israel.","volume":"10","author":"Burki","year":"2022","journal-title":"Lancet Respir Med"},{"issue":"2","key":"zoi220691r13","article-title":"Learning from the Italian experience during COVID-19 pandemic waves: be prepared and mind some crucial aspects.","volume":"92","author":"Deana","year":"2021","journal-title":"Acta Biomed"},{"key":"zoi220691r14","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.jhin.2020.11.020","article-title":"Intention to get vaccinations against COVID-19 in French healthcare workers during the first pandemic wave: a cross-sectional survey.","volume":"108","author":"Gagneux-Brunon","year":"2021","journal-title":"J Hosp Infect"},{"key":"zoi220691r15","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.jhin.2021.02.017","article-title":"Adherence of nurses to annual seasonal influenza vaccination over a 5-year period.","volume":"112","author":"Chan","year":"2021","journal-title":"J Hosp Infect"},{"key":"zoi220691r1","unstructured":"Data Gov. Israeli Ministry of Health COVID-19 data center [in Hebrew]. Accessed June 1, 2022. https:\/\/data.gov.il\/dataset\/covid-19"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2794864\/cohen_2022_oi_220691_1658779862.23463.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T11:33:13Z","timestamp":1659439993000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2794864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,2]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.24657","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.04.11.22273327","asserted-by":"object"}]},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,2]]}}}