{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:54:39Z","timestamp":1788846879597,"version":"build-2803163510"},"reference-count":42,"publisher":"American Medical Association (AMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.30518","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T11:32:42Z","timestamp":1662636762000},"page":"e2230518","source":"Crossref","is-referenced-by-count":38,"title":["Association of Blood-Based Brain Injury Biomarker Concentrations With Outcomes After Pediatric Cardiac Arrest"],"prefix":"10.1001","volume":"5","author":[{"given":"Ericka L.","family":"Fink","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Department of Pediatrics, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"Kochanek","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Department of Pediatrics, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok","family":"Panigrahy","sequence":"additional","affiliation":[{"name":"Department of Radiology, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue R.","family":"Beers","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel P.","family":"Berger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fclya","family":"Bayir","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Department of Pediatrics, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"},{"name":"Children\u2019s Neuroscience Institute, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Pineda","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Critical Care Medicine, Children\u2019s Hospital Los Angeles, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Newth","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Critical Care Medicine, Children\u2019s Hospital Los Angeles, Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis A.","family":"Topjian","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care Medicine, Children\u2019s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig A.","family":"Press","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neurology, Children\u2019s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline B.","family":"Maddux","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Hospital Colorado, University of Colorado School of Medicine, Aurora"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick","family":"Willyerd","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Phoenix Children\u2019s Hospital, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Hunt","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Children\u2019s Center, Baltimore, Maryland"},{"name":"Department of Pediatrics, Johns Hopkins Children\u2019s Center, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Siems","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Children\u2019s Center, Baltimore, Maryland"},{"name":"Department of Pediatrics, Johns Hopkins Children\u2019s Center, Baltimore, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa G.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Divisions of Pediatric Neurology and Critical Care Medicine, Nationwide Children\u2019s Hospital, Columbus, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lincoln","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Washington School of Medicine, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Wenger","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley","family":"Doughty","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Wesley","family":"Diddle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s National Hospital, District of Columbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Patregnani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Barbara Bush Children\u2019s Hospital, Portland, Maine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Piantino","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Oregon Health & Science University, Portland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen Hallermeier","family":"Walson","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Healthcare of Atlanta, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binod","family":"Balakrishnan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Wisconsin, Medical College of Wisconsin, Milwaukee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Wisconsin, Medical College of Wisconsin, Milwaukee"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Friess","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, St Louis Children\u2019s Hospital, St Louis, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Maloney","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Rubin","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara L.","family":"Haller","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amery","family":"Treble-Barna","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R. S. B.","family":"Clark","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Department of Pediatrics, UPMC Children\u2019s Hospital of Pittsburgh, Pittsburgh, Pennsylvania"},{"name":"Safar Center for Resuscitation Research, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Fabio","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Maloney","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela","family":"Rubin","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beena","family":"Desai","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen G.","family":"Richardson","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Bates","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darshana","family":"Parikh","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice","family":"Prodell","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddie","family":"Winters","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Smith","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeni","family":"Kwok","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Cabrales","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronke","family":"Adewale","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam","family":"Melvin","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadaf","family":"Shad","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Siegel","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Murkowski","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Kasch","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josey","family":"Hensley","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Steele","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Brown","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Burrows","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Hlivka","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deana","family":"Rich","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amila","family":"Tutundzic","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Day","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Barganier","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Wolfe","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mackenzie","family":"Little","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse","family":"Tomanio","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Patel","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Hession","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yamila","family":"Sierra","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rhonda","family":"Jones","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Benken","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Elmer","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subramanian","family":"Subramanian","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikala","family":"Narayanan","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Toney","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Wallace","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tami","family":"Robinson","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Frank","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Bluml","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Wisnowski","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keri","family":"Feldman","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Vemulapalli","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Ryan","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Szypulski","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Keys","sequence":"additional","affiliation":[{"name":"for the Personalizing Outcomes After Child Cardiac Arrest (POCCA) Investigators"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,9,8]]},"reference":[{"issue":"1","key":"zoi220867r1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1001\/jama.295.1.50","article-title":"First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults.","volume":"295","author":"Nadkarni","year":"2006","journal-title":"JAMA"},{"issue":"11","key":"zoi220867r2","doi-asserted-by":"publisher","first-page":"1484","DOI":"10.1161\/CIRCULATIONAHA.108.802678","article-title":"Epidemiology and outcomes from out-of-hospital cardiac arrest in children: the Resuscitation Outcomes Consortium Epistry\u2013Cardiac Arrest.","volume":"119","author":"Atkins","year":"2009","journal-title":"Circulation"},{"issue":"7","key":"zoi220867r3","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.1097\/CCM.0b013e3181a00a6a","article-title":"In-hospital versus out-of-hospital pediatric cardiac arrest: a multicenter cohort study.","volume":"37","author":"Moler","year":"2009","journal-title":"Crit Care Med"},{"issue":"9","key":"zoi220867r4","doi-asserted-by":"publisher","first-page":"e517","DOI":"10.1161\/CIR.0000000000000702","article-title":"Standards for studies of neurological prognostication in comatose survivors of cardiac arrest: a scientific statement from the American Heart Association.","volume":"140","author":"Geocadin","year":"2019","journal-title":"Circulation"},{"issue":"3","key":"zoi220867r5","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1097\/01.ccm.0000435668.53188.80","article-title":"Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest.","volume":"42","author":"Fink","year":"2014","journal-title":"Crit Care Med"},{"issue":"4","key":"zoi220867r6","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/PCC.0b013e318198bdb5","article-title":"Neuron-specific enolase and S-100B are associated with neurologic outcome after pediatric cardiac arrest.","volume":"10","author":"Topjian","year":"2009","journal-title":"Pediatr Crit Care Med"},{"issue":"9","key":"zoi220867r7","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1016\/S1474-4422(18)30231-X","article-title":"Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study.","volume":"17","author":"Bazarian","year":"2018","journal-title":"Lancet Neurol"},{"key":"zoi220867r8","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.resuscitation.2016.01.024","article-title":"Exploratory study of serum ubiquitin carboxyl-terminal esterase L1 and glial fibrillary acidic protein for outcome prognostication after pediatric cardiac arrest.","volume":"101","author":"Fink","year":"2016","journal-title":"Resuscitation"},{"issue":"10","key":"zoi220867r9","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-039323","article-title":"Personalising Outcomes After Child Cardiac Arrest (POCCA): design and recruitment challenges of a multicentre, observational study.","volume":"10","author":"Fink","year":"2020","journal-title":"BMJ Open"},{"issue":"3","key":"zoi220867r10","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.pneurobio.2009.10.020","article-title":"UCHL1 (PGP 9.5): neuronal biomarker and ubiquitin system protein.","volume":"90","author":"Day","year":"2010","journal-title":"Prog Neurobiol"},{"issue":"3","key":"zoi220867r11","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.pneurobio.2011.01.005","article-title":"GFAP in health and disease.","volume":"93","author":"Middeldorp","year":"2011","journal-title":"Prog Neurobiol"},{"issue":"4","key":"zoi220867r12","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S1474-4422(18)30027-9","article-title":"Use of brain diffusion tensor imaging for the prediction of long-term neurological outcomes in patients after cardiac arrest: a multicentre, international, prospective, observational, cohort study.","volume":"17","author":"Velly","year":"2018","journal-title":"Lancet Neurol"},{"issue":"1","key":"zoi220867r13","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1097\/01.ccm.0000728804.84156.c2","article-title":"729: Whole brain diffusion tensor imaging analysis and outcomes following pediatric cardiac arrest.","volume":"49","author":"Devine","year":"2021","journal-title":"Crit Care Med"},{"issue":"10","key":"zoi220867r14","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/s41582-018-0058-z","article-title":"Neurofilaments as biomarkers in neurological disorders.","volume":"14","author":"Khalil","year":"2018","journal-title":"Nat Rev Neurol"},{"issue":"7","key":"zoi220867r15","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1097\/PCC.0000000000002294","article-title":"Circulating neurofilament light chain is associated with survival after pediatric cardiac arrest.","volume":"21","author":"Kirschen","year":"2020","journal-title":"Pediatr Crit Care Med"},{"issue":"1","key":"zoi220867r16","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1001\/jamaneurol.2018.3223","article-title":"Serum neurofilament light chain for prognosis of outcome after cardiac arrest.","volume":"76","author":"Moseby-Knappe","year":"2019","journal-title":"JAMA Neurol"},{"issue":"5","key":"zoi220867r17","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1007\/s00401-017-1707-9","article-title":"Roles of tau protein in health and disease.","volume":"133","author":"Guo","year":"2017","journal-title":"Acta Neuropathol"},{"issue":"5","key":"zoi220867r18","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1002\/ana.v82.5","article-title":"Serum tau and neurological outcome in cardiac arrest.","volume":"82","author":"Mattsson","year":"2017","journal-title":"Ann Neurol"},{"issue":"8","key":"zoi220867r19","doi-asserted-by":"publisher","first-page":"573","DOI":"10.7326\/0003-4819-147-8-200710160-00010","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.","volume":"147","author":"von Elm","year":"2007","journal-title":"Ann Intern Med"},{"issue":"1","key":"zoi220867r20","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/S0022-3476(05)82544-2","article-title":"Assessing the outcome of pediatric intensive care.","volume":"121","author":"Fiser","year":"1992","journal-title":"J Pediatr"},{"issue":"3","key":"zoi220867r21","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.resuscitation.2005.06.005","article-title":"Recommended guidelines for reviewing, reporting, and conducting research on post-resuscitation care: the Utstein style.","volume":"66","author":"Langhelle","year":"2005","journal-title":"Resuscitation"},{"issue":"21","key":"zoi220867r22","doi-asserted-by":"publisher","first-page":"3385","DOI":"10.1161\/01.CIR.0000147236.85306.15","article-title":"Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Councils of Southern Africa).","volume":"110","author":"Jacobs","year":"2004","journal-title":"Circulation"},{"issue":"7","key":"zoi220867r24","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1097\/PCC.0b013e31829760cf","article-title":"Paediatric Index of Mortality 3: an updated model for predicting mortality in pediatric intensive care.","volume":"14","author":"Straney","year":"2013","journal-title":"Pediatr Crit Care Med"},{"issue":"20","key":"zoi220867r26","doi-asserted-by":"publisher","first-page":"1898","DOI":"10.1056\/NEJMoa1411480","article-title":"Therapeutic hypothermia after out-of-hospital cardiac arrest in children.","volume":"372","author":"Moler","year":"2015","journal-title":"N Engl J Med"},{"issue":"4","key":"zoi220867r27","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1056\/NEJMoa1610493","article-title":"Therapeutic hypothermia after in-hospital cardiac arrest in children.","volume":"376","author":"Moler","year":"2017","journal-title":"N Engl J Med"},{"key":"zoi220867r29","doi-asserted-by":"publisher","first-page":"b604","DOI":"10.1136\/bmj.b604","article-title":"Prognosis and prognostic research: developing a prognostic model.","volume":"338","author":"Royston","year":"2009","journal-title":"BMJ"},{"key":"zoi220867r30","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.resuscitation.2016.07.244","article-title":"Unchanged pediatric out-of-hospital cardiac arrest incidence and survival rates with regional variation in North America.","volume":"107","author":"Fink","year":"2016","journal-title":"Resuscitation"},{"issue":"4","key":"zoi220867r31","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1212\/WNL.56.4.481","article-title":"MRI identification of early white matter injury in anoxic-ischemic encephalopathy.","volume":"56","author":"Chalela","year":"2001","journal-title":"Neurology"},{"issue":"1","key":"zoi220867r32","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1007\/s12028-010-9457-8","article-title":"Serial MRI changes in comatose cardiac arrest patients.","volume":"14","author":"Greer","year":"2011","journal-title":"Neurocrit Care"},{"issue":"6","key":"zoi220867r33","doi-asserted-by":"publisher","first-page":"e508","DOI":"10.1097\/CCM.0000000000003070","article-title":"Phenotyping cardiac arrest: bench and bedside characterization of brain and heart injury based on etiology.","volume":"46","author":"Uray","year":"2018","journal-title":"Crit Care Med"},{"issue":"9","key":"zoi220867r34","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1038\/jcbfm.2011.31","article-title":"CSF Bcl-2 and cytochrome C temporal profiles in outcome prediction for adults with severe TBI.","volume":"31","author":"Wagner","year":"2011","journal-title":"J Cereb Blood Flow Metab"},{"issue":"4","key":"zoi220867r35","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-3412","article-title":"Neurobehavioral outcomes in children after out-of-hospital cardiac arrest.","volume":"137","author":"Slomine","year":"2016","journal-title":"Pediatrics"},{"issue":"1","key":"zoi220867r36","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s12028-010-9412-8","article-title":"Sedation confounds outcome prediction in cardiac arrest survivors treated with hypothermia.","volume":"15","author":"Samaniego","year":"2011","journal-title":"Neurocrit Care"},{"issue":"9","key":"zoi220867r37","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1164\/rccm.201411-2125CP","article-title":"Implications of heterogeneity of treatment effect for reporting and analysis of randomized trials in critical care.","volume":"192","author":"Iwashyna","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"zoi220867r38","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1038\/s41581-019-0199-3","article-title":"Prognostic and predictive enrichment in sepsis.","volume":"16","author":"Stanski","year":"2020","journal-title":"Nat Rev Nephrol"},{"issue":"11","key":"zoi220867r39","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.1097\/CCM.0000000000001852","article-title":"Pediatric Sepsis Biomarker Risk Model-II: redefining the pediatric sepsis biomarker risk model with septic shock phenotype.","volume":"44","author":"Wong","year":"2016","journal-title":"Crit Care Med"},{"issue":"8","key":"zoi220867r40","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.9271","article-title":"Derivation and validation of novel phenotypes of multiple organ dysfunction syndrome in critically ill children.","volume":"3","author":"Sanchez-Pinto","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"3","key":"zoi220867r41","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S2213-2600(21)00382-9","article-title":"Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis.","volume":"10","author":"Dahmer","year":"2022","journal-title":"Lancet Respir Med"},{"key":"zoi220867r42","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.resuscitation.2019.03.020","article-title":"Relationships between three and twelve month outcomes in children enrolled in the therapeutic hypothermia after pediatric cardiac arrest trials.","volume":"139","author":"Slomine","year":"2019","journal-title":"Resuscitation"},{"key":"zoi220867r25","author":"Sparrow","year":"2016"},{"key":"zoi220867r28","doi-asserted-by":"crossref","DOI":"10.1002\/9781118548387","volume-title":"Applied Logistic Regression","author":"Hosmer","year":"2013","edition":"3rd ed"},{"key":"zoi220867r23","unstructured":"NIH Staff. What are the requirements for reporting on human study participant age, sex\/gender, and race\/ethnicity? Office of Extramural Research, National Institutes of Health. April 29, 2021. Accessed July 2022. https:\/\/nexus.od.nih.gov\/all\/2021\/04\/29\/what-are-the-requirements-for-reporting-on-human-study-participant-age-sex-gender-and-race-ethnicity"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2795996\/fink_2022_oi_220867_1661882423.37378.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T11:32:46Z","timestamp":1662636766000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2795996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,8]]},"references-count":42,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.30518","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.02.28.22271632","asserted-by":"object"}]},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,8]]}}}