{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:59:10Z","timestamp":1793127550608,"version":"4.5.0"},"reference-count":37,"publisher":"American Medical Association (AMA)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"DOI":"10.1001\/jamanetworkopen.2022.3862","type":"journal-article","created":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T15:55:27Z","timestamp":1648223727000},"page":"e223862","source":"Crossref","is-referenced-by-count":37,"title":["Effect of a Web-Based Management Guide on Risk Factors in Patients With Type 2 Diabetes and Diabetic Kidney Disease"],"prefix":"10.1001","volume":"5","author":[{"given":"Juliana C. N.","family":"Chan","sequence":"first","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"},{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yotsapon","family":"Thewjitcharoen","sequence":"additional","affiliation":[{"name":"Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thy Khue","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Medic Medical Center, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Tan","sequence":"additional","affiliation":[{"name":"Sunway Medical Centre, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yook-Chin","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Sunway University, Selangor, Malaysia"},{"name":"Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chii-Min","family":"Hwu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Du","family":"Jian","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thep","family":"Himathongkam","sequence":"additional","affiliation":[{"name":"Diabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim-Leng","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Mi","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Mirasol","sequence":"additional","affiliation":[{"name":"Section of Endocrinology, Diabetes and Metabolism, St Luke's Medical Center, Quezon City, Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mafauzy","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Medicine, Universiti Sains Malaysia, Kota Bahru, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice P. S.","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald C. W.","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine Y. K.","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risa","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Lau","sequence":"additional","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy W. C.","family":"Fu","sequence":"additional","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Gyoung","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun-Ho","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiu-Chi","family":"Tsang","sequence":"additional","affiliation":[{"name":"Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Tai Po, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric S. H.","family":"Lau","sequence":"additional","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"},{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee-Ling","family":"Lim","sequence":"additional","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"},{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea O. Y.","family":"Luk","sequence":"additional","affiliation":[{"name":"Asia Diabetes Foundation, Shatin, Hong Kong Special Administrative Region (SAR), China"},{"name":"Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"},{"name":"Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2022,3,25]]},"reference":[{"issue":"4","key":"zoi220139r1","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1016\/j.kint.2020.06.024","article-title":"Executive summary of the 2020 KDIGO Diabetes Management in CKD Guideline: evidence-based advances in monitoring and treatment.","volume":"98","author":"de Boer","year":"2020","journal-title":"Kidney Int"},{"issue":"1","key":"zoi220139r2","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2021-002146","article-title":"Incidence and risk factors for mortality and end-stage renal disease in people with type 2 diabetes and diabetic kidney disease: a population-based cohort study in the UK.","volume":"9","author":"Gonz\u00e1lez-P\u00e9rez","year":"2021","journal-title":"BMJ Open Diabetes Res Care"},{"issue":"6","key":"zoi220139r3","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1001\/jama.2014.18574","article-title":"Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis.","volume":"313","author":"Emdin","year":"2015","journal-title":"JAMA"},{"issue":"24","key":"zoi220139r4","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1056\/NEJMoa0802987","article-title":"Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.","volume":"358","author":"Patel","year":"2008","journal-title":"N Engl J Med"},{"issue":"6","key":"zoi220139r5","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.2215\/CJN.04371206","article-title":"Effect of intensive lipid lowering with atorvastatin on renal function in patients with coronary heart disease: the Treating to New Targets (TNT) study.","volume":"2","author":"Shepherd","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"issue":"12","key":"zoi220139r6","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1056\/NEJMoa011161","article-title":"Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.","volume":"345","author":"Brenner","year":"2001","journal-title":"N Engl J Med"},{"issue":"24","key":"zoi220139r7","doi-asserted-by":"publisher","first-page":"2295","DOI":"10.1056\/NEJMoa1811744","article-title":"Canagliflozin and renal outcomes in type 2 diabetes and nephropathy.","volume":"380","author":"Perkovic","year":"2019","journal-title":"N Engl J Med"},{"issue":"15","key":"zoi220139r8","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1056\/NEJMoa2024816","article-title":"Dapagliflozin in patients with chronic kidney disease.","volume":"383","author":"Heerspink","year":"2020","journal-title":"N Engl J Med"},{"issue":"23","key":"zoi220139r9","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1056\/NEJMoa2025845","article-title":"Effect of finerenone on chronic kidney disease outcomes in type 2 diabetes.","volume":"383","author":"Bakris","year":"2020","journal-title":"N Engl J Med"},{"issue":"4","key":"zoi220139r10","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1007\/s00125-019-05078-3","article-title":"Persistent poor glycaemic control in individuals with type 2 diabetes in developing countries: 12 years of real-world evidence of the International Diabetes Management Practices Study (IDMPS).","volume":"63","author":"Aschner","year":"2020","journal-title":"Diabetologia"},{"issue":"11","key":"zoi220139r11","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.2337\/dci19-0003","article-title":"From Hong Kong Diabetes Register to JADE Program to RAMP-DM for data-driven actions.","volume":"42","author":"Chan","year":"2019","journal-title":"Diabetes Care"},{"issue":"12","key":"zoi220139r12","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/S2213-8587(14)70137-8","article-title":"Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme): a cross-sectional study of a prospective cohort.","volume":"2","author":"Yeung","year":"2014","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"9","key":"zoi220139r13","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1111\/dme.2016.33.issue-9","article-title":"Quality of care in patients with diabetic kidney disease in Asia: the Joint Asia Diabetes Evaluation (JADE) registry.","volume":"33","author":"Luk","year":"2016","journal-title":"Diabet Med"},{"issue":"1","key":"zoi220139r14","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s12882-017-0493-x","article-title":"Gaps and barriers in health-care provision for co-morbid diabetes and chronic kidney disease: a cross-sectional study.","volume":"18","author":"Lo","year":"2017","journal-title":"BMC Nephrol"},{"issue":"6","key":"zoi220139r15","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.2337\/dc17-2010","article-title":"Aspects of multicomponent integrated care promote sustained improvement in surrogate clinical outcomes: a systematic review and meta-analysis.","volume":"41","author":"Lim","year":"2018","journal-title":"Diabetes Care"},{"issue":"1","key":"zoi220139r16","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.kint.2020.10.012","article-title":"The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.","volume":"99","author":"Shlipak","year":"2021","journal-title":"Kidney Int"},{"issue":"20","key":"zoi220139r17","doi-asserted-by":"publisher","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.","volume":"310","author":"World Medical Association","year":"2013","journal-title":"JAMA"},{"issue":"9","key":"zoi220139r18","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A new equation to estimate glomerular filtration rate.","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"zoi220139r19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1472-6947-10-26","article-title":"From design to implementation\u2013the Joint Asia Diabetes Evaluation (JADE) program: a descriptive report of an electronic web-based diabetes management program.","volume":"10","author":"Ko","year":"2010","journal-title":"BMC Med Inform Decis Mak"},{"issue":"7","key":"zoi220139r20","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1111\/dme.2009.26.issue-7","article-title":"The Joint Asia Diabetes Evaluation (JADE) program: a web-based program to translate evidence to clinical practice in type 2 diabetes.","volume":"26","author":"Chan","year":"2009","journal-title":"Diabet Med"},{"issue":"10267","key":"zoi220139r21","doi-asserted-by":"publisher","first-page":"2019","DOI":"10.1016\/S0140-6736(20)32374-6","article-title":"The Lancet Commission on diabetes: using data to transform diabetes care and patient lives.","volume":"396","author":"Chan","year":"2021","journal-title":"Lancet"},{"issue":"9677","key":"zoi220139r22","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1016\/S0140-6736(09)60697-8","article-title":"Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials.","volume":"373","author":"Ray","year":"2009","journal-title":"Lancet"},{"issue":"9607","key":"zoi220139r23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0140-6736(08)60104-X","article-title":"Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis.","volume":"371","author":"Kearney","year":"2008","journal-title":"Lancet"},{"issue":"6","key":"zoi220139r24","doi-asserted-by":"publisher","first-page":"977","DOI":"10.2337\/dc08-1908","article-title":"Effects of structured versus usual care on renal endpoint in type 2 diabetes: the SURE study: a randomized multicenter translational study.","volume":"32","author":"Chan","year":"2009","journal-title":"Diabetes Care"},{"issue":"3","key":"zoi220139r25","first-page":"1","article-title":"mice: multivariate imputation by chained equations in R.","volume":"45","author":"van Buuren","year":"2011","journal-title":"J Stat Softw"},{"issue":"4","key":"zoi220139r26","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1093\/biomet\/86.4.948","article-title":"Miscellanea: small-sample degrees of freedom with multiple imputation.","volume":"86","author":"Barnard","year":"1999","journal-title":"Biometrika"},{"issue":"4","key":"zoi220139r28","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1016\/j.kint.2016.11.023","article-title":"Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits.","volume":"91","author":"Oellgaard","year":"2017","journal-title":"Kidney Int"},{"issue":"1","key":"zoi220139r29","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/j.kint.2020.08.012","article-title":"Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type 2 diabetes.","volume":"99","author":"Ueki","year":"2020","journal-title":"Kidney Int"},{"issue":"1","key":"zoi220139r30","doi-asserted-by":"publisher","first-page":"e19","DOI":"10.1016\/j.kisu.2019.11.002","article-title":"Framework for establishing integrated kidney care programs in low- and middle-income countries.","volume":"10","author":"Tonelli","year":"2020","journal-title":"Kidney Int Suppl (2011)"},{"issue":"4","key":"zoi220139r31","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.7557","article-title":"Effects of a technology-assisted integrated diabetes care program on cardiometabolic risk factors among patients with type 2 diabetes in the Asia-Pacific region: the JADE program randomized clinical trial.","volume":"4","author":"Lim","year":"2021","journal-title":"JAMA Netw Open"},{"key":"zoi220139r32","doi-asserted-by":"publisher","first-page":"S40","DOI":"10.2337\/dc21-S004","article-title":"4. Comprehensive medical evaluation and assessment of comorbidities: Standards of Medical Care in Diabetes\u20132021.","volume":"44","author":"American Diabetes Association","year":"2021","journal-title":"Diabetes Care"},{"issue":"2","key":"zoi220139r33","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/S2213-8587(17)30239-5","article-title":"Diabetes structured self-management education programmes: a narrative review and current innovations.","volume":"6","author":"Chatterjee","year":"2018","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"3","key":"zoi220139r34","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1111\/dme.2017.34.issue-3","article-title":"A multicentre demonstration project to evaluate the effectiveness and acceptability of the web-based Joint Asia Diabetes Evaluation (JADE) programme with or without nurse support in Chinese patients with type 2 diabetes.","volume":"34","author":"Tutino","year":"2017","journal-title":"Diabet Med"},{"issue":"10085","key":"zoi220139r35","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1016\/S0140-6736(17)30058-2","article-title":"Type 2 diabetes.","volume":"389","author":"Chatterjee","year":"2017","journal-title":"Lancet"},{"key":"zoi220139r36","doi-asserted-by":"publisher","first-page":"S295","DOI":"10.1016\/S0168-8227(14)70733-8","article-title":"Delivery of integrated diabetes care using logistics and information technology\u2013the Joint Asia Diabetes Evaluation (JADE) program.","volume":"106","author":"Chan","year":"2014","journal-title":"Diabetes Res Clin Pract"},{"issue":"10","key":"zoi220139r37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003367","article-title":"Association of technologically assisted integrated care with clinical outcomes in type 2 diabetes in Hong Kong using the prospective JADE Program: a retrospective cohort analysis.","volume":"17","author":"Lim","year":"2020","journal-title":"PLoS Med"},{"key":"zoi220139r27","unstructured":"R Core Team. The R project for statistical computing. Accessed January 17, 2020. https:\/\/www.R-project.org\/"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2790519\/chan_2022_oi_220139_1648059404.97368.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,25]],"date-time":"2022-03-25T15:55:34Z","timestamp":1648223734000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2790519"}},"subtitle":["A JADE Randomized Clinical Trial"],"short-title":[],"issued":{"date-parts":[[2022,3,25]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2022.3862","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,25]]}}}