{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:27:04Z","timestamp":1782275224867,"version":"3.54.5"},"reference-count":41,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi221248-4\"><jats:title>Importance<\/jats:title><jats:p>College students in the US have been heavily affected by the COVID-19 pandemic. In addition to increased rates of depression and anxiety, college students have faced unprecedented stressors, such as geographic relocation and abrupt conversion from in-person classes to online classes.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-5\"><jats:title>Objective<\/jats:title><jats:p>To study the association between course delivery model and psychological distress among US college students.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This cross-sectional analysis used national data from the American College Health Association\u2013National College Health Assessment III data set. Data were gathered from a web-based survey administered from January to early June 2021 to full-time US college students attending 4-year programs.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-7\"><jats:title>Exposure<\/jats:title><jats:p>Course delivery model was self-reported.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-8\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Psychological distress was measured using the Kessler Screening Scale for Psychological Distress.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-9\"><jats:title>Results<\/jats:title><jats:p>This study evaluated 59\u202f250 full-time undergraduate students (68.1% women; 51.5% White students; mean [SD] age, 21.2 [4.3] years); 3.5% attended fully in-person classes, 61.2% attended fully online classes, and 35.3% attended a mixed format of in-person and online classes. Students who attended classes fully online reported higher levels of psychological distress than those who attended a mix of online and in-person classes (<jats:italic>b<\/jats:italic>\u2009=\u20090.76 [99% CI, 0.64-0.88]; <jats:italic>P<\/jats:italic>\u2009&amp;amp;lt;\u2009.001). This association remained significant after controlling for geographic region, year in school, gender, race and ethnicity, food security, current anxiety and\/or depressive disorders, COVID-19 concerns, and residence (living on campus, off campus with family, or other off-campus arrangements) (<jats:italic>b<\/jats:italic>\u2009=\u20090.18 [99% CI, 0.04-0.31]; <jats:italic>P<\/jats:italic>\u2009=\u2009.001), as well as time spent socializing with friends (<jats:italic>b<\/jats:italic>\u2009=\u20090.13 [99% CI, 0.002-0.26]; <jats:italic>P<\/jats:italic>\u2009=\u2009.009).<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi221248-10\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>The findings of this study suggest that mental health professionals may wish to consider the association of course delivery models with mental health outcomes when working with college students. Colleges should be aware of the mental health burden associated with attending fully online classes and consider possible in-person components and supports for students.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2022.44270","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T16:32:50Z","timestamp":1669825970000},"page":"e2244270","source":"Crossref","is-referenced-by-count":16,"title":["Association Between College Course Delivery Model and Rates of Psychological Distress During the COVID-19 Pandemic"],"prefix":"10.1001","volume":"5","author":[{"given":"Abdelrahman","family":"ElTohamy","sequence":"first","affiliation":[{"name":"Harvard Medical School, Boston, Massachusetts"},{"name":"Department of Psychiatry, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Harvard Medical School, Boston, 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R, Passel? JS, Cohn? D. A majority of young adults in the U.S. live with their parents for the first time since the Great Depression. Pew Research Center. September 4, 2020. Accessed November 26, 2021. https:\/\/www.pewresearch.org\/fact-tank\/2020\/09\/04\/a-majority-of-young-adults-in-the-u-s-live-with-their-parents-for-the-first-time-since-the-great-depression\/"},{"key":"zoi221248r8","unstructured":"Cameron? M, Lacy? TA, Siegel? P, . 2019\u201320 National Postsecondary Student Aid Study (NPSAS:20): first look at the impact of the coronavirus (COVID-19) pandemic on undergraduate student enrollment, housing, and finances (preliminary data). National Center for Education Statistics. June 16, 2021. Accessed March 7, 2022. https:\/\/nces.ed.gov\/pubsearch\/pubsinfo.asp?pubid=2021456"},{"key":"zoi221248r9","unstructured":"National Center for Education Statistics. Table 3: number and percentage distribution of students enrolled at Title IV institutions, by control of institution, student level, level of institution, distance education status of student, and distance education status of institution: United States, fall 2020. Published 2021. Accessed March 7, 2022. https:\/\/nces.ed.gov\/ipeds\/search\/ViewTable?tableId=29450"},{"key":"zoi221248r23","unstructured":"StataCorp. Stata statistical software. Release 17. StataCorp LLC; 2021. Accessed November 13, 2021. https:\/\/www.stata.com\/"},{"key":"zoi221248r28","unstructured":"Drea? J. Online? in person? the power of letting students choose. Harvard Business Publishing. Published March 19, 2021. Accessed March 31, 2022. https:\/\/hbsp.harvard.edu\/inspiring-minds\/online-in-person-the-power-of-letting-students-choose"},{"key":"zoi221248r36","unstructured":"Reyes? JF. More New Jersey schools are going remote for the beginning of 2022. The Philadelphia Inquirer. Published January 1, 2022. 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