{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T17:04:17Z","timestamp":1793207057784,"version":"4.5.0"},"reference-count":25,"publisher":"American Medical Association (AMA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"Importance<\/jats:title>In part to prevent the harms associated with dental opioid prescriptions, most states have enacted policies limiting the duration of opioid prescriptions for acute pain. Whether these limits are associated with changes in the duration of opioid prescriptions written by dentists is unclear.<\/jats:p><\/jats:sec>Objective<\/jats:title>To evaluate the association between state opioid prescribing limits and the duration of opioid prescriptions from dentists.<\/jats:p><\/jats:sec>Design, Setting, and Participants<\/jats:title>This difference-in-differences cross-sectional study used data from the IQVIA Longitudinal Prescription Database, an all-payer database reporting prescription dispensing from 92% of retail pharmacies in the US. The sample included opioid prescriptions from dentists dispensed to children aged 0 to 17 years and adults 18 years or older from January 2014 through February 2020. Treatment states were those that implemented limits between January 2016 and December 2018. Control states were those that did not implement limits during the study period. Data on opioid prescribing limits were derived from the Prescription Drug Abuse Policy System. Data were analyzed from January 1 to September 30, 2022.<\/jats:p><\/jats:sec>Exposures<\/jats:title>State opioid prescribing limits.<\/jats:p><\/jats:sec>Main Outcomes and Measures<\/jats:title>The outcome was opioid prescription duration, as measured by days\u2019 supply. The association between limits and duration was evaluated using a linear model with a 2-way fixed-effects specification. Covariates included patient characteristics, prescription characteristics, and indicators of implementation of prescription drug monitoring program use mandates. Separate analyses of data from adults and children were conducted owing to differences in the number of treatment states and restrictiveness of limits by age.<\/jats:p><\/jats:sec>Results<\/jats:title>The adult analysis included 56\u202f607 314 opioid prescriptions for 34\u202f364\u202f775 patients (18\u202f448\u202f788 females [53.7%]; mean [SD] age at the earliest fill, 44.0 [17.4] years) in 22 treatment states and 12 control states. The child analysis included 3\u202f720\u202f837 opioid prescriptions for 3\u202f165\u202f880 patients (1\u202f740\u202f449 females [55.0%]; mean [SD] age at the earliest fill, 14.4 [3.5] years) in 23 treatment states and 12 control states. In both analyses, the median (25th-75th percentile) duration of opioid prescriptions was 3.0 (2-5) days. Implementation of limits, most of which allowed up to a 7-day supply of opioids, was not associated with changes in the duration of opioid prescriptions for adults (mean days\u2019 supply: \u22120.06 days; 95% CI, \u22120.11 to &amp;lt;0.001 days) or children (mean days\u2019 supply: \u22120.07 days; 95% CI, \u22120.15 to 0.02 days).<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>In this study of national pharmacy dispensing data, opioid prescribing limits were not associated with changes in the duration of opioid prescriptions from dentists. Future research should investigate the potential role of alternative interventions in reducing opioid prescribing by dentists.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2022.50409","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T16:06:37Z","timestamp":1673453197000},"page":"e2250409","source":"Crossref","is-referenced-by-count":7,"title":["Association Between State Opioid Prescribing Limits and Duration of Opioid Prescriptions From Dentists"],"prefix":"10.1001","volume":"6","author":[{"given":"Kao-Ping","family":"Chua","sequence":"first","affiliation":[{"name":"Susan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor"},{"name":"Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuy D.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer F.","family":"Waljee","sequence":"additional","affiliation":[{"name":"Section of Plastic Surgery, Department of Surgery, University of Michigan Medical School, Ann Arbor"},{"name":"Michigan Opioid Prescribing Engagement Network, Institute for Healthcare Policy and Innovation, University of Michigan Medical School, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romesh P.","family":"Nalliah","sequence":"additional","affiliation":[{"name":"University of Michigan School of Dentistry, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad M.","family":"Brummett","sequence":"additional","affiliation":[{"name":"Michigan Opioid Prescribing Engagement Network, Institute for Healthcare Policy and Innovation, University of Michigan Medical School, Ann Arbor"},{"name":"University of Michigan School of Dentistry, Ann Arbor"},{"name":"Division of Pain Medicine, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"issue":"3","key":"zoi221431r1","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.amepre.2021.09.017","article-title":"Distribution of opioid prescribing and high-risk prescribing among U.S. dentists in 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