{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T03:29:07Z","timestamp":1791602947370,"version":"4.3.4"},"reference-count":31,"publisher":"American Medical Association (AMA)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi230835-4\"><jats:title>Importance<\/jats:title><jats:p>Medical and nonmedical cannabis use and cannabis use disorders (CUD) have increased with increasing cannabis legalization. However, the prevalence of CUD among primary care patients who use cannabis for medical or nonmedical reasons is unknown for patients in states with legal recreational use.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-5\"><jats:title>Objective<\/jats:title><jats:p>To estimate the prevalence and severity of CUD among patients who report medical use only, nonmedical use only, and both reasons for cannabis use in a state with legal recreational use.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-6\"><jats:title>Design, Setting, and Participants<\/jats:title><jats:p>This cross-sectional survey study took place at an integrated health system in Washington State. Among 108\u202f950 adult patients who completed routine cannabis screening from March 2019 to September 2019, 5000 were selected for a confidential cannabis survey using stratified random sampling for frequency of past-year cannabis use and race and ethnicity. Among 1688 respondents, 1463 reporting past 30-day cannabis use were included in the study.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-7\"><jats:title>Exposure<\/jats:title><jats:p>Patient survey\u2013reported reason for cannabis use in the past 30 days: medical use only, nonmedical use only, and both reasons.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-8\"><jats:title>Main Outcomes and Measures<\/jats:title><jats:p>Patient responses to the Composite International Diagnostic Interview-Substance Abuse Module for CUD, corresponding to <jats:italic>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition<\/jats:italic> CUD severity (0-11 symptoms) were categorized as any CUD (\u22652 symptoms) and moderate to severe CUD (\u22654 symptoms). Adjusted analyses were weighted for survey stratification and nonresponse for primary care population estimates and compared prevalence of CUD across reasons for cannabis use.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-9\"><jats:title>Results<\/jats:title><jats:p>Of 1463 included primary care patients (weighted mean [SD] age, 47.4 [16.8] years; 748 [weighted proportion, 61.9%] female) who used cannabis, 42.4% (95% CI, 31.2%-54.3%) reported medical use only, 25.1% (95% CI, 17.8%-34.2%) nonmedical use only, and 32.5% (95% CI, 25.3%-40.8%) both reasons for use. The prevalence of CUD was 21.3% (95% CI, 15.4%-28.6%) and did not vary across groups. The prevalence of moderate to severe CUD was 6.5% (95% CI, 5.0%-8.6%) and differed across groups: 1.3% (95% CI, 0.0%-2.8%) for medical use, 7.2% (95% CI, 3.9%-10.4%) for nonmedical use, and 7.5% (95% CI, 5.7%-9.4%) for both reasons for use (<jats:italic>P<\/jats:italic>\u2009=\u2009.01).<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi230835-10\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>In this cross-sectional study of primary care patients in a state with legal recreational cannabis use, CUD was common among patients who used cannabis. Moderate to severe CUD was more prevalent among patients who reported any nonmedical use. These results underscore the importance of assessing patient cannabis use and CUD symptoms in medical settings.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2023.28934","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T15:31:49Z","timestamp":1693323109000},"page":"e2328934","source":"Crossref","is-referenced-by-count":69,"title":["Prevalence of Cannabis Use Disorder and Reasons for Use Among Adults in a US State Where Recreational Cannabis Use Is Legal"],"prefix":"10.1001","volume":"6","author":[{"given":"Gwen T.","family":"Lapham","sequence":"first","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"},{"name":"Department of Health Systems and Population Health, University of Washington, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa E.","family":"Matson","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"},{"name":"Department of Health Systems and Population Health, University of Washington, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer F.","family":"Bobb","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casey","family":"Luce","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malia M.","family":"Oliver","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah K.","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharine A.","family":"Bradley","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Washington Health Research Institute, Seattle"},{"name":"Department of Health Systems and Population Health, University of Washington, Seattle"},{"name":"Department of Medicine, University of Washington, Seattle"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2023,8,29]]},"reference":[{"key":"zoi230835r2","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.copsyc.2021.03.005","article-title":"Trends over time in adult cannabis use: a review of recent findings.","volume":"38","author":"Hasin","year":"2021","journal-title":"Curr Opin Psychol"},{"issue":"10","key":"zoi230835r3","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/S2215-0366(16)30208-5","article-title":"Marijuana use and use disorders in adults in the USA, 2002-14: analysis of annual cross-sectional surveys.","volume":"3","author":"Compton","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"zoi230835r5","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2019.102658","article-title":"Prevalence and forms of cannabis use in legal vs. illegal recreational cannabis markets.","volume":"76","author":"Goodman","year":"2020","journal-title":"Int J Drug Policy"},{"issue":"3","key":"zoi230835r6","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1086\/721267","article-title":"Comparative effects of recreational and medical marijuana laws on drug use among adults and adolescents.","volume":"65","author":"Hollingsworth","year":"2022","journal-title":"J Law Econ"},{"key":"zoi230835r9","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.drugalcdep.2018.01.022","article-title":"Trends in and correlates of medical marijuana use among adults in the United States.","volume":"186","author":"Han","year":"2018","journal-title":"Drug Alcohol Depend"},{"key":"zoi230835r10","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/j.addbeh.2016.05.015","article-title":"Comparing adults who use cannabis medically with those who use recreationally: results from a national sample.","volume":"61","author":"Lin","year":"2016","journal-title":"Addict Behav"},{"issue":"2","key":"zoi230835r11","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1001\/jama.2016.18900","article-title":"Use of marijuana for medical purposes among adults in the United States.","volume":"317","author":"Compton","year":"2017","journal-title":"JAMA"},{"issue":"2","key":"zoi230835r12","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1037\/adb0000725","article-title":"Prevalence of medical and nonmedical cannabis use among veterans in primary care.","volume":"36","author":"Browne","year":"2022","journal-title":"Psychol Addict Behav"},{"issue":"5","key":"zoi230835r13","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.11677","article-title":"Comparison of medical cannabis use reported on a confidential survey vs documented in the electronic health record among primary care patients.","volume":"5","author":"Lapham","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"23","key":"zoi230835r14","doi-asserted-by":"publisher","first-page":"2219","DOI":"10.1056\/NEJMra1402309","article-title":"Adverse health effects of marijuana use.","volume":"370","author":"Volkow","year":"2014","journal-title":"N Engl J Med"},{"issue":"12","key":"zoi230835r15","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1001\/jamapsychiatry.2015.1858","article-title":"Prevalence of marijuana use disorders in the United States between 2001-2002 and 2012-2013.","volume":"72","author":"Hasin","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"zoi230835r16","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2019.107621","article-title":"Cannabis use disorder among people using cannabis daily\/almost daily in the United States, 2002-2016.","volume":"205","author":"Santaella-Tenorio","year":"2019","journal-title":"Drug Alcohol Depend"},{"issue":"1","key":"zoi230835r17","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/add.12703","article-title":"What has research over the past two decades revealed about the adverse health effects of recreational cannabis use?","volume":"110","author":"Hall","year":"2015","journal-title":"Addiction"},{"issue":"10208","key":"zoi230835r18","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1016\/S0140-6736(19)31789-1","article-title":"Public health implications of legalising the production and sale of cannabis for medicinal and recreational use.","volume":"394","author":"Hall","year":"2019","journal-title":"Lancet"},{"issue":"2","key":"zoi230835r19","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1001\/jamapsychiatry.2019.3254","article-title":"Association between recreational marijuana legalization in the United States and changes in marijuana use and cannabis use disorder from 2008 to 2016.","volume":"77","author":"Cerd\u00e1","year":"2020","journal-title":"JAMA Psychiatry"},{"issue":"6","key":"zoi230835r20","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1001\/jamapsychiatry.2017.0724","article-title":"US adult illicit cannabis use, cannabis use disorder, and medical marijuana laws: 1991-1992 to 2012-2013.","volume":"74","author":"Hasin","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"zoi230835r21","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2019.05.008","article-title":"Cannabis use disorders among adults in the United States during a time of increasing use of cannabis.","volume":"204","author":"Compton","year":"2019","journal-title":"Drug Alcohol Depend"},{"issue":"11","key":"zoi230835r22","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.39772","article-title":"Validity of the single-item screen-cannabis (SIS-C) for cannabis use disorder screening in routine care.","volume":"5","author":"Matson","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"3","key":"zoi230835r23","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/0376-8716(96)01249-5","article-title":"Comparing assessments of DSM-IV substance dependence disorders using CIDI-SAM and SCAN.","volume":"41","author":"Compton","year":"1996","journal-title":"Drug Alcohol Depend"},{"issue":"1","key":"zoi230835r24","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1093\/biostatistics\/kxh020","article-title":"Estimating marginal and incremental effects on health outcomes using flexible link and variance function models.","volume":"6","author":"Basu","year":"2005","journal-title":"Biostatistics"},{"issue":"9","key":"zoi230835r26","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1007\/s11606-018-4480-0","article-title":"The form and content of cannabis products in the United States.","volume":"33","author":"Steigerwald","year":"2018","journal-title":"J Gen Intern Med"},{"issue":"3","key":"zoi230835r27","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.2106","article-title":"Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults: a randomized clinical trial.","volume":"5","author":"Gilman","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"5","key":"zoi230835r29","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.16283","article-title":"Psychometric performance of a substance use symptom checklist to help clinicians assess substance use disorder in primary care.","volume":"6","author":"Matson","year":"2023","journal-title":"JAMA Netw Open"},{"issue":"8","key":"zoi230835r30","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.2105\/AJPH.2016.303198","article-title":"Population survey features and response rates: a randomized experiment.","volume":"106","author":"Guo","year":"2016","journal-title":"Am J Public Health"},{"issue":"1","key":"zoi230835r31","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1186\/s12889-020-8241-8","article-title":"Factors associated with health survey response among young employees: a register-based study using online, mailed and telephone interview data collection methods.","volume":"20","author":"Lallukka","year":"2020","journal-title":"BMC Public Health"},{"key":"zoi230835r25","doi-asserted-by":"crossref","DOI":"10.1093\/med\/9780199685028.001.0001","volume-title":"Economic Evaluation in Clinical Trials","author":"Glick","year":"2014"},{"key":"zoi230835r28","volume-title":"The Health Effects of Cannabis and Cannabinoids: the Current State of Evidence and Recommendations for Research","author":"National Academies of Sciences Engineering and Medicine","year":"2017"},{"key":"zoi230835r1","unstructured":"Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: results from the 2020 National Survey on Drug Use and Health. Vol. HHS Publication No. PEP21-07-01-003. 2021. Accessed February 14, 2023. https:\/\/www.samhsa.gov\/data\/"},{"key":"zoi230835r4","unstructured":"National Conference of State Legislatures. State medical marijuana laws. Accessed June 25, 2021. https:\/\/www.ncsl.org\/research\/health\/state-medical-marijuana-laws.aspx"},{"key":"zoi230835r7","unstructured":"Bureau? UC. State population totals and components of change: 2020-2021. Accessed December 5, 2022. https:\/\/www.census.gov\/data\/tables\/time-series\/demo\/popest\/2020s-state-total.html"},{"key":"zoi230835r8","unstructured":"Britannica. State-by-state recreational marijuana laws. Accessed December 5, 2022. https:\/\/marijuana.procon.org\/legal-recreational-marijuana-states-and-dc\/"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2808874\/lapham_2023_oi_230835_1692735460.6559.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T15:31:54Z","timestamp":1693323114000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2808874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,29]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.28934","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,29]]}}}