{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:17:24Z","timestamp":1790007444143,"version":"4.0.1"},"reference-count":115,"publisher":"American Medical Association (AMA)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"<jats:sec id=\"ab-zoi240589-4\"><jats:title>Importance<\/jats:title><jats:p>Interventions that address needs such as low income, housing instability, and safety are increasingly appearing in the health care sector as part of multifaceted efforts to improve health and health equity, but evidence relevant to scaling these social needs interventions is limited.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi240589-5\"><jats:title>Objective<\/jats:title><jats:p>To summarize the intensity and complexity of social needs interventions included in randomized clinical trials (RCTs) and assess whether these RCTs were designed to measure the causal effects of intervention components on behavioral, health, or health care utilization outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi240589-6\"><jats:title>Evidence Review<\/jats:title><jats:p>This review of a scoping review was based on a Patient-Centered Outcomes Research Institute\u2013funded evidence map of English-language US-based RCTs of social needs interventions published between January 1, 1995, and April 6, 2023. Studies were assessed for features related to intensity (defined using modal values as providing as-needed interaction, 8 participant contacts or more, contacts occurring every 2 weeks or more often, encounters of 30 minutes or longer, contacts over 6 months or longer, or home visits), complexity (defined as addressing multiple social needs, having dedicated staff, involving multiple intervention components or practitioners, aiming to change multiple participant behaviors [knowledge, action, or practice], requiring or providing resources or active assistance with resources, and permitting tailoring), and the ability to assess causal inferences of components (assessing interventions, comparators, and context).<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi240589-7\"><jats:title>Findings<\/jats:title><jats:p>This review of a scoping review of social needs interventions identified 77 RCTs in 93 publications with a total of 135\u202f690 participants. Most articles (68 RCTs [88%]) reported 1 or more features of high intensity. All studies reported 1 or more features indicative of high complexity. Because most studies compared usual care with multicomponent interventions that were moderately or highly dependent on context and individual factors, their designs permitted causal inferences about overall effectiveness but not about individual components.<\/jats:p><\/jats:sec><jats:sec id=\"ab-zoi240589-8\"><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Social needs interventions are complex, intense, and include multiple components. Our findings suggest that RCTs of these interventions address overall intervention effectiveness but are rarely designed to distinguish the causal effects of specific components despite being resource intensive. Future studies with hybrid effectiveness-implementation and sequential designs, and more standardized reporting of intervention intensity and complexity could help stakeholders assess the return on investment of these interventions.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.17994","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T15:35:23Z","timestamp":1718984123000},"page":"e2417994","source":"Crossref","is-referenced-by-count":9,"title":["Evaluating Intensity, Complexity, and Potential for Causal Inference in Social Needs Interventions"],"prefix":"10.1001","volume":"7","author":[{"given":"Meera","family":"Viswanathan","sequence":"first","affiliation":[{"name":"RTI International, Research Triangle Park, North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"RTI International, Research Triangle Park, North 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