{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T05:13:50Z","timestamp":1773119630275,"version":"3.50.1"},"reference-count":32,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"Importance<\/jats:title>In the context of emerging SARS-CoV-2 variants or lineages and new vaccines, it is key to accurately monitor COVID-19 vaccine effectiveness (CVE) to inform vaccination campaigns.<\/jats:p><\/jats:sec>Objective<\/jats:title>To estimate the effectiveness of COVID-19 vaccines administered in autumn and winter 2022 to 2023 against symptomatic SARS-CoV-2 infection (with all circulating viruses and XBB lineage in particular) among people aged 60 years or older in Europe, and to compare different CVE approaches across the exposed and reference groups used.<\/jats:p><\/jats:sec>Design, Setting, and Participants<\/jats:title>This case-control study obtained data from VEBIS (Vaccine Effectiveness, Burden and Impact Studies), a multicenter study that collects COVID-19 and influenza data from 11 European sites: Croatia; France; Germany; Hungary; Ireland; Portugal; the Netherlands; Romania; Spain, national; Spain, Navarre region; and Sweden. Participants were primary care patients aged 60 years or older with acute respiratory infection symptoms who were recruited at the 11 sites after the start of the COVID-19 vaccination campaign from September 2022 to August 2023. Cases and controls were defined as patients with positive and negative, respectively, reverse transcription\u2013polymerase chain reaction (RT-PCR) test results.<\/jats:p><\/jats:sec>Exposures<\/jats:title>The exposure was COVID-19 vaccination. The exposure group consisted of patients who received a COVID-19 vaccine during the autumn and winter 2022 to 2023 vaccination campaign and 14 days or more before symptom onset. Reference group included patients who were not vaccinated during or in the 6 months before the 2022 to 2023 campaign (seasonal CVE), those who were never vaccinated (absolute CVE), and those who were vaccinated with at least the primary series 6 months or more before the campaign (relative CVE). For relative CVE of second boosters, patients receiving their second booster during the campaign were compared with those receiving 1 booster 6 months or more before the campaign.<\/jats:p><\/jats:sec>Main Outcomes and Measures<\/jats:title>The outcome was RT-PCR\u2013confirmed, medically attended, symptomatic SARS-CoV-2 infection. Four CVE estimates were generated: seasonal, absolute, relative, and relative of second boosters. CVE was estimated using logistic regression, adjusting for study site, symptom onset date, age, chronic condition, and sex.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 9308 primary care patients were included, with 1687 cases (1035 females; median [IQR] age, 71 [65-79] years) and 7621 controls (4619 females [61%]; median [IQR] age, 71 [65-78] years). Within 14 to 89 days after vaccination, seasonal CVE was 29% (95% CI, 14%-42%), absolute CVE was 39% (95% CI, 6%-60%), relative CVE was 31% (95% CI, 15% to 44%), and relative CVE of second boosters was 34% (95% CI, 18%-47%) against all SARS-CoV-2 variants. In the same interval, seasonal CVE was 44% (95% CI, \u221210% to 75%), absolute CVE was 52% (95% CI, \u221223% to 82%), relative CVE was 47% (95% CI, \u22128% to 77%), and relative CVE of second boosters was 46% (95% CI, \u221213% to 77%) during a period of high XBB circulation. Estimates decreased with time since vaccination, with no protection from 180 days after vaccination.<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>In this case-control study among older Europeans, all CVE approaches suggested that COVID-19 vaccines administered in autumn and winter 2022 to 2023 offered at least 3 months of protection against symptomatic, medically attended, laboratory-confirmed SARS-CoV-2 infection. The effectiveness of new COVID-19 vaccines against emerging SARS-CoV-2 variants should be continually monitored using CVE seasonal approaches.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.19258","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T15:02:28Z","timestamp":1719846148000},"page":"e2419258","source":"Crossref","is-referenced-by-count":9,"title":["COVID-19 Vaccine Effectiveness in Autumn and Winter 2022 to 2023 Among Older Europeans"],"prefix":"10.1001","volume":"7","author":[{"given":"Charlotte","family":"Laniece Delaunay","sequence":"first","affiliation":[{"name":"Epidemiology Department, Epiconcept, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Mazagatos","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain"},{"name":"Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"Mart\u00ednez-Baz","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra\u2013IdiSNA, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerg\u0151","family":"T\u00fari","sequence":"additional","affiliation":[{"name":"National Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luise","family":"Goerlitz","sequence":"additional","affiliation":[{"name":"Department for Infectious Disease Epidemiology, Unit 36 Respiratory Infections, Robert Koch Institute, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Domegan","sequence":"additional","affiliation":[{"name":"Health Service Executive-Health Protection Surveillance Centre, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Meijer","sequence":"additional","affiliation":[{"name":"Centre for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Epidemiology Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"No\u00e9mie","family":"S\u00e8ve","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM), Institut Pierre Louis d'\u00e9pid\u00e9miologie et de Sant\u00e9 Publique (IPLESP UMRS 1136), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Ili\u0107","sequence":"additional","affiliation":[{"name":"Division for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neus","family":"Latorre-Margalef","sequence":"additional","affiliation":[{"name":"Department of Microbiology, The Public Health Agency of Sweden, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Lazar","sequence":"additional","affiliation":[{"name":"National Influenza Centre, \u201cCantacuzino\u201d National Military-Medical Institute for Research and Development, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marine","family":"Maurel","sequence":"additional","affiliation":[{"name":"Epidemiology Department, Epiconcept, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryse","family":"Melo","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Influenza and Other Respiratory Virus, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanca","family":"Andreu Ivorra","sequence":"additional","affiliation":[{"name":"Servicio de Epidemiolog\u00eda, Secci\u00f3n de Vigilancia Epidemiol\u00f3gica, Consejer\u00eda de Salud de Murcia, Murcia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Itziar","family":"Casado","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra\u2013IdiSNA, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit Krisztina","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"National Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silke","family":"Buda","sequence":"additional","affiliation":[{"name":"Department for Infectious Disease Epidemiology, Unit 36 Respiratory Infections, Robert Koch Institute, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlene","family":"Bennett","sequence":"additional","affiliation":[{"name":"National Virus Reference Laboratory, University College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marit","family":"de Lange","sequence":"additional","affiliation":[{"name":"Centre for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Guiomar","sequence":"additional","affiliation":[{"name":"Reference Laboratory for Influenza and Other Respiratory Virus, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Enouf","sequence":"additional","affiliation":[{"name":"Institut Pasteur, Centre National de R\u00e9f\u00e9rence Virus des Infections Respiratoires (CNR VIR), Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Mlinari\u0107","sequence":"additional","affiliation":[{"name":"Division for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tove","family":"Samuelsson Hagey","sequence":"additional","affiliation":[{"name":"Department of Microbiology, The Public Health Agency of Sweden, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sorin","family":"Dinu","sequence":"additional","affiliation":[{"name":"National Influenza Centre, \u201cCantacuzino\u201d National Military-Medical Institute for Research and Development, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mercedes","family":"Rumayor","sequence":"additional","affiliation":[{"name":"\u00c1rea de Enfermedades Transmisibles, Subdirecci\u00f3n General de Vigilancia en Salud P\u00fablica, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Castilla","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Navarra\u2013IdiSNA, Pamplona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrix","family":"Oroszi","sequence":"additional","affiliation":[{"name":"National Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"D\u00fcrrwald","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Unit 17 Influenza and Other Respiratory Viruses, Robert Koch Institute, Berlin, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"O\u2019Donnell","sequence":"additional","affiliation":[{"name":"Health Service Executive-Health Protection Surveillance Centre, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari\u00ebtte","family":"Hooiveld","sequence":"additional","affiliation":[{"name":"Nivel (Netherlands Institute for Health Services Research), Utrecht, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"Gomez","sequence":"additional","affiliation":[{"name":"Epidemiology Department, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Falchi","sequence":"additional","affiliation":[{"name":"Laboratoire de Virologie, UR7310 Campus Grimaldi, Universit\u00e9 de Corse, Corte, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanja","family":"Kure\u010di\u0107 Filipovi\u0107","sequence":"additional","affiliation":[{"name":"Division for Epidemiology of Communicable Diseases, Croatian Institute of Public Health, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Dillner","sequence":"additional","affiliation":[{"name":"Department of Microbiology, The Public Health Agency of Sweden, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodica","family":"Popescu","sequence":"additional","affiliation":[{"name":"National Center for Communicable Diseases Surveillance and Control, National Institute of Public Health, Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Bacci","sequence":"additional","affiliation":[{"name":"European Centre for Disease Prevention and Control, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlena","family":"Kaczmarek","sequence":"additional","affiliation":[{"name":"European Centre for Disease Prevention and Control, Stockholm, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Kissling","sequence":"additional","affiliation":[{"name":"Epidemiology Department, Epiconcept, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"VEBIS Primary Care Vaccine Effectiveness Group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virtudes","family":"Gallardo Garc\u00eda","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esteban","family":"Perez Morilla","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Pedrosa Corral","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Garc\u00eda V\u00e1zquez","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Milagro-Beamonte","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Fernandez Iba\u00f1ez","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Margolles Martins","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaume","family":"Gim\u00e9nez Duran","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bartolom\u00e9","family":"Sastre Palou","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"L\u00f3pez Causap\u00e9","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Javier","family":"Viloria Raymundo","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom\u00e1s","family":"Vega Alonso","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Ordax D\u00edez","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Eugenio","family":"Lozano Alonso","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Rojo Bello","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacobo","family":"Mendioroz","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Basile","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Isabel","family":"Mart\u00ednez Mateo","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlota","family":"Ruiz de Porras","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Moya Garc\u00e9s","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00aa \u00c1ngeles","family":"Marcos","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"L\u00f3pez Maside","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesc","family":"Botella Quijal","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maite","family":"Miralles Espi","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Andreu Salete","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda del Carmen","family":"Garc\u00eda Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Antonio","family":"Linares","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Garc\u00eda Comas","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00aa Isabel","family":"Barranco","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda-Dolores","family":"Chirlaque","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Moreno Doc\u00f3n","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violeta","family":"Ramos Mar\u00edn","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Castrillejo","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atanasio","family":"G\u00f3mez An\u00e9s","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amparo","family":"Larrauro","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"P\u00e9rez-Gimeno","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos","family":"Lozano \u00c1lvarez","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Vega","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Galindo","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tania","family":"Puma","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Monge","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Pozo","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inmaculada","family":"Casas","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Sandonis","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"V\u00e1zquez-Mor\u00f3n","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aitziber","family":"Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camino","family":"Trobajo-Sanmart\u00edn","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Garc\u00eda Cenoz","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Ezpeleta","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Ezpeleta","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Navascu\u00e9s","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Krisztalovics","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisztina","family":"Mucs\u00e1nyin\u00e9 Juh\u00e1sz","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Krist\u00f3f","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ute","family":"Preuss","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianne","family":"Wedde","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Biere","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine","family":"Reiche","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Djin-Ye","family":"Oh","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adele","family":"McKenna","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeff","family":"Connell","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Joyce","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariam","family":"Bagheri","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanne","family":"Bos","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"van den Brink","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederika","family":"Dijkstra","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Eggink","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rianne","family":"van Gageldonk-Lafeber","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Goderski","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chantal","family":"Herrebrugh","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liz","family":"Jenniskens","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne","family":"Reukers","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Sluimer","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tara","family":"Sprong","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Teirlinck","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nienke","family":"Veldhijzen","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruben","family":"van der Burgh","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrien","family":"Kager","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayra","family":"Klinkhamer","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart","family":"Knottnerus","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marloes","family":"Riethof","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruud","family":"van den Broek","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safira","family":"Wortel","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ausenda","family":"Machado","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Kislaya","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Aniceto","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lic\u00ednia","family":"Gomes","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuno","family":"Verdasca","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Henriques","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Dias","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Lan\u00e7a","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Blanchon","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Guerrisi","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aubane","family":"Renard","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Titouan","family":"Launay","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley","family":"Masse","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie","family":"Chazelle","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Feren\u010dak","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Kai\u0107","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vesna","family":"Vi\u0161ekruna Vu\u010dina","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katica","family":"\u010cusek Adami\u0107","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjana Lana","family":"Kosanovi\u0107 Li\u010dina","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danijela","family":"Lako\u0161eljac","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Mihin Huski\u0107","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Nonkovi\u0107","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annasara","family":"Carnahan","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Hansson-Pihlainen","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elin","family":"Arvesen","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"Nid","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna-Lena","family":"Hansen","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmi","family":"Andersson","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lena","family":"Dillner","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Jidovu","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia Carmen","family":"Timnea","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u0103t\u0103lina","family":"Pascu","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Oprea","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iulia","family":"Bistriceanu","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina","family":"Ivanciuc","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Elena","family":"Mihai","sequence":"additional","affiliation":[{"name":"for the VEBIS Primary Care Vaccine Effectiveness Group"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"issue":"5","key":"zoi240627r5","doi-asserted-by":"publisher","first-page":"119","DOI":"10.15585\/mmwr.mm7205e1","article-title":"Early estimates of bivalent mRNA booster dose vaccine effectiveness in preventing symptomatic SARS-CoV-2 infection attributable to Omicron BA.5- and XBB\/XBB.1.5-related sublineages among immunocompetent adults\u2014increasing community access to testing program, United States, December 2022-January 2023.","volume":"72","author":"Link-Gelles","year":"2023","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"29","key":"zoi240627r7","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2021.26.29.2100670","article-title":"Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021.","volume":"26","author":"Kissling","year":"2021","journal-title":"Euro Surveill"},{"issue":"32","key":"zoi240627r8","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2023.28.32.2300397","article-title":"Relative effectiveness of bivalent original\/Omicron BA.4-5 mRNA vaccine in preventing severe COVID-19 in persons 60 years and above during SARS-CoV-2 Omicron XBB.1.5 and other XBB sublineages circulation, Italy, April to June 2023.","volume":"28","author":"Fabiani","year":"2023","journal-title":"Euro Surveill"},{"issue":"1","key":"zoi240627r10","doi-asserted-by":"publisher","first-page":"3886","DOI":"10.1038\/s41598-023-31057-1","article-title":"Seasonal trends in COVID-19 cases, hospitalizations, and mortality in the United States and Europe.","volume":"13","author":"Wiemken","year":"2023","journal-title":"Sci Rep"},{"issue":"8","key":"zoi240627r11","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/S1473-3099(23)00122-6","article-title":"Effectiveness of a bivalent mRNA vaccine booster dose to prevent severe COVID-19 outcomes: a retrospective cohort study.","volume":"23","author":"Arbel","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"zoi240627r12","doi-asserted-by":"publisher","DOI":"10.1172\/JCI162192","article-title":"Impact of antigenic evolution and original antigenic sin on SARS-CoV-2 immunity.","volume":"133","author":"Aguilar-Bretones","year":"2023","journal-title":"J Clin Invest"},{"key":"zoi240627r13","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1288794","article-title":"Systematical assessment of the impact of single spike mutations of SARS-CoV-2 Omicron sub-variants on the neutralization capacity of post-vaccination sera.","volume":"14","author":"Katzmarzyk","year":"2023","journal-title":"Front Immunol"},{"issue":"7911","key":"zoi240627r14","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/s41586-022-04690-5","article-title":"Defining the risk of SARS-CoV-2 variants on immune protection.","volume":"605","author":"DeGrace","year":"2022","journal-title":"Nature"},{"issue":"13","key":"zoi240627r16","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2024.29.13.2300403","article-title":"COVID-19 vaccine effectiveness against symptomatic infection with SARS-CoV-2 BA.1\/BA.2 lineages among adults and adolescents in a multicentre primary care study, Europe, December 2021 to June 2022.","volume":"29","author":"Lani\u00e8ce Delaunay","year":"2024","journal-title":"Euro Surveill"},{"issue":"21","key":"zoi240627r17","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2023.28.21.2300116","article-title":"Interim 2022\/23 influenza vaccine effectiveness: six European studies, October 2022 to January 2023.","volume":"28","author":"Kissling","year":"2023","journal-title":"Euro Surveill"},{"issue":"1","key":"zoi240627r18","doi-asserted-by":"publisher","DOI":"10.1111\/irv.v17.1","article-title":"Influenza vaccine effectiveness against influenza A subtypes in Europe: results from the 2021-2022 I-MOVE primary care multicentre study.","volume":"17","author":"Kissling","year":"2023","journal-title":"Influenza Other Respir Viruses"},{"issue":"21","key":"zoi240627r19","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.21.2101104","article-title":"Effectiveness of complete primary vaccination against COVID-19 at primary care and community level during predominant Delta circulation in Europe: multicentre analysis, I-MOVE-COVID-19 and ECDC networks, July to August 2021.","volume":"27","author":"Kissling","year":"2022","journal-title":"Euro Surveill"},{"issue":"49","key":"zoi240627r21","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.46234\/ccdcw2021.255","article-title":"GISAID\u2019s role in pandemic response.","volume":"3","author":"Khare","year":"2021","journal-title":"China CDC Wkly"},{"issue":"1","key":"zoi240627r24","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/biomet\/80.1.27","article-title":"Bias reduction of maximum likelihood estimates.","volume":"80","author":"Firth","year":"1993","journal-title":"Biometrika"},{"issue":"10","key":"zoi240627r25","first-page":"1071","article-title":"Regression models for prognostic prediction: advantages, problems, and suggested solutions.","volume":"69","author":"Harrell","year":"1985","journal-title":"Cancer Treat Rep"},{"issue":"12","key":"zoi240627r26","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis.","volume":"49","author":"Peduzzi","year":"1996","journal-title":"J Clin Epidemiol"},{"issue":"6","key":"zoi240627r27","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1093\/aje\/kwk052","article-title":"Relaxing the rule of ten events per variable in logistic and Cox regression.","volume":"165","author":"Vittinghoff","year":"2007","journal-title":"Am J Epidemiol"},{"issue":"12","key":"zoi240627r28","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1016\/S2213-2600(23)00306-5","article-title":"Effectiveness of BNT162b2 BA.4\/5 bivalent mRNA vaccine against a range of COVID-19 outcomes in a large health system in the USA: a test-negative case-control study.","volume":"11","author":"Tartof","year":"2023","journal-title":"Lancet Respir Med"},{"issue":"5","key":"zoi240627r29","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1093\/aje\/kwac015","article-title":"Identifying and alleviating bias due to differential depletion of susceptible people in postmarketing evaluations of COVID-19 vaccines.","volume":"191","author":"Kahn","year":"2022","journal-title":"Am J Epidemiol"},{"issue":"10379","key":"zoi240627r30","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/S0140-6736(22)02465-5","article-title":"Past SARS-CoV-2 infection protection against re-infection: a systematic review and meta-analysis.","volume":"401","author":"Stein","year":"2023","journal-title":"Lancet"},{"issue":"4","key":"zoi240627r31","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1016\/S1473-3099(22)00729-0","article-title":"Protection against symptomatic infection with Delta (B.1.617.2) and Omicron (B.1.1.529) BA.1 and BA.2 SARS-CoV-2 variants after previous infection and vaccination in adolescents in England, August, 2021-March, 2022: a national, observational, test-negative, case-control study.","volume":"23","author":"Powell","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"6","key":"zoi240627r32","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1136\/bmjebm-2021-111901","article-title":"Factors influencing estimated effectiveness of COVID-19 vaccines in non-randomised studies.","volume":"27","author":"Ioannidis","year":"2022","journal-title":"BMJ Evid Based Med"},{"key":"zoi240627r22","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4757-3462-1","volume-title":"Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis","author":"Harrell","year":"2001"},{"key":"zoi240627r23","volume-title":"International Encyclopedia of Statistical Science","author":"Akaike","year":"2011"},{"key":"zoi240627r1","unstructured":"European Centre for Disease Prevention and Control. Data on SARS-CoV-2 variants in the EU\/EEA. 2023. Accessed December 4, 2023. https:\/\/www.ecdc.europa.eu\/en\/publications-data\/data-virus-variants-covid-19-eueea"},{"key":"zoi240627r2","unstructured":"European Medicines Agency. First adapted COVID-19 booster vaccines recommended for approval in the EU. 2022. Accessed May 16, 2024. https:\/\/www.ema.europa.eu\/en\/news\/first-adapted-covid-19-booster-vaccines-recommended-approval-eu"},{"key":"zoi240627r3","unstructured":"European Centre for Disease Prevention and Control. Overview of the implementation of COVID-19 vaccination strategies and deployment plans in the EU\/EEA. 2022. Accessed May 16, 2024. https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/Overview-vaccination-strategies-COVID-19-8-September-2022.pdf"},{"key":"zoi240627r4","unstructured":"Haute Autorit\u00e9 de Sant\u00e9. Covid-19: la HAS int\u00e8gre les vaccins bivalents dans la strat\u00e9gie de vaccination pour l\u2019automne. 2022. Accessed May 16, 2024. https:\/\/www.has-sante.fr\/jcms\/p_3368002\/fr\/covid-19-la-has-integre-les-vaccins-bivalents-dans-la-strategie-de-vaccination-pour-l-automne#toc_1_1_2"},{"key":"zoi240627r6","unstructured":"European Centre for Disease Prevention and Control. Interim COVID-19 vaccination coverage in the EU\/EEA during the 2023\u201324 season campaigns. 2024. Accessed April 19, 2024. https:\/\/www.ecdc.europa.eu\/sites\/default\/files\/documents\/interim-vaccine-overage-eu-eea-2023-24.pdf"},{"key":"zoi240627r9","unstructured":"European Centre for Disease Prevention and Control. COVID-19 vaccine tracker. 2023. Accessed December 4, 2023. https:\/\/vaccinetracker.ecdc.europa.eu\/public\/extensions\/COVID-19\/vaccine-tracker.html#uptake-tab"},{"key":"zoi240627r15","unstructured":"European Centre for Disease Prevention and Control. Core protocol for ECDC studies of vaccine effectiveness against symptomatic laboratory-confirmed influenza or SARS-CoV-2 infection at primary care level. 2023. Accessed May 16, 2024. https:\/\/www.ecdc.europa.eu\/en\/publications-data\/core-protocol-ecdc-studies-vaccine-effectiveness-against-symptomatic-laboratory"},{"key":"zoi240627r20","unstructured":"European Commission. Commission implementing decision (EU) 2018\/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions: 2009. Accessed May 6, 2022. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/PDF\/?uri=CELEX:32018D0945"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2820602\/laniece_delaunay_2024_oi_240627_1719248987.19434.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T15:02:38Z","timestamp":1719846158000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2820602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.19258","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,1]]}}}