{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:33:40Z","timestamp":1792452820866,"version":"4.5.0"},"reference-count":53,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"Importance<\/jats:title>Older adults who are hospitalized for COVID-19 are at risk of delirium. Little is known about the association of in-hospital delirium with functional and cognitive outcomes among older adults who have survived a COVID-19 hospitalization.<\/jats:p><\/jats:sec>Objective<\/jats:title>To evaluate the association of delirium with functional disability and cognitive impairment over the 6 months after discharge among older adults hospitalized with COVID-19.<\/jats:p><\/jats:sec>Design, Setting, and Participants<\/jats:title>This prospective cohort study involved patients aged 60 years or older who were hospitalized with COVID-19 between June 18, 2020, and June 30, 2021, at 5 hospitals in a major tertiary care system in the US. Follow-up occurred through January 11, 2022. Data analysis was performed from December 2022 to February 2024.<\/jats:p><\/jats:sec>Exposure<\/jats:title>Delirium during the COVID-19 hospitalization was assessed using the Chart-based Delirium Identification Instrument (CHART-DEL) and CHART-DEL-ICU.<\/jats:p><\/jats:sec>Main Outcomes and Measures<\/jats:title>Primary outcomes were disability in 15 functional activities and the presence of cognitive impairment (defined as Montreal Cognitive Assessment score &amp;lt;22) at 1, 3, and 6 months after hospital discharge. The associations of in-hospital delirium with functional disability and cognitive impairment were evaluated using zero-inflated negative binominal and logistic regression models, respectively, with adjustment for age, month of follow-up, and baseline (before COVID-19) measures of the respective outcome.<\/jats:p><\/jats:sec>Results<\/jats:title>The cohort included 311 older adults (mean [SD] age, 71.3 [8.5] years; 163 female [52.4%]) who survived COVID-19 hospitalization. In the functional disability sample of 311 participants, 49 participants (15.8%) experienced in-hospital delirium. In the cognition sample of 271 participants, 31 (11.4%) experienced in-hospital delirium. In-hospital delirium was associated with both increased functional disability (rate ratio, 1.32; 95% CI, 1.05-1.66) and increased cognitive impairment (odds ratio, 2.48; 95% CI, 1.38-4.82) over the 6 months after discharge from the COVID-19 hospitalization.<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>In this cohort study of 311 hospitalized older adults with COVID-19, in-hospital delirium was associated with increased functional disability and cognitive impairment over the 6 months following discharge. Older survivors of a COVID-19 hospitalization who experience in-hospital delirium should be assessed for disability and cognitive impairment during postdischarge follow-up.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.19640","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:40:18Z","timestamp":1719934818000},"page":"e2419640","source":"Crossref","is-referenced-by-count":25,"title":["In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization"],"prefix":"10.1001","volume":"7","author":[{"given":"Ramya","family":"Kaushik","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail J.","family":"McAvay","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terrence E.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Acampora","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Araujo","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Charpentier","sequence":"additional","affiliation":[{"name":"CRI Web Tools, Durham, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumon","family":"Chattopadhyay","sequence":"additional","affiliation":[{"name":"Clinical and Translational Science Institute, University of Utah, Salt Lake City"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Geda","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M.","family":"Gill","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamar A.","family":"Kaminski","sequence":"additional","affiliation":[{"name":"Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seohyuk","family":"Lee","sequence":"additional","affiliation":[{"name":"Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Li","sequence":"additional","affiliation":[{"name":"Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew B.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra M.","family":"Hajduk","sequence":"additional","affiliation":[{"name":"Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Ferrante","sequence":"additional","affiliation":[{"name":"Section of Pulmonary Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2024,7,2]]},"reference":[{"key":"zoi240635r1","doi-asserted-by":"publisher","first-page":"343","DOI":"10.15585\/mmwr.mm6912e2","article-title":"Severe outcomes among patients with coronavirus disease 2019 (COVID-19)\u2014United States, February 12-March 16, 2020.","volume":"69","author":"CDC COVID-19 Response Team","year":"2020","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"11","key":"zoi240635r2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.29540","article-title":"Delirium in older patients with COVID-19 presenting to the emergency department.","volume":"3","author":"Kennedy","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"23","key":"zoi240635r3","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.1056\/NEJMc2008597","article-title":"Neurologic features in severe SARS-CoV-2 infection.","volume":"382","author":"Helms","year":"2020","journal-title":"N Engl J Med"},{"issue":"11","key":"zoi240635r4","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1111\/jgs.v68.11","article-title":"Delirium and adverse outcomes in hospitalized patients with COVID-19.","volume":"68","author":"Garcez","year":"2020","journal-title":"J Am Geriatr Soc"},{"issue":"5","key":"zoi240635r5","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.v36.5","article-title":"Neurological manifestations in patients with COVID-19: a systematic review and meta-analysis.","volume":"36","author":"Mahdizade Ari","year":"2022","journal-title":"J Clin Lab Anal"},{"issue":"11","key":"zoi240635r6","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1001\/jama.1996.03530350034031","article-title":"Precipitating factors for delirium in hospitalized elderly persons: predictive model and interrelationship with baseline vulnerability.","volume":"275","author":"Inouye","year":"1996","journal-title":"JAMA"},{"issue":"9920","key":"zoi240635r7","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1016\/S0140-6736(13)60688-1","article-title":"Delirium in elderly people.","volume":"383","author":"Inouye","year":"2014","journal-title":"Lancet"},{"issue":"16","key":"zoi240635r8","doi-asserted-by":"publisher","first-page":"5346","DOI":"10.3390\/jcm12165346","article-title":"Delirium and its association with short- and long-term health outcomes in medically admitted patients: a prospective study.","volume":"12","author":"Al Huraizi","year":"2023","journal-title":"J Clin Med"},{"issue":"4","key":"zoi240635r9","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1111\/jgs.2010.58.issue-4","article-title":"Delirium: an independent predictor of functional decline after cardiac surgery.","volume":"58","author":"Rudolph","year":"2010","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"zoi240635r10","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1001\/jama.2010.1013","article-title":"Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: a meta-analysis.","volume":"304","author":"Witlox","year":"2010","journal-title":"JAMA"},{"issue":"7","key":"zoi240635r11","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/j.jalz.2016.03.005","article-title":"The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients.","volume":"12","author":"Inouye","year":"2016","journal-title":"Alzheimers Dement"},{"issue":"17","key":"zoi240635r12","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1001\/jama.2021.2211","article-title":"The importance of delirium and delirium prevention in older adults during lockdowns.","volume":"325","author":"Inouye","year":"2021","journal-title":"JAMA"},{"issue":"7","key":"zoi240635r13","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/S2215-0366(20)30203-0","article-title":"Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic.","volume":"7","author":"Rogers","year":"2020","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"zoi240635r14","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1111\/jgs.v71.3","article-title":"Rationale, design, and characteristics of the VALIANT (COVID-19 in Older Adults: A Longitudinal Assessment) cohort.","volume":"71","author":"Cohen","year":"2023","journal-title":"J Am Geriatr Soc"},{"issue":"8","key":"zoi240635r15","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1001\/archpsyc.64.8.966","article-title":"A new brief instrument for assessing decisional capacity for clinical research.","volume":"64","author":"Jeste","year":"2007","journal-title":"Arch Gen Psychiatry"},{"issue":"4","key":"zoi240635r16","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"issue":"2","key":"zoi240635r17","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1111\/jgs.2000.48.issue-2","article-title":"Functional status before hospitalization in acutely ill older adults: validity and clinical importance of retrospective reports.","volume":"48","author":"Covinsky","year":"2000","journal-title":"J Am Geriatr Soc"},{"issue":"9","key":"zoi240635r18","doi-asserted-by":"publisher","first-page":"1206","DOI":"10.1093\/jamia\/ocy070","article-title":"Unstructured clinical documentation reflecting cognitive and behavioral dysfunction: toward an EHR-based phenotype for cognitive impairment.","volume":"25","author":"Gilmore-Bykovskyi","year":"2018","journal-title":"J Am Med Inform Assoc"},{"issue":"5","key":"zoi240635r19","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1097\/CCM.0b013e31819def97","article-title":"The Sequential Organ Failure Assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation.","volume":"37","author":"Jones","year":"2009","journal-title":"Crit Care Med"},{"issue":"11","key":"zoi240635r21","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1001\/archinte.163.11.1317","article-title":"Restricted activity and functional decline among community-living older persons.","volume":"163","author":"Gill","year":"2003","journal-title":"Arch Intern Med"},{"issue":"3","key":"zoi240635r22","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/geront\/9.3_Part_1.179","article-title":"Assessment of older people: self-maintaining and instrumental activities of daily living.","volume":"9","author":"Lawton","year":"1969","journal-title":"Gerontologist"},{"issue":"4","key":"zoi240635r23","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1093\/geront\/gnu067","article-title":"Disentangling the disabling process: insights from the precipitating events project.","volume":"54","author":"Gill","year":"2014","journal-title":"Gerontologist"},{"issue":"5","key":"zoi240635r24","doi-asserted-by":"publisher","first-page":"313","DOI":"10.7326\/0003-4819-135-5-200109040-00007","article-title":"Restricted activity among community-living older persons: incidence, precipitants, and health care utilization.","volume":"135","author":"Gill","year":"2001","journal-title":"Ann Intern Med"},{"issue":"4","key":"zoi240635r25","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1001\/jamainternmed.2014.7889","article-title":"Functional trajectories among older persons before and after critical illness.","volume":"175","author":"Ferrante","year":"2015","journal-title":"JAMA Intern Med"},{"issue":"4","key":"zoi240635r26","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1161\/STROKEAHA.114.007253","article-title":"Montreal Cognitive Assessment 5-minute protocol is a brief, valid, reliable, and feasible cognitive screen for telephone administration.","volume":"46","author":"Wong","year":"2015","journal-title":"Stroke"},{"issue":"5","key":"zoi240635r27","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1002\/gps.v33.5","article-title":"Converting MMSE to MoCA and MoCA 5-minute protocol in an educationally heterogeneous sample with stroke or transient ischemic attack.","volume":"33","author":"Wong","year":"2018","journal-title":"Int J Geriatr Psychiatry"},{"issue":"2","key":"zoi240635r28","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1111\/jgs.2005.53.issue-2","article-title":"A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method.","volume":"53","author":"Inouye","year":"2005","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"zoi240635r29","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1111\/jgs.v69.4","article-title":"Adaptation and validation of a chart-based delirium detection tool for the ICU (CHART-DEL-ICU).","volume":"69","author":"Krewulak","year":"2021","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"zoi240635r32","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1111\/jgs.v69.2","article-title":"Delirium in patients with SARS-CoV-2 infection: a multicenter study.","volume":"69","author":"Rebora","year":"2021","journal-title":"J Am Geriatr Soc"},{"issue":"1","key":"zoi240635r33","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1186\/s13054-020-02882-x","article-title":"COVID-19: ICU delirium management during SARS-CoV-2 pandemic.","volume":"24","author":"Kotfis","year":"2020","journal-title":"Crit Care"},{"issue":"3","key":"zoi240635r34","doi-asserted-by":"publisher","first-page":"E692","DOI":"10.9778\/cmajo.20210176","article-title":"Characteristics, treatment and delirium incidence of older adults hospitalized with COVID-19: a multicentre retrospective cohort study.","volume":"10","author":"Wong","year":"2022","journal-title":"CMAJ Open"},{"key":"zoi240635r35","doi-asserted-by":"publisher","DOI":"10.1002\/gps.v37.10","article-title":"Delirium in older COVID-19 patients: evaluating risk factors and outcomes.","author":"Kroon","year":"2022","journal-title":"Int J Geriatr Psychiatry"},{"issue":"10","key":"zoi240635r36","doi-asserted-by":"publisher","first-page":"2159","DOI":"10.1007\/s40520-020-01699-6","article-title":"Delirium in COVID-19: epidemiology and clinical correlations in a large group of patients admitted to an academic hospital.","volume":"32","author":"Ticinesi","year":"2020","journal-title":"Aging Clin Exp Res"},{"issue":"5","key":"zoi240635r37","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1007\/s41999-020-00353-8","article-title":"Functional and cognitive outcomes after COVID-19 delirium.","volume":"11","author":"Mcloughlin","year":"2020","journal-title":"Eur Geriatr Med"},{"issue":"5","key":"zoi240635r38","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1007\/s00406-021-01346-9","article-title":"Long-term consequences of COVID-19 on cognitive functioning up to 6 months after discharge: role of depression and impact on quality of life.","volume":"272","author":"Poletti","year":"2022","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"issue":"5","key":"zoi240635r39","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/S2215-0366(21)00084-5","article-title":"6-Month neurological and psychiatric outcomes in 236?379 survivors of COVID-19: a retrospective cohort study using electronic health records.","volume":"8","author":"Taquet","year":"2021","journal-title":"Lancet Psychiatry"},{"key":"zoi240635r40","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.euroneuro.2022.04.004","article-title":"Trajectory of cognitive impairments over 1 year after COVID-19 hospitalisation: pattern, severity, and functional implications.","volume":"59","author":"Miskowiak","year":"2022","journal-title":"Eur Neuropsychopharmacol"},{"issue":"7","key":"zoi240635r41","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1111\/ene.v29.7","article-title":"One-year cognitive follow-up of COVID-19 hospitalized patients.","volume":"29","author":"Ferrucci","year":"2022","journal-title":"Eur J Neurol"},{"issue":"8","key":"zoi240635r42","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1111\/aas.v66.8","article-title":"Long-term cognitive and functional status in Danish ICU patients with COVID-19.","volume":"66","author":"Weihe","year":"2022","journal-title":"Acta Anaesthesiol Scand"},{"issue":"1","key":"zoi240635r43","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1186\/s12877-021-02140-x","article-title":"Health-related quality of life, functional decline, and long-term mortality in older patients following hospitalisation due to COVID-19.","volume":"21","author":"Walle-Hansen","year":"2021","journal-title":"BMC Geriatr"},{"issue":"8","key":"zoi240635r44","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1111\/jgs.2006.54.issue-8","article-title":"Older adults discharged from the hospital with delirium: 1-year outcomes.","volume":"54","author":"McAvay","year":"2006","journal-title":"J Am Geriatr Soc"},{"issue":"2","key":"zoi240635r45","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.cger.2019.11.001","article-title":"Delirium in the elderly.","volume":"36","author":"Hshieh","year":"2020","journal-title":"Clin Geriatr Med"},{"issue":"15","key":"zoi240635r46","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1056\/NEJMcp1605501","article-title":"Delirium in hospitalized older adults.","volume":"377","author":"Marcantonio","year":"2017","journal-title":"N Engl J Med"},{"issue":"9","key":"zoi240635r47","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1056\/NEJM199903043400901","article-title":"A multicomponent intervention to prevent delirium in hospitalized older patients.","volume":"340","author":"Inouye","year":"1999","journal-title":"N Engl J Med"},{"issue":"10","key":"zoi240635r48","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.1111\/jgs.2006.54.issue-10","article-title":"Dissemination of the hospital elder life program: implementation, adaptation, and successes.","volume":"54","author":"Inouye","year":"2006","journal-title":"J Am Geriatr Soc"},{"issue":"8","key":"zoi240635r49","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/j.jamda.2023.05.032","article-title":"Clinicians\u2019 perceptions of a modified hospital elder life program for delirium prevention during COVID-19.","volume":"24","author":"Schulman-Green","year":"2023","journal-title":"J Am Med Dir Assoc"},{"issue":"9","key":"zoi240635r50","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3928\/00989134-20100330-02","article-title":"Feasibility of family participation in a delirium prevention program for hospitalized older adults.","volume":"36","author":"Rosenbloom-Brunton","year":"2010","journal-title":"J Gerontol Nurs"},{"key":"zoi240635r51","doi-asserted-by":"publisher","DOI":"10.1177\/14799731211015691","article-title":"Early experiences of rehabilitation for individuals post-COVID to improve fatigue, breathlessness exercise capacity and cognition: a cohort study.","author":"Daynes","year":"2021","journal-title":"Chron Respir Dis"},{"issue":"3","key":"zoi240635r52","doi-asserted-by":"publisher","first-page":"297","DOI":"10.14283\/jfa.2021.1","article-title":"Rehabilitation in adult post-COVID-19 patients in post-acute care with therapeutic exercise.","volume":"10","author":"Udina","year":"2021","journal-title":"J Frailty Aging"},{"issue":"1","key":"zoi240635r53","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1186\/s13063-022-06632-y","article-title":"Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise-CISCO-21.","volume":"23","author":"Morrow","year":"2022","journal-title":"Trials"},{"key":"zoi240635r30","volume-title":"SAS\/STAT\u00ae User\u2019s Guide","author":"SAS Institute Inc","year":"2020"},{"key":"zoi240635r31","author":"StataCorp","year":"2021"},{"key":"zoi240635r20","doi-asserted-by":"crossref","unstructured":"Arora? T, Simonov? M, Alausa? J, . The Yale Department of Medicine COVID-19 Data Explorer and Repository (DOM-CovX): an innovative approach to promoting collaborative scholarship during a pandemic.? medRxiv. Preprint posted online August 26, 2021. doi:10.1101\/2021.08.23.21262241","DOI":"10.1101\/2021.08.23.21262241"}],"container-title":["JAMA Network Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/articlepdf\/2820671\/kaushik_2024_oi_240635_1719332763.64735.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:40:24Z","timestamp":1719934824000},"score":1,"resource":{"primary":{"URL":"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2820671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,2]]},"references-count":53,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.19640","relation":{},"ISSN":["2574-3805"],"issn-type":[{"value":"2574-3805","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,2]]}}}