{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T02:50:55Z","timestamp":1792896655624,"version":"4.5.0"},"reference-count":32,"publisher":"American Medical Association (AMA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"\n Importance<\/jats:title>\n \n Universal screening to identify unfavorable lipid levels is recommended for US children aged 9 to 11 years and adolescents aged 17 to 21 years (hereafter,\n young adults<\/jats:italic>\n ); however, screening benefits in these individuals have been questioned. Current use of lipid screening and prevalence of elevated lipid measurements among US youths is not well understood.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To investigate the prevalence of ambulatory pediatric lipid screening and elevated or abnormal lipid measurements among US screened youths by patient characteristic and test type.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This cross-sectional study used data from the IQVIA Ambulatory Electronic Medical Record database and included youths aged 9 to 21 years with 1 or more valid measurement of height and weight during the observation period (2018-2021). Body mass index (BMI) was calculated and categorized using standard pediatric BMI percentiles (9-19 years) and adult BMI categories (\u226520 years). The data were analyzed from October 6, 2022, to January 18, 2023.<\/jats:p>\n <\/jats:sec>\n \n Main Outcomes and Measures<\/jats:title>\n Lipid measurements were defined as abnormal if 1 or more of the following test results was identified: total cholesterol (\u2265200 mg\/dL), low-density lipoprotein cholesterol (\u2265130 mg\/dL), very low-density lipoprotein cholesterol (\u226531 mg\/dL), non\u2013high-density lipoprotein cholesterol (\u2265145 mg\/dL), and triglycerides (\u2265100 mg\/dL for children aged 9 years or \u2265130 mg\/dL for patients aged 10-21 years). After adjustment for age group, sex, race and ethnicity, and BMI category, adjusted prevalence ratios (aPRs) and 95% CIs were calculated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Among 3\u202f226\u202f002 youths (23.9% aged 9-11 years, 34.8% aged 12-16 years, and 41.3% aged 17-21 years; 1\u202f723\u202f292 females [53.4%]; 60.0% White patients, 9.5% Black patients, and 2.4% Asian patients), 11.3% had 1 or more documented lipid screening tests. The frequency of lipid screening increased by age group (9-11 years, 9.0%; 12-16 years, 11.1%; 17-21 years, 12.9%) and BMI category (range, 9.2% [healthy weight] to 21.9% [severe obesity]). Among those screened, 30.2% had abnormal lipid levels. Compared with youths with a healthy weight, prevalence of an abnormal result was higher among those with overweight (aPR, 1.58; 95% CI, 1.56-1.61), moderate obesity (aPR, 2.16; 95% CI, 2.14-2.19), and severe obesity (aPR, 2.53; 95% CI, 2.50-2.57).<\/jats:p>\n <\/jats:sec>\n \n Conclusions and Relevance<\/jats:title>\n In this cross-sectional study of prevalence of lipid screening among US youths aged 9 to 21 years, approximately 1 in 10 were screened. Among them, abnormal lipid levels were identified in 1 in 3 youths overall and 1 in 2 youths with severe obesity. Health care professionals should consider implementing lipid screening among children aged 9 to 11 years, young adults aged 17 to 21 years, and all youths at high cardiovascular risk.<\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.21724","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T13:20:02Z","timestamp":1721740802000},"page":"e2421724","source":"Crossref","is-referenced-by-count":35,"title":["Pediatric Lipid Screening Prevalence Using Nationwide Electronic Medical Records"],"prefix":"10.1001","volume":"7","author":[{"given":"Angela M.","family":"Thompson-Paul","sequence":"first","affiliation":[{"name":"Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"},{"name":"US Public Health Service Commissioned Corps, Rockville, Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily M.","family":"Kraus","sequence":"additional","affiliation":[{"name":"Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"},{"name":"Public Health Informatics Institute, Task Force for Global Health, Decatur, Georgia"},{"name":"Kraushold Consulting, Denver, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renee M.","family":"Porter","sequence":"additional","affiliation":[{"name":"Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha L.","family":"Pierce","sequence":"additional","affiliation":[{"name":"Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmyla","family":"Kompaniyets","sequence":"additional","affiliation":[{"name":"Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahlia","family":"Sekkarie","sequence":"additional","affiliation":[{"name":"Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia"},{"name":"Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson B.","family":"Goodman","sequence":"additional","affiliation":[{"name":"US Public Health Service Commissioned Corps, 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