{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:59:13Z","timestamp":1793307553381,"version":"4.5.0"},"reference-count":54,"publisher":"American Medical Association (AMA)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"Importance<\/jats:title>It is widely known that individuals with adverse childhood experiences (ACEs) have an increased risk of abusing their own children, thereby perpetuating the cycle of violence. However, the association between ACEs and elder abuse perpetration has not been fully examined.<\/jats:p><\/jats:sec>Objective<\/jats:title>To examine the association between ACEs and elder abuse and the mediating factors.<\/jats:p><\/jats:sec>Design, Setting, and Participants<\/jats:title>This cross-sectional study used data collected via the self-administered Japan COVID-19 and Society Internet Survey from September 12 to October 19, 2022. Men and women aged 20 to 64 years who responded to related questions were included. Data were analyzed from July 2023 to April 2024.<\/jats:p><\/jats:sec>Exposures<\/jats:title>ACEs, defined as the experience of any of 7 items\u2014interpersonal loss (parental loss and parental divorce), family psychopathology (parental mental disease and violence in family), abuse (physical and psychological abuse), and neglect\u2014before the age of 18 years.<\/jats:p><\/jats:sec>Main Outcomes and Measures<\/jats:title>The primary outcome was the perpetration of physical and\/or psychological abuse against an older person (aged \u226565 years) self-reported via questionnaire. The direct and indirect effect estimates were determined using logistic regression analyses.<\/jats:p><\/jats:sec>Results<\/jats:title>Of a total of 13\u202f318 participants (mean [SD] age, 41.1\u2009[12.1] years; 6634 female [49.8%]), 1133 (8.5%) reported perpetrating violence against older adults. Compared with individuals without ACEs, the odds ratios (ORs) for perpetrating violence were 3.22 (95% CI, 2.74-3.79) for those with 1 ACE and 7.65 (95% CI, 6.41-9.13) for those with 2 or more ACEs. In the mediation analysis, factors with large indirect effect estimates included depression (OR, 1.13; 95% CI, 1.11-1.14; proportion mediated [PM], 18.6%), mental illness other than depression (OR, 1.12; 95% CI, 1.10-1.14; PM, 17.3%), and self-rated health (OR, 1.04; 95% CI, 1.03-1.05; PM, 6.0%).<\/jats:p><\/jats:sec>Conclusions and Relevance<\/jats:title>These findings suggest that intergenerational cycles of violence may extend to any vulnerable group, not only children but also older adults. Further research into the prevention of ACEs and breaking these cycles of violence is warranted.<\/jats:p><\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.36150","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T15:30:54Z","timestamp":1727451054000},"page":"e2436150","source":"Crossref","is-referenced-by-count":15,"title":["Intergenerational Chain of Violence, Adverse Childhood Experiences, and Elder Abuse Perpetration"],"prefix":"10.1001","volume":"7","author":[{"given":"Chie","family":"Koga","sequence":"first","affiliation":[{"name":"Research Center for Advanced Science and Technology, University of Tokyo, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taishi","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Institute of Health and Sport Sciences, University of Tsukuba, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Hanazato","sequence":"additional","affiliation":[{"name":"Center for Preventive Medical Sciences, Chiba University, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Nakagomi","sequence":"additional","affiliation":[{"name":"Center for Preventive Medical Sciences, Chiba University, Chiba, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Tabuchi","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology, Cancer Control Center, Osaka International Cancer Institute, Osaka, Japan"},{"name":"Division of Epidemiology, School of Public Health, Tohoku University, Graduate School of Medicine, Sendai, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10","published-online":{"date-parts":[[2024,9,27]]},"reference":[{"key":"zoi241068r1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2020.101891","article-title":"Intergenerational effects of childhood maltreatment: a systematic review of the parenting practices of adult survivors of childhood abuse, neglect, and violence.","volume":"80","author":"Greene","year":"2020","journal-title":"Clin Psychol Rev"},{"issue":"4","key":"zoi241068r2","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0749-3797(98)00017-8","article-title":"Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. 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