{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:51:15Z","timestamp":1793037075867,"version":"4.5.0"},"reference-count":46,"publisher":"American Medical Association (AMA)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JAMA Netw Open"],"abstract":"\n Importance<\/jats:title>\n Supervised pelvic floor muscle training (PFMT) has been recommended as the first-line treatment for women with stress urinary incontinence (SUI), but more evidence on whether adjunctive methods would provide additional benefits is needed.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To compare the efficacy of PFMT with or without a home-based pressure-mediated biofeedback (BF) device.<\/jats:p>\n <\/jats:sec>\n \n Design, Setting, and Participants<\/jats:title>\n This multicenter assessor-blinded randomized clinical trial was conducted in the obstetric clinics of 5 participating tertiary hospitals in China. Participants included eligible women with new-onset postpartum SUI who were enrolled from March 28, 2022, to October 13, 2023.<\/jats:p>\n <\/jats:sec>\n \n Intervention<\/jats:title>\n All participants received 3 months of supervised PFMT and were randomized to either the intervention (PFMT with a home-based pressure-mediated BF device) or the control group (home-based PFMT).<\/jats:p>\n <\/jats:sec>\n \n Main Outcome and Measures<\/jats:title>\n The primary outcome was the severity of urinary incontinence evaluated by the International Consultation on Incontinence Questionnaire\u2013Urinary Incontinence Short Form after 3 months of supervised PFMT. The secondary outcomes included the cure and improvement rates, PFM strength, quality of life, self-efficacy, and adherence.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 452 participants (median age, 34 [IQR, 31-36] years; median body mass index [calculated as the weight in kilograms divided by the height in square meters], 23.71 [IQR, 21.37-25.97]; median time since delivery, 50 [IQR, 43-61] days) were included in the analysis, with 223 in the intervention group and 229 in the control group. Compared with the control group, the intervention group achieved a significantly greater reduction in incontinence severity (median, 3.00 [IQR, 1.00-6.00] vs 2.00 [IQR, 0-4.00] points;\n z<\/jats:italic>\n \u2009=\u2009\u22123.05;\n P<\/jats:italic>\n \u2009=\u2009.002), significantly increased cure rate (45 of 223 [20.2%] vs 20 of 229 [8.7%];\n z<\/jats:italic>\n \u2009=\u200912.02;\n P<\/jats:italic>\n \u2009=\u2009.001) and improvement (132 of 223 [59.2%] vs 102 of 229 [44.5%];\n z<\/jats:italic>\n \u2009=\u20099.71;\n P<\/jats:italic>\n \u2009=\u2009.002), significantly greater pelvic floor muscle strength (median, 26.00 [IQR, 17.00-38.00] vs 21.00 [IQR, 13.50-33.50] cm H\n 2<\/jats:sub>\n O;\n z<\/jats:italic>\n \u2009=\u2009\u22122.28;\n P<\/jats:italic>\n \u2009=\u2009.02), and a significantly greater correlation between subjective and objective adherence (\n r<\/jats:italic>\n \u2009=\u20090.825 vs\n r<\/jats:italic>\n = 0.627).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion and Relevance<\/jats:title>\n In this randomized clinical trial, the efficacy of pressure-mediated BF combined with PFMT was superior to that of PFMT alone. These findings support the use of pressure-mediated BF devices for improving treatment outcomes for patients with SUI.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n ClinicalTrials.gov Identifier:\n NCT05115864<\/jats:ext-link>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1001\/jamanetworkopen.2024.42925","type":"journal-article","created":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T11:01:01Z","timestamp":1730804461000},"page":"e2442925","source":"Crossref","is-referenced-by-count":30,"title":["Pressure-Mediated Biofeedback With Pelvic Floor Muscle Training for Urinary Incontinence"],"prefix":"10.1001","volume":"7","author":[{"given":"Xiuqi","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Obstetric and Gynecologic Diseases, Beijing, 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Heibei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guorong","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Obstetric and Gynecologic Diseases, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Tongren Hospital, Shanghai Jiao Tong University, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiandi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shunyi Maternal and Children\u2019s Hospital of Beijing, Beijing, 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